Abstract:
:We present a duo paternity test case to assess the biological relationship between a woman and her female child. After analyzing 57 autosomal and 19 X-chromosomal short tandem repeat loci, mother-daughter exclusions were discovered at four loci, which were all located on chromosome 2. Further testing of whole-genome single nucleotide polymorphisms confirmed that the daughter had complete uniparental disomy (UPD) of chromosome 2. This study presents a cautionary case demonstrating that hasty decisions of parentage exclusion should not be made when genetic markers on the same chromosome do not conform to Mendel's laws due to UPD.
journal_name
Int J Legal Medjournal_title
International journal of legal medicineauthors
Chen M,Jiang J,Li C,Ren H,Chen W,Liu Z,Cheng F,Zhao J,Chen T,Chen C,Yan Jdoi
10.1007/s00414-018-1857-xsubject
Has Abstractpub_date
2019-07-01 00:00:00pages
993-997issue
4eissn
0937-9827issn
1437-1596pii
10.1007/s00414-018-1857-xjournal_volume
133pub_type
杂志文章abstract::To better characterize the morphologic changes in electrocution, morphologic changes in the hearts of 21 subjects, who died instantaneously of electrocution, were compared to the hearts of decedents with different types of death. Sixteen myocardial samples per heart were processed for histological examination, and sec...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-005-0011-8
更新日期:2006-03-01 00:00:00
abstract::Due to the increasing significance of forensic age estimations in the age of globalisation, novel radiographic criteria besides clavicles and hand bones may provide additional certainty for forensic age expertises. The present study analyses the suitability of the iliac crest apophysis by means of 643 pelvic radiograp...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-012-0763-x
更新日期:2013-03-01 00:00:00
abstract::A system of nomenclature is proposed for the complex STR system ACTBP2 (SE33) in order to facilitate data exchange between laboratories. The nomenclature conforms to the ISFH recommendations as far as it is possible for such complex systems. A blind trial was carried out between up to 20 laboratories to ascertain the ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140050124
更新日期:1998-01-01 00:00:00
abstract::On September 23rd 1993 Genova was flooded by heavy rainstorms and 4 people disappeared, including an elderly couple. Four days later a partially skeletonized body was found floating near the coast. No visual identification was possible. Autopsy findings were consistent with the medical history of a possible victim. DN...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF01428409
更新日期:1995-01-01 00:00:00
abstract::The aim of this paper is twofold: first, to evaluate an Indian sample by Cameriere's European formula; and second, if this formula turns out to be unsuitable, to study a specific formula for Indian children. Orthopantomographs taken from 480 Indian children (227 girls and 253 boys) aged between 3 and 15 years were ana...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-010-0427-7
更新日期:2010-05-01 00:00:00
abstract::Forensic age estimation of living individuals has become increasingly important in forensic practice with the constant increase of migration movements to developed countries. The method of Greulich and Pyle is one of the most frequently used methods for age determination. The aim of our study was to verify the reliabi...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-014-1028-7
更新日期:2015-01-01 00:00:00
abstract::When a forensic DNA sample cannot be associated directly with a previously genotyped reference sample by standard short tandem repeat profiling, the investigation required for identifying perpetrators, victims, or missing persons can be both costly and time consuming. Here, we describe the outcome of a collaborative s...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-012-0788-1
更新日期:2013-05-01 00:00:00
abstract::Necrophagous blow fly larvae can provide accurate estimates of the minimum postmortem interval in death investigations. During larval development, predictable morphological changes occur and measurements of weight, length, and width are compared to species-specific growth curves for reliable age estimates. However, ag...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-012-0699-1
更新日期:2013-01-01 00:00:00
abstract::Bullet velocity is a basic parameter in wound ballistics studies. It is usually measured electronically by means of a variety of solid or photoelectric barriers connected to equipment measuring the time elapsing between impulses, enabling the velocity to be calculated. With the advent of Doppler radar velocity measure...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF01247266
更新日期:1994-01-01 00:00:00
abstract::Allele frequencies of the Short tandem repeat systems HumVWA and HumACTBP2 were determined from 105 unrelated individuals from the area of Szeged, Hungary. A total of 8 alleles was detected for VWA, and 23 alleles were found for ACTBP2. In both systems no deviations from Hardy-Weinberg equilibrium were observed. A com...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF02432127
更新日期:1996-01-01 00:00:00
abstract::CT scan coupled with autopsy is the gold standard for the forensic investigation of fatal road traffic accidents. The objective of the present paper is to demonstrate that from this, it is possible to reconstruct elements of an accident with minimal human and material resources using basic knowledge of three-dimension...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-012-0789-0
更新日期:2013-09-01 00:00:00
abstract::Bloodstained threads (1 cm in length) were tested to identify human origin by a direct ELISA-ABC method using biotinylated antibody against human HbA0. By this method human bloodstains were clearly distinguishable from bloodstains of other species including Japanese monkey. The minimum detection limit of bloodstains p...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF01369714
更新日期:1991-01-01 00:00:00
abstract::Blunt thoracic aortic injury (BTAI) resulting from cardiopulmonary resuscitation (CPR) is rarely reported and most reports are of aortic rupture. Clinical reports have also documented aortic dissection and intramural hematomas with sequential imaging showing the development of these aortic injuries after the administr...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-016-1377-5
更新日期:2016-11-01 00:00:00
abstract::Plant exposures are among the most frequently reported cases to poison control centres worldwide. This is a growing condition due to recent societal trends oriented towards the consumption of wild plants as food, cosmetics, or medicine. At least three general causes of plant poisoning can be identified: plant misident...
journal_title:International journal of legal medicine
pub_type: 杂志文章,评审
doi:10.1007/s00414-016-1460-y
更新日期:2017-01-01 00:00:00
abstract::BamHI polymorphism at the VNTR locus D2S44 was investigated, concentrating on band frequencies, mutation rate and confirmation of Mendelian inheritance. In this series 39 restriction fragments showing frequencies less than 10% could clearly be distinguished. No mutations could be observed and the Mendelian character o...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF01816481
更新日期:1990-12-01 00:00:00
abstract::A study of the genetic variability in the Chueta (Majorcan Jews) and the Balearic (Majorca and Minorca Islands) populations was carried out using a multiplex system containing the nine tetrameric STRs D3S1358, vWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317 and D7S820. The Chueta population has remained isolated be...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004149900101
更新日期:2000-01-01 00:00:00
abstract::In forensic pathology routine, fatal cases of contrast agent exposure can be occasionally encountered. In such situations, beyond the difficulties inherent in establishing the cause of death due to nonspecific or absent autopsy and histology findings as well as limited laboratory investigations, pathologists may face ...
journal_title:International journal of legal medicine
pub_type: 杂志文章,评审
doi:10.1007/s00414-013-0912-x
更新日期:2014-01-01 00:00:00
abstract::In cooperation with the Crime Investigation Agency (Landeskriminalamt) of North Rhine-Westphalia, we carried out a study of 150 cases of (suspected) neonaticide dating from 1993 to 2007 from all over Germany. The autopsy reports and additional expert opinions (if performed) were evaluated for a minimum of 78 variables...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-013-0841-8
更新日期:2013-05-01 00:00:00
abstract::We demonstrate the applicability of ion-pair reversed-phase high-performance liquid chromatography-electrospray ionization time-of-flight mass spectrometry (ICEMS) for the simultaneous characterization of length and nucleotide polymorphisms. Two sections within the first (HVS-I) and second (HVS-II) hypervariable segme...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-006-0117-7
更新日期:2007-01-01 00:00:00
abstract::The current knowledge base for evaluating the influence of ethnic origin on wisdom tooth eruption is still inadequate. We therefore analyzed and compared the chronology of wisdom tooth eruption in three ethnic populations-German, Japanese, and black South African-based on evidence from 2,482 conventional orthopantomog...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-007-0171-9
更新日期:2007-11-01 00:00:00
abstract::Allele frequencies at the short tandem repeat (STR) loci HumACTBP2 and HumVWA were determined in 118 unrelated individuals from Northern Italy (Milan area). For locus HumACTBP2 (SE33) a total of 39 alleles was observed. Furthermore, two interalleles (N18m+N19m) and one allele (> N35) were found which were not observed...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140050090
更新日期:1997-01-01 00:00:00
abstract::Stabbing with a kitchen knife is a common method of homicide in Europe. Serrated knives may leave tool markings (striations) in tissues. Documentation of striations is necessary for their use as forensic evidence. Traditional methods (physical casting and photography) have significant limitations, and micro-computed t...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-017-1715-2
更新日期:2018-03-01 00:00:00
abstract::Mitochondrial DNA (mtDNA) from 100 unrelated British White Caucasians was extracted, amplified and directly sequenced. Sequences of approximately 800 nucleotides were obtained from 2 hypervariable segments within the non-coding region of the mitochondrial genome. A total of 91 different sequences were observed with an...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF01225046
更新日期:1993-01-01 00:00:00
abstract::Single nucleotide polymorphism (SNP) typing offers promise to forensic genetics. Various strategies and panels for analyzing SNP markers for individual identification have been published. However, the best panels with fewer identity SNPs for all major population groups are still under discussion. This study aimed to f...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-015-1250-y
更新日期:2016-01-01 00:00:00
abstract::One of the fundamental questions in forensic medicine and anthropology is whether or not a bone or bone fragment is human. Surprisingly at times for the extreme degradation of the bone (charred, old), DNA cannot be successfully performed and one must turn to other methods. Histological analysis at times can be propose...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-018-1781-0
更新日期:2018-09-01 00:00:00
abstract::Haemorrhages at the periostal-clavicular origin of the sternocleidomastoid muscles were found in 52 out of 54 cases of death by hanging. This cervical haemorrhage is most frequently found in death by hanging, but only seldomly seen in other causes of death and can therefore be regarded as being typical for death by ha...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF01844825
更新日期:1995-01-01 00:00:00
abstract::The diagnosis of drowning is one of the most difficult in forensic medicine. Forensic diatomology has been proposed to be useful in solving the diagnosis of drowning and considered to be a reliable indicator of the site of drowning. The Yangtze River and Jialing River are the main rivers in the Chongqing area (China),...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-020-02297-x
更新日期:2020-07-01 00:00:00
abstract:BACKGROUNDS:Aortic rupture or dissection as immediate cause of sudden death is encountered in forensic and clinical autopsy practice. Despite a common denominator of 'sudden aortic death' (SAD), we expect that in both settings the diagnostic workup, being either primarily legal or primarily disease related, differs sub...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-017-1560-3
更新日期:2017-11-01 00:00:00
abstract:PURPOSE:The aim of this multi-reader feasibility study was to evaluate new post-processing CT imaging tools in rib fracture assessment of forensic cases by analyzing detection time and diagnostic accuracy. MATERIALS AND METHODS:Thirty autopsy cases (20 with and 10 without rib fractures in autopsy) were randomly select...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-016-1412-6
更新日期:2017-03-01 00:00:00
abstract::We have sequenced the entire mtDNA genome (mtGenome) of 241 individuals who match 1 of 18 common European Caucasian HV1/HV2 types, to identify sites that permit additional forensic discrimination. We found that over the entire mtGenome even individuals with the same HV1/HV2 type rarely match. Restricting attention to ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-004-0427-6
更新日期:2004-06-01 00:00:00