Abstract:
:Myocardial pathology and cardiac functional abnormalities known to occur in association with chronic alcohol abuse have been attributed to a direct toxic effect of ethanol on the intra-myocardial vasculature: alcohol-induced occlusion of small arteries with consequent secondary ischaemia leads to individual myocyte loss, focal fibrosis and compensatory cardiac hypertrophy. To assess the intra-myocardial arterial vessels an interactive semiautomated, computerised, high-resolution, video image-analysing system was used and the findings from hearts of alcoholics were compared with normal hearts collected at autopsy. The elastic laminae, stained with Van Gieson's stain, acted as the reference points for measurement of the diameters, circumferences and thicknesses of the vessels assessed. It was not possible to demonstrate any statistically significant morphometric changes within intra-myocardial vasculature. The same technique used is readily adaptable for the assessment of the blood vessels in other organs and tissues.
journal_name
Int J Legal Medjournal_title
International journal of legal medicineauthors
Ahmed AN,Elton RA,Busuttil Adoi
10.1007/BF01225513subject
Has Abstractpub_date
1996-01-01 00:00:00pages
167-72issue
4eissn
0937-9827issn
1437-1596journal_volume
109pub_type
杂志文章abstract::Determinations of chronologic age are of great importance in forensic science. At present the aspartic acid racemization method on teeth provides one of the best means in adult individuals. However, if teeth are not available, some other stable tissue has to be used. In this study, the applicability of cartilage from ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF01845611
更新日期:1995-01-01 00:00:00
abstract::This paper reports population data and statistics for the HumFES/FPS, HumVWA, HumFGA and D12S391 loci in Austria. The sequences of some rare and new variant alleles which have been identified in the course of the present population study and other investigations are described. Sequence variation occurred in a HumFES/F...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/pl00007712
更新日期:2000-01-01 00:00:00
abstract::Little is known about what bereaved parents feel about the autopsy performed on their child. A multi-centre case control study of sudden infant death syndrome (SIDS) victims was carried out in Germany between 1998 and 2001, in which all infants had been autopsied. We performed a follow-up study 4-7 years after the par...
journal_title:International journal of legal medicine
pub_type: 杂志文章,多中心研究
doi:10.1007/s00414-006-0100-3
更新日期:2006-11-01 00:00:00
abstract::We present a case of fatal intoxication by the application of a transdermal fentanyl patch upon a superficial bleeding abrasion of a 2-year-old girl. The grandmother discovered the body of the child in bed at approximately 7 a.m. External examination revealed a properly developed, nourished, and hydrated child, with s...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-015-1209-z
更新日期:2015-11-01 00:00:00
abstract::The hypothesis that antitussives containing ethylmorphine are abused by alcoholics and drug addicts and that this may lead to fatal poisonings where ethylmorphine causes or contributes to death was investigated. For this purpose 14 cases were analysed where a blood ethylmorphine concentration above the therapeutic lev...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140050253
更新日期:1999-01-01 00:00:00
abstract::Postmortem ethanol formation is a well-known problem in forensic toxicology. The aim of this study was to interpret findings of ethanol in blood, in a large collection of forensic autopsy cases, by use of the nonoxidative ethanol metabolites, ethyl glucuronide (EtG), and ethyl sulfate (EtS). In this study, according t...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-014-1031-z
更新日期:2014-09-01 00:00:00
abstract:PURPOSE:We investigated the incidence and distribution of post-mortem gas detected with multidetector computed tomography (MDCT) to identify factors that could distinguish artifactual gas from cardiac air embolism. MATERIAL AND METHODS:MDCT data of 119 cadavers were retrospectively examined. Gas was semiquantitatively...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-010-0542-5
更新日期:2012-01-01 00:00:00
abstract::Short tandem repeat (STR) polymorphisms have been extensively used in forensic genetics analysis. Knowledge about the locus-specific mutation rates of STRs improves forensic probability calculations and interpretations of diversity data. To incorporate single-locus diversity information into autosomal STR mutation rat...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-011-0642-x
更新日期:2013-01-01 00:00:00
abstract::The morphological structure and immunohistochemical reactions of 100 pituitaries from cases of SIDS children (58 males and 42 females, average age 5.34 +/- 3.12 months) were studied. Controls consisted of 19 pituitaries from children (14 males and 5 females, average age 5.63 +/- 2.52 months) with a clearly identifiabl...
journal_title:International journal of legal medicine
pub_type: 杂志文章,多中心研究
doi:10.1007/BF01225414
更新日期:1994-01-01 00:00:00
abstract::Military rifle bullets are assumed to tumble 180 degrees in the target and end up facing backwards, but intact. It has been claimed, however, that a German version of the 7.62 mm x 51 (7.62 mm NATO) bullet may fragment at ranges up to 100 m. A lack of strength in the jacket, causing it to break at the cannelure when h...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF01369906
更新日期:1995-01-01 00:00:00
abstract::Immunohistochemical investigation of the respiratory tract and lungs of 63 fire victims revealed a statistically significant enhanced expression of heat-shock protein 70 (Hsp70) in the epiglottis, the trachea, and the main and the peripheral bronchi compared with a control group. In the fire victims, a strong expressi...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-006-0105-y
更新日期:2006-11-01 00:00:00
abstract:AIM:To determine the frequency of cardiopulmonary resuscitation (CPR)-related injuries and factors involved in their occurrence, data based on forensic autopsy and postmortem computed tomography (PMCT) during implementation of the 2010 American Heart Association Guidelines for CPR were studied. METHODS:We retrospectiv...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-017-1673-8
更新日期:2017-11-01 00:00:00
abstract::We investigated 12 X-chromosomal short tandem repeat (STR) polymorphisms in 283 unrelated Malay individuals (160 males and 123 females) living in and around Kuala Lumpur using the Investigator Argus X-12 kit. Heterozygosity among the present 12 X-STRs showed a distribution of from 55.3 to 93.5 %. The diversity values ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-012-0705-7
更新日期:2012-07-01 00:00:00
abstract::The development of online software designed for genetic studies has been exponentially growing, providing numerous benefits to the scientific community. However, they should be used with care, since some require adjustments. The efficiency of two programs for haplogroup prediction was tested with 119 samples of known ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-009-0404-1
更新日期:2011-01-01 00:00:00
abstract::The aim of this study was to measure catecholamines and their O-methylated metabolites in urine and vitreous humor collected in cardiac deaths and noncardiac control cases that underwent medicolegal investigations. Our first goal was to assess whether cardiac events of different types are characterized by different ca...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-015-1303-2
更新日期:2016-07-01 00:00:00
abstract::In this study, the effect of sample purification on total signal intensities of samples amplified with genRES MPX-2 (nine-locus multiplex) prior to capillary electrophoretic analysis has been investigated. Sample purification with the Qiaquick PCR purification kit led to an increase of the relative fluorescent signal ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-001-0277-4
更新日期:2002-06-01 00:00:00
abstract::Identification of unknown bodies is mainly made by dental examination and comparison with accurate dental records. Therefore it is necessary to examine the jaws carefully and to locate every tooth-coloured dental restoration. Overlooking dental fillings can make positive identification impossible. The technique descri...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140050138
更新日期:1998-01-01 00:00:00
abstract::During the testing of alternative primers for the Y chromosome short tandem repeat marker DYS19, a duplicated region of the Y chromosome was discovered. The duplicated sequence is contained within GenBank accession AC006335 and has a high degree of homology with the DYS19 flanking region (GenBank accession AC017019) b...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-004-0436-5
更新日期:2004-06-01 00:00:00
abstract::Biological samples, including skeletal remains exposed to environmental insults for extended periods of time, exhibit increasing levels of DNA damage and fragmentation. Human forensic identification methods typically use a combination of mitochondrial (mt) DNA sequencing and short tandem repeat (STR) analysis, which t...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-019-02110-4
更新日期:2019-09-01 00:00:00
abstract::The diagnosis of drowning is one of the most difficult in forensic medicine. Forensic diatomology has been proposed to be useful in solving the diagnosis of drowning and considered to be a reliable indicator of the site of drowning. The Yangtze River and Jialing River are the main rivers in the Chongqing area (China),...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-020-02297-x
更新日期:2020-07-01 00:00:00
abstract::A chimera is an organism whose cells derive from two or more distinct zygote lineages. and therefore two different blood cell populations circulate in one individual. To point out the potential pitfalls in forensic analysis, a set of triplets (a girl and two boys) who revealed blood chimerism was investigated with fou...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140050263
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:Postmortem interrogation of cardiac implantable electrical devices (CIED) in autopsy is not routinely performed. Thus, it remains unclear whether an interrogation might clarify time and cause of death. METHODS:Seventy of 4401 patients (1.6%) undergoing autopsy in 2014 and 2015 presented with a CIED. The exp...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-018-1932-3
更新日期:2019-05-01 00:00:00
abstract::Stabbing with a kitchen knife is a common method of homicide in Europe. Serrated knives may leave tool markings (striations) in tissues. Documentation of striations is necessary for their use as forensic evidence. Traditional methods (physical casting and photography) have significant limitations, and micro-computed t...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-017-1715-2
更新日期:2018-03-01 00:00:00
abstract::The recovery of DNA from teeth is usually associated with the destruction of the evidential tooth using, for instance a special grinding mill. In some cases, however, a minimal invasive method of DNA retrieval with a high recovery is required particularly when historical material has to be investigated. A tooth attrib...
journal_title:International journal of legal medicine
pub_type: 传,历史文章,杂志文章
doi:10.1007/s00414-002-0336-5
更新日期:2003-04-01 00:00:00
abstract::Single nucleotide polymorphism (SNP) typing offers promise to forensic genetics. Various strategies and panels for analyzing SNP markers for individual identification have been published. However, the best panels with fewer identity SNPs for all major population groups are still under discussion. This study aimed to f...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-015-1250-y
更新日期:2016-01-01 00:00:00
abstract::Despite being a common form of abuse, there is a paucity of literature describing shackling and wrist restraint injuries among survivors of torture. Forensic evaluation of alleged wrist restraint/handcuff injuries in survivors of torture presents challenges to the evaluator, especially if the injuries are remote and d...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-020-02451-5
更新日期:2021-01-07 00:00:00
abstract::Bee and wasp stings represent an uncommon cause of death. In a retrospective study of all fatalities due to venomous animals in Sweden during a 10-year-period, we found 19 fatalities due to wasps, 1 due to bees but none due to snake bite. This gives an annual incidence of 0.2 per million inhabitants. Most of the decea...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF01626039
更新日期:1991-03-01 00:00:00
abstract::Alleles of the STR systems HumFES/FPS, HumVWA and HumD21S11 were sequenced and analyzed. Sequence data revealed 3 different systems concerning the complexity of their sequence structure. HumFES/FPS belongs to the STR polymorphism with a simple repeat structure. Only 2 subtypes were found with a base substitution in th...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF01224779
更新日期:1994-01-01 00:00:00
abstract::Sudden infant death syndrome is the unexpected demise of a child younger than 1 year of age which remains unexplained after a complete autopsy investigation. Usually, it occurs during sleep, in males, and during the first 12 weeks of life. The pathophysiological mechanism underlying the death is unknown, and the letha...
journal_title:International journal of legal medicine
pub_type: 杂志文章,评审
doi:10.1007/s00414-016-1330-7
更新日期:2016-03-01 00:00:00
abstract::A study was performed on the detection, separation and quantification of isomers from the new designer drugs named fluoroamphetamines (FAs) in forensic cases in eastern Denmark. The drugs were detected in whole blood extracts by ultraperformance liquid chromatography with time of flight mass spectrometer (UPLC-TOF-MS)...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-012-0671-0
更新日期:2012-07-01 00:00:00