Comparison of HPLC and CE for the analysis of dichlorprop in a case of intoxication.

Abstract:

:A 49-year-old white male was found lying unconscious at home. He had vomited, his mouth was filled with a white foam and a pungent odour filled the room. After emergency treatment blood, urine and stomach contents were screened for drugs after acid and alkaline extraction with subsequent derivatisation and GC-MS analysis. Large quantites of 2,4-dichlorophenoxypropionic acid (dichlorprop, 2,4-DP) were found in all acid extracts. The man died 3 h later in hospital. Body fluids and tissues obtained at autopsy were analysed for 2,4-DP by high-performance liquid chromatography and capillary electrophoresis. The concentrations of 2,4-DP in cardiac blood, stomach contents, bile, liver, spleen, kidney and brain found by both methods were very similar.

journal_name

Int J Legal Med

authors

West A,Frost M,Köhler H

doi

10.1007/s004140050080

subject

Has Abstract

pub_date

1997-01-01 00:00:00

pages

251-3

issue

5

eissn

0937-9827

issn

1437-1596

journal_volume

110

pub_type

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