Y-chromosomal STR haplotypes and their applications to forensic and population studies in east Asia.

Abstract:

:We have analyzed 11 Y-STR loci (DYS19, the two DYS385 loci, DYS388, DYS389I/II, DYS390, DYS391, DYS392, DYS393, DXYS156Y) in 700 males from ten ethnic groups in east Asia in order to evaluate their usefulness for forensic and population genetic studies. A total of 644 different haplotypes were identified, among which 603 (86.14%) were individual-specific. The haplotype diversity averaged over all populations was 0.9997; using only the nine Y-STRs comprising the "minimal haplotype" (excluding DYS388 and DXYS156Y) it was 0.9996, a value similar to that found in 1924 samples from other Asian populations (0.9996; Lessig et al. Legal Medicine 5(2003) 160-163), and slightly higher than in European populations (0.9976; n=11,610; Roewer et al. For Sci International (2001) 118:103-111). All of the individual east Asian populations examined here had high haplotype diversity (> or =0.997), except for the Mongolians (0.992) and Manchurians (0.960). The most frequent haplotype identified by the nine markers was present at only 1% (7/700). Population comparisons based on Phi(ST) or rho genetic distance measures revealed clustering according to the traditional northeast-southeast distinction, but with exceptions. For example, the Yunnan population from southern China lay among the northern populations, possibly reflecting recent migration, while the Korean population, traditionally considered northern, lay at the boundary between northern and southern populations. An admixture estimate suggested 55(51-59)% northern, 45(41-49)% southern contribution to the Koreans, illustrating the complexity of the genetic history of this region.

journal_name

Int J Legal Med

authors

Kwak KD,Jin HJ,Shin DJ,Kim JM,Roewer L,Krawczak M,Tyler-Smith C,Kim W

doi

10.1007/s00414-004-0518-4

subject

Has Abstract

pub_date

2005-07-01 00:00:00

pages

195-201

issue

4

eissn

0937-9827

issn

1437-1596

journal_volume

119

pub_type

杂志文章
  • Fatal cerebellar haemorrhage due to phenprocoumon poisoning.

    abstract::A 32-year-old patient died of a cerebellar haemorrhage and the blood coagulation analysis before death suggested defective synthesis of vitamin K-dependent clotting factors due to vitamin K deficiency. The post-mortem toxicological examination of different tissues revealed phenprocoumon poisoning as the cause of death...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/BF01369825

    authors: Höhler T,Becker J,Meyer zum Büschenfelde KH,Rittner C

    更新日期:1996-01-01 00:00:00

  • Trajectory reconstruction from trace evidence on spent bullets. II. Are tissue deposits eliminated by subsequent impacts?

    abstract::STR-based individualisation of biological deposits on bullets after perforation of tissue, can identify the person injured or killed by a particular bullet and comparison with the firearms used can identify the weapon and thus possibly the person who did the shooting. In this study, the effect of subsequent impacts on...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s004140000203

    authors: Karger B,Stehmann B,Hohoff C,Brinkmann B

    更新日期:2001-01-01 00:00:00

  • Comparison of HPLC and CE for the analysis of dichlorprop in a case of intoxication.

    abstract::A 49-year-old white male was found lying unconscious at home. He had vomited, his mouth was filled with a white foam and a pungent odour filled the room. After emergency treatment blood, urine and stomach contents were screened for drugs after acid and alkaline extraction with subsequent derivatisation and GC-MS analy...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s004140050080

    authors: West A,Frost M,Köhler H

    更新日期:1997-01-01 00:00:00

  • Capillary zone electrophoresis and artificial neural networks for estimation of the post-mortem interval (PMI) using electrolytes measurements in human vitreous humour.

    abstract::Determination of electrolyte concentrations (mainly potassium) in vitreous humour has long been considered an important tool in human death investigations for the estimation of the post-mortem interval (PMI). On the basis of its well known potential in ion analysis, capillary zone electrophoresis (CZE) has recently be...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s004140100239

    authors: Bocaz-Beneventi G,Tagliaro F,Bortolotti F,Manetto G,Havel J

    更新日期:2002-02-01 00:00:00

  • Identifying novel microhaplotypes for ancestry inference.

    abstract::The use of DNA to determine the ancestry of an individual is becoming more and more important in the areas of forensics. Kidd et al. (Forensic Sci Int Genet 12:215-224, 2014) have been the first to identify and catalog haplotypes, termed as minihaplotypes (1-10-kilobase spans) and microhaplotypes (≤ 200 bp), with pote...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-018-1881-x

    authors: Chen P,Zhu W,Tong F,Pu Y,Yu Y,Huang S,Li Z,Zhang L,Liang W,Chen F

    更新日期:2019-07-01 00:00:00

  • The iliac crest in forensic age diagnostics: evaluation of the apophyseal ossification in conventional radiography.

    abstract::Due to the increasing significance of forensic age estimations in the age of globalisation, novel radiographic criteria besides clavicles and hand bones may provide additional certainty for forensic age expertises. The present study analyses the suitability of the iliac crest apophysis by means of 643 pelvic radiograp...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-012-0763-x

    authors: Wittschieber D,Vieth V,Domnick C,Pfeiffer H,Schmeling A

    更新日期:2013-03-01 00:00:00

  • Cardiac pathology in death from electrocution.

    abstract::To better characterize the morphologic changes in electrocution, morphologic changes in the hearts of 21 subjects, who died instantaneously of electrocution, were compared to the hearts of decedents with different types of death. Sixteen myocardial samples per heart were processed for histological examination, and sec...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-005-0011-8

    authors: Fineschi V,Karch SB,D'Errico S,Pomara C,Riezzo I,Turillazzi E

    更新日期:2006-03-01 00:00:00

  • An unusual observation of tetragametic chimerism: forensic aspects.

    abstract::A 41-year-old healthy Caucasian male showed an unidentifiable direct AB0 group and a B group by an indirect method revealing the presence of natural antibodies anti-A1 and anti-A2. Mixed fields with anti-B and anti-A+B antisera led to the conclusion that blood group B and 0 cell populations were present in a 1:1 ratio...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-009-0332-0

    authors: Verdiani S,Bonsignore A,Casarino L,Ferrari GM,Zia SC,De Stefano F

    更新日期:2009-09-01 00:00:00

  • Airbag contact in traffic accidents: DNA detection to determine the driver identity.

    abstract::A total of 34 deployed driver and passenger airbags from altogether 20 vehicles after frontal collisions were investigated. In 80% of the airbags possible biological traces could be located with an alternative light source (ALS, Polilight) at a wavelength of 450-470 nm. These traces were swabbed, a part of them additi...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-003-0406-3

    authors: Grubwieser P,Pavlic M,Günther M,Rabl W

    更新日期:2004-02-01 00:00:00

  • Analysis of linkage and linkage disequilibrium for syntenic STRs on 12 chromosomes.

    abstract::The purpose of this study is to evaluate allelic association and linkage of 18 adjacent syntenic short tandem repeat (STR) pairs form out of 30 markers located on 12 different autosomes. Linkage disequilibrium was tested by using the unknown gametic phase genotypes and phased haplotypes from 290 unrelated individuals ...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-014-1032-y

    authors: Wu W,Hao H,Liu Q,Han X,Wu Y,Cheng J,Lu D

    更新日期:2014-09-01 00:00:00

  • Individual identification of flood victims by DNA polymorphisms and autopsy findings.

    abstract::On September 23rd 1993 Genova was flooded by heavy rainstorms and 4 people disappeared, including an elderly couple. Four days later a partially skeletonized body was found floating near the coast. No visual identification was possible. Autopsy findings were consistent with the medical history of a possible victim. DN...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/BF01428409

    authors: Mannucci A,Casarino L,Bruni G,Lomi A,De Stefano F

    更新日期:1995-01-01 00:00:00

  • Statistical methods to assess the reliability of measurements in the procedures for forensic age estimation.

    abstract::In forensic science, anthropology, and archaeology, several techniques have been developed to estimate chronological age in both children and adults, using the relationship between age and morphological changes in the structure of teeth. Before implementing a statistical model to describe age as a function of the meas...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-009-0349-4

    authors: Ferrante L,Cameriere R

    更新日期:2009-07-01 00:00:00

  • Tumoural specimens for forensic purposes: comparison of genetic alterations in frozen and formalin-fixed paraffin-embedded tissues.

    abstract::In certain circumstances, tumour tissue specimens are the only DNA resource available for forensic DNA analysis. However, cancer tissues can show microsatellite instability and loss of heterozygosity which, if concerning the short tandem repeats (STRs) used in the forensic field, can cause misinterpretation of the res...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-010-0443-7

    authors: Ananian V,Tozzo P,Ponzano E,Nitti D,Rodriguez D,Caenazzo L

    更新日期:2011-05-01 00:00:00

  • VWA STR genotyping: further inconsistencies between Perkin-Elmer and Promega kits.

    abstract::We report a simultaneous study of the VWA STR locus by the Perkin-Elmer Profiler Plus kit and the Promega GenePrint CTTv kit in a population sample from North Portugal and in 418 meiosis from family material and paternity cases. PCR amplification and genotyping were performed according to the manufacturer's instructio...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s004140100215

    authors: Alves C,Amorim A,Gusmão L,Pereira L

    更新日期:2001-10-01 00:00:00

  • Dental age estimation in Somali children using the Willems et al. model.

    abstract:AIM:The aim of the current study was to retrospectively collect dental panoramic radiographs from Somali children living in Finland, to use the radiographic data to develop a new age estimation model based on the model established by Willems et al. (J Forensic Sci 46(4):893-895, 2001), and to compare the age prediction...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-018-1926-1

    authors: Metsäniitty M,Waltimo-Sirén J,Ranta H,Fieuws S,Thevissen P

    更新日期:2018-11-01 00:00:00

  • Cuts to the offender's own hand--unintentional self-infliction in the course of knife attacks.

    abstract::In a knife attack the perpetrator can unintentionally injure his own hand, if the knife does not have an adequate handguard and the tip of the blade hits a solid, mostly bony structure while being violently thrust into the victim's body. The injuries occurring under these conditions are localized on the flexor side of...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-004-0491-y

    authors: Schmidt U,Faller-Marquardt M,Tatschner T,Walter K,Pollak S

    更新日期:2004-12-01 00:00:00

  • Dental age estimation: periodontal ligament visibility (PLV)-pattern recognition of a conclusive mandibular maturity marker related to the lower left third molar at the 18-year threshold.

    abstract::The purpose of this study was to explore the applicability of periodontal ligament visibility (PLV) at the 18-year threshold. This mandibular maturity marker is graded into four separate age related stages, PLV-A, PLV-B, PLV-C, and PLV-D. These are discernible on a dental panoramic tomograph (DPT). The sample comprise...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-016-1468-3

    authors: Lucas VS,McDonald F,Andiappan M,Roberts G

    更新日期:2017-05-01 00:00:00

  • DNA typing of cellular material on perforating bullets.

    abstract::DNA typing of cellular debris from perforating bullets was investigated following shooting experiments. A total of 14 perforating gunshots were fired into 9 calves. PCR typing of tissue fragments was done using bovine-specific primers flanking a 247 bp segment within the bovine lactoglobulin gene. Positive amplificati...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/BF01369787

    authors: Karger B,Meyer E,Knudsen PJ,Brinkmann B

    更新日期:1996-01-01 00:00:00

  • Evaluation of the radiographic visibility of the root pulp in the lower third molars for the purpose of forensic age estimation in living individuals.

    abstract::The question of whether an individual has reached the age of 18 is of crucial importance in forensic age estimation practice. In some countries, the age threshold of 21 years is relevant as well. A completed mineralization of third molars is not a sufficient criterion for a diagnosis of a minimum age of 18 years with ...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-009-0415-y

    authors: Olze A,Solheim T,Schulz R,Kupfer M,Schmeling A

    更新日期:2010-05-01 00:00:00

  • Sudden infant death syndrome caused by cardiac arrhythmias: only a matter of genes encoding ion channels?

    abstract::Sudden infant death syndrome is the unexpected demise of a child younger than 1 year of age which remains unexplained after a complete autopsy investigation. Usually, it occurs during sleep, in males, and during the first 12 weeks of life. The pathophysiological mechanism underlying the death is unknown, and the letha...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s00414-016-1330-7

    authors: Sarquella-Brugada G,Campuzano O,Cesar S,Iglesias A,Fernandez A,Brugada J,Brugada R

    更新日期:2016-03-01 00:00:00

  • Humeral development from neonatal period to skeletal maturity--application in age and sex assessment.

    abstract::The goal of the present study is to examine cross-sectional information on the growth of the humerus based on the analysis of four measurements, namely, diaphyseal length, transversal diameter of the proximal (metaphyseal) end of the shaft, epicondylar breadth and vertical diameter of the head. This analysis was perfo...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-012-0713-7

    authors: Rissech C,López-Costas O,Turbón D

    更新日期:2013-01-01 00:00:00

  • Analysis of Y chromosome STR haplotypes in the European part of Russia reveals high diversities but non-significant genetic distances between populations.

    abstract::A total of 17 Y-specific STR loci were studied in 12 districts of the European part of Russia aiming to ascertain the amount of substructure required for the construction of a representative regional database. All groups exhibited high haplotype diversities but low inter-population variance as measured by an analysis ...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-007-0222-2

    authors: Roewer L,Willuweit S,Krüger C,Nagy M,Rychkov S,Morozowa I,Naumova O,Schneider Y,Zhukova O,Stoneking M,Nasidze I

    更新日期:2008-05-01 00:00:00

  • Evaluation of chronological age based on third molar development in the Spanish population.

    abstract::A cross-sectional study was carried out to assess chronological age estimation based on the stages of third lower molar development, following the eight stages (A-H) method of Demirjian et al. The final sample consisted of 1,054 orthopantomograms from Spanish individuals of known chronological age (range 14-21 years) ...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-005-0530-3

    authors: Prieto JL,Barbería E,Ortega R,Magaña C

    更新日期:2005-11-01 00:00:00

  • Investigation of phase II metabolism of 11-hydroxy-Δ-9-tetrahydrocannabinol and metabolite verification by chemical synthesis of 11-hydroxy-Δ-9-tetrahydrocannabinol-glucuronide.

    abstract::(-)-Δ-9-tetrahydrocannabinol ((-)-Δ-9-THC) is the main psychoactive constituent in cannabis. During phase I metabolism, it is metabolized to (-)-11-hydroxy-Δ-9-tetrahydrocannabinol ((-)-11-OH-Δ-9-THC), which is psychoactive, and to (-)-11-nor-9-carboxy-Δ-9-tetrahydrocannabinol ((-)-Δ-9-THC-COOH), which is psychoinacti...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-020-02387-w

    authors: Hassenberg C,Clausen F,Hoffmann G,Studer A,Schürenkamp J

    更新日期:2020-11-01 00:00:00

  • Amniotic fluid aspiration in cases of SIDS.

    abstract::The scope of this study was to evaluate the incidence and the eventual consequences of amniotic fluid aspiration (AFA) in cases of sudden infant death. Cases of sudden infant death syndrome (SIDS; n = 113: 39 females, 74 males; mean age 4.6 months) were compared to a control group of 39 cases of explained death (14 fe...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-009-0384-1

    authors: Fracasso T,Karger B,Vennemann M,Bajanowski T,Golla-Schindler UM,Pfeiffer H

    更新日期:2010-03-01 00:00:00

  • Stability of upper face sexual dimorphism in central European populations (Czech Republic) during the modern age.

    abstract::One of the most fundamental issues in forensic anthropology is the determination of sex and population affinity based on various skeletal elements. Therefore, we compared the sexual dimorphism of the upper facial skeleton from a recent Czech population (twenty-first century) with that of a population from Early Modern...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-017-1625-3

    authors: Bejdová Š,Dupej J,Krajíček V,Velemínská J,Velemínský P

    更新日期:2018-01-01 00:00:00

  • The potential of bone disease for personal identification: a case of tuberculosis.

    abstract::In the forensic anthropology practice, bone diseases are rarely considered for personal identification. In this paper, we present a forensic skeletonized case with tuberculous bone lesions, for which bone pathology may provide an indicator for positive personal identification. Antemortem hospital records were availabl...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-020-02348-3

    authors: Martrille L,De Angelis D,Blum A,Gauchotte G,Cattaneo C,Biehler-Gomez L

    更新日期:2020-09-01 00:00:00

  • Application of the method of Kvaal et al. to digital orthopantomograms.

    abstract::Estimation of age in individuals has received considerable attention in the forensic literature. The reduction of size of dental pulp cavity as a result of secondary dentin deposit with increasing age could be used as an indicator of age. This regression change, apart from morphological techniques, can also be analyse...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-008-0268-9

    authors: Landa MI,Garamendi PM,Botella MC,Alemán I

    更新日期:2009-03-01 00:00:00

  • Lactate dehydrogenase isoenzyme patterns in vaginal injury of a 4-year-old girl.

    abstract::Lactate dehydrogenase isoenzyme patterns indicative of vaginal injury were identified in extracts of a bloodstain on a pair of knickers belonging to a 4-year-old girl. No evidence of semen or saliva was detected in the stain. The result corroborated the clinical findings and provided strong evidence of child sexual ab...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/BF01625173

    authors: Harbison SA

    更新日期:1992-01-01 00:00:00

  • Antibody-mediated clean-up of blood for simultaneous HPLC determination of morphine and morphine glucuronides.

    abstract::For the interpretation of the concentration of morphine in blood samples of heroin consumers information about the concentration of the analgesic active morphine metabolite morphine-6-glucuronide is very important. Thus a simple but specific clean-up procedure based on immuno-affinity chromatography is presented for t...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s004140050073

    authors: Beike J,Köhler H,Blaschke G

    更新日期:1997-01-01 00:00:00