Abstract：
:The analysis of a mixed biological stain by means of highly polymorphic VNTR systems usually reveals a profile composed of multiple alleles. If the victim and one or several suspects match the profile the evidential strength of the matches has to be very carefully analysed. The appropriate methods for the statistical analysis of DNA profiles advanced recently by Weir with coauthors and by the present authors are limited to cases where all non-tested persons involved in the analysis belong to the same ethnic group. The present paper extends the theory beyond this limitation.
journal_name
Int J Legal Medjournal_title
International journal of legal medicineauthors
Fukshansky N,Bär Wdoi
10.1007/s004140050019subject
Has Abstractpub_date
1999-01-01 00:00:00pages
383-7issue
6eissn
0937-9827issn
1437-1596pii
91120383.414journal_volume
112pub_type
杂志文章abstract：:P-glycoprotein (P-gp), encoded by the ABCB1/MDR1 gene, is a drug transporter at the blood-brain barrier. Several polymorphisms in the ABCB1 gene are known to affect the activity and/or expression of P-gp, thereby influencing the treatment response and toxicity of P-gp substrates like citalopram and venlafaxine. In thi...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-013-0849-0
更新日期：2013-05-01 00:00:00
abstract：:In sauna-associated deaths, the vitality of heat exposure is of great importance. Two case reports address this. First, we present the case of a 77-year-old man who was found dead in the sauna of his family home. When found, the sauna door was closed, and the sauna indicated a temperature of 78 °C. The body had alread...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-021-02504-3
更新日期：2021-01-14 00:00:00
abstract：:Biological samples, including skeletal remains exposed to environmental insults for extended periods of time, exhibit increasing levels of DNA damage and fragmentation. Human forensic identification methods typically use a combination of mitochondrial (mt) DNA sequencing and short tandem repeat (STR) analysis, which t...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-019-02110-4
更新日期：2019-09-01 00:00:00
abstract：:As a contribution to the geographic coverage of EMPOP, currently the best available forensic mitochondrial DNA (mtDNA) database, a total of 299 Swedish individuals were analysed by sequencing of the first and second hypervariable regions of the mtDNA genome. In this sample set, a total of 179 different haplotypes were...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-013-0908-6
更新日期：2013-11-01 00:00:00
abstract：:The recovery of DNA from teeth is usually associated with the destruction of the evidential tooth using, for instance a special grinding mill. In some cases, however, a minimal invasive method of DNA retrieval with a high recovery is required particularly when historical material has to be investigated. A tooth attrib...
journal_title：International journal of legal medicine
pub_type： 传,历史文章,杂志文章
doi：10.1007/s00414-002-0336-5
更新日期：2003-04-01 00:00:00
abstract：:Most standard procedures for extracting DNA from forensic substrates involve manipulations that expose the sample to potential contamination and which reduce yields. Furthermore, most methods require centrifugation and/or solvent extraction steps that render them difficult to automate. We describe a simple closed-tube...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-003-0400-9
更新日期：2003-12-01 00:00:00
abstract：:The original version of this article contained an author name error. In this article, Katrina Madella has been corrected to Katrina Maddela. ...
journal_title：International journal of legal medicine
pub_type： 杂志文章,已发布勘误
doi：10.1007/s00414-019-02031-2
更新日期：2019-05-01 00:00:00
abstract：:We measured the quantity of D-aspartic acid (degree of racemization of aspartic acid) in the enamel of different types of teeth from the same individual. We studied the correlation between the degree of racemization and the time of formation of each particular tooth, as well as the applicability of the degree of racem...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-004-0506-8
更新日期：2005-03-01 00:00:00
abstract：:The question of whether an individual has reached the age of 18 is of crucial importance in forensic age estimation practice. In some countries, the age threshold of 21 years is relevant as well. A completed mineralization of third molars is not a sufficient criterion for a diagnosis of a minimum age of 18 years with ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-009-0415-y
更新日期：2010-05-01 00:00:00
abstract：:Performance of PowerPlex Fusion 6C kit (PP F6C) was assessed in 374 unrelated individuals belonging to Madhya Pradesh, an Indian state. The study evaluated the forensic parameters for the loci included in PP F6C Multiplex System. The combined discrimination power (CPD) and combined exclusion power (CPE) were 1 and 0.9...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-019-02017-0
更新日期：2019-05-01 00:00:00
abstract：:Brazilian population derives from Native Amerindians, Europeans, and Africans. Southeastern Brazil is the most populous region of the country. The present study intended to characterize the maternal genetic ancestry of 290 individuals from southeastern (Brazil) population. Thus, we made the sequencing of the three hyp...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-014-1023-z
更新日期：2014-07-01 00:00:00
abstract：:In this study, a total of 191 cases with STR exclusions out of 591 paternity cases were analysed using 2 STR sets, i.e. (set a) 5 STRs in 462 cases with 150 exclusions and (set b) 9 STRs in 129 cases with 41 exclusions. Set (a) was associated with four exclusions on average while set (b) showed five exclusionary loci ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140000174
更新日期：2001-01-01 00:00:00
abstract：:In kinship analysis, large data sets with estimated haplotype frequencies for marker clusters are very important for the likelihood calculation. Practical use of the X-STRs demonstrated that in some complex kinship cases, the marker set of the Investigator Argus X-12 kit can be insufficient. This study aimed to extend...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-020-02306-z
更新日期：2020-11-01 00:00:00
abstract：:Hereditary hemochromatosis (HH) is a frequent autosomal recessive disease which causes iron-overload of various organs. Of all northern European affected individuals, 90-95% show 1 of 3 known point mutations in the HFE gene. Symptoms and organs involved can vary considerably: Only a small fraction of the 200,000-400,0...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-004-0451-6
更新日期：2004-06-01 00:00:00
abstract：:(-)-Δ-9-tetrahydrocannabinol ((-)-Δ-9-THC) is the main psychoactive constituent in cannabis. During phase I metabolism, it is metabolized to (-)-11-hydroxy-Δ-9-tetrahydrocannabinol ((-)-11-OH-Δ-9-THC), which is psychoactive, and to (-)-11-nor-9-carboxy-Δ-9-tetrahydrocannabinol ((-)-Δ-9-THC-COOH), which is psychoinacti...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-020-02387-w
更新日期：2020-11-01 00:00:00
abstract：:Short tandem repeat (STR) polymorphisms have been extensively used in forensic genetics analysis. Knowledge about the locus-specific mutation rates of STRs improves forensic probability calculations and interpretations of diversity data. To incorporate single-locus diversity information into autosomal STR mutation rat...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-011-0642-x
更新日期：2013-01-01 00:00:00
abstract：BACKGROUND:As sex estimation is an important step to delineate the biological profile, the development of tools employing anatomical structures which may maintain their integrity even after extreme events, such as the maxillary sinus, become useful for forensic identification. Thus, the aim in the present study was to ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-018-1869-6
更新日期：2019-07-01 00:00:00
abstract：:The Ion AmpliSeq™ HID single nucleotide polymorphism (SNP) panel, a primer pool of 103 autosomal SNPs and 33 Y-SNPs, was evaluated using the Ion 314™ Chip on the Ion PGM™ Sequencer with four DNA samples. The study focused on the sequencing of DNA at three different initial target quantities, related interpretation iss...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-013-0879-7
更新日期：2013-11-01 00:00:00
abstract：:Recent studies show that ethyl glucuronide (EtG) can be decomposed by bacteria; whilst so far no degradation of ethyl sulphate (EtS) has been observed. In the present study, in vitro experiments with bacterial colonies were performed. Bacteria (Escherichia coli, Klebsiella pneumoniae, Clostridium sordellii) were isola...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-008-0229-3
更新日期：2008-09-01 00:00:00
abstract：:Diagnosis of ischaemia-related sudden cardiac death in the absence of microscopic and macroscopic ischaemic lesions remains a challenge for medical examiners. Medical imaging techniques increasingly provide support in post-mortem examinations by detecting and documenting internal findings prior to autopsy. Previous st...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-019-02211-0
更新日期：2020-03-01 00:00:00
abstract：:One of the most common conditions during fetal development is anencephaly, which often involves many identification difficulties in the context of physical anthropology, as it causes severe skull challenges. In this paper, we describe the alterations found in the skulls of two perinatal individuals with anencephaly fr...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-014-1123-9
更新日期：2015-07-01 00:00:00
abstract：:Blunt thoracic aortic injury (BTAI) resulting from cardiopulmonary resuscitation (CPR) is rarely reported and most reports are of aortic rupture. Clinical reports have also documented aortic dissection and intramural hematomas with sequential imaging showing the development of these aortic injuries after the administr...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-016-1377-5
更新日期：2016-11-01 00:00:00
abstract：:In the immigration case cited by Jeffreys et al. (1985), the biostatistical evaluation of blood group findings in 16 systems and of HLA-A,B findings for the mother and child, using a special kinship algorithm developed by Ihm and Hummel (1975), produced a probability of maternity of the Ghanaian-born putative mother o...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/BF01371238
更新日期：1992-01-01 00:00:00
abstract：:Organophosphorus insecticides, such as parathion-ethyl, quinalphos, chlorpyrifos, chlorfenvinphos or diazinon, are still widely used for pest control on crops. These compounds are extremely toxic to humans, and, even though specific legislation exists that controls the use of these substances, the frequency of toxic a...
journal_title：International journal of legal medicine
pub_type： 杂志文章,评审
doi：10.1007/s00414-019-02119-9
更新日期：2019-11-01 00:00:00
abstract：:Scars of human skin can on occasions provide a very useful ancillary method of identification of an unknown deceased. If the age of any visible scars can be estimated objectively, then this might be of some assistance in the identification procedure. Melanocytes migrate into scar tissue as it ages and their number wit...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140100225
更新日期：2001-10-01 00:00:00
abstract：:Many studies related to three-dimensional facial reconstruction have been previously reported. On the other hand, no extensive work has been found in the literature about hand reconstruction as an identification method. In this paper, the feasibility of virtual reconstruction of hand skin based on (1) its skeleton and...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-007-0204-4
更新日期：2007-11-01 00:00:00
abstract：:Identification of unknown bodies is mainly made by dental examination and comparison with accurate dental records. Therefore it is necessary to examine the jaws carefully and to locate every tooth-coloured dental restoration. Overlooking dental fillings can make positive identification impossible. The technique descri...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140050138
更新日期：1998-01-01 00:00:00
abstract：:To better characterize the morphologic changes in electrocution, morphologic changes in the hearts of 21 subjects, who died instantaneously of electrocution, were compared to the hearts of decedents with different types of death. Sixteen myocardial samples per heart were processed for histological examination, and sec...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-005-0011-8
更新日期：2006-03-01 00:00:00
abstract：:Stabbing with a kitchen knife is a common method of homicide in Europe. Serrated knives may leave tool markings (striations) in tissues. Documentation of striations is necessary for their use as forensic evidence. Traditional methods (physical casting and photography) have significant limitations, and micro-computed t...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-017-1715-2
更新日期：2018-03-01 00:00:00
abstract：:Few studies have examined the biomechanical basis for backspatter from cranial gunshot wounds. Backspatter is material which travels against the direction of fire following ejection from a gunshot entrance wound. Our paper focuses on the use of animals for reconstructing this phenomenon. Five live pigs and several sla...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-015-1219-x
更新日期：2016-07-01 00:00:00
