Abstract：
:The sudden infant death syndrome (SIDS) is at present based on unknown pathogenetical mechanisms but in industrial nations is the most common cause of death in infancy after the perinatal period. Studies of a large number of adrenal glands in this syndrome have not been reported. Therefore, we evaluated 146 SIDS cases (85 males, 61 females, aged 14-465 days) and 24 control cases (17 males, 7 females, aged 18-623 days) by light microscopy, morphometry and immunocytochemistry (anti-chromogranin A and anti-S100 protein). Our data revealed a normal maturation of the adrenal glands in SIDS cases. Necroses, extensive hemorrhages or inflammation were not found. A focal lipid depletion of the zona fasciculata was seen in 92% of the adrenal glands of the SIDS and control cases. We found a siderosis (in 33% of the SIDS cases and 4% of the control cases) and calcium deposits (13% and 12% respectively) due to hyperemic involution of the fetal zone. The medulla, including the sustentacular cells (S 100 protein-positive cells) and chromaffin cells (chromogranin A-positive cells) was unchanged. Our results indicate that the few morphological alterations of the adrenal glands in SIDS cases are the effect of the underlying disease and not the cause of the sudden death.
journal_name
Int J Legal Medjournal_title
International journal of legal medicineauthors
Pérez-Platz U,Saeger W,Dhom G,Bajanowski Tdoi
10.1007/BF01225413subject
Has Abstractpub_date
1994-01-01 00:00:00pages
244-8issue
5eissn
0937-9827issn
1437-1596journal_volume
106pub_type
杂志文章,多中心研究abstract：:This paper considers the statistical evaluation of DNA mixtures in the following situations: (1) two unknown contributors are related respectively to two typed persons, (2) two of the unknown or untyped contributors are related and the third unknown contributor is related to a typed person, or (3) there are two pairs ...
journal_title：International journal of legal medicine
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journal_title：International journal of legal medicine
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journal_title：International journal of legal medicine
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journal_title：International journal of legal medicine
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journal_title：International journal of legal medicine
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journal_title：International journal of legal medicine
pub_type： 杂志文章
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journal_title：International journal of legal medicine
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journal_title：International journal of legal medicine
pub_type： 杂志文章,评审
doi：10.1007/BF01369676
更新日期：1996-01-01 00:00:00
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journal_title：International journal of legal medicine
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journal_title：International journal of legal medicine
pub_type： 杂志文章
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更新日期：2009-03-01 00:00:00
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journal_title：International journal of legal medicine
pub_type： 杂志文章
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更新日期：2015-01-01 00:00:00
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journal_title：International journal of legal medicine
pub_type： 杂志文章
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journal_title：International journal of legal medicine
pub_type： 杂志文章
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journal_title：International journal of legal medicine
pub_type： 杂志文章
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journal_title：International journal of legal medicine
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journal_title：International journal of legal medicine
pub_type： 杂志文章
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更新日期：1997-01-01 00:00:00
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journal_title：International journal of legal medicine
pub_type： 杂志文章
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更新日期：1996-01-01 00:00:00
abstract：PURPOSE:The response to traumatic brain injury (TBI) is complex and induces various biological pathways in all brain regions that contribute to bad outcomes. The cerebellar hypoxia after a frontal cortex injury may potentiate the pathophysiological impacts of TBI. Therefore, a gene expression analysis was conducted to ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
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更新日期：2015-07-01 00:00:00
