Abstract:
:The utility of postmortem microbiology has continuously been a topic of controversy. The present study describes a case of fatal sepsis in a patient with systemic lupus erythematosus. Postmortem culture and genotyping analyses allowed us to identify Klebsiella pneumoniae as the cause of sepsis, revealing the inadequateness of antimicrobial therapy.
journal_name
Int J Legal Medjournal_title
International journal of legal medicineauthors
D'Ovidio C,Pompilio A,Crocetta V,Gherardi G,Carnevale A,Di Bonaventura Gdoi
10.1007/s00414-015-1160-zsubject
Has Abstractpub_date
2015-09-01 00:00:00pages
1097-101issue
5eissn
0937-9827issn
1437-1596journal_volume
129pub_type
杂志文章abstract::One of the fundamental questions in forensic medicine and anthropology is whether or not a bone or bone fragment is human. Surprisingly at times for the extreme degradation of the bone (charred, old), DNA cannot be successfully performed and one must turn to other methods. Histological analysis at times can be propose...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-018-1781-0
更新日期:2018-09-01 00:00:00
abstract::To investigate the genetic variation and forensic efficiency of 19 X-STR loci in the Zhuang and Mulao minorities, we calculated allele frequencies, forensic parameters, and haplotype frequencies of 405 Zhuang and 234 Mulao unrelated healthy individuals from Guangxi Zhuang Autonomous Region of China. Furthermore, we an...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-019-02004-5
更新日期:2020-03-01 00:00:00
abstract::The purpose of this study is to evaluate allelic association and linkage of 18 adjacent syntenic short tandem repeat (STR) pairs form out of 30 markers located on 12 different autosomes. Linkage disequilibrium was tested by using the unknown gametic phase genotypes and phased haplotypes from 290 unrelated individuals ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-014-1032-y
更新日期:2014-09-01 00:00:00
abstract::Blood, saliva, and semen are some of the forensically most relevant biological stains commonly found at crime scenes, which can often be of small size or challenging due to advanced decay. In this context, it is of great importance to possess reliable knowledge about the effects of degradation under different environm...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-016-1373-9
更新日期:2016-11-01 00:00:00
abstract::Short tandem repeats (STRs) are DNA regions with a variable number of repeated units (2-6 bp) and attractive to genetic application like forensic, population genetics, and anthropological studies. The Huaxia Platinum System allows the multiplex amplification of 23 autosomal STR loci and two gender determination loci. ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-017-1679-2
更新日期:2018-07-01 00:00:00
abstract::The systemic distribution of kerosene components in blood and tissues was analysed in rats following dermal exposure. Four types of trimethylbenzenes (TMBs) and aliphatic hydrocarbons (AHCs) with carbon numbers 9-16 (C(9)-C(16)) were analysed as major kerosene components by capillary gas chromatography/mass spectromet...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-001-0282-7
更新日期:2002-08-01 00:00:00
abstract::In Japan and elsewhere, ABO genotyping is frequently used in forensic practice for identification of a decomposed body. However, the phenotype deduced from the genotyping data is occasionally inconsistent with the real phenotype. In this paper, we report a simple ABO genotyping method in which five single nucleotide p...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-006-0148-0
更新日期:2008-01-01 00:00:00
abstract::The original version of this article unfortunately contained a mistake in the Results section. The correct equation from the cubic regression analysis for male is: Age = 14.408 + 0.475X-0.064X2 + 0.005X3, and for the female is: 18.196-1.637X + 0.204X2-0.005X3. The error doesn't affect the main conclusion. ...
journal_title:International journal of legal medicine
pub_type: 杂志文章,已发布勘误
doi:10.1007/s00414-017-1751-y
更新日期:2018-01-01 00:00:00
abstract::Acute aortic dissection (AAD) is a clinically "silent," but emergent and life-threatening cardiovascular disease, and hereditary factors play an important etiologic role in the development of AAD. The purposes of this study are to definitize the diagnostic yield of 59 AAD patients, investigate the molecular pathologic...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-018-1890-9
更新日期:2018-09-01 00:00:00
abstract::Insertion-deletion (INDEL) markers are very frequent in the human genome and present several advantages for population and forensic studies, such as low mutation rates, easy interpretation, small amplicons, easy genotyping, and the possibility of using multiplex PCR. The great adaptability of INDELs for amplification ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-011-0588-z
更新日期:2012-07-01 00:00:00
abstract::We present a case of fatal intoxication by the application of a transdermal fentanyl patch upon a superficial bleeding abrasion of a 2-year-old girl. The grandmother discovered the body of the child in bed at approximately 7 a.m. External examination revealed a properly developed, nourished, and hydrated child, with s...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-015-1209-z
更新日期:2015-11-01 00:00:00
abstract::In order to establish a reliable age indicator in the period when all other epiphyseal age indicators have already been inactivated, medial clavicle as the bone with the longest period of growth became the object of various investigations. However, the lack of population-specific method often made it unreliable in som...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-012-0791-6
更新日期:2013-05-01 00:00:00
abstract::During forensic investigations, it is often important to be able to distinguish between impact spatter patterns (blood from gunshots, explosives, blunt force trauma and/or machinery accidents) and bloodstain patterns generated by expiration (blood from the mouth, nose or lungs). These patterns can be difficult to dist...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-010-0498-5
更新日期:2011-11-01 00:00:00
abstract::Biological samples, including skeletal remains exposed to environmental insults for extended periods of time, exhibit increasing levels of DNA damage and fragmentation. Human forensic identification methods typically use a combination of mitochondrial (mt) DNA sequencing and short tandem repeat (STR) analysis, which t...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-019-02110-4
更新日期:2019-09-01 00:00:00
abstract::Projectile impact in sandwich bones typically results in formation of conoidal wounds exhibiting a larger region of damage on the inner cortical plate termed the bevel. To date, a number of hypotheses have been put forward to explain the formation of this wound type. The plug and spall hypothesis suggests that the con...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-019-02086-1
更新日期:2019-09-01 00:00:00
abstract::A short tandem repeat at the D1S1656 locus was sequenced in 45 selected alleles and 13 different alleles were found which were designated according to the total number of repeats. This STR is a compound hypervariable STR consisting of blocks of (TAGR) repeats with a basic sequence structure (TAGA)4(TGA)0-1(TAGA)6-16(T...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140050161
更新日期:1998-01-01 00:00:00
abstract::Limited genetic marker information can be obtained from saliva by typing by conventional serological means. Thus, the application of PCR-based DNA typing methods was investigated as a potential approach for typing genetic markers in saliva. DNA was isolated from 200 cigarettes smoked by 10 different individuals (20 ci...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF01369812
更新日期:1991-01-01 00:00:00
abstract::A 49-year-old white male was found lying unconscious at home. He had vomited, his mouth was filled with a white foam and a pungent odour filled the room. After emergency treatment blood, urine and stomach contents were screened for drugs after acid and alkaline extraction with subsequent derivatisation and GC-MS analy...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140050080
更新日期:1997-01-01 00:00:00
abstract::The in vitro experiments on the interaction of 3H-cocaine and melanin from Sepia officinalis confirmed the existence of drug binding sites on melanin granules. The results suggested that the binding of 3H-cocaine to melanin could be analyzed by assuming that the binding to the surface of pigment granules is analogous ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140050031
更新日期:1997-01-01 00:00:00
abstract::Backspatter is the ejection of biological material from a gunshot entrance wound against the line of fire. This phenomenon was investigated experimentally in transverse gunshots to the heads of calves (n = 9) using two types of 9 mm Parabellum ammunition from shooting distances of 0-10 cm. The resulting bloodstains we...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF01355519
更新日期:1996-01-01 00:00:00
abstract::This paper reports population data and statistics for the HumFES/FPS, HumVWA, HumFGA and D12S391 loci in Austria. The sequences of some rare and new variant alleles which have been identified in the course of the present population study and other investigations are described. Sequence variation occurred in a HumFES/F...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/pl00007712
更新日期:2000-01-01 00:00:00
abstract::A case of traumatic cervical spinal cord injury due to congenital craniocervical abnormalities is described. The autopsy revealed evidence of hyperextension of the neck due to frontal impact, congenital occipitalization of the atlas accompanied by basilar invagination of the odontoid process and atlanto-axial diastasi...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF01225023
更新日期:1993-01-01 00:00:00
abstract::A case of rupture of the superior mesenteric vein with hemoretroperitoneum is described. The autopsy revealed the presence of an acute pancreatitis and thrombosis of the superior mesenteric artery. From the histological findings it appeared that the acute pancreatitis had damaged the venous wall from the outside and t...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF01369553
更新日期:1992-01-01 00:00:00
abstract::The main criteria used in dental age estimation in living young individuals are mineralisation and eruption of the third molars. In order to further diversify the spectrum of characteristics after completion of third molar development, tests were undertaken to determine whether the characteristics studied by Gustafson...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-012-0701-y
更新日期:2012-07-01 00:00:00
abstract:INTRODUCTION:The impact of socioeconomic status (SES) on tooth mineralization has seldom been evaluated. This is important because SES can be used as a proxy for quantifying factors in the environmental that can impact mineralization but that can be difficult to measure directly, such as nutrition. OBJECTIVE:The objec...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-016-1476-3
更新日期:2017-01-01 00:00:00
abstract::The case concerns the sudden death of a 21-year-old male during a soccer game. The autopsy revealed large, calcified saccular aneurysms at the origins of both the left anterior descending and the right coronary arteries. Histologically, the wall of the aneurysms was thin and composed of an internal fibro-calcified lay...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140050213
更新日期:1999-01-01 00:00:00
abstract::In cooperation with the Crime Investigation Agency (Landeskriminalamt) of North Rhine-Westphalia, we carried out a study of 150 cases of (suspected) neonaticide dating from 1993 to 2007 from all over Germany. The autopsy reports and additional expert opinions (if performed) were evaluated for a minimum of 78 variables...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-013-0841-8
更新日期:2013-05-01 00:00:00
abstract::Genetic diversity indices and forensic parameters at 20 autosomal short tandem repeat (STR) loci were evaluated in 541 unrelated individuals of north-western Indian state Rajasthan. In total, 243 alleles were observed with an average of 12.15 alleles per locus. The most polymorphic and discriminative locus was Penta E...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-020-02330-z
更新日期:2020-06-05 00:00:00
abstract::In this study, the effect of sample purification on total signal intensities of samples amplified with genRES MPX-2 (nine-locus multiplex) prior to capillary electrophoretic analysis has been investigated. Sample purification with the Qiaquick PCR purification kit led to an increase of the relative fluorescent signal ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-001-0277-4
更新日期:2002-06-01 00:00:00
abstract::The smoking cessation agent varenicline acts as a partial agonist on α(4)β(2) nicotinic acetylcholine receptors. Although debated, several reports have linked varenicline therapy to an increased risk of suicidal thoughts and/or suicide. In addition, several non-fatal overdose cases have been reported. In this report, ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-012-0695-5
更新日期:2013-01-01 00:00:00