Postmortem CT and MRI findings of massive fat embolism.

Abstract:

OBJECTIVE:To elucidate postmortem computed tomography (PMCT) and postmortem magnetic resonance (PMMR) imaging findings suggesting massive fat embolism. MATERIALS AND METHODS:Consecutive forensic cases with PMCT and PMMR scans of subjects prior to autopsy were assessed. For PMCT, 16- or 64-row multidetector CT scans were used; for PMMR, a 1.5 T system was used. MRI sequences of the chest area included T2- and T1-weighted fast spin-echo imaging, T2*-weighted imaging, T1-weighted 3-dimensional gradient-echo imaging with or without a fat-suppression pulse, short tau inversion recovery, and in-phase/opposed-phase imaging. At autopsy, forensic pathologists checked for pulmonary fat embolism with fat staining; Falzi's grading system was used for classification. RESULTS:Of 31 subjects, four were excluded because fat staining for histopathological examination of the lung tissue could not be performed. In three of the remaining 27 subjects, histology revealed massive fat embolism (Falzi grade III) and the cause of death was considered to be associated with fat embolism. CT detected a "fat-fluid level" in the right heart or intraluminal fat in the pulmonary arterial branches in two subjects. MRI detected these findings more clearly in both subjects. In one subject, CT and MRI were both negative. There were no positive findings in the 24 subjects that were fat embolism-negative by histology. DISCUSSION AND CONCLUSION:In some subjects, a massive fat embolism can be suggested by postmortem imaging with a "fat-fluid level" in the right heart or intraluminal fat in the pulmonary arterial branches. PMMR potentially suggests fat embolism more clearly than PMCT.

journal_name

Int J Legal Med

authors

Makino Y,Kojima M,Yoshida M,Motomura A,Inokuchi G,Chiba F,Torimitsu S,Hoshioka Y,Yamaguchi R,Saito N,Urabe S,Tsuneya S,Horikoshi T,Yajima D,Iwase H

doi

10.1007/s00414-019-02128-8

subject

Has Abstract

pub_date

2020-03-01 00:00:00

pages

669-678

issue

2

eissn

0937-9827

issn

1437-1596

pii

10.1007/s00414-019-02128-8

journal_volume

134

pub_type

杂志文章
  • Deadly injuries through recoilless anti-tank weapons while military shooting practice-two case studies from Germany and Switzerland.

    abstract::In this casuistry, two accidents from Germany and Switzerland are presented that happened during the shot of recoilless anti-tank weapons. In both cases, the injuries led to the death of two soldiers: A 22-year-old soldier in Germany was struck by the counter mass of a so-called Davis gun which had been fired by a com...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-020-02301-4

    authors: Jellinghaus K,Scherer C,Stauffer E,Urban P,Bohnert M,Kneubuehl BP

    更新日期:2020-11-01 00:00:00

  • Identification and characterization of two novel human polymorphic STRs on the Y chromosome.

    abstract::From sequence database information, we have identified two male-specific and polymorphic tetranucleotide STRs, DYS 441 (GDB:10013873) and DYS 442 (GDB: 10030304), on the Y chromosome. Analysis of 184 males allowed 7 and 5 alleles to be distinguished in the DYS 441 and DYS 442 systems, respectively, yielding 21 haploty...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s004140100207

    authors: Iida R,Tsubota E,Matsuki T

    更新日期:2001-08-01 00:00:00

  • T2 and T2∗ mapping in ex situ porcine myocardium: myocardial intravariability, temporal stability and the effects of complete coronary occlusion.

    abstract::Diagnosis of ischaemia-related sudden cardiac death in the absence of microscopic and macroscopic ischaemic lesions remains a challenge for medical examiners. Medical imaging techniques increasingly provide support in post-mortem examinations by detecting and documenting internal findings prior to autopsy. Previous st...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-019-02211-0

    authors: Webb B,Manninger M,Leoni M,Widek T,Dobrovnik M,Scherr D,Stollberger R,Schwark T

    更新日期:2020-03-01 00:00:00

  • Microbial DNA fingerprinting of human fingerprints: dynamic colonization of fingertip microflora challenges human host inferences for forensic purposes.

    abstract::Human fingertip microflora is transferred to touched objects and may provide forensically relevant information on individual hosts, such as on geographic origins, if endogenous microbial skin species/strains would be retrievable from physical fingerprints and would carry geographically restricted DNA diversity. We tes...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-009-0352-9

    authors: Tims S,van Wamel W,Endtz HP,van Belkum A,Kayser M

    更新日期:2010-09-01 00:00:00

  • Mutation rate estimates for 13 STR loci in a large population from Rio Grande do Sul, Southern Brazil.

    abstract::Short tandem repeat (STR) polymorphisms have been extensively used in forensic genetics analysis. Knowledge about the locus-specific mutation rates of STRs improves forensic probability calculations and interpretations of diversity data. To incorporate single-locus diversity information into autosomal STR mutation rat...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-011-0642-x

    authors: Mardini AC,Rodenbusch R,Schumacher S,Chula FG,Michelon CT,Gastaldo AZ,Maciel LP,de Matos Almeida SE,da Silva CM

    更新日期:2013-01-01 00:00:00

  • Victims of lethal hypothermia have decreased levels of thrombomodulin in myocardium and urine.

    abstract::Severe cold stress has been shown to cause changes in the expression and secretion of thrombomodulin (TM), an endothelial protein regulating haemostasis and inflammation. To further evaluate TM as a cold stress indicator, relative TM mRNA and TM protein levels in the myocardium and the concentrations of TM in serum an...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-014-1138-2

    authors: Pakanen L,Kaija H,Kortelainen ML,Särkioja T,Porvari K

    更新日期:2015-03-01 00:00:00

  • Threshold of the skull injury for blunt force impacts under free and constraint boundary conditions.

    abstract::The formation of skull fractures is an important topic in legal medicine. In particular, the influence of boundary conditions is controversially discussed in the literature. A study focusing solely on this aspect was missing. This study aimed to investigate the influence of boundary conditions on the energy threshold ...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-019-02023-2

    authors: Siegenthaler L,Strehl M,Vaghi A,Zysset P,Kneubuehl BP,Frenz M

    更新日期:2020-03-01 00:00:00

  • Root Pulp Visibility as a mandibular maturity marker at the 18-year threshold in the Maltese population.

    abstract:INTRODUCTION:The determination of age of majority (the 18-year-old threshold) using the popular Demirjian tooth staging method is unreliable, so other maturity markers are required. This study examines whether the Root Pulp Visibility (RPV) of the mandibular third molar is a useful indicator of age. METHODS:One thousa...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-019-02155-5

    authors: Al Qattan F,Alzoubi EE,Lucas V,Roberts G,McDonald F,Camilleri S

    更新日期:2020-01-01 00:00:00

  • Dental age estimation in Somali children using the Willems et al. model.

    abstract:AIM:The aim of the current study was to retrospectively collect dental panoramic radiographs from Somali children living in Finland, to use the radiographic data to develop a new age estimation model based on the model established by Willems et al. (J Forensic Sci 46(4):893-895, 2001), and to compare the age prediction...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-018-1926-1

    authors: Metsäniitty M,Waltimo-Sirén J,Ranta H,Fieuws S,Thevissen P

    更新日期:2018-11-01 00:00:00

  • Characterising the dynamics of expirated bloodstain pattern formation using high-speed digital video imaging.

    abstract::During forensic investigations, it is often important to be able to distinguish between impact spatter patterns (blood from gunshots, explosives, blunt force trauma and/or machinery accidents) and bloodstain patterns generated by expiration (blood from the mouth, nose or lungs). These patterns can be difficult to dist...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-010-0498-5

    authors: Donaldson AE,Walker NK,Lamont IL,Cordiner SJ,Taylor MC

    更新日期:2011-11-01 00:00:00

  • Age estimation in children by measurement of open apices in teeth: an Indian formula.

    abstract::The aim of this paper is twofold: first, to evaluate an Indian sample by Cameriere's European formula; and second, if this formula turns out to be unsuitable, to study a specific formula for Indian children. Orthopantomographs taken from 480 Indian children (227 girls and 253 boys) aged between 3 and 15 years were ana...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-010-0427-7

    authors: Rai B,Kaur J,Cingolani M,Ferrante L,Cameriere R

    更新日期:2010-05-01 00:00:00

  • The Kaiser's tooth.

    abstract::The recovery of DNA from teeth is usually associated with the destruction of the evidential tooth using, for instance a special grinding mill. In some cases, however, a minimal invasive method of DNA retrieval with a high recovery is required particularly when historical material has to be investigated. A tooth attrib...

    journal_title:International journal of legal medicine

    pub_type: 传,历史文章,杂志文章

    doi:10.1007/s00414-002-0336-5

    authors: Pfeiffer H,Benthaus S,Rolf B,Brinkmann B

    更新日期:2003-04-01 00:00:00

  • Multiple suicidal injuries with shotgun slugs.

    abstract::Shotguns are usually used to fire multiple pellets, but they are capable of firing single projectiles. Shotgun slug injuries are rare, severe, and fully comparable to those inflicted by high-velocity projectiles. A case of gunshot suicide of a 59-year-old man with a shotgun loaded with shotgun slugs is presented. The ...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-009-0325-z

    authors: Hejna P

    更新日期:2010-01-01 00:00:00

  • An easily automated, closed-tube forensic DNA extraction procedure using a thermostable proteinase.

    abstract::Most standard procedures for extracting DNA from forensic substrates involve manipulations that expose the sample to potential contamination and which reduce yields. Furthermore, most methods require centrifugation and/or solvent extraction steps that render them difficult to automate. We describe a simple closed-tube...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-003-0400-9

    authors: Moss D,Harbison SA,Saul DJ

    更新日期:2003-12-01 00:00:00

  • Differential gene expression during metamorphosis: a promising approach for age estimation of forensically important Calliphora vicina pupae (Diptera: Calliphoridae).

    abstract::Necrophagous blow fly larvae can provide accurate estimates of the minimum postmortem interval in death investigations. During larval development, predictable morphological changes occur and measurements of weight, length, and width are compared to species-specific growth curves for reliable age estimates. However, ag...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-012-0699-1

    authors: Boehme P,Spahn P,Amendt J,Zehner R

    更新日期:2013-01-01 00:00:00

  • Cardiac pathology in death from electrocution.

    abstract::To better characterize the morphologic changes in electrocution, morphologic changes in the hearts of 21 subjects, who died instantaneously of electrocution, were compared to the hearts of decedents with different types of death. Sixteen myocardial samples per heart were processed for histological examination, and sec...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-005-0011-8

    authors: Fineschi V,Karch SB,D'Errico S,Pomara C,Riezzo I,Turillazzi E

    更新日期:2006-03-01 00:00:00

  • Catalonian population study of the tetranucleotide repeat loci D3S1358, D8S1179, D18S51 and D19S253.

    abstract::Allele frequencies for four short tandem repeat loci were determined in a population sample from Catalonia (NE Spain). After denaturing PAGE electrophoresis, 8 alleles were identified for D3S1358 (n=201), 10 alleles for D8S1179 (n=198), 13 alleles for D18S51 (n=197) and 11 alleles for D19S253 (n=201). No deviation fro...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s004140050205

    authors: Gené M,Piqué E,Borrego N,Carracedo A,Huguet E,Moreno P

    更新日期:1998-01-01 00:00:00

  • Analysis of Y chromosome STR haplotypes in the European part of Russia reveals high diversities but non-significant genetic distances between populations.

    abstract::A total of 17 Y-specific STR loci were studied in 12 districts of the European part of Russia aiming to ascertain the amount of substructure required for the construction of a representative regional database. All groups exhibited high haplotype diversities but low inter-population variance as measured by an analysis ...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-007-0222-2

    authors: Roewer L,Willuweit S,Krüger C,Nagy M,Rychkov S,Morozowa I,Naumova O,Schneider Y,Zhukova O,Stoneking M,Nasidze I

    更新日期:2008-05-01 00:00:00

  • Allele frequencies for 15 autosomal STR loci and haplotype data for 17 Y-STR loci in a population from Belize.

    abstract::Allele frequencies for 15 autosomal STR loci (N = 290) and haplotype data for 17 Y-STR loci (N = 157) were determined for an admixed population from Belize. There were no detectable departures from Hardy-Weinberg equilibrium expectations at any autosomal STR loci except for the D8S1179 locus (p = 0.002). The combined ...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-014-1082-1

    authors: Flores S,Sun J,King J,Eisenberg A,Budowle B

    更新日期:2015-11-01 00:00:00

  • A comparison of 3H-cocaine binding on melanin granules and human hair in vitro.

    abstract::The in vitro experiments on the interaction of 3H-cocaine and melanin from Sepia officinalis confirmed the existence of drug binding sites on melanin granules. The results suggested that the binding of 3H-cocaine to melanin could be analyzed by assuming that the binding to the surface of pigment granules is analogous ...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s004140050031

    authors: Pötsch L,Skopp G,Rippin G

    更新日期:1997-01-01 00:00:00

  • Allele frequencies for 15 STR loci in a population from the Republic of Macedonia.

    abstract::Allele frequencies of 15 STR loci (D8S1179, D21S11, D7S820, CSF1PO, D3S1358, TH01, D13S317, D16S539, D2S1338, D19S433, vWA, TPOX, D18S51, D5S818, and FGA) were determined in a sample of 163 unrelated individuals from the Republic of Macedonia. AmpFISTR Identifiler Kit (Applied Biosystems) was used for PCR amplificatio...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-005-0025-2

    authors: Jakovski Z,Nikolova K,Furac I,Masic M,Janeska B,Kubat M

    更新日期:2006-01-01 00:00:00

  • Blood species discrimination using proton nuclear magnetic resonance spectroscopy.

    abstract::Blood species identification is an important challenge in forensic science. Conventional methods used for blood species analysis are destructive and associated with time-consuming sample preparation steps. Nuclear magnetic resonance (NMR) spectroscopy is known for its nondestructive properties and fast results. This r...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-016-1500-7

    authors: Zailer E,Diehl BW,Monakhova YB

    更新日期:2017-05-01 00:00:00

  • Genetic data for 26 autosomal STR markers from Brazilian population.

    abstract::The allelic frequency distributions and statistical forensic parameters of 26 mini short tandem repeat (mini-STR) loci in a sample of 1575 unrelated individuals from five different Brazilian regions were obtained. All the analyzed loci showed great diversity and were highly informative. The results were compared with ...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-018-1777-9

    authors: Pereira TFC,Malaghini M,Magalhães JCM,Moura-Neto R,Sotomaior VS

    更新日期:2018-09-01 00:00:00

  • Racemization in enamel among different types of teeth from the same individual.

    abstract::We measured the quantity of D-aspartic acid (degree of racemization of aspartic acid) in the enamel of different types of teeth from the same individual. We studied the correlation between the degree of racemization and the time of formation of each particular tooth, as well as the applicability of the degree of racem...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-004-0506-8

    authors: Ohtani S,Ito R,Arany S,Yamamoto T

    更新日期:2005-03-01 00:00:00

  • Reduced CAG repeats length in androgen receptor gene is associated with violent criminal behavior.

    abstract::Androgens mediate their functions through androgen receptors (AR). The two triplet repeats in the AR gene (CAG and GGN) are highly polymorphic among various populations and have been extensively studied in diverse clinical conditions and antisocial personality disorders. Several studies have reported either higher lev...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-008-0225-7

    authors: Rajender S,Pandu G,Sharma JD,Gandhi KP,Singh L,Thangaraj K

    更新日期:2008-09-01 00:00:00

  • Carisoprodol intoxications: a retrospective study of forensic autopsy material from 1992-2003.

    abstract::Carisoprodol is commonly prescribed as a centrally acting muscle relaxant, but it is also subject to abuse. The literature describing fatal intoxications with the drug is limited to a relatively small number of cases, and there are inconsistencies with regard to which concentration levels that are toxic. We therefore ...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-006-0139-1

    authors: Høiseth G,Bramness JG,Christophersen AS,Mørland J

    更新日期:2007-09-01 00:00:00

  • Mitochondrial DNA analysis of Swedish population samples.

    abstract::As a contribution to the geographic coverage of EMPOP, currently the best available forensic mitochondrial DNA (mtDNA) database, a total of 299 Swedish individuals were analysed by sequencing of the first and second hypervariable regions of the mtDNA genome. In this sample set, a total of 179 different haplotypes were...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-013-0908-6

    authors: Lembring M,van Oven M,Montelius M,Allen M

    更新日期:2013-11-01 00:00:00

  • The analysis of temporal gene expression to estimate the age of forensically important blow fly pupae: results from three blind studies.

    abstract::The estimation of the minimum postmortem interval can be implemented by age estimation of corpse-associated primary colonizers such as the blow flies (Diptera: Calliphoridae). In cases where pupae represent the oldest stages found on a body, their age must be added to the duration of prepupal development to estimate t...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-013-0922-8

    authors: Boehme P,Spahn P,Amendt J,Zehner R

    更新日期:2014-05-01 00:00:00

  • Fatal poisonings where ethylmorphine from antitussive medications contributed to death.

    abstract::The hypothesis that antitussives containing ethylmorphine are abused by alcoholics and drug addicts and that this may lead to fatal poisonings where ethylmorphine causes or contributes to death was investigated. For this purpose 14 cases were analysed where a blood ethylmorphine concentration above the therapeutic lev...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s004140050253

    authors: Jonasson B,Jonasson U,Holmgren P,Saldeen T

    更新日期:1999-01-01 00:00:00

  • Lethal ventricular tachycardia triggered after femoral fracture repair in an obese man with insulin-resistant diabetes.

    abstract::An obese man (height, 178 cm; weight, 160 kg; body mass index, 50.5 kg/m2) with a history of recurrent ventricular tachycardia (VT), cardiomyopathy, coronary sclerosis, and insulin-resistant diabetes suffered a right femur fracture in a vehicular accident. His fracture was repaired the following day, but shortly after...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章

    doi:10.1007/s00414-016-1392-6

    authors: Maeda H,Uramatsu M,Nakajima S,Yoshida KI

    更新日期:2016-11-01 00:00:00