Abstract:
:The aim of this study was to measure catecholamines and their O-methylated metabolites in urine and vitreous humor collected in cardiac deaths and noncardiac control cases that underwent medicolegal investigations. Our first goal was to assess whether cardiac events of different types are characterized by different catecholamine/metanephrine urine and/or vitreous profiles. Our second goal was to determine whether noncardiac causes of death with different survival intervals are characterized by different catecholamine/metanephrine urine and/or vitreous profiles. Two study groups were prospectively and retrospectively formed, a cardiac death group (including three subgroups, according to the cause of death) and a noncardiac death group (including two subgroups, according to the length of the agonal period). Postmortem angiography, autopsy, histology, toxicology, and biochemistry were performed in all cases. First results seem to indicate that absolute values measured in urine and vitreous for each of the analyzed markers display no significant differences relating to each of the tested cardiac death subgroups. In the control group, absolute concentrations measured in urine and vitreous for each of the analyzed parameters failed to show significant differences relating to the length of agonal period. Our preliminary findings do not seem to confirm the conclusions of former studies and fail to corroborate the usefulness of urine catecholamine and metanephrine analysis to characterize stress response intensity or length of the dying process in the postmortem setting.
journal_name
Int J Legal Medjournal_title
International journal of legal medicineauthors
Hervet T,Grouzmann E,Grabherr S,Mangin P,Palmiere Cdoi
10.1007/s00414-015-1303-2subject
Has Abstractpub_date
2016-07-01 00:00:00pages
995-1001issue
4eissn
0937-9827issn
1437-1596pii
10.1007/s00414-015-1303-2journal_volume
130pub_type
杂志文章abstract::Plant exposures are among the most frequently reported cases to poison control centres worldwide. This is a growing condition due to recent societal trends oriented towards the consumption of wild plants as food, cosmetics, or medicine. At least three general causes of plant poisoning can be identified: plant misident...
journal_title:International journal of legal medicine
pub_type: 杂志文章,评审
doi:10.1007/s00414-016-1460-y
更新日期:2017-01-01 00:00:00
abstract::Diagnosis of ischaemia-related sudden cardiac death in the absence of microscopic and macroscopic ischaemic lesions remains a challenge for medical examiners. Medical imaging techniques increasingly provide support in post-mortem examinations by detecting and documenting internal findings prior to autopsy. Previous st...
journal_title:International journal of legal medicine
pub_type: 杂志文章
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abstract::The case concerns the sudden death of a 21-year-old male during a soccer game. The autopsy revealed large, calcified saccular aneurysms at the origins of both the left anterior descending and the right coronary arteries. Histologically, the wall of the aneurysms was thin and composed of an internal fibro-calcified lay...
journal_title:International journal of legal medicine
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abstract::BamHI polymorphism at the VNTR locus D2S44 was investigated, concentrating on band frequencies, mutation rate and confirmation of Mendelian inheritance. In this series 39 restriction fragments showing frequencies less than 10% could clearly be distinguished. No mutations could be observed and the Mendelian character o...
journal_title:International journal of legal medicine
pub_type: 杂志文章
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abstract::The allelic frequency distributions and statistical forensic parameters of 26 mini short tandem repeat (mini-STR) loci in a sample of 1575 unrelated individuals from five different Brazilian regions were obtained. All the analyzed loci showed great diversity and were highly informative. The results were compared with ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
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abstract::Alleles of the STR systems HumFES/FPS, HumVWA and HumD21S11 were sequenced and analyzed. Sequence data revealed 3 different systems concerning the complexity of their sequence structure. HumFES/FPS belongs to the STR polymorphism with a simple repeat structure. Only 2 subtypes were found with a base substitution in th...
journal_title:International journal of legal medicine
pub_type: 杂志文章
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abstract::Backspatter is the ejection of biological material from a gunshot entrance wound against the line of fire. This phenomenon was investigated experimentally in transverse gunshots to the heads of calves (n = 9) using two types of 9 mm Parabellum ammunition from shooting distances of 0-10 cm. The resulting bloodstains we...
journal_title:International journal of legal medicine
pub_type: 杂志文章
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abstract:AIM:The aim of the current study was to retrospectively collect dental panoramic radiographs from Somali children living in Finland, to use the radiographic data to develop a new age estimation model based on the model established by Willems et al. (J Forensic Sci 46(4):893-895, 2001), and to compare the age prediction...
journal_title:International journal of legal medicine
pub_type: 杂志文章
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更新日期:2018-11-01 00:00:00
abstract::A single-tube multiplex assay of a small set of ancestry-informative markers (AIMs) for effectively estimating individual ancestry and admixture is an ideal forensic tool to trace the population origin of an unknown DNA sample. We present a newly developed 27-plex single nucleotide polymorphism (SNP) panel with highly...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-015-1183-5
更新日期:2016-01-01 00:00:00
abstract::The likelihood ratio is the fundamental quantity that summarizes the evidence in forensic cases. Therefore, it is important to understand the theoretical properties of this statistic. This paper is the last in a series of three, and the first to study linked markers. We show that for all non-inbred pairwise kinship co...
journal_title:International journal of legal medicine
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journal_title:International journal of legal medicine
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更新日期:2013-11-01 00:00:00
abstract::The original version of this article unfortunately contained a mistake in the Results section. The correct equation from the cubic regression analysis for male is: Age = 14.408 + 0.475X-0.064X2 + 0.005X3, and for the female is: 18.196-1.637X + 0.204X2-0.005X3. The error doesn't affect the main conclusion. ...
journal_title:International journal of legal medicine
pub_type: 杂志文章,已发布勘误
doi:10.1007/s00414-017-1751-y
更新日期:2018-01-01 00:00:00
abstract::A cross-sectional study was carried out to assess chronological age estimation based on the stages of third lower molar development, following the eight stages (A-H) method of Demirjian et al. The final sample consisted of 1,054 orthopantomograms from Spanish individuals of known chronological age (range 14-21 years) ...
journal_title:International journal of legal medicine
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abstract::Forensic identification comprises legal, social, ethical, and religious aspects where age detection is an important factor. When the case is a fetus or infant, recording various measurements of the body, head, and teeth is essential. The aim of this research is to evaluate the effects of different tooth and body measu...
journal_title:International journal of legal medicine
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journal_title:International journal of legal medicine
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doi:10.1007/s00414-014-1138-2
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journal_title:International journal of legal medicine
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doi:10.1007/s00414-011-0588-z
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journal_title:International journal of legal medicine
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journal_title:International journal of legal medicine
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doi:10.1007/s00414-018-1845-1
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pub_type: 已发布勘误
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journal_title:International journal of legal medicine
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journal_title:International journal of legal medicine
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journal_title:International journal of legal medicine
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