Abstract:
:BamHI polymorphism at the VNTR locus D2S44 was investigated, concentrating on band frequencies, mutation rate and confirmation of Mendelian inheritance. In this series 39 restriction fragments showing frequencies less than 10% could clearly be distinguished. No mutations could be observed and the Mendelian character of inheritance is beyond reasonable doubt.
journal_name
Int J Legal Medjournal_title
International journal of legal medicineauthors
Henke L,Cleef S,Zakrzewska M,Henke Jdoi
10.1007/BF01816481subject
Has Abstractpub_date
1990-12-01 00:00:00pages
33-8issue
1eissn
0937-9827issn
1437-1596journal_volume
104pub_type
杂志文章abstract::The aim of this study was to measure catecholamines and their O-methylated metabolites in urine and vitreous humor collected in cardiac deaths and noncardiac control cases that underwent medicolegal investigations. Our first goal was to assess whether cardiac events of different types are characterized by different ca...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-015-1303-2
更新日期:2016-07-01 00:00:00
abstract::Cyanide (CN) blood concentration is hardly considered during routine when evaluating smoke gas intoxications and fire victims, although some inflammable materials release a considerable amount of hydrogen cyanide. CN can be significant for the capacity to act and can in the end even be the cause of death. Systematic d...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-016-1426-0
更新日期:2017-01-01 00:00:00
abstract::For the interpretation of the concentration of morphine in blood samples of heroin consumers information about the concentration of the analgesic active morphine metabolite morphine-6-glucuronide is very important. Thus a simple but specific clean-up procedure based on immuno-affinity chromatography is presented for t...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140050073
更新日期:1997-01-01 00:00:00
abstract::The original version of this article unfortunately contained a mistake in the Results section. The correct equation from the cubic regression analysis for male is: Age = 14.408 + 0.475X-0.064X2 + 0.005X3, and for the female is: 18.196-1.637X + 0.204X2-0.005X3. The error doesn't affect the main conclusion. ...
journal_title:International journal of legal medicine
pub_type: 杂志文章,已发布勘误
doi:10.1007/s00414-017-1751-y
更新日期:2018-01-01 00:00:00
abstract::Postmortem ethanol formation is a well-known problem in forensic toxicology. The aim of this study was to interpret findings of ethanol in blood, in a large collection of forensic autopsy cases, by use of the nonoxidative ethanol metabolites, ethyl glucuronide (EtG), and ethyl sulfate (EtS). In this study, according t...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-014-1031-z
更新日期:2014-09-01 00:00:00
abstract::The population origin of an individual is often requested to be determined from specimens left at a crime scene for identifying a suspect and individual identity. The melanocortin 1 receptor gene (MC1R) and P gene are associated with human pigmentation. Although several studies have reported that these genes are highl...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-008-0289-4
更新日期:2009-05-01 00:00:00
abstract::The assessment of age at death for identification purposes is a frequent and tough challenge for forensic pathologists and anthropologists. Too frequently, visual assessment of age is performed on well-preserved corpses, a method considered subjective and full of pitfalls, but whose level of inadequacy no one has yet ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-014-1042-9
更新日期:2015-07-01 00:00:00
abstract::In forensic science, the unequivocal identification of the cellular origin of crime scene samples used for DNA profiling can provide crucial information for crime scene reconstruction. We have previously shown that various mRNA markers from genes with expression patterns specific for blood and saliva can be establishe...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-008-0249-z
更新日期:2009-01-01 00:00:00
abstract::In this study the development of a 13-locus multiplex-PCR system fitting the updated demands for paternity testing in Germany is described. For this purpose an existing multiplex PCR system that allows the simultaneous amplification of eight different STR loci together with the sex-specific locus amelogenin ( genRESMP...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-003-0420-5
更新日期:2004-02-01 00:00:00
abstract::The case concerns the sudden death of a 21-year-old male during a soccer game. The autopsy revealed large, calcified saccular aneurysms at the origins of both the left anterior descending and the right coronary arteries. Histologically, the wall of the aneurysms was thin and composed of an internal fibro-calcified lay...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140050213
更新日期:1999-01-01 00:00:00
abstract::The sequences of the hypervariable region 1 (HV1) of the mitochondrial DNA control region from multiple hair shafts from 10 unrelated individuals were compared to determine the frequency of differences in hairs from one individual. The extraction method described herein showed an average success rate of 67% for all 15...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140050226
更新日期:1999-01-01 00:00:00
abstract::Ancestry informative markers (AIMs) can be used to detect and adjust for population stratification and predict the ancestry of the source of an evidence sample. Autosomal single nucleotide polymorphisms (SNPs) are the best candidates for AIMs. It is essential to identify the most informative AIM SNPs across relevant p...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-015-1297-9
更新日期:2016-03-01 00:00:00
abstract::The assistance provided by specialised healthcare personnel to victims of a sexual violence cannot focus just on the clinical intervention appropriate for the lesions suffered by the patient, but must also take legal and forensic needs into account. Anamnestic data represents a crucial step towards the finding of fore...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-017-1602-x
更新日期:2017-09-01 00:00:00
abstract::In order to increase the validity of age estimation in adolescents and young adults when there is no legitimation for X-ray examinations, it seems desirable to be able to assess the mineralization of third molars using X-ray-free imaging procedures. In the present study, the mineralization stages of lower third molars...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-015-1238-7
更新日期:2015-11-01 00:00:00
abstract::In this study, a total of 191 cases with STR exclusions out of 591 paternity cases were analysed using 2 STR sets, i.e. (set a) 5 STRs in 462 cases with 150 exclusions and (set b) 9 STRs in 129 cases with 41 exclusions. Set (a) was associated with four exclusions on average while set (b) showed five exclusionary loci ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140000174
更新日期:2001-01-01 00:00:00
abstract::A 49-year-old white male was found lying unconscious at home. He had vomited, his mouth was filled with a white foam and a pungent odour filled the room. After emergency treatment blood, urine and stomach contents were screened for drugs after acid and alkaline extraction with subsequent derivatisation and GC-MS analy...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140050080
更新日期:1997-01-01 00:00:00
abstract::We report a simultaneous study of the VWA STR locus by the Perkin-Elmer Profiler Plus kit and the Promega GenePrint CTTv kit in a population sample from North Portugal and in 418 meiosis from family material and paternity cases. PCR amplification and genotyping were performed according to the manufacturer's instructio...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140100215
更新日期:2001-10-01 00:00:00
abstract::Alleles of the STR systems HumFES/FPS, HumVWA and HumD21S11 were sequenced and analyzed. Sequence data revealed 3 different systems concerning the complexity of their sequence structure. HumFES/FPS belongs to the STR polymorphism with a simple repeat structure. Only 2 subtypes were found with a base substitution in th...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF01224779
更新日期:1994-01-01 00:00:00
abstract::2-Amino-5-chloropyridine (ACP) is a degradation product of zopiclone (ZOP) and its two main metabolites N-desmethylzopiclone (NDZOP) and zopiclone N-oxide (ZOPNO). ACP may be formed when specimens are stored. ZOP instability in blood makes interpretation of concentrations difficult especially in cases of prolonged sam...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-014-1049-2
更新日期:2015-03-01 00:00:00
abstract::A method has been developed for the simultaneous determination of lysergic acid diethylamide (LSD), its epimer iso-LSD, and its main metabolites nor-LSD and 2-oxo-3-hydroxy LSD in blood, urine, and, for the first time, vitreous humor samples. The method is based on liquid/liquid extraction and liquid chromatography-mu...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-006-0078-x
更新日期:2007-07-01 00:00:00
abstract::Blood, saliva, and semen are some of the forensically most relevant biological stains commonly found at crime scenes, which can often be of small size or challenging due to advanced decay. In this context, it is of great importance to possess reliable knowledge about the effects of degradation under different environm...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-016-1373-9
更新日期:2016-11-01 00:00:00
abstract::The allele frequencies of DYS19 and DYS390 located on the Y chromosomes were determined from male bloodstain samples of 308 (DYS19) and 268 (DYS390) unrelated male adults in south-east Hungary. Six alleles could be distinguished in both systems, yielding 22 DYS19/DYS390 halotypes in a subset of 239 males. ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140050236
更新日期:1999-01-01 00:00:00
abstract::In three separate shooting incidents involving multiple gunshots, two FMJ bullets and one bullet fragment found at the scene (one from each case) were investigated for the presence of biological material from the victim after perforation. The surface of the missiles, which did not show obvious tissue traces when exami...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140050041
更新日期:1997-01-01 00:00:00
abstract::Abstract DNA typing of four tetrameric repeat loci (HUMVWA, HUMTH0I, D21SII and HPRT) was carried out in a Chinese Han population from Shanghai (East China) and one from Guangzhou (South-East China) using a quadruplex PCR amplification and detection of the fluorescent-labeled alleles on the ALF DNA sequencer. All loci...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140050187
更新日期:1998-01-01 00:00:00
abstract::Population genetic studies were carried out on 932 caucasians from Austria using the short tandem repeat system ACTBP2 (SEE33). A sequenced allelic ladder was used for typing (Möller et al. 1995). After native polyacrylamide gel electrophoresis all 26 alleles of the ladder were found as well as 194 alleles which migra...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140050111
更新日期:1998-01-01 00:00:00
abstract::Sexual assault is a complex situation with medical, psychological, and legal aspects. Forensic experts play a major role in terms of forensic and gynecological medical examination and evidence collection in order to maintain the chain of custody. Victims should be examined by a specially trained medico-legal examiner ...
journal_title:International journal of legal medicine
pub_type: 杂志文章,实务指引
doi:10.1007/s00414-018-1791-y
更新日期:2018-11-01 00:00:00
abstract::Drowning remains one of the major causes of death in most developed countries despite the fact that many of the victims are known to be at least moderate swimmers as well as healthy directly before the event. Here, fatal arrhythmias and especially the long QT syndrome (LQTS) have been proposed as the underlying mechan...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-015-1259-2
更新日期:2016-03-01 00:00:00
abstract::Sudden infant death syndrome (SIDS) is a multifactorial syndrome and assumingly, among other mechanisms, a deficit in respiratory control leads to a failure of arousal and autoresuscitation when the child is challenged by a stressful homeostatic event, e.g., hypoxia. We hypothesize that genetic polymorphisms involved ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-015-1232-0
更新日期:2015-09-01 00:00:00
abstract::We have analyzed 11 Y-STR loci (DYS19, the two DYS385 loci, DYS388, DYS389I/II, DYS390, DYS391, DYS392, DYS393, DXYS156Y) in 700 males from ten ethnic groups in east Asia in order to evaluate their usefulness for forensic and population genetic studies. A total of 644 different haplotypes were identified, among which ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-004-0518-4
更新日期:2005-07-01 00:00:00
abstract::We present a case of fatal intoxication by the application of a transdermal fentanyl patch upon a superficial bleeding abrasion of a 2-year-old girl. The grandmother discovered the body of the child in bed at approximately 7 a.m. External examination revealed a properly developed, nourished, and hydrated child, with s...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-015-1209-z
更新日期:2015-11-01 00:00:00