Abstract：
:Determination of electrolyte concentrations (mainly potassium) in vitreous humour has long been considered an important tool in human death investigations for the estimation of the post-mortem interval (PMI). On the basis of its well known potential in ion analysis, capillary zone electrophoresis (CZE) has recently been applied to achieve a rapid and simultaneous determination of inorganic ions in this extracellular fluid. In the present work, artificial neural networks (ANN) were applied for modelling of the relationship of multicomponent CZE analysis of K+, NH4+, Na+, and Ba2+ ions in vitreous humour with PMI. In a study based on 61 cases with different causes of death and a known PMI ranging from 3 to 144 h, the use of ANNs considering all inorganic ion data from the human vitreous humour, achieved a substantial improvement of post-mortem interval prediction. Good linear correlation was observed (r2 = 0.98) and in comparison to the traditional linear least squares (LLS) method applied only to K+ levels in the vitreous humour, the prediction of PMI with ANN was improved by a factor of 5 from approximately +/- 15 h to less than 3 h.
journal_name
Int J Legal Medjournal_title
International journal of legal medicineauthors
Bocaz-Beneventi G,Tagliaro F,Bortolotti F,Manetto G,Havel Jdoi
10.1007/s004140100239subject
Has Abstractpub_date
2002-02-01 00:00:00pages
5-11issue
1eissn
0937-9827issn
1437-1596journal_volume
116pub_type
杂志文章abstract：:Severe cold stress has been shown to cause changes in the expression and secretion of thrombomodulin (TM), an endothelial protein regulating haemostasis and inflammation. To further evaluate TM as a cold stress indicator, relative TM mRNA and TM protein levels in the myocardium and the concentrations of TM in serum an...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-014-1138-2
更新日期：2015-03-01 00:00:00
abstract：:Isopropyl alcohol, or propan-2-ol (IPA), is found in numerous chemicals including alcohol-based hand rubs whose use has been recently widely extended to the general population since the onset of the COVID-19 pandemic. This widespread of IPA use could potentially, but not necessarily, be responsible for an increase in ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-020-02444-4
更新日期：2021-01-01 00:00:00
abstract：:The estimation of the minimum postmortem interval can be implemented by age estimation of corpse-associated primary colonizers such as the blow flies (Diptera: Calliphoridae). In cases where pupae represent the oldest stages found on a body, their age must be added to the duration of prepupal development to estimate t...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-013-0922-8
更新日期：2014-05-01 00:00:00
abstract：:We present a single case report illustrating the diagnostic role of multi-slice computed tomography (MSCT) in the investigation of suspicious child death where mechanical asphyxia is suspected. The case illustrates how radiological findings that may not be observable on conventional plain X-ray were identified by post...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-010-0438-4
更新日期：2010-11-01 00:00:00
abstract：:The use of DNA to determine the ancestry of an individual is becoming more and more important in the areas of forensics. Kidd et al. (Forensic Sci Int Genet 12:215-224, 2014) have been the first to identify and catalog haplotypes, termed as minihaplotypes (1-10-kilobase spans) and microhaplotypes (≤ 200 bp), with pote...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-018-1881-x
更新日期：2019-07-01 00:00:00
abstract：:Blood, saliva, and semen are some of the forensically most relevant biological stains commonly found at crime scenes, which can often be of small size or challenging due to advanced decay. In this context, it is of great importance to possess reliable knowledge about the effects of degradation under different environm...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-016-1373-9
更新日期：2016-11-01 00:00:00
abstract：:Thyroid hormones are sometimes used for purposes for which they are not approved. Reasons for off-label use can be overweight, prevailing depressive mood, or various somatic symptoms. Information about the intake of thyroid hormones in order to lose weight can be easily obtained from inappropriate/nonmedical websites....
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-010-0423-y
更新日期：2010-11-01 00:00:00
abstract：:An obese man (height, 178 cm; weight, 160 kg; body mass index, 50.5 kg/m2) with a history of recurrent ventricular tachycardia (VT), cardiomyopathy, coronary sclerosis, and insulin-resistant diabetes suffered a right femur fracture in a vehicular accident. His fracture was repaired the following day, but shortly after...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-016-1392-6
更新日期：2016-11-01 00:00:00
abstract：:Population studies on six short tandem repeat loci, HUMF13A01, HUMFXIIIB, HUMLIPOL, HUMTH01, HUMTPOX and HUMVWFA31 were carried out in a sample of unrelated Japanese individuals (n = 337-545) living in Gifu Prefecture (central region of Japan). Five alleles could be identified for HUMFXIIIB, six for HUMF13A01, HUMLIPO...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/BF01369599
更新日期：1996-01-01 00:00:00
abstract：:Allele frequencies and forensic statistics of 13 autosomal short tandem repeat loci were estimated in 56 unrelated Iranian individuals. Except for two loci which were monomorph, a total of 5-11 alleles at each locus were observed and altogether 94 alleles for all selected loci were found. Our results show that 11 out ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-016-1342-3
更新日期：2016-11-01 00:00:00
abstract：:DNA typing was carried out on epithelial cells which were transferred from the hands of the suspect onto the neck of the victim. In an experimental study 16 suspect-victim combinations were investigated for estimating the typing success. Alternatively to an attack against the neck, the upper arm was used for "strangul...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140050063
更新日期：1997-01-01 00:00:00
abstract：:A case report of a 25-year-old man who committed suicide by intravenous injection himself of an aqueous home-made castor bean extract is presented. The patient was hospitalized and treated symptomatically and was released at its own request fourth day after intoxication. The next day, the patient's condition deteriora...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-020-02340-x
更新日期：2020-11-01 00:00:00
abstract：:A population database was generated from 118 unrelated Caucasoid individuals living in Spain. Sequence polymorphisms of the mitochondrial DNA (mtDNA) control region, hypervariable regions I and II (HVRI and HVRII) were determined using the polymerase chain reaction (PCR) and direct sequencing. A total of 102 different...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140000158
更新日期：2000-01-01 00:00:00
abstract：:A cross-sectional study was carried out to assess chronological age estimation based on the stages of third lower molar development, following the eight stages (A-H) method of Demirjian et al. The final sample consisted of 1,054 orthopantomograms from Spanish individuals of known chronological age (range 14-21 years) ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-005-0530-3
更新日期：2005-11-01 00:00:00
abstract：:Dendritic cells (DCs) can essentially contribute to innate and adaptive immune system in various organs. A double-color immunofluorescence analysis was carried out with anti-CD11c and -HLA-DRα antibodies to detect DCs in 53 skin wounds (their postinfliction intervals: group I, 0-3 days; group II, 4-7 days; group III, ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-019-02185-z
更新日期：2020-03-01 00:00:00
abstract：:Blood species identification is an important challenge in forensic science. Conventional methods used for blood species analysis are destructive and associated with time-consuming sample preparation steps. Nuclear magnetic resonance (NMR) spectroscopy is known for its nondestructive properties and fast results. This r...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-016-1500-7
更新日期：2017-05-01 00:00:00
abstract：:Allele frequencies of the Short tandem repeat systems HumVWA and HumACTBP2 were determined from 105 unrelated individuals from the area of Szeged, Hungary. A total of 8 alleles was detected for VWA, and 23 alleles were found for ACTBP2. In both systems no deviations from Hardy-Weinberg equilibrium were observed. A com...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/BF02432127
更新日期：1996-01-01 00:00:00
abstract：:The present paper analyses the applicability of the clinically prevalent skeletal age determination method of Tanner and Whitehouse for forensic age estimation in living individuals. For this purpose, the hand X-rays from 48 boys and 44 girls aged 12-16 years were evaluated retrospectively. The minima and maxima, the ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-008-0237-3
更新日期：2008-07-01 00:00:00
abstract：:A study of the genetic variability in the Chueta (Majorcan Jews) and the Balearic (Majorca and Minorca Islands) populations was carried out using a multiplex system containing the nine tetrameric STRs D3S1358, vWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317 and D7S820. The Chueta population has remained isolated be...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004149900101
更新日期：2000-01-01 00:00:00
abstract：:Immunohistochemical investigation of the respiratory tract and lungs of 63 fire victims revealed a statistically significant enhanced expression of heat-shock protein 70 (Hsp70) in the epiglottis, the trachea, and the main and the peripheral bronchi compared with a control group. In the fire victims, a strong expressi...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-006-0105-y
更新日期：2006-11-01 00:00:00
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journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-016-1377-5
更新日期：2016-11-01 00:00:00
abstract：:Messenger RNA (mRNA) markers have been extensively investigated for the identification of forensically relevant body fluids and tissues based on their expression profiles among cell types. As products of the backsplicing of pre-mRNAs, circular RNAs (circRNAs) share exonic sequences with their linear counterparts. The ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-019-02027-y
更新日期：2019-09-01 00:00:00
abstract：INTRODUCTION:The impact of socioeconomic status (SES) on tooth mineralization has seldom been evaluated. This is important because SES can be used as a proxy for quantifying factors in the environmental that can impact mineralization but that can be difficult to measure directly, such as nutrition. OBJECTIVE:The objec...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-016-1476-3
更新日期：2017-01-01 00:00:00
abstract：:The unique case of a 50-year-old known alcoholic whose corpse was exhumed 27 years after death is reported. The man apparently committed suicide by hanging, but many years later the case was questioned and homicide-linked to a long-lasting serial killer case-was suspected. Thus, the corpse was exhumed, and at the auto...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-008-0273-z
更新日期：2008-11-01 00:00:00
abstract：:An accurate and precise documentation of injuries is fundamental in a forensic pathological context. Photographs and manual measurements are taken of all injuries during autopsies, but ordinary photography projects a 3D wound on a 2D space. Using technologies such as photogrammetry, it is possible to create 3D detaile...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-016-1499-9
更新日期：2017-05-01 00:00:00
abstract：:It is difficult to carry out toxicological investigations in biological samples collected from extensively decomposed bodies and to interpret obtained results as several pitfalls should be considered: redistribution phenomena, degradation of xenobiotics during the postmortem period, contamination by putrefaction fluid...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-020-02267-3
更新日期：2020-07-01 00:00:00
abstract：:Brazilian population derives from Native Amerindians, Europeans, and Africans. Southeastern Brazil is the most populous region of the country. The present study intended to characterize the maternal genetic ancestry of 290 individuals from southeastern (Brazil) population. Thus, we made the sequencing of the three hyp...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-014-1023-z
更新日期：2014-07-01 00:00:00
abstract：:Stabbing with a kitchen knife is a common method of homicide in Europe. Serrated knives may leave tool markings (striations) in tissues. Documentation of striations is necessary for their use as forensic evidence. Traditional methods (physical casting and photography) have significant limitations, and micro-computed t...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-017-1715-2
更新日期：2018-03-01 00:00:00
abstract：:Immunohistochemistry is a well-established technique used in many research laboratories as well as in clinical diagnostics. The method allows to visualize the expression of proteins in biological tissues, as well as to evaluate this expression semi-quantitatively. For diagnosis, an optimal staining, based on a straigh...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-017-1575-9
更新日期：2017-11-01 00:00:00
abstract：:On September 23rd 1993 Genova was flooded by heavy rainstorms and 4 people disappeared, including an elderly couple. Four days later a partially skeletonized body was found floating near the coast. No visual identification was possible. Autopsy findings were consistent with the medical history of a possible victim. DN...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/BF01428409
更新日期：1995-01-01 00:00:00
