Abstract：
:Mitochondrial DNA (mtDNA) from 100 unrelated British White Caucasians was extracted, amplified and directly sequenced. Sequences of approximately 800 nucleotides were obtained from 2 hypervariable segments within the non-coding region of the mitochondrial genome. A total of 91 different sequences were observed with an average nucleotide diversity of 1.1%. The most diverse pair of sequences differed at 3.6% of their nucleotide (nt) sites. Comparison to a consensus reference sequence showed that each region was polymorphic to a similar extent. Different methods of genetic analysis were used to examine the variation in each region, including pairwise comparisons, which demonstrated that although the data did not fit a Poisson distribution, the fit was closer to a Negative Binomial distribution.
journal_name
Int J Legal Medjournal_title
International journal of legal medicineauthors
Piercy R,Sullivan KM,Benson N,Gill Pdoi
10.1007/BF01225046subject
Has Abstractpub_date
1993-01-01 00:00:00pages
85-90issue
2eissn
0937-9827issn
1437-1596journal_volume
106pub_type
杂志文章abstract：:A block of an injury instrument will be left in wounds sometimes, and the suspect instrument can be discriminated by comparison with the block that was left through elemental analysis. In this study, three brands (Shibazi, Zhangxiaoquan, Qiaoxifu) of kitchen knives with forged, chop, and slice application series were ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-013-0829-4
更新日期：2014-03-01 00:00:00
abstract：:Carisoprodol is commonly prescribed as a centrally acting muscle relaxant, but it is also subject to abuse. The literature describing fatal intoxications with the drug is limited to a relatively small number of cases, and there are inconsistencies with regard to which concentration levels that are toxic. We therefore ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-006-0139-1
更新日期：2007-09-01 00:00:00
abstract：:Single nucleotide polymorphism (SNP) typing offers promise to forensic genetics. Various strategies and panels for analyzing SNP markers for individual identification have been published. However, the best panels with fewer identity SNPs for all major population groups are still under discussion. This study aimed to f...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-015-1250-y
更新日期：2016-01-01 00:00:00
abstract：:Anthropologists are constantly seeking to improve methods for age estimation in the human skeleton. A new method was introduced about a decade ago that assesses the morphological changes that take place in the acetabulum as an individual ages. The pelvis is usually well preserved in forensic cases, which makes this me...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-015-1299-7
更新日期：2016-05-01 00:00:00
abstract：:DNA-based prediction for externally visible characteristics such as eye color is already a useful tool in forensic criminal investigations. The IrisPlex system, consisting of six single nucleotide polymorphisms (SNPs) and a prediction model, was developed based on individuals from several European populations. Other r...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-013-0953-1
更新日期：2014-05-01 00:00:00
abstract：PURPOSE:The aim of this multi-reader feasibility study was to evaluate new post-processing CT imaging tools in rib fracture assessment of forensic cases by analyzing detection time and diagnostic accuracy. MATERIALS AND METHODS:Thirty autopsy cases (20 with and 10 without rib fractures in autopsy) were randomly select...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-016-1412-6
更新日期：2017-03-01 00:00:00
abstract：:In the last decade, increasing knowledge of epigenetics has led to the development of DNA methylation-based models to predict age, which have shown high predictive accuracy. However, despite the value of teeth as forensic samples, few studies have focused on this source of DNA. This study used bisulfite pyrosequencing...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-019-02242-7
更新日期：2020-03-01 00:00:00
abstract：BACKGROUND:Postmortem interrogation of cardiac implantable electrical devices (CIED) in autopsy is not routinely performed. Thus, it remains unclear whether an interrogation might clarify time and cause of death. METHODS:Seventy of 4401 patients (1.6%) undergoing autopsy in 2014 and 2015 presented with a CIED. The exp...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-018-1932-3
更新日期：2019-05-01 00:00:00
abstract：:We present a duo paternity test case to assess the biological relationship between a woman and her female child. After analyzing 57 autosomal and 19 X-chromosomal short tandem repeat loci, mother-daughter exclusions were discovered at four loci, which were all located on chromosome 2. Further testing of whole-genome s...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-018-1857-x
更新日期：2019-07-01 00:00:00
abstract：:Determining the time of injury is an important but still a challenging task in forensic anthropology. In literature, many descriptions can be found to make a distinction between perimortem and postmortem fractures. Characteristics that are more related to fractures in fresh conditions, however, are not extensively inv...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-016-1514-1
更新日期：2017-05-01 00:00:00
abstract：:The authors report on a young boy who was bitten into his face by an unknown animal while being asleep in a tent. Given the bite marks and the location of the scene, members of the mustelidae and canidae families were the first "suspects." Deoxyribunucleic acid (DNA) recovered from the tent's wall was analyzed with re...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-012-0674-x
更新日期：2012-05-01 00:00:00
abstract：:Postmortem MRI (PMMR) examinations are seldom performed in legal medicine due to long examination times, unfamiliarity with the technique, and high costs. Furthermore, it is difficult to obtain access to an MRI device used for patients in clinical settings to image an entire human body. An alternative is available: ex...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-014-1058-1
更新日期：2015-05-01 00:00:00
abstract：:In a Japanese population study of the D1S80 locus 24 alleles ranging from allele 16 to allele43 were analysed using PCR-RFLP. As two repeat units were found to contain the restriction cleavage site (CCAGG) for EcoRII, we digested the alleles with EcoRII, separated the digested fragments on polyacrylamide gels and stai...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140050146
更新日期：1998-01-01 00:00:00
abstract：:The smoking cessation agent varenicline acts as a partial agonist on α(4)β(2) nicotinic acetylcholine receptors. Although debated, several reports have linked varenicline therapy to an increased risk of suicidal thoughts and/or suicide. In addition, several non-fatal overdose cases have been reported. In this report, ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-012-0695-5
更新日期：2013-01-01 00:00:00
abstract：:The use of phenethylamines in the dance scene is now well established. Apart from amphetamine, the commonest phenethylamine encountered in clinical and forensic settings is 3,4-methylenedioxymethamphetamine (MDMA) commonly known as ecstasy. Other phenethylamines, which have similar effects are encountered, such as 3,4...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140050291
更新日期：2000-01-01 00:00:00
abstract：:The histological staining technique using rhodizonate is also effective for the determination of the firing distance by examining the distribution and intensity of the staining reaction. The differentiation between absolute close-range shots and long-range shots is generally possible without any doubt. The method is n...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140100220
更新日期：2002-02-01 00:00:00
abstract：:The molecular composition of the genetic substrate recovered from seven aged forensic samples has been extensively investigated. A simple enzymatic test based on DNAseI incubation of the extracts showed that the UV-fluorescent material from the forensic specimens is composed of nucleic acids, with the DNA fraction rep...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-002-0326-7
更新日期：2002-12-01 00:00:00
abstract：:In clinical and forensic practice, fatal thromboembolism is a major problem, particularly in a patient with no pre-existing risk factors. Out of a recent case, we discuss here the criteria for age determination of venous thrombi in a 46-year-old female with concomitant deep vein thrombosis in the common femoral left v...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-017-1705-4
更新日期：2018-05-01 00:00:00
abstract：:In order to establish a reliable age indicator in the period when all other epiphyseal age indicators have already been inactivated, medial clavicle as the bone with the longest period of growth became the object of various investigations. However, the lack of population-specific method often made it unreliable in som...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-012-0791-6
更新日期：2013-05-01 00:00:00
abstract：:Identification of unknown bodies is mainly made by dental examination and comparison with accurate dental records. Therefore it is necessary to examine the jaws carefully and to locate every tooth-coloured dental restoration. Overlooking dental fillings can make positive identification impossible. The technique descri...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140050138
更新日期：1998-01-01 00:00:00
abstract：:Blank cartridge guns are generally regarded as being harmless and are not considered to be firearms in most countries. A comparison of the legal situations in Germany and Austria concerning weapons is given. There have been several reports of serious injuries and even fatalities due to these weapons. Ballistic experim...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140050156
更新日期：1998-01-01 00:00:00
abstract：:Six synthetic head models wearing ballistic protective helmets were used to recreate two military combat-related shooting incidents (three per incident, designated 'Incident 1' and 'Incident 2'). Data on the events including engagement distances, weapon and ammunition types was collated by the Defence Science and Tech...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-018-1802-z
更新日期：2019-01-01 00:00:00
abstract：:Evaluation of the radiographic visibility of root pulp in mandibular third molars has been suggested as an alternative method for estimation of legal age threshold in living individuals when the root apices are mature. Here, we assessed the accuracy of this method for age thresholds of 18 and 21 years. A sample of 463...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-019-02036-x
更新日期：2019-09-01 00:00:00
abstract：:As a contribution to the geographic coverage of EMPOP, currently the best available forensic mitochondrial DNA (mtDNA) database, a total of 299 Swedish individuals were analysed by sequencing of the first and second hypervariable regions of the mtDNA genome. In this sample set, a total of 179 different haplotypes were...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-013-0908-6
更新日期：2013-11-01 00:00:00
abstract：:Necrophagous blow fly larvae can provide accurate estimates of the minimum postmortem interval in death investigations. During larval development, predictable morphological changes occur and measurements of weight, length, and width are compared to species-specific growth curves for reliable age estimates. However, ag...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-012-0699-1
更新日期：2013-01-01 00:00:00
abstract：:2-Amino-5-chloropyridine (ACP) is a degradation product of zopiclone (ZOP) and its two main metabolites N-desmethylzopiclone (NDZOP) and zopiclone N-oxide (ZOPNO). ACP may be formed when specimens are stored. ZOP instability in blood makes interpretation of concentrations difficult especially in cases of prolonged sam...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-014-1049-2
更新日期：2015-03-01 00:00:00
abstract：:A system of nomenclature is proposed for the complex STR system ACTBP2 (SE33) in order to facilitate data exchange between laboratories. The nomenclature conforms to the ISFH recommendations as far as it is possible for such complex systems. A blind trial was carried out between up to 20 laboratories to ascertain the ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140050124
更新日期：1998-01-01 00:00:00
abstract：:The allelic frequency distributions and statistical forensic parameters of 26 mini short tandem repeat (mini-STR) loci in a sample of 1575 unrelated individuals from five different Brazilian regions were obtained. All the analyzed loci showed great diversity and were highly informative. The results were compared with ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-018-1777-9
更新日期：2018-09-01 00:00:00
abstract：:The aim of this paper is twofold: first, to evaluate an Indian sample by Cameriere's European formula; and second, if this formula turns out to be unsuitable, to study a specific formula for Indian children. Orthopantomographs taken from 480 Indian children (227 girls and 253 boys) aged between 3 and 15 years were ana...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-010-0427-7
更新日期：2010-05-01 00:00:00
abstract：:A cross-sectional study was carried out to assess chronological age estimation based on the stages of third lower molar development, following the eight stages (A-H) method of Demirjian et al. The final sample consisted of 1,054 orthopantomograms from Spanish individuals of known chronological age (range 14-21 years) ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-005-0530-3
更新日期：2005-11-01 00:00:00
