Abstract:
:We describe new primers for the detection of the STR polymorphism at the CSF1PO locus. These primers have been designed to produce shorter amplicons (150-182 bp) than the primers in standard use (295-327 bp). The reliability of the new primers for CSF1PO typing has been demonstrated by testing on known samples and by sequence analysis. These primers are superior to the original primers with regard to electrophoretic resolution and utility for typing of severely degraded DNA.
journal_name
Int J Legal Medjournal_title
International journal of legal medicineauthors
Yoshida K,Sekiguchi K,Kasai K,Sato H,Seta S,Sensabaugh GFdoi
10.1007/BF02441025subject
Has Abstractpub_date
1997-01-01 00:00:00pages
36-8issue
1eissn
0937-9827issn
1437-1596journal_volume
110pub_type
杂志文章abstract:BACKGROUND:As sex estimation is an important step to delineate the biological profile, the development of tools employing anatomical structures which may maintain their integrity even after extreme events, such as the maxillary sinus, become useful for forensic identification. Thus, the aim in the present study was to ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-018-1869-6
更新日期:2019-07-01 00:00:00
abstract::Backspatter is the ejection of biological material from a gunshot entrance wound against the line of fire. This phenomenon was investigated experimentally in transverse gunshots to the heads of calves (n = 9) using two types of 9 mm Parabellum ammunition from shooting distances of 0-10 cm. The resulting bloodstains we...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF01355519
更新日期:1996-01-01 00:00:00
abstract::We present a duo paternity test case to assess the biological relationship between a woman and her female child. After analyzing 57 autosomal and 19 X-chromosomal short tandem repeat loci, mother-daughter exclusions were discovered at four loci, which were all located on chromosome 2. Further testing of whole-genome s...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-018-1857-x
更新日期:2019-07-01 00:00:00
abstract::A population database was generated from 118 unrelated Caucasoid individuals living in Spain. Sequence polymorphisms of the mitochondrial DNA (mtDNA) control region, hypervariable regions I and II (HVRI and HVRII) were determined using the polymerase chain reaction (PCR) and direct sequencing. A total of 102 different...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140000158
更新日期:2000-01-01 00:00:00
abstract::P-glycoprotein (P-gp), encoded by the ABCB1/MDR1 gene, is a drug transporter at the blood-brain barrier. Several polymorphisms in the ABCB1 gene are known to affect the activity and/or expression of P-gp, thereby influencing the treatment response and toxicity of P-gp substrates like citalopram and venlafaxine. In thi...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-013-0849-0
更新日期:2013-05-01 00:00:00
abstract::Allele frequencies and forensic statistics of 13 autosomal short tandem repeat loci were estimated in 56 unrelated Iranian individuals. Except for two loci which were monomorph, a total of 5-11 alleles at each locus were observed and altogether 94 alleles for all selected loci were found. Our results show that 11 out ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-016-1342-3
更新日期:2016-11-01 00:00:00
abstract::In many forensic cases, the existence of a traumatic brain injury (TBI) is an essential factor, and the determination of the survival time is nearly as important as the determination of whether or not a trauma exists. Since it is known that glucose uptake increases in injured brain cells in order to perpetuate the neu...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-018-1893-6
更新日期:2019-07-01 00:00:00
abstract::The estimation of the minimum postmortem interval can be implemented by age estimation of corpse-associated primary colonizers such as the blow flies (Diptera: Calliphoridae). In cases where pupae represent the oldest stages found on a body, their age must be added to the duration of prepupal development to estimate t...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-013-0922-8
更新日期:2014-05-01 00:00:00
abstract::When a forensic DNA sample cannot be associated directly with a previously genotyped reference sample by standard short tandem repeat profiling, the investigation required for identifying perpetrators, victims, or missing persons can be both costly and time consuming. Here, we describe the outcome of a collaborative s...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-012-0788-1
更新日期:2013-05-01 00:00:00
abstract::The assistance provided by specialised healthcare personnel to victims of a sexual violence cannot focus just on the clinical intervention appropriate for the lesions suffered by the patient, but must also take legal and forensic needs into account. Anamnestic data represents a crucial step towards the finding of fore...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-017-1602-x
更新日期:2017-09-01 00:00:00
abstract::Kinship relation and, in particular, paternity probability estimation using a Bayesian approach require the input of a priori probabilities of different hypotheses. In practical case work, a priori probabilities or priors, for short, must often be estimated using only common sense and symmetry arguments because in mos...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-013-0827-6
更新日期:2013-11-01 00:00:00
abstract::The present paper analyses the applicability of the clinically prevalent skeletal age determination method of Tanner and Whitehouse for forensic age estimation in living individuals. For this purpose, the hand X-rays from 48 boys and 44 girls aged 12-16 years were evaluated retrospectively. The minima and maxima, the ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-008-0237-3
更新日期:2008-07-01 00:00:00
abstract::In the immigration case cited by Jeffreys et al. (1985), the biostatistical evaluation of blood group findings in 16 systems and of HLA-A,B findings for the mother and child, using a special kinship algorithm developed by Ihm and Hummel (1975), produced a probability of maternity of the Ghanaian-born putative mother o...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF01371238
更新日期:1992-01-01 00:00:00
abstract::Determinations of chronologic age are of great importance in forensic science. At present the aspartic acid racemization method on teeth provides one of the best means in adult individuals. However, if teeth are not available, some other stable tissue has to be used. In this study, the applicability of cartilage from ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF01845611
更新日期:1995-01-01 00:00:00
abstract::Establishing individuality is an imperative aspect in any investigation procedure. At times, it becomes necessary to determine the sex of the individual to establish identity, and saliva stains found at the scene of crime are of major help in such cases. In the present study, we have determined the sex of the individu...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-008-0285-8
更新日期:2009-09-01 00:00:00
abstract::The molecular composition of the genetic substrate recovered from seven aged forensic samples has been extensively investigated. A simple enzymatic test based on DNAseI incubation of the extracts showed that the UV-fluorescent material from the forensic specimens is composed of nucleic acids, with the DNA fraction rep...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-002-0326-7
更新日期:2002-12-01 00:00:00
abstract::Medico-legal experts are increasingly enlisted to assess the methamphetamine and amphetamine serum concentrations after a criminal offense. However, since criminal users rarely provide useful information to medico-legal experts regarding the substances abused, when the substance(s) was/were used, dose of ingestion too...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-017-1607-5
更新日期:2017-09-01 00:00:00
abstract::Bone marrow (BM) analysis is of forensic interest for postmortem toxicological investigations where blood samples are unavailable or unusable. Due to the lack of studies, it remains difficult to interpret concentrations of xenobiotics measured in this matrix. Based on a statistical approach published previously to int...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-013-0833-8
更新日期:2013-09-01 00:00:00
abstract::Genetic diversity indices and forensic parameters at 20 autosomal short tandem repeat (STR) loci were evaluated in 541 unrelated individuals of north-western Indian state Rajasthan. In total, 243 alleles were observed with an average of 12.15 alleles per locus. The most polymorphic and discriminative locus was Penta E...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-020-02330-z
更新日期:2020-06-05 00:00:00
abstract::Abstract DNA typing of four tetrameric repeat loci (HUMVWA, HUMTH0I, D21SII and HPRT) was carried out in a Chinese Han population from Shanghai (East China) and one from Guangzhou (South-East China) using a quadruplex PCR amplification and detection of the fluorescent-labeled alleles on the ALF DNA sequencer. All loci...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140050187
更新日期:1998-01-01 00:00:00
abstract::In certain circumstances, tumour tissue specimens are the only DNA resource available for forensic DNA analysis. However, cancer tissues can show microsatellite instability and loss of heterozygosity which, if concerning the short tandem repeats (STRs) used in the forensic field, can cause misinterpretation of the res...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-010-0443-7
更新日期:2011-05-01 00:00:00
abstract::Uniparental disomy (UPD) has attracted more attention recently in paternity testing, though it is an infrequent genetic event. Although short tandem repeat (STR) profiling has been widely used in paternity testing, it is not sufficient to use STR only to judge the genetic relationship, because the existence of UPD wil...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-019-02215-w
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND:The aim of this study was to evaluate the sensitivity of postmortem computed tomography (PMCT), postmortem magnetic resonance imaging (PMMR) and PMCT angiography (PMCTA) compared with autopsy in cases of adult death investigations. METHODS:For this systematic review and meta-analysis, Embase, PubMed, Scopus...
journal_title:International journal of legal medicine
pub_type: 杂志文章,meta分析
doi:10.1007/s00414-019-02140-y
更新日期:2020-01-01 00:00:00
abstract::The systemic distribution of kerosene components in blood and tissues was analysed in rats following dermal exposure. Four types of trimethylbenzenes (TMBs) and aliphatic hydrocarbons (AHCs) with carbon numbers 9-16 (C(9)-C(16)) were analysed as major kerosene components by capillary gas chromatography/mass spectromet...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-001-0282-7
更新日期:2002-08-01 00:00:00
abstract::Brazilian population derives from Native Amerindians, Europeans, and Africans. Southeastern Brazil is the most populous region of the country. The present study intended to characterize the maternal genetic ancestry of 290 individuals from southeastern (Brazil) population. Thus, we made the sequencing of the three hyp...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-014-1023-z
更新日期:2014-07-01 00:00:00
abstract::Reports on penetrating ballistic head injuries in the literature are dominated by case studies of suicides; the penetrating ammunition usually being .22 rimfire or shotgun. The dominating cause of injuries in modern warfare is fragmentation and hence, this is the primary threat that military helmets protect the brain ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-014-1073-2
更新日期:2015-05-01 00:00:00
abstract::Chumbinho is the popular name given to carbamate aldicarb (Temik), an insecticide commonly used in agriculture and highly toxic (LD50 = 0.9 mg/kg oral in rats) that has been sold clandestinely in several regions of Brazil. Chumbinho is sold illegally as raticide and is available in a formulation of small black granule...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-016-1336-1
更新日期:2016-07-01 00:00:00
abstract::The purpose of the present research is to study the radiographic visibility of the periodontal ligament in third molars from a northern Chinese population to determine if this methodology could be used for the 18-year threshold. A total of 1300 conventional orthopantomograms from 650 males and 650 females of northern ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-017-1664-9
更新日期:2018-03-01 00:00:00
abstract::Drowning remains one of the major causes of death in most developed countries despite the fact that many of the victims are known to be at least moderate swimmers as well as healthy directly before the event. Here, fatal arrhythmias and especially the long QT syndrome (LQTS) have been proposed as the underlying mechan...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-015-1259-2
更新日期:2016-03-01 00:00:00
abstract::The main criteria used in dental age estimation in living young individuals are mineralisation and eruption of the third molars. In order to further diversify the spectrum of characteristics after completion of third molar development, tests were undertaken to determine whether the characteristics studied by Gustafson...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-012-0701-y
更新日期:2012-07-01 00:00:00