Allergic reactions following contrast material administration: nomenclature, classification, and mechanisms.

Abstract:

:In forensic pathology routine, fatal cases of contrast agent exposure can be occasionally encountered. In such situations, beyond the difficulties inherent in establishing the cause of death due to nonspecific or absent autopsy and histology findings as well as limited laboratory investigations, pathologists may face other problems in formulating exhaustive, complete reports, and conclusions that are scientifically accurate. Indeed, terminology concerning adverse drug reactions and allergy nomenclature is confusing. Some terms, still utilized in forensic and radiological reports, are outdated and should be avoided. Additionally, not all forensic pathologists master contrast material classification and pathogenesis of contrast agent reactions. We present a review of the literature covering allergic reactions to contrast material exposure in order to update used terminology, explain the pathophysiology, and list currently available laboratory investigations for diagnosis in the forensic setting.

journal_name

Int J Legal Med

authors

Palmiere C,Comment L,Mangin P

doi

10.1007/s00414-013-0912-x

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

95-103

issue

1

eissn

0937-9827

issn

1437-1596

journal_volume

128

pub_type

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