Abstract：
:We developed two multiplex systems for the coamplification of X-chromosomal short tandem repeats (STRs). X-Multiplex 1 consisted of DXS6807, DXS6800, DXS7424, DXS101, GATA172D05 and HPRTB and X-Multiplex 2 consisted of DXS8378, DXS9898, DXS6801, DXS6809, DXS6789, DXS7133, DXS8377 and DXS7423. In addition, we present allele frequencies for these loci in a south Brazilian population comprising 124 females and 141 males and haplotype frequencies of linked markers for males. Hardy-Weinberg equilibrium (HWE) was tested in the female sample and no significant deviations were found after applying Bonferroni's correction. Linkage disequilibrium (LD) tests were performed for all pairs of loci and three significant results, out of 91 pairwise comparisons, were obtained. We did not find any evidence of linkage disequilibrium between close or linked markers. The power of discrimination in females (PD(F)) varied between 0.832 for DXS6801 and 0.987 for DXS8377. DXS6801 was the least informative marker (PIC = 0.605), while DXS8377 was the most polymorphic (PIC = 0.911), followed by DXS101 (PIC = 0.872). Genetic distances were estimated for each STR marker applying the calculation of F (ST) between our total sample and other studies from Brazil, Europe, Asia and Africa. The most distant populations were Japan, Korea, China, Ghana and Uganda.
journal_name
Int J Legal Medjournal_title
International journal of legal medicineauthors
Penna LS,Silva FG,Salim PH,Ewald G,Jobim M,Magalhães JA,Jobim LFdoi
10.1007/s00414-011-0629-7subject
Has Abstractpub_date
2012-03-01 00:00:00pages
327-30issue
2eissn
0937-9827issn
1437-1596journal_volume
126pub_type
杂志文章abstract：:A 28-year-old man was shot in the back of the head at close range by a robber who then locked him in a room assuming that he was dead. The man was discovered 2 days later. The entrance wound of the bullet was in the left occipital region and it passed into the periphery of the right temporal lobe, where it lodged. The...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004149900120
更新日期：2000-01-01 00:00:00
abstract：:The case concerns the sudden death of a 21-year-old male during a soccer game. The autopsy revealed large, calcified saccular aneurysms at the origins of both the left anterior descending and the right coronary arteries. Histologically, the wall of the aneurysms was thin and composed of an internal fibro-calcified lay...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140050213
更新日期：1999-01-01 00:00:00
abstract：:The purpose of this study is to evaluate allelic association and linkage of 18 adjacent syntenic short tandem repeat (STR) pairs form out of 30 markers located on 12 different autosomes. Linkage disequilibrium was tested by using the unknown gametic phase genotypes and phased haplotypes from 290 unrelated individuals ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-014-1032-y
更新日期：2014-09-01 00:00:00
abstract：:Scars of human skin can on occasions provide a very useful ancillary method of identification of an unknown deceased. If the age of any visible scars can be estimated objectively, then this might be of some assistance in the identification procedure. Melanocytes migrate into scar tissue as it ages and their number wit...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140100225
更新日期：2001-10-01 00:00:00
abstract：:The aim of this paper is twofold: first, to evaluate an Indian sample by Cameriere's European formula; and second, if this formula turns out to be unsuitable, to study a specific formula for Indian children. Orthopantomographs taken from 480 Indian children (227 girls and 253 boys) aged between 3 and 15 years were ana...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-010-0427-7
更新日期：2010-05-01 00:00:00
abstract：:A single-tube multiplex assay of a small set of ancestry-informative markers (AIMs) for effectively estimating individual ancestry and admixture is an ideal forensic tool to trace the population origin of an unknown DNA sample. We present a newly developed 27-plex single nucleotide polymorphism (SNP) panel with highly...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-015-1183-5
更新日期：2016-01-01 00:00:00
abstract：:An obese man (height, 178 cm; weight, 160 kg; body mass index, 50.5 kg/m2) with a history of recurrent ventricular tachycardia (VT), cardiomyopathy, coronary sclerosis, and insulin-resistant diabetes suffered a right femur fracture in a vehicular accident. His fracture was repaired the following day, but shortly after...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-016-1392-6
更新日期：2016-11-01 00:00:00
abstract：:Allele frequencies and forensic parameters for 17 autosomal short tandem repeat (STR) loci were investigated from 1542 individuals of Va ethnic minority in Yunnan Province in the southwest of China. Also, genetic distances between Va and 13 published populations were compared, and a neighbor-joining (NJ) phylogenetic ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-017-1620-8
更新日期：2017-09-01 00:00:00
abstract：:Single nucleotide polymorphism (SNP) typing offers promise to forensic genetics. Various strategies and panels for analyzing SNP markers for individual identification have been published. However, the best panels with fewer identity SNPs for all major population groups are still under discussion. This study aimed to f...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-015-1250-y
更新日期：2016-01-01 00:00:00
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journal_title：International journal of legal medicine
pub_type： 杂志文章,多中心研究
doi：10.1007/s00414-006-0100-3
更新日期：2006-11-01 00:00:00
abstract：:Cyanide (CN) blood concentration is hardly considered during routine when evaluating smoke gas intoxications and fire victims, although some inflammable materials release a considerable amount of hydrogen cyanide. CN can be significant for the capacity to act and can in the end even be the cause of death. Systematic d...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-016-1426-0
更新日期：2017-01-01 00:00:00
abstract：:The use of phenethylamines in the dance scene is now well established. Apart from amphetamine, the commonest phenethylamine encountered in clinical and forensic settings is 3,4-methylenedioxymethamphetamine (MDMA) commonly known as ecstasy. Other phenethylamines, which have similar effects are encountered, such as 3,4...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140050291
更新日期：2000-01-01 00:00:00
abstract：:One of the most common conditions during fetal development is anencephaly, which often involves many identification difficulties in the context of physical anthropology, as it causes severe skull challenges. In this paper, we describe the alterations found in the skulls of two perinatal individuals with anencephaly fr...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-014-1123-9
更新日期：2015-07-01 00:00:00
abstract：:Population studies on six short tandem repeat loci, HUMF13A01, HUMFXIIIB, HUMLIPOL, HUMTH01, HUMTPOX and HUMVWFA31 were carried out in a sample of unrelated Japanese individuals (n = 337-545) living in Gifu Prefecture (central region of Japan). Five alleles could be identified for HUMFXIIIB, six for HUMF13A01, HUMLIPO...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/BF01369599
更新日期：1996-01-01 00:00:00
abstract：:We present the case of a 3.5-year-old boy with sudden anal blood loss at school. Sexual abuse was suspected, and, apart from anal fissures seen on sigmoidoscopy, no other clinical signs of any sort of disorder were present. As no medical explanation for the blood loss could be given, penetrating anal trauma was sugges...
journal_title：International journal of legal medicine
pub_type： 杂志文章,评审
doi：10.1007/s00414-005-0053-y
更新日期：2007-01-01 00:00:00
abstract：:A short tandem repeat at the D1S1656 locus was sequenced in 45 selected alleles and 13 different alleles were found which were designated according to the total number of repeats. This STR is a compound hypervariable STR consisting of blocks of (TAGR) repeats with a basic sequence structure (TAGA)4(TGA)0-1(TAGA)6-16(T...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140050161
更新日期：1998-01-01 00:00:00
abstract：:Estimation of age in individuals has received considerable attention in the forensic literature. The reduction of size of dental pulp cavity as a result of secondary dentin deposit with increasing age could be used as an indicator of age. This regression change, apart from morphological techniques, can also be analyse...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-008-0268-9
更新日期：2009-03-01 00:00:00
abstract：:Determining the time of injury is an important but still a challenging task in forensic anthropology. In literature, many descriptions can be found to make a distinction between perimortem and postmortem fractures. Characteristics that are more related to fractures in fresh conditions, however, are not extensively inv...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-016-1514-1
更新日期：2017-05-01 00:00:00
abstract：:Bullet velocity is a basic parameter in wound ballistics studies. It is usually measured electronically by means of a variety of solid or photoelectric barriers connected to equipment measuring the time elapsing between impulses, enabling the velocity to be calculated. With the advent of Doppler radar velocity measure...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/BF01247266
更新日期：1994-01-01 00:00:00
abstract：:Myocardial pathology and cardiac functional abnormalities known to occur in association with chronic alcohol abuse have been attributed to a direct toxic effect of ethanol on the intra-myocardial vasculature: alcohol-induced occlusion of small arteries with consequent secondary ischaemia leads to individual myocyte lo...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/BF01225513
更新日期：1996-01-01 00:00:00
abstract：:It is difficult to carry out toxicological investigations in biological samples collected from extensively decomposed bodies and to interpret obtained results as several pitfalls should be considered: redistribution phenomena, degradation of xenobiotics during the postmortem period, contamination by putrefaction fluid...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-020-02267-3
更新日期：2020-07-01 00:00:00
abstract：INTRODUCTION:The determination of age of majority (the 18-year-old threshold) using the popular Demirjian tooth staging method is unreliable, so other maturity markers are required. This study examines whether the Root Pulp Visibility (RPV) of the mandibular third molar is a useful indicator of age. METHODS:One thousa...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-019-02155-5
更新日期：2020-01-01 00:00:00
abstract：:Postmortem MRI (PMMR) examinations are seldom performed in legal medicine due to long examination times, unfamiliarity with the technique, and high costs. Furthermore, it is difficult to obtain access to an MRI device used for patients in clinical settings to image an entire human body. An alternative is available: ex...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-014-1058-1
更新日期：2015-05-01 00:00:00
abstract：:In a knife attack the perpetrator can unintentionally injure his own hand, if the knife does not have an adequate handguard and the tip of the blade hits a solid, mostly bony structure while being violently thrust into the victim's body. The injuries occurring under these conditions are localized on the flexor side of...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-004-0491-y
更新日期：2004-12-01 00:00:00
abstract：:The authors report on a young boy who was bitten into his face by an unknown animal while being asleep in a tent. Given the bite marks and the location of the scene, members of the mustelidae and canidae families were the first "suspects." Deoxyribunucleic acid (DNA) recovered from the tent's wall was analyzed with re...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-012-0674-x
更新日期：2012-05-01 00:00:00
abstract：:A method has been developed for the simultaneous determination of lysergic acid diethylamide (LSD), its epimer iso-LSD, and its main metabolites nor-LSD and 2-oxo-3-hydroxy LSD in blood, urine, and, for the first time, vitreous humor samples. The method is based on liquid/liquid extraction and liquid chromatography-mu...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-006-0078-x
更新日期：2007-07-01 00:00:00
abstract：:DNA typing was carried out on epithelial cells which were transferred from the hands of the suspect onto the neck of the victim. In an experimental study 16 suspect-victim combinations were investigated for estimating the typing success. Alternatively to an attack against the neck, the upper arm was used for "strangul...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140050063
更新日期：1997-01-01 00:00:00
abstract：:Determination of electrolyte concentrations (mainly potassium) in vitreous humour has long been considered an important tool in human death investigations for the estimation of the post-mortem interval (PMI). On the basis of its well known potential in ion analysis, capillary zone electrophoresis (CZE) has recently be...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140100239
更新日期：2002-02-01 00:00:00
abstract：:The present study aimed to evaluate the accuracy of mandibular measurements for sex determination in a Brazilian population. The sample was composed of 100 mandibles, of which 53 were female and 47 were male, and the average age was 57.03 years. The mandible measurement protocol was composed of 15 measurements, of whi...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-017-1681-8
更新日期：2018-05-01 00:00:00
abstract：:In cooperation with the Crime Investigation Agency (Landeskriminalamt) of North Rhine-Westphalia, we carried out a study of 150 cases of (suspected) neonaticide dating from 1993 to 2007 from all over Germany. The autopsy reports and additional expert opinions (if performed) were evaluated for a minimum of 78 variables...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-013-0841-8
更新日期：2013-05-01 00:00:00
