Assessment of myocardial vasculature in chronic alcoholics without established cardiomyopathy.

Abstract:

:Myocardial pathology and cardiac functional abnormalities known to occur in association with chronic alcohol abuse have been attributed to a direct toxic effect of ethanol on the intra-myocardial vasculature: alcohol-induced occlusion of small arteries with consequent secondary ischaemia leads to individual myocyte loss, focal fibrosis and compensatory cardiac hypertrophy. To assess the intra-myocardial arterial vessels an interactive semiautomated, computerised, high-resolution, video image-analysing system was used and the findings from hearts of alcoholics were compared with normal hearts collected at autopsy. The elastic laminae, stained with Van Gieson's stain, acted as the reference points for measurement of the diameters, circumferences and thicknesses of the vessels assessed. It was not possible to demonstrate any statistically significant morphometric changes within intra-myocardial vasculature. The same technique used is readily adaptable for the assessment of the blood vessels in other organs and tissues.

journal_name

Int J Legal Med

authors

Ahmed AN,Elton RA,Busuttil A

doi

10.1007/BF01225513

subject

Has Abstract

pub_date

1996-01-01 00:00:00

pages

167-72

issue

4

eissn

0937-9827

issn

1437-1596

journal_volume

109

pub_type

杂志文章
  • Estimation of chronologic age using the aspartic acid racemization method. I. On human rib cartilage.

    abstract::Determinations of chronologic age are of great importance in forensic science. At present the aspartic acid racemization method on teeth provides one of the best means in adult individuals. However, if teeth are not available, some other stable tissue has to be used. In this study, the applicability of cartilage from ...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/BF01845611

    authors: Pfeiffer H,Mörnstad H,Teivens A

    更新日期:1995-01-01 00:00:00

  • Further sequence and length variation at the STR loci HumFES/FPS, HumVWA, HumFGA and D12S391.

    abstract::This paper reports population data and statistics for the HumFES/FPS, HumVWA, HumFGA and D12S391 loci in Austria. The sequences of some rare and new variant alleles which have been identified in the course of the present population study and other investigations are described. Sequence variation occurred in a HumFES/F...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/pl00007712

    authors: Dauber EM,Glock B,Schwartz DW,Mayr WR

    更新日期:2000-01-01 00:00:00

  • Are autopsies of help to the parents of SIDS victims? A follow-up on SIDS families.

    abstract::Little is known about what bereaved parents feel about the autopsy performed on their child. A multi-centre case control study of sudden infant death syndrome (SIDS) victims was carried out in Germany between 1998 and 2001, in which all infants had been autopsied. We performed a follow-up study 4-7 years after the par...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00414-006-0100-3

    authors: Vennemann MM,Rentsch C,Bajanowski T,Zimmer G

    更新日期:2006-11-01 00:00:00

  • Death by band-aid: fatal misuse of transdermal fentanyl patch.

    abstract::We present a case of fatal intoxication by the application of a transdermal fentanyl patch upon a superficial bleeding abrasion of a 2-year-old girl. The grandmother discovered the body of the child in bed at approximately 7 a.m. External examination revealed a properly developed, nourished, and hydrated child, with s...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-015-1209-z

    authors: Bakovic M,Nestic M,Mayer D

    更新日期:2015-11-01 00:00:00

  • Fatal poisonings where ethylmorphine from antitussive medications contributed to death.

    abstract::The hypothesis that antitussives containing ethylmorphine are abused by alcoholics and drug addicts and that this may lead to fatal poisonings where ethylmorphine causes or contributes to death was investigated. For this purpose 14 cases were analysed where a blood ethylmorphine concentration above the therapeutic lev...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s004140050253

    authors: Jonasson B,Jonasson U,Holmgren P,Saldeen T

    更新日期:1999-01-01 00:00:00

  • Assistance of ethyl glucuronide and ethyl sulfate in the interpretation of postmortem ethanol findings.

    abstract::Postmortem ethanol formation is a well-known problem in forensic toxicology. The aim of this study was to interpret findings of ethanol in blood, in a large collection of forensic autopsy cases, by use of the nonoxidative ethanol metabolites, ethyl glucuronide (EtG), and ethyl sulfate (EtS). In this study, according t...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-014-1031-z

    authors: Krabseth H,Mørland J,Høiseth G

    更新日期:2014-09-01 00:00:00

  • Distribution of artifactual gas on post-mortem multidetector computed tomography (MDCT).

    abstract:PURPOSE:We investigated the incidence and distribution of post-mortem gas detected with multidetector computed tomography (MDCT) to identify factors that could distinguish artifactual gas from cardiac air embolism. MATERIAL AND METHODS:MDCT data of 119 cadavers were retrospectively examined. Gas was semiquantitatively...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-010-0542-5

    authors: Egger C,Bize P,Vaucher P,Mosimann P,Schneider B,Dominguez A,Meuli R,Mangin P,Grabherr S

    更新日期:2012-01-01 00:00:00

  • Mutation rate estimates for 13 STR loci in a large population from Rio Grande do Sul, Southern Brazil.

    abstract::Short tandem repeat (STR) polymorphisms have been extensively used in forensic genetics analysis. Knowledge about the locus-specific mutation rates of STRs improves forensic probability calculations and interpretations of diversity data. To incorporate single-locus diversity information into autosomal STR mutation rat...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-011-0642-x

    authors: Mardini AC,Rodenbusch R,Schumacher S,Chula FG,Michelon CT,Gastaldo AZ,Maciel LP,de Matos Almeida SE,da Silva CM

    更新日期:2013-01-01 00:00:00

  • Morphological and immunohistochemical studies of the pituitary in sudden infant death syndrome (SIDS).

    abstract::The morphological structure and immunohistochemical reactions of 100 pituitaries from cases of SIDS children (58 males and 42 females, average age 5.34 +/- 3.12 months) were studied. Controls consisted of 19 pituitaries from children (14 males and 5 females, average age 5.63 +/- 2.52 months) with a clearly identifiabl...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1007/BF01225414

    authors: Reuss W,Saeger W,Bajanowski T

    更新日期:1994-01-01 00:00:00

  • Terminal ballistics of 7.62 mm NATO bullets: experiments in ordnance gelatin.

    abstract::Military rifle bullets are assumed to tumble 180 degrees in the target and end up facing backwards, but intact. It has been claimed, however, that a German version of the 7.62 mm x 51 (7.62 mm NATO) bullet may fragment at ranges up to 100 m. A lack of strength in the jacket, causing it to break at the cannelure when h...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/BF01369906

    authors: Knudsen PJ,Vigsnaes JS,Rasmussen R,Nissen PS

    更新日期:1995-01-01 00:00:00

  • Expression of heat-shock protein 70 (Hsp70) in the respiratory tract and lungs of fire victims.

    abstract::Immunohistochemical investigation of the respiratory tract and lungs of 63 fire victims revealed a statistically significant enhanced expression of heat-shock protein 70 (Hsp70) in the epiglottis, the trachea, and the main and the peripheral bronchi compared with a control group. In the fire victims, a strong expressi...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-006-0105-y

    authors: Marschall S,Rothschild MA,Bohnert M

    更新日期:2006-11-01 00:00:00

  • Frequency and influencing factors of cardiopulmonary resuscitation-related injuries during implementation of the American Heart Association 2010 Guidelines: a retrospective study based on autopsy and postmortem computed tomography.

    abstract:AIM:To determine the frequency of cardiopulmonary resuscitation (CPR)-related injuries and factors involved in their occurrence, data based on forensic autopsy and postmortem computed tomography (PMCT) during implementation of the 2010 American Heart Association Guidelines for CPR were studied. METHODS:We retrospectiv...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-017-1673-8

    authors: Yamaguchi R,Makino Y,Chiba F,Torimitsu S,Yajima D,Inokuchi G,Motomura A,Hashimoto M,Hoshioka Y,Shinozaki T,Iwase H

    更新日期:2017-11-01 00:00:00

  • Genetic study of 12 X-STRs in Malay population living in and around Kuala Lumpur using Investigator Argus X-12 kit.

    abstract::We investigated 12 X-chromosomal short tandem repeat (STR) polymorphisms in 283 unrelated Malay individuals (160 males and 123 females) living in and around Kuala Lumpur using the Investigator Argus X-12 kit. Heterozygosity among the present 12 X-STRs showed a distribution of from 55.3 to 93.5 %. The diversity values ...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-012-0705-7

    authors: Samejima M,Nakamura Y,Nambiar P,Minaguchi K

    更新日期:2012-07-01 00:00:00

  • Software for Y-haplogroup predictions: a word of caution.

    abstract::The development of online software designed for genetic studies has been exponentially growing, providing numerous benefits to the scientific community. However, they should be used with care, since some require adjustments. The efficiency of two programs for haplogroup prediction was tested with 119 samples of known ...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-009-0404-1

    authors: Muzzio M,Ramallo V,Motti JM,Santos MR,López Camelo JS,Bailliet G

    更新日期:2011-01-01 00:00:00

  • Determination of urinary catecholamines and metanephrines in cardiac deaths.

    abstract::The aim of this study was to measure catecholamines and their O-methylated metabolites in urine and vitreous humor collected in cardiac deaths and noncardiac control cases that underwent medicolegal investigations. Our first goal was to assess whether cardiac events of different types are characterized by different ca...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-015-1303-2

    authors: Hervet T,Grouzmann E,Grabherr S,Mangin P,Palmiere C

    更新日期:2016-07-01 00:00:00

  • Purification of STR-multiplex-amplified microsamples can enhance signal intensity in capillary electrophoresis.

    abstract::In this study, the effect of sample purification on total signal intensities of samples amplified with genRES MPX-2 (nine-locus multiplex) prior to capillary electrophoretic analysis has been investigated. Sample purification with the Qiaquick PCR purification kit led to an increase of the relative fluorescent signal ...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-001-0277-4

    authors: Lederer T,Braunschweiger G,Betz P,Seidl S

    更新日期:2002-06-01 00:00:00

  • A new technique for the postmortem detection of tooth-coloured dental restorations.

    abstract::Identification of unknown bodies is mainly made by dental examination and comparison with accurate dental records. Therefore it is necessary to examine the jaws carefully and to locate every tooth-coloured dental restoration. Overlooking dental fillings can make positive identification impossible. The technique descri...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s004140050138

    authors: Benthaus S,DuChesne A,Brinkmann B

    更新日期:1998-01-01 00:00:00

  • Duplication of DYS19 flanking regions in other parts of the Y chromosome.

    abstract::During the testing of alternative primers for the Y chromosome short tandem repeat marker DYS19, a duplicated region of the Y chromosome was discovered. The duplicated sequence is contained within GenBank accession AC006335 and has a high degree of homology with the DYS19 flanking region (GenBank accession AC017019) b...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-004-0436-5

    authors: Butler JM,Schoske R

    更新日期:2004-06-01 00:00:00

  • Impact of DNA degradation on massively parallel sequencing-based autosomal STR, iiSNP, and mitochondrial DNA typing systems.

    abstract::Biological samples, including skeletal remains exposed to environmental insults for extended periods of time, exhibit increasing levels of DNA damage and fragmentation. Human forensic identification methods typically use a combination of mitochondrial (mt) DNA sequencing and short tandem repeat (STR) analysis, which t...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-019-02110-4

    authors: Zavala EI,Rajagopal S,Perry GH,Kruzic I,Bašić Ž,Parsons TJ,Holland MM

    更新日期:2019-09-01 00:00:00

  • Diatomological mapping of water bodies in Chongqing section of the Yangtze River and Jialing River.

    abstract::The diagnosis of drowning is one of the most difficult in forensic medicine. Forensic diatomology has been proposed to be useful in solving the diagnosis of drowning and considered to be a reliable indicator of the site of drowning. The Yangtze River and Jialing River are the main rivers in the Chongqing area (China),...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-020-02297-x

    authors: Zhang L,Nie Q,Dai Y,Zhu S,Wang J,Wang W,Tan X,Zhang P,Li J

    更新日期:2020-07-01 00:00:00

  • DNA typing in cases of blood chimerism.

    abstract::A chimera is an organism whose cells derive from two or more distinct zygote lineages. and therefore two different blood cell populations circulate in one individual. To point out the potential pitfalls in forensic analysis, a set of triplets (a girl and two boys) who revealed blood chimerism was investigated with fou...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s004140050263

    authors: Milde A,Kühl-Burmeister R,Ritz-Timme S,Kaatsch HJ

    更新日期:1999-01-01 00:00:00

  • Postmortem interrogation of cardiac implantable electrical devices may clarify time and cause of death.

    abstract:BACKGROUND:Postmortem interrogation of cardiac implantable electrical devices (CIED) in autopsy is not routinely performed. Thus, it remains unclear whether an interrogation might clarify time and cause of death. METHODS:Seventy of 4401 patients (1.6%) undergoing autopsy in 2014 and 2015 presented with a CIED. The exp...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-018-1932-3

    authors: Riesinger L,Fichtner S,Schuhmann CG,Estner HL,Czermak T,Graw M,Fischer F,Lackermair K

    更新日期:2019-05-01 00:00:00

  • How taphonomic alteration affects the detection and imaging of striations in stab wounds.

    abstract::Stabbing with a kitchen knife is a common method of homicide in Europe. Serrated knives may leave tool markings (striations) in tissues. Documentation of striations is necessary for their use as forensic evidence. Traditional methods (physical casting and photography) have significant limitations, and micro-computed t...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-017-1715-2

    authors: Stanley SA,Hainsworth SV,Rutty GN

    更新日期:2018-03-01 00:00:00

  • The Kaiser's tooth.

    abstract::The recovery of DNA from teeth is usually associated with the destruction of the evidential tooth using, for instance a special grinding mill. In some cases, however, a minimal invasive method of DNA retrieval with a high recovery is required particularly when historical material has to be investigated. A tooth attrib...

    journal_title:International journal of legal medicine

    pub_type: 传,历史文章,杂志文章

    doi:10.1007/s00414-002-0336-5

    authors: Pfeiffer H,Benthaus S,Rolf B,Brinkmann B

    更新日期:2003-04-01 00:00:00

  • Genotyping of 75 SNPs using arrays for individual identification in five population groups.

    abstract::Single nucleotide polymorphism (SNP) typing offers promise to forensic genetics. Various strategies and panels for analyzing SNP markers for individual identification have been published. However, the best panels with fewer identity SNPs for all major population groups are still under discussion. This study aimed to f...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-015-1250-y

    authors: Hwa HL,Wu LS,Lin CY,Huang TY,Yin HI,Tseng LH,Lee JC

    更新日期:2016-01-01 00:00:00

  • Forensic evaluation of alleged wrist restraint/handcuff injuries in survivors of torture utilizing the Istanbul Protocol.

    abstract::Despite being a common form of abuse, there is a paucity of literature describing shackling and wrist restraint injuries among survivors of torture. Forensic evaluation of alleged wrist restraint/handcuff injuries in survivors of torture presents challenges to the evaluator, especially if the injuries are remote and d...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-020-02451-5

    authors: Neufeld MY,Kimball S,Stein AB,Crosby SS

    更新日期:2021-01-07 00:00:00

  • Human fatalities caused by wasp and bee stings in Sweden.

    abstract::Bee and wasp stings represent an uncommon cause of death. In a retrospective study of all fatalities due to venomous animals in Sweden during a 10-year-period, we found 19 fatalities due to wasps, 1 due to bees but none due to snake bite. This gives an annual incidence of 0.2 per million inhabitants. Most of the decea...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/BF01626039

    authors: Johansson B,Eriksson A,Ornehult L

    更新日期:1991-03-01 00:00:00

  • Different types of structural variation in STRs: HumFES/FPS, HumVWA and HumD21S11.

    abstract::Alleles of the STR systems HumFES/FPS, HumVWA and HumD21S11 were sequenced and analyzed. Sequence data revealed 3 different systems concerning the complexity of their sequence structure. HumFES/FPS belongs to the STR polymorphism with a simple repeat structure. Only 2 subtypes were found with a base substitution in th...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/BF01224779

    authors: Möller A,Meyer E,Brinkmann B

    更新日期:1994-01-01 00:00:00

  • Sudden infant death syndrome caused by cardiac arrhythmias: only a matter of genes encoding ion channels?

    abstract::Sudden infant death syndrome is the unexpected demise of a child younger than 1 year of age which remains unexplained after a complete autopsy investigation. Usually, it occurs during sleep, in males, and during the first 12 weeks of life. The pathophysiological mechanism underlying the death is unknown, and the letha...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s00414-016-1330-7

    authors: Sarquella-Brugada G,Campuzano O,Cesar S,Iglesias A,Fernandez A,Brugada J,Brugada R

    更新日期:2016-03-01 00:00:00

  • Isomers of fluoroamphetamines detected in forensic cases in Denmark.

    abstract::A study was performed on the detection, separation and quantification of isomers from the new designer drugs named fluoroamphetamines (FAs) in forensic cases in eastern Denmark. The drugs were detected in whole blood extracts by ultraperformance liquid chromatography with time of flight mass spectrometer (UPLC-TOF-MS)...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-012-0671-0

    authors: Johansen SS,Hansen TM

    更新日期:2012-07-01 00:00:00