Abstract:
:From sequence database information, we have identified two male-specific and polymorphic tetranucleotide STRs, DYS 441 (GDB:10013873) and DYS 442 (GDB: 10030304), on the Y chromosome. Analysis of 184 males allowed 7 and 5 alleles to be distinguished in the DYS 441 and DYS 442 systems, respectively, yielding 21 haplotypes. The gene diversities were 0.72 and 0.51, respectively and the haplotype diversity was 0.85.
journal_name
Int J Legal Medjournal_title
International journal of legal medicineauthors
Iida R,Tsubota E,Matsuki Tdoi
10.1007/s004140100207subject
Has Abstractpub_date
2001-08-01 00:00:00pages
54-6issue
1eissn
0937-9827issn
1437-1596journal_volume
115pub_type
杂志文章abstract::Population studies on six short tandem repeat loci, HUMF13A01, HUMFXIIIB, HUMLIPOL, HUMTH01, HUMTPOX and HUMVWFA31 were carried out in a sample of unrelated Japanese individuals (n = 337-545) living in Gifu Prefecture (central region of Japan). Five alleles could be identified for HUMFXIIIB, six for HUMF13A01, HUMLIPO...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF01369599
更新日期:1996-01-01 00:00:00
abstract::Abstract DNA typing of four tetrameric repeat loci (HUMVWA, HUMTH0I, D21SII and HPRT) was carried out in a Chinese Han population from Shanghai (East China) and one from Guangzhou (South-East China) using a quadruplex PCR amplification and detection of the fluorescent-labeled alleles on the ALF DNA sequencer. All loci...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140050187
更新日期:1998-01-01 00:00:00
abstract::Drowning remains one of the major causes of death in most developed countries despite the fact that many of the victims are known to be at least moderate swimmers as well as healthy directly before the event. Here, fatal arrhythmias and especially the long QT syndrome (LQTS) have been proposed as the underlying mechan...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-015-1259-2
更新日期:2016-03-01 00:00:00
abstract::To determine the cause of death in myocardial ion channel diseases (MICD)-induced sudden cardiac death (SCD) cases is a difficulty in forensic identification practices. The majority of MICD-induced SCD cases would experience lethal ventricular tachyarrhythmia (LVTA) before deaths; thus, confirming the occurrence of LV...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-017-1710-7
更新日期:2018-03-01 00:00:00
abstract::A population study in a sample of 211 unrelated individuals from 2 cities in North and Central Italy was carried out to investigate the short tandem repeat (STR) system HUMVWA31. Separation of PCR- amplified DNA fragments was performed by high-resolution horizontal denaturing polyacrylamide gel electrophoresis (PAGE) ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF01428399
更新日期:1995-01-01 00:00:00
abstract::A 49-year-old white male was found lying unconscious at home. He had vomited, his mouth was filled with a white foam and a pungent odour filled the room. After emergency treatment blood, urine and stomach contents were screened for drugs after acid and alkaline extraction with subsequent derivatisation and GC-MS analy...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140050080
更新日期:1997-01-01 00:00:00
abstract::Carisoprodol is commonly prescribed as a centrally acting muscle relaxant, but it is also subject to abuse. The literature describing fatal intoxications with the drug is limited to a relatively small number of cases, and there are inconsistencies with regard to which concentration levels that are toxic. We therefore ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-006-0139-1
更新日期:2007-09-01 00:00:00
abstract::In many countries, assessment of legal age, also known as age of majority, has become increasingly important over the years. In China, individuals older than 18 years of age have full capacity regarding civil conduct and can be tried as an adult for criminal charges. Therefore, from a legal point of view, it is crucia...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-018-1907-4
更新日期:2018-11-01 00:00:00
abstract::When preparing forensic age estimates for living subjects over 18 years of age, it is crucial to evaluate the stage of ossification of the medial clavicular epiphysis. The establishment of radiation-free imaging techniques for assessment of clavicular ossification would be desirable in order to reduce the radiation ex...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-007-0220-4
更新日期:2008-03-01 00:00:00
abstract::A publically available database of the most highly cited scientists in all disciplines was used to identify people that belonged to the subject category "forensic science and legal medicine." This bibliometric information was derived from Elsevier's SCOPUS database containing eight million scientists with at least fiv...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-020-02491-x
更新日期:2021-01-02 00:00:00
abstract::A study of the genetic variability in the Chueta (Majorcan Jews) and the Balearic (Majorca and Minorca Islands) populations was carried out using a multiplex system containing the nine tetrameric STRs D3S1358, vWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317 and D7S820. The Chueta population has remained isolated be...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004149900101
更新日期:2000-01-01 00:00:00
abstract::ABO blood grouping of human bloodstains was performed by a sandwich ELISA using a species-specific monoclonal antibody to the amino-terminal cytoplasmic domain of human red cell membrane band 3. In a blind trial, all A, B and O bloodstains (a 1 cm long thread) and AB bloodstains (a 1.5 cm long thread) were accurately ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF01642795
更新日期:1993-01-01 00:00:00
abstract::Performance of PowerPlex Fusion 6C kit (PP F6C) was assessed in 374 unrelated individuals belonging to Madhya Pradesh, an Indian state. The study evaluated the forensic parameters for the loci included in PP F6C Multiplex System. The combined discrimination power (CPD) and combined exclusion power (CPE) were 1 and 0.9...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-019-02017-0
更新日期:2019-05-01 00:00:00
abstract::We report a simultaneous study of the VWA STR locus by the Perkin-Elmer Profiler Plus kit and the Promega GenePrint CTTv kit in a population sample from North Portugal and in 418 meiosis from family material and paternity cases. PCR amplification and genotyping were performed according to the manufacturer's instructio...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140100215
更新日期:2001-10-01 00:00:00
abstract::The population origin of an individual is often requested to be determined from specimens left at a crime scene for identifying a suspect and individual identity. The melanocortin 1 receptor gene (MC1R) and P gene are associated with human pigmentation. Although several studies have reported that these genes are highl...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-008-0289-4
更新日期:2009-05-01 00:00:00
abstract::Bone marrow (BM) analysis is of forensic interest for postmortem toxicological investigations where blood samples are unavailable or unusable. Due to the lack of studies, it remains difficult to interpret concentrations of xenobiotics measured in this matrix. Based on a statistical approach published previously to int...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-013-0833-8
更新日期:2013-09-01 00:00:00
abstract::We describe new primers for the detection of the STR polymorphism at the CSF1PO locus. These primers have been designed to produce shorter amplicons (150-182 bp) than the primers in standard use (295-327 bp). The reliability of the new primers for CSF1PO typing has been demonstrated by testing on known samples and by ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF02441025
更新日期:1997-01-01 00:00:00
abstract::An 89-year-old woman was found dead lying in her bed. Autopsy demonstrated a pronounced thickening of all coronary arteries except for the first 2-4 cm. Death was due to a recent myocardial infarction. Microscopically, the coronary arteries showed a substantial concentric thickening of all three layers with 90% narrow...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-006-0090-1
更新日期:2006-11-01 00:00:00
abstract::When blood reaches an extracorporeal surface, a drying process is initiated. Properties of this drying process may be crucial for the correct assessment of case-specific time lapses, however, there is a lack of systematic studies concerning the drying times of blood. We present a study on drying properties of small bl...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-012-0734-2
更新日期:2012-09-01 00:00:00
abstract::This paper describes the general design and main results of the Italian proficiency testing program for the analysis of psychoactive substances in urine, a long-term initiative created in 1995 on an educational basis and characterized by an innovative internet-based service for data exchange between laboratories and t...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140050279
更新日期:1999-01-01 00:00:00
abstract::The tetrameric STRs, HUMTH01, HUMVWA31A and HUMFES/FPS, were studied in a population from the Basque Country (northern Spain) for their frequency distribution and applicability to identity and paternity testing. All systems conformed to Hardy-Weinberg equilibrium; pairwise comparisons demonstrated the allelic independ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF01245481
更新日期:1995-01-01 00:00:00
abstract::Cyanide (CN) blood concentration is hardly considered during routine when evaluating smoke gas intoxications and fire victims, although some inflammable materials release a considerable amount of hydrogen cyanide. CN can be significant for the capacity to act and can in the end even be the cause of death. Systematic d...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-016-1426-0
更新日期:2017-01-01 00:00:00
abstract::Bee and wasp stings represent an uncommon cause of death. In a retrospective study of all fatalities due to venomous animals in Sweden during a 10-year-period, we found 19 fatalities due to wasps, 1 due to bees but none due to snake bite. This gives an annual incidence of 0.2 per million inhabitants. Most of the decea...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF01626039
更新日期:1991-03-01 00:00:00
abstract::DNA-based prediction for externally visible characteristics such as eye color is already a useful tool in forensic criminal investigations. The IrisPlex system, consisting of six single nucleotide polymorphisms (SNPs) and a prediction model, was developed based on individuals from several European populations. Other r...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-013-0953-1
更新日期:2014-05-01 00:00:00
abstract::In wounds that are inflicted at least 60 min before death, histamine levels can increase up to 100%. This functional effect might have a morphometric counterpart. Mast cells play a crucial role in acute inflammatory reactions and in the healing process of wounds. Therefore, the density of these cells was immunohistoch...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-002-0304-0
更新日期:2003-02-01 00:00:00
abstract::Gene expression analyses based on messenger RNA (mRNA) profiling require accurate data normalisation. When using endogenous reference genes, these have to be validated carefully. Therefore, we examined the transcript stability of 10 potential reference genes using quantitative real-time polymerase chain reaction: beta...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-010-0433-9
更新日期:2010-09-01 00:00:00
abstract::CT scan coupled with autopsy is the gold standard for the forensic investigation of fatal road traffic accidents. The objective of the present paper is to demonstrate that from this, it is possible to reconstruct elements of an accident with minimal human and material resources using basic knowledge of three-dimension...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-012-0789-0
更新日期:2013-09-01 00:00:00
abstract::Advances in forensic identification using molecular genetics are helpful in resolving some historical mysteries. The aim of this study was to confirm the authenticity of shrunken-head artifacts exhibited by two Polish museums. Shrunken heads, known as tsantsas, were headhunting trophies of South American Indians (Jiva...
journal_title:International journal of legal medicine
pub_type: 历史文章,杂志文章
doi:10.1007/s00414-016-1448-7
更新日期:2017-05-01 00:00:00
abstract::This paper investigates the effects that different summary statistics (minimum, median, mean, or maximum), temporal sampling resolutions (duration between sampling events), and sample sizes (number of individuals sampled per sampling event) had on the accuracy and precision of the regression coefficients of a typical ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-008-0243-5
更新日期:2008-09-01 00:00:00
abstract::The accuracy of most age determination methods in adults is unsatisfactory and therefore more precise methods are required. Teeth provide several useful points about an individuals age. With advancing age secondary dentine is deposited along the wall of the dental pulp chamber leading to a reduction in the size of the...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-004-0492-x
更新日期:2005-01-01 00:00:00