Abstract:
:A short tandem repeat at the D1S1656 locus was sequenced in 45 selected alleles and 13 different alleles were found which were designated according to the total number of repeats. This STR is a compound hypervariable STR consisting of blocks of (TAGR) repeats with a basic sequence structure (TAGA)4(TGA)0-1(TAGA)6-16(TAGG)0-1(TG)5. The presence of a TGA, probably due to an A deletion in the fifth TAGA repeat leads to intermediate a.3 alleles. Population data showed that this is a highly polymorphic STR with a heterozygosity of more than 0.89. This fact together with its simple structure and small size (129-168 bp) makes this STR one of the most interesting DNA polymorphisms for forensic and genetic purposes.
journal_name
Int J Legal Medjournal_title
International journal of legal medicineauthors
Lareu MV,Barral S,Salas A,Pestoni C,Carracedo Adoi
10.1007/s004140050161subject
Has Abstractpub_date
1998-01-01 00:00:00pages
244-7issue
5eissn
0937-9827issn
1437-1596journal_volume
111pub_type
杂志文章abstract::Contrary to the traditional dogma of being a relatively invariable and quiescent organ lacking the capability to regenerate, there is now widespread evidence that the human brain harbors multipotent neural stem cells, possibly throughout senescence. These cells can divide and give rise to neuroectodermal progeny in vi...
journal_title:International journal of legal medicine
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