Abstract:
:A 49-year-old white male was found lying unconscious at home. He had vomited, his mouth was filled with a white foam and a pungent odour filled the room. After emergency treatment blood, urine and stomach contents were screened for drugs after acid and alkaline extraction with subsequent derivatisation and GC-MS analysis. Large quantites of 2,4-dichlorophenoxypropionic acid (dichlorprop, 2,4-DP) were found in all acid extracts. The man died 3 h later in hospital. Body fluids and tissues obtained at autopsy were analysed for 2,4-DP by high-performance liquid chromatography and capillary electrophoresis. The concentrations of 2,4-DP in cardiac blood, stomach contents, bile, liver, spleen, kidney and brain found by both methods were very similar.
journal_name
Int J Legal Medjournal_title
International journal of legal medicineauthors
West A,Frost M,Köhler Hdoi
10.1007/s004140050080subject
Has Abstractpub_date
1997-01-01 00:00:00pages
251-3issue
5eissn
0937-9827issn
1437-1596journal_volume
110pub_type
杂志文章abstract::We report about the case of a sudden unexpected death of a 25-year-old male suffering from infectious disease. An autopsy was ordered with no final premortem diagnosis. Microscopic and microbiological examination revealed a pneumococcal bronchopneumonia and hemophagocytic lesions in the bone marrow. After integrating ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-015-1305-0
更新日期:2016-05-01 00:00:00
abstract::Sex estimation is a task of utmost importance in forensic anthropology and bioarcheology. Along with the pelvic bone, the skull is the most important source of sexual dimorphism. On the human skull, the upper third of the face (i.e., the frontal bone) is one of the most significant sexually dimorphic structures useful...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-019-02063-8
更新日期:2019-07-01 00:00:00
abstract::The population origin of an individual is often requested to be determined from specimens left at a crime scene for identifying a suspect and individual identity. The melanocortin 1 receptor gene (MC1R) and P gene are associated with human pigmentation. Although several studies have reported that these genes are highl...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-008-0289-4
更新日期:2009-05-01 00:00:00
abstract::The present study aimed to evaluate the accuracy of mandibular measurements for sex determination in a Brazilian population. The sample was composed of 100 mandibles, of which 53 were female and 47 were male, and the average age was 57.03 years. The mandible measurement protocol was composed of 15 measurements, of whi...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-017-1681-8
更新日期:2018-05-01 00:00:00
abstract::Inferring an unknown DNA's ancestry using a set of ancestry-informative single nucleotide polymorphisms (SNPs) in forensic science is useful to provide investigative leads. This is especially true when there is no DNA database match or specified suspect. Thus, a set of SNPs with highly robust and balanced differential...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-018-1863-z
更新日期:2019-07-01 00:00:00
abstract::Despite being a common form of abuse, there is a paucity of literature describing shackling and wrist restraint injuries among survivors of torture. Forensic evaluation of alleged wrist restraint/handcuff injuries in survivors of torture presents challenges to the evaluator, especially if the injuries are remote and d...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-020-02451-5
更新日期:2021-01-07 00:00:00
abstract::In the last decade, increasing knowledge of epigenetics has led to the development of DNA methylation-based models to predict age, which have shown high predictive accuracy. However, despite the value of teeth as forensic samples, few studies have focused on this source of DNA. This study used bisulfite pyrosequencing...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-019-02242-7
更新日期:2020-03-01 00:00:00
abstract:PURPOSE:We investigated the incidence and distribution of post-mortem gas detected with multidetector computed tomography (MDCT) to identify factors that could distinguish artifactual gas from cardiac air embolism. MATERIAL AND METHODS:MDCT data of 119 cadavers were retrospectively examined. Gas was semiquantitatively...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-010-0542-5
更新日期:2012-01-01 00:00:00
abstract::We present a duo paternity test case to assess the biological relationship between a woman and her female child. After analyzing 57 autosomal and 19 X-chromosomal short tandem repeat loci, mother-daughter exclusions were discovered at four loci, which were all located on chromosome 2. Further testing of whole-genome s...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-018-1857-x
更新日期:2019-07-01 00:00:00
abstract::In this study, the effect of sample purification on total signal intensities of samples amplified with genRES MPX-2 (nine-locus multiplex) prior to capillary electrophoretic analysis has been investigated. Sample purification with the Qiaquick PCR purification kit led to an increase of the relative fluorescent signal ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-001-0277-4
更新日期:2002-06-01 00:00:00
abstract::Allele frequencies of the Short tandem repeat systems HumVWA and HumACTBP2 were determined from 105 unrelated individuals from the area of Szeged, Hungary. A total of 8 alleles was detected for VWA, and 23 alleles were found for ACTBP2. In both systems no deviations from Hardy-Weinberg equilibrium were observed. A com...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF02432127
更新日期:1996-01-01 00:00:00
abstract::Pharyngeal smears and paraffin-embedded tissue specimens (skeletal muscle, kidney) obtained from 10 male and 10 female individuals were evaluated using non-isotopic in situ hybridization (NISH) with commercial X- and Y-specific biotinylated probes which recognize the pericentromeric regions DXZ1 and DYZ1/DYZ3 of the X...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF01225497
更新日期:1994-01-01 00:00:00
abstract::We present the case of a 3.5-year-old boy with sudden anal blood loss at school. Sexual abuse was suspected, and, apart from anal fissures seen on sigmoidoscopy, no other clinical signs of any sort of disorder were present. As no medical explanation for the blood loss could be given, penetrating anal trauma was sugges...
journal_title:International journal of legal medicine
pub_type: 杂志文章,评审
doi:10.1007/s00414-005-0053-y
更新日期:2007-01-01 00:00:00
abstract::Sexual assault is a complex situation with medical, psychological, and legal aspects. Forensic experts play a major role in terms of forensic and gynecological medical examination and evidence collection in order to maintain the chain of custody. Victims should be examined by a specially trained medico-legal examiner ...
journal_title:International journal of legal medicine
pub_type: 杂志文章,实务指引
doi:10.1007/s00414-018-1791-y
更新日期:2018-11-01 00:00:00
abstract::In sauna-associated deaths, the vitality of heat exposure is of great importance. Two case reports address this. First, we present the case of a 77-year-old man who was found dead in the sauna of his family home. When found, the sauna door was closed, and the sauna indicated a temperature of 78 °C. The body had alread...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-021-02504-3
更新日期:2021-01-14 00:00:00
abstract::The Ion AmpliSeq™ HID single nucleotide polymorphism (SNP) panel, a primer pool of 103 autosomal SNPs and 33 Y-SNPs, was evaluated using the Ion 314™ Chip on the Ion PGM™ Sequencer with four DNA samples. The study focused on the sequencing of DNA at three different initial target quantities, related interpretation iss...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-013-0879-7
更新日期:2013-11-01 00:00:00
abstract:BACKGROUND:Postmortem interrogation of cardiac implantable electrical devices (CIED) in autopsy is not routinely performed. Thus, it remains unclear whether an interrogation might clarify time and cause of death. METHODS:Seventy of 4401 patients (1.6%) undergoing autopsy in 2014 and 2015 presented with a CIED. The exp...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-018-1932-3
更新日期:2019-05-01 00:00:00
abstract::The first aim of this study was to assess the diagnostic performance of presepsin (sCD14-ST) in postmortem serum from femoral blood compared to procalcitonin (PCT) to detect sepsis-related fatalities. The second aim was to compare sCD14-ST levels found in postmortem serum to the values in pericardial fluid to investig...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-012-0804-5
更新日期:2013-07-01 00:00:00
abstract::Hereditary hemochromatosis (HH) is a frequent autosomal recessive disease which causes iron-overload of various organs. Of all northern European affected individuals, 90-95% show 1 of 3 known point mutations in the HFE gene. Symptoms and organs involved can vary considerably: Only a small fraction of the 200,000-400,0...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-004-0451-6
更新日期:2004-06-01 00:00:00
abstract::The case concerns the sudden death of a 21-year-old male during a soccer game. The autopsy revealed large, calcified saccular aneurysms at the origins of both the left anterior descending and the right coronary arteries. Histologically, the wall of the aneurysms was thin and composed of an internal fibro-calcified lay...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140050213
更新日期:1999-01-01 00:00:00
abstract::Blood, saliva, and semen are some of the forensically most relevant biological stains commonly found at crime scenes, which can often be of small size or challenging due to advanced decay. In this context, it is of great importance to possess reliable knowledge about the effects of degradation under different environm...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-016-1373-9
更新日期:2016-11-01 00:00:00
abstract::The analysis of body fluids is of utmost importance in forensic casework since many biological fluids contain DNA. The ATR FT-IR spectroscopy is an emerging approach for the confirmatory, rapid, facile, non-destructive, and on-site identification and differentiation of body fluid stains. Notwithstanding the ATR FT-IR ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-020-02333-w
更新日期:2020-09-01 00:00:00
abstract::In the immigration case cited by Jeffreys et al. (1985), the biostatistical evaluation of blood group findings in 16 systems and of HLA-A,B findings for the mother and child, using a special kinship algorithm developed by Ihm and Hummel (1975), produced a probability of maternity of the Ghanaian-born putative mother o...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF01371238
更新日期:1992-01-01 00:00:00
abstract::When blood reaches an extracorporeal surface, a drying process is initiated. Properties of this drying process may be crucial for the correct assessment of case-specific time lapses, however, there is a lack of systematic studies concerning the drying times of blood. We present a study on drying properties of small bl...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-012-0734-2
更新日期:2012-09-01 00:00:00
abstract::Historically, radiographical identification has been done by comparing conventional antemortem and postmortem X-ray images. The advent of new technologies such as multislice computed tomography (MSCT) is making traditional antemortem examination increasingly less frequent. The authors present the results of MSCT study...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-007-0200-8
更新日期:2007-11-01 00:00:00
abstract:INTRODUCTION:The determination of age of majority (the 18-year-old threshold) using the popular Demirjian tooth staging method is unreliable, so other maturity markers are required. This study examines whether the Root Pulp Visibility (RPV) of the mandibular third molar is a useful indicator of age. METHODS:One thousa...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-019-02155-5
更新日期:2020-01-01 00:00:00
abstract::Bloodstained threads (1 cm in length) were tested to identify human origin by a direct ELISA-ABC method using biotinylated antibody against human HbA0. By this method human bloodstains were clearly distinguishable from bloodstains of other species including Japanese monkey. The minimum detection limit of bloodstains p...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF01369714
更新日期:1991-01-01 00:00:00
abstract::When a forensic DNA sample cannot be associated directly with a previously genotyped reference sample by standard short tandem repeat profiling, the investigation required for identifying perpetrators, victims, or missing persons can be both costly and time consuming. Here, we describe the outcome of a collaborative s...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-012-0788-1
更新日期:2013-05-01 00:00:00
abstract::Many studies related to three-dimensional facial reconstruction have been previously reported. On the other hand, no extensive work has been found in the literature about hand reconstruction as an identification method. In this paper, the feasibility of virtual reconstruction of hand skin based on (1) its skeleton and...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-007-0204-4
更新日期:2007-11-01 00:00:00
abstract::Allele frequencies at the short tandem repeat (STR) loci HumACTBP2 and HumVWA were determined in 118 unrelated individuals from Northern Italy (Milan area). For locus HumACTBP2 (SE33) a total of 39 alleles was observed. Furthermore, two interalleles (N18m+N19m) and one allele (> N35) were found which were not observed...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140050090
更新日期:1997-01-01 00:00:00