Abstract:
:Recent studies show that ethyl glucuronide (EtG) can be decomposed by bacteria; whilst so far no degradation of ethyl sulphate (EtS) has been observed. In the present study, in vitro experiments with bacterial colonies were performed. Bacteria (Escherichia coli, Klebsiella pneumoniae, Clostridium sordellii) were isolated from autopsy material (liver, heart blood, urine, ascites, pericardial fluid, pleural fluid) tested for beta-glucuronidase activity, and three bacterial strains were added to nutrient-deficient medium containing EtG and/or EtS and incubated at 36 +/- 1 degrees C. Samples were taken after various intervals up to 11 days, and EtG and EtS were determined by electrospray ionisation tandem mass spectrometry (LC-ESI-MS/MS). EtG was degraded by E. coli and C. sordellii--complete degradation occurred in the range of 3-4 days--and these bacteria exhibited beta-glucuronidase activity. EtS was not affected within 11 days of incubation.
journal_name
Int J Legal Medjournal_title
International journal of legal medicineauthors
Baranowski S,Serr A,Thierauf A,Weinmann W,Grosse Perdekamp M,Wurst FM,Halter CCdoi
10.1007/s00414-008-0229-3subject
Has Abstractpub_date
2008-09-01 00:00:00pages
389-93issue
5eissn
0937-9827issn
1437-1596journal_volume
122pub_type
杂志文章abstract::Anthropologists are constantly seeking to improve methods for age estimation in the human skeleton. A new method was introduced about a decade ago that assesses the morphological changes that take place in the acetabulum as an individual ages. The pelvis is usually well preserved in forensic cases, which makes this me...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-015-1299-7
更新日期:2016-05-01 00:00:00
abstract:OBJECTIVE:To elucidate postmortem computed tomography (PMCT) and postmortem magnetic resonance (PMMR) imaging findings suggesting massive fat embolism. MATERIALS AND METHODS:Consecutive forensic cases with PMCT and PMMR scans of subjects prior to autopsy were assessed. For PMCT, 16- or 64-row multidetector CT scans we...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-019-02128-8
更新日期:2020-03-01 00:00:00
abstract::The semi-quantitative analysis of decomposed bone of rats exposed to colchicine and euthanized following different time intervals postexposure (i.e., dose-death interval, DDI) is described. Rats received colchicine (50 mg/kg, i.p.) and were euthanized 30 min (DDI1; n = 4), 60 min (DDI2; n = 4), or 180 min (DDI3; n = 4...
journal_title:International journal of legal medicine
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doi:10.1007/s00414-015-1196-0
更新日期:2016-03-01 00:00:00
abstract::The likelihood ratio is the fundamental quantity that summarizes the evidence in forensic cases. Therefore, it is important to understand the theoretical properties of this statistic. This paper is the last in a series of three, and the first to study linked markers. We show that for all non-inbred pairwise kinship co...
journal_title:International journal of legal medicine
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更新日期:2016-11-01 00:00:00
abstract::In this study the development of a 13-locus multiplex-PCR system fitting the updated demands for paternity testing in Germany is described. For this purpose an existing multiplex PCR system that allows the simultaneous amplification of eight different STR loci together with the sex-specific locus amelogenin ( genRESMP...
journal_title:International journal of legal medicine
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doi:10.1007/s00414-003-0420-5
更新日期:2004-02-01 00:00:00
abstract::It is difficult to carry out toxicological investigations in biological samples collected from extensively decomposed bodies and to interpret obtained results as several pitfalls should be considered: redistribution phenomena, degradation of xenobiotics during the postmortem period, contamination by putrefaction fluid...
journal_title:International journal of legal medicine
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journal_title:International journal of legal medicine
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journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-016-1514-1
更新日期:2017-05-01 00:00:00
abstract::The systemic distribution of kerosene components in blood and tissues was analysed in rats following dermal exposure. Four types of trimethylbenzenes (TMBs) and aliphatic hydrocarbons (AHCs) with carbon numbers 9-16 (C(9)-C(16)) were analysed as major kerosene components by capillary gas chromatography/mass spectromet...
journal_title:International journal of legal medicine
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更新日期:2002-08-01 00:00:00
abstract::Five short tandem repeat (STR) systems HumVWA, HumTH01, HumCD4, HumF13B and HumFES were investigated in 2 subpopulations living in Turkey (Laz Turks and Kurds). The population genetic data were compared to a Turkish population sample from the Adana area. A closer genetic relationship was found to the Laz Turks than to...
journal_title:International journal of legal medicine
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更新日期:1997-01-01 00:00:00
abstract::The authors report on a young boy who was bitten into his face by an unknown animal while being asleep in a tent. Given the bite marks and the location of the scene, members of the mustelidae and canidae families were the first "suspects." Deoxyribunucleic acid (DNA) recovered from the tent's wall was analyzed with re...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-012-0674-x
更新日期:2012-05-01 00:00:00
abstract::In the past, numerous studies have documented the possibility of intraindividual differing appearances of the paired age-marker "medial clavicular ossification" in borderline adults. However, the extent of the divergences is rarely mentioned. Against that the article describes this phenomenon from a large sample of 25...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-017-1694-3
更新日期:2018-03-01 00:00:00
abstract::The measurement of the myeloperoxidase activity was used to quantify the acute granulocyte reaction. A 35% loss of blood resulted in a clear decrease of the myeloperoxidase activity at the edges of experimental incision wounds in rat skin in the first day after inflicting the wounds. After 12 h only about one-third an...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140050101
更新日期:1998-01-01 00:00:00
abstract::Allele frequencies for 15 autosomal STR loci (N = 290) and haplotype data for 17 Y-STR loci (N = 157) were determined for an admixed population from Belize. There were no detectable departures from Hardy-Weinberg equilibrium expectations at any autosomal STR loci except for the D8S1179 locus (p = 0.002). The combined ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-014-1082-1
更新日期:2015-11-01 00:00:00
abstract::In Japan and elsewhere, ABO genotyping is frequently used in forensic practice for identification of a decomposed body. However, the phenotype deduced from the genotyping data is occasionally inconsistent with the real phenotype. In this paper, we report a simple ABO genotyping method in which five single nucleotide p...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-006-0148-0
更新日期:2008-01-01 00:00:00
abstract::Necrophagous blow fly larvae can provide accurate estimates of the minimum postmortem interval in death investigations. During larval development, predictable morphological changes occur and measurements of weight, length, and width are compared to species-specific growth curves for reliable age estimates. However, ag...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-012-0699-1
更新日期:2013-01-01 00:00:00
abstract::In the present study, blood samples of 984 unrelated Han individuals were collected from Dongfang, Southern China, after informed consent. A total of 29 Y-chromosomal short tandem repeat (Y-STR) were analyzed, including DYF387S1, DYS19, DYS385ab, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS437, DYS438, DYS43...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-018-1899-0
更新日期:2019-07-01 00:00:00
abstract::CT scan coupled with autopsy is the gold standard for the forensic investigation of fatal road traffic accidents. The objective of the present paper is to demonstrate that from this, it is possible to reconstruct elements of an accident with minimal human and material resources using basic knowledge of three-dimension...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-012-0789-0
更新日期:2013-09-01 00:00:00
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pub_type: 杂志文章
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更新日期:2009-09-01 00:00:00
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journal_title:International journal of legal medicine
pub_type: 杂志文章
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更新日期:2012-03-01 00:00:00
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journal_title:International journal of legal medicine
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更新日期:2020-05-01 00:00:00
abstract::Military rifle bullets are assumed to tumble 180 degrees in the target and end up facing backwards, but intact. It has been claimed, however, that a German version of the 7.62 mm x 51 (7.62 mm NATO) bullet may fragment at ranges up to 100 m. A lack of strength in the jacket, causing it to break at the cannelure when h...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF01369906
更新日期:1995-01-01 00:00:00
abstract::Using AGCU Y24 Plus PCR Amplification Kit, 32 Y short tandem repeat (STR) loci were analyzed in 355 unrelated male participants of Meizhou city in Guangdong Province of China. By analyzing 341 different haplotypes, it was found that haplotype diversity (HD) and discrimination capacity (DC) were 0.9995 and 0.9605, resp...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-018-1845-1
更新日期:2019-03-01 00:00:00
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journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF01428409
更新日期:1995-01-01 00:00:00
abstract::The formation of skull fractures is an important topic in legal medicine. In particular, the influence of boundary conditions is controversially discussed in the literature. A study focusing solely on this aspect was missing. This study aimed to investigate the influence of boundary conditions on the energy threshold ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-019-02023-2
更新日期:2020-03-01 00:00:00
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journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-020-02444-4
更新日期:2021-01-01 00:00:00
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journal_title:International journal of legal medicine
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doi:10.1007/s00414-018-1869-6
更新日期:2019-07-01 00:00:00
abstract::(-)-Δ-9-tetrahydrocannabinol ((-)-Δ-9-THC) is the main psychoactive constituent in cannabis. During phase I metabolism, it is metabolized to (-)-11-hydroxy-Δ-9-tetrahydrocannabinol ((-)-11-OH-Δ-9-THC), which is psychoactive, and to (-)-11-nor-9-carboxy-Δ-9-tetrahydrocannabinol ((-)-Δ-9-THC-COOH), which is psychoinacti...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-020-02387-w
更新日期:2020-11-01 00:00:00
abstract::The utility of postmortem microbiology has continuously been a topic of controversy. The present study describes a case of fatal sepsis in a patient with systemic lupus erythematosus. Postmortem culture and genotyping analyses allowed us to identify Klebsiella pneumoniae as the cause of sepsis, revealing the inadequat...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-015-1160-z
更新日期:2015-09-01 00:00:00
abstract::Organophosphorus insecticides, such as parathion-ethyl, quinalphos, chlorpyrifos, chlorfenvinphos or diazinon, are still widely used for pest control on crops. These compounds are extremely toxic to humans, and, even though specific legislation exists that controls the use of these substances, the frequency of toxic a...
journal_title:International journal of legal medicine
pub_type: 杂志文章,评审
doi:10.1007/s00414-019-02119-9
更新日期:2019-11-01 00:00:00