Population data and phylogenetic structure of Han population from Jiangsu province of China on GlobalFiler STR loci.

Abstract:

:Forensic statistical parameters based on allelic frequencies of commonly used short tandem repeats were estimated for the Han population of Jiangsu province from P.R. China. The 6-dye GlobalFiler™ PCR amplification kit incorporates 21 autosomal STRs, providing reliable DNA typing results with enhanced the power of discrimination. Here, we analyzed the GlobalFiler™ STR loci in 516 unrelated individuals from Jiangsu Han population. A total of 256 alleles were observed ranging between 5 and 35.2 repeat units, and SE33 showed the greatest power of discrimination (34 alleles) in Jiangsu Han population. Most of the loci were found to be in the Hardy-Weinberg equilibrium after the Bonferroni correction with the exception of D3S1358. The combined power of exclusion (CPE) was 0.999999996353609, and the combined match probability (CMP) was 3.64 × 10-25. Phylogenetic parameters including pairwise genetic distances showed that Han population living in Jiangsu had closest genetic relationship with other East Asian populations. The present study provides precise reference database for forensic applications and population genetic studies.

journal_name

Int J Legal Med

authors

Adnan A,Zhan X,Kasim K,Rakha A,Xin XJ

doi

10.1007/s00414-018-1815-7

subject

Has Abstract

pub_date

2018-09-01 00:00:00

pages

1301-1304

issue

5

eissn

0937-9827

issn

1437-1596

pii

10.1007/s00414-018-1815-7

journal_volume

132

pub_type

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