Abstract:
:The use of phenethylamines in the dance scene is now well established. Apart from amphetamine, the commonest phenethylamine encountered in clinical and forensic settings is 3,4-methylenedioxymethamphetamine (MDMA) commonly known as ecstasy. Other phenethylamines, which have similar effects are encountered, such as 3,4-methylenedioxyethylamphetamine (MDEA) and their use has resulted in death. We report two deaths associated with another less commonly encountered member of the group, N-methyl-1-(3,4-methylenedioxyphenyl)-2-butanamine (MBDB), also known as Methyl-J and Eden.
journal_name
Int J Legal Medjournal_title
International journal of legal medicineauthors
Carter N,Rutty GN,Milroy CM,Forrest ARdoi
10.1007/s004140050291subject
Has Abstractpub_date
2000-01-01 00:00:00pages
168-70issue
3eissn
0937-9827issn
1437-1596journal_volume
113pub_type
杂志文章abstract::Brazilian population derives from Native Amerindians, Europeans, and Africans. Southeastern Brazil is the most populous region of the country. The present study intended to characterize the maternal genetic ancestry of 290 individuals from southeastern (Brazil) population. Thus, we made the sequencing of the three hyp...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-014-1023-z
更新日期:2014-07-01 00:00:00
abstract::Sequence variation of the hypervariable segments (HVS) I/II of mitochondrial DNA (mtDNA) and the haplogroup affiliation were determined in a sample of 271 Italian subjects. This analysis showed that 42% of the individuals could be ascribed to H, the most frequent haplogroup in European Caucasian populations. This frac...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-005-0059-5
更新日期:2006-05-01 00:00:00
abstract::Sudden infant death syndrome is the unexpected demise of a child younger than 1 year of age which remains unexplained after a complete autopsy investigation. Usually, it occurs during sleep, in males, and during the first 12 weeks of life. The pathophysiological mechanism underlying the death is unknown, and the letha...
journal_title:International journal of legal medicine
pub_type: 杂志文章,评审
doi:10.1007/s00414-016-1330-7
更新日期:2016-03-01 00:00:00
abstract::The histological staining technique using rhodizonate is also effective for the determination of the firing distance by examining the distribution and intensity of the staining reaction. The differentiation between absolute close-range shots and long-range shots is generally possible without any doubt. The method is n...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140100220
更新日期:2002-02-01 00:00:00
abstract:AIM:The aim of the current study was to retrospectively collect dental panoramic radiographs from Somali children living in Finland, to use the radiographic data to develop a new age estimation model based on the model established by Willems et al. (J Forensic Sci 46(4):893-895, 2001), and to compare the age prediction...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-018-1926-1
更新日期:2018-11-01 00:00:00
abstract::P-glycoprotein (P-gp), encoded by the ABCB1/MDR1 gene, is a drug transporter at the blood-brain barrier. Several polymorphisms in the ABCB1 gene are known to affect the activity and/or expression of P-gp, thereby influencing the treatment response and toxicity of P-gp substrates like citalopram and venlafaxine. In thi...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-013-0849-0
更新日期:2013-05-01 00:00:00
abstract::Myocardial infarctions go along with biomechanical stress, i.e. stretching of muscle fibres, and the expression of certain marker molecules. We tested if two of those markers, endothelin-1 (ET-1) and growth differentiation factor 15 (GDF-15), can be used as immunohistochemical markers for myocardial ischaemia/infarcti...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-017-1726-z
更新日期:2018-03-01 00:00:00
abstract::We describe new primers for the detection of the STR polymorphism at the CSF1PO locus. These primers have been designed to produce shorter amplicons (150-182 bp) than the primers in standard use (295-327 bp). The reliability of the new primers for CSF1PO typing has been demonstrated by testing on known samples and by ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF02441025
更新日期:1997-01-01 00:00:00
abstract::Three immunohistochemically different myelomonocytic subtypes, i.e. MRP8, MRP14 and 27E10 were quantitatively evaluated in the intraalveolar, alveolar-interstitial and alveolar-intracapillary lung compartments. Lung sections from 5 major groups with defined causes of death, i.e. drowning and death during immersion (DI...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140050091
更新日期:1997-01-01 00:00:00
abstract::One of the most common conditions during fetal development is anencephaly, which often involves many identification difficulties in the context of physical anthropology, as it causes severe skull challenges. In this paper, we describe the alterations found in the skulls of two perinatal individuals with anencephaly fr...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-014-1123-9
更新日期:2015-07-01 00:00:00
abstract::Allele frequencies of the Short tandem repeat systems HumVWA and HumACTBP2 were determined from 105 unrelated individuals from the area of Szeged, Hungary. A total of 8 alleles was detected for VWA, and 23 alleles were found for ACTBP2. In both systems no deviations from Hardy-Weinberg equilibrium were observed. A com...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF02432127
更新日期:1996-01-01 00:00:00
abstract::We demonstrate the applicability of ion-pair reversed-phase high-performance liquid chromatography-electrospray ionization time-of-flight mass spectrometry (ICEMS) for the simultaneous characterization of length and nucleotide polymorphisms. Two sections within the first (HVS-I) and second (HVS-II) hypervariable segme...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-006-0117-7
更新日期:2007-01-01 00:00:00
abstract::Scars of human skin can on occasions provide a very useful ancillary method of identification of an unknown deceased. If the age of any visible scars can be estimated objectively, then this might be of some assistance in the identification procedure. Melanocytes migrate into scar tissue as it ages and their number wit...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140100225
更新日期:2001-10-01 00:00:00
abstract::Advances in forensic identification using molecular genetics are helpful in resolving some historical mysteries. The aim of this study was to confirm the authenticity of shrunken-head artifacts exhibited by two Polish museums. Shrunken heads, known as tsantsas, were headhunting trophies of South American Indians (Jiva...
journal_title:International journal of legal medicine
pub_type: 历史文章,杂志文章
doi:10.1007/s00414-016-1448-7
更新日期:2017-05-01 00:00:00
abstract::Age estimation in living individuals around the age of 18 years remains a difficult challenge. In this study, the anterior inferior vertebral ring apophysis development of cervical vertebrae C2, C3, and C4 of 496 white and 478 black South African individuals aged between 15 and 22 years was assessed from cephalometric...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-019-02137-7
更新日期:2019-11-01 00:00:00
abstract::This paper investigates the effects that different summary statistics (minimum, median, mean, or maximum), temporal sampling resolutions (duration between sampling events), and sample sizes (number of individuals sampled per sampling event) had on the accuracy and precision of the regression coefficients of a typical ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-008-0243-5
更新日期:2008-09-01 00:00:00
abstract::For the interpretation of the concentration of morphine in blood samples of heroin consumers information about the concentration of the analgesic active morphine metabolite morphine-6-glucuronide is very important. Thus a simple but specific clean-up procedure based on immuno-affinity chromatography is presented for t...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140050073
更新日期:1997-01-01 00:00:00
abstract::The Ion AmpliSeq™ HID single nucleotide polymorphism (SNP) panel, a primer pool of 103 autosomal SNPs and 33 Y-SNPs, was evaluated using the Ion 314™ Chip on the Ion PGM™ Sequencer with four DNA samples. The study focused on the sequencing of DNA at three different initial target quantities, related interpretation iss...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-013-0879-7
更新日期:2013-11-01 00:00:00
abstract::We have sequenced the entire mtDNA genome (mtGenome) of 241 individuals who match 1 of 18 common European Caucasian HV1/HV2 types, to identify sites that permit additional forensic discrimination. We found that over the entire mtGenome even individuals with the same HV1/HV2 type rarely match. Restricting attention to ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-004-0427-6
更新日期:2004-06-01 00:00:00
abstract::In this study the development of a 13-locus multiplex-PCR system fitting the updated demands for paternity testing in Germany is described. For this purpose an existing multiplex PCR system that allows the simultaneous amplification of eight different STR loci together with the sex-specific locus amelogenin ( genRESMP...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-003-0420-5
更新日期:2004-02-01 00:00:00
abstract::The performance of two detection techniques for body fluids, the Spectra-Physics(R) Revealtrade mark portable forensic laser system and the mercury-arc lamp Lumatec Superlite 400, was evaluated with various biological stains on different substrates. Serial dilutions of neat, 1/10, 1/100 and 1/1,000 using fluid semen, ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-007-0214-2
更新日期:2008-05-01 00:00:00
abstract::The level of exposure or concealment of a cadaver is known to have an important impact on insect colonisation and decomposition but has been the subject of few investigations. In the present study, 30 pig carcasses were stored in three different types of containers (suitcases, trashcans and drums) with different level...
journal_title:International journal of legal medicine
pub_type:
doi:10.1007/s00414-019-02089-y
更新日期:2019-09-01 00:00:00
abstract::Insertion-deletion (INDEL) markers are very frequent in the human genome and present several advantages for population and forensic studies, such as low mutation rates, easy interpretation, small amplicons, easy genotyping, and the possibility of using multiplex PCR. The great adaptability of INDELs for amplification ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-011-0588-z
更新日期:2012-07-01 00:00:00
abstract::To increase the reliability of forensic age estimations in living adolescents and young adults where there is no legitimation for X-ray examinations, it would be desirable to establish radiation-free imaging methods. In the present study, the ossification stage of the distal femoral epiphysis was determined retrospect...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-014-0967-3
更新日期:2014-05-01 00:00:00
abstract::Carisoprodol is commonly prescribed as a centrally acting muscle relaxant, but it is also subject to abuse. The literature describing fatal intoxications with the drug is limited to a relatively small number of cases, and there are inconsistencies with regard to which concentration levels that are toxic. We therefore ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-006-0139-1
更新日期:2007-09-01 00:00:00
abstract::Blunt force is a frequently used type of violence especially because it can be performed with basically every object of our daily lives or with bare hands or feet. The injuries and medical consequences have been widely examined, whereas the forces and especially the energies acting on impact have rarely been analyzed....
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-017-1689-0
更新日期:2018-01-01 00:00:00
abstract::To investigate the genetic variation and forensic efficiency of 19 X-STR loci in the Zhuang and Mulao minorities, we calculated allele frequencies, forensic parameters, and haplotype frequencies of 405 Zhuang and 234 Mulao unrelated healthy individuals from Guangxi Zhuang Autonomous Region of China. Furthermore, we an...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-019-02004-5
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND:As sex estimation is an important step to delineate the biological profile, the development of tools employing anatomical structures which may maintain their integrity even after extreme events, such as the maxillary sinus, become useful for forensic identification. Thus, the aim in the present study was to ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-018-1869-6
更新日期:2019-07-01 00:00:00
abstract::We developed two multiplex systems for the coamplification of X-chromosomal short tandem repeats (STRs). X-Multiplex 1 consisted of DXS6807, DXS6800, DXS7424, DXS101, GATA172D05 and HPRTB and X-Multiplex 2 consisted of DXS8378, DXS9898, DXS6801, DXS6809, DXS6789, DXS7133, DXS8377 and DXS7423. In addition, we present a...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-011-0629-7
更新日期:2012-03-01 00:00:00
abstract::In the immigration case cited by Jeffreys et al. (1985), the biostatistical evaluation of blood group findings in 16 systems and of HLA-A,B findings for the mother and child, using a special kinship algorithm developed by Ihm and Hummel (1975), produced a probability of maternity of the Ghanaian-born putative mother o...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF01371238
更新日期:1992-01-01 00:00:00