Abstract：
:The unique case of a 50-year-old known alcoholic whose corpse was exhumed 27 years after death is reported. The man apparently committed suicide by hanging, but many years later the case was questioned and homicide-linked to a long-lasting serial killer case-was suspected. Thus, the corpse was exhumed, and at the autopsy it was found to be naturally mummified. This fact permitted the analysis of body tissues with the aim to investigate the persistence of ethanol conjugates in the biological material 27 years after death. Fragments of liver and kidney, a blood clot, and a hair strand were collected and submitted to liquid chromatography tandem mass spectrometry analysis. Ethyl glucuronide (EtG) and ethyl sulfate (EtS) were identified and quantified in the liver, the kidney, and the blood clot. Hair analysis was found to be severely affected by ion suppression even after solid phase extraction. Consequently, EtG was identified in all hair segments (0-3 cm, 3-6 cm, and 6-10 cm), but no reliable quantification could be carried out. In summary, our findings demonstrate that, notwithstanding the expected conjugate degradation, EtG and EtS can be indicative of ante-mortem use of alcohol even many years after death.
journal_name
Int J Legal Medjournal_title
International journal of legal medicineauthors
Politi L,Morini L,Mari F,Groppi A,Bertol Edoi
10.1007/s00414-008-0273-zsubject
Has Abstractpub_date
2008-11-01 00:00:00pages
507-9issue
6eissn
0937-9827issn
1437-1596journal_volume
122pub_type
杂志文章abstract：:Sudden infant death syndrome (SIDS) is a multifactorial syndrome and assumingly, among other mechanisms, a deficit in respiratory control leads to a failure of arousal and autoresuscitation when the child is challenged by a stressful homeostatic event, e.g., hypoxia. We hypothesize that genetic polymorphisms involved ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
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更新日期：2015-09-01 00:00:00
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journal_title：International journal of legal medicine
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journal_title：International journal of legal medicine
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journal_title：International journal of legal medicine
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journal_title：International journal of legal medicine
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journal_title：International journal of legal medicine
pub_type： 杂志文章
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pub_type： 杂志文章
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journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-017-1620-8
更新日期：2017-09-01 00:00:00
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journal_title：International journal of legal medicine
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更新日期：2009-09-01 00:00:00
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pub_type： 杂志文章
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更新日期：2018-05-01 00:00:00
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journal_title：International journal of legal medicine
pub_type： 杂志文章,多中心研究
doi：10.1007/BF01225414
更新日期：1994-01-01 00:00:00
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更新日期：2013-01-01 00:00:00
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journal_title：International journal of legal medicine
pub_type： 杂志文章
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更新日期：2018-03-01 00:00:00
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journal_title：International journal of legal medicine
pub_type： 杂志文章
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更新日期：2002-02-01 00:00:00
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journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-014-0967-3
更新日期：2014-05-01 00:00:00
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journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-006-0078-x
更新日期：2007-07-01 00:00:00
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journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-006-0148-0
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pub_type： 杂志文章
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更新日期：1994-01-01 00:00:00
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journal_title：International journal of legal medicine
pub_type： 杂志文章,多中心研究
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journal_title：International journal of legal medicine
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journal_title：International journal of legal medicine
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journal_title：International journal of legal medicine
pub_type： 杂志文章
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