Abstract：
:In this study, a total of 191 cases with STR exclusions out of 591 paternity cases were analysed using 2 STR sets, i.e. (set a) 5 STRs in 462 cases with 150 exclusions and (set b) 9 STRs in 129 cases with 41 exclusions. Set (a) was associated with four exclusions on average while set (b) showed five exclusionary loci on average. Double exclusions were observed in 18 cases and further elaborated. Of these, 2 ended up with probabilities of paternity of 0.1% and 0.4%, respectively and with a random occurrence of the hypothesis "mutation" of 1:20,000 and 1:50,000, respectively, while all other cases were associated with much lower frequencies. The conclusion is that the evidential value of a set of highly polymorphic STRs applied in paternity cases is usually extremely high.
journal_name
Int J Legal Medjournal_title
International journal of legal medicineauthors
Brinkmann B,Pfeiffer H,Schürenkamp M,Hohoff Cdoi
10.1007/s004140000174subject
Has Abstractpub_date
2001-01-01 00:00:00pages
173-7issue
3eissn
0937-9827issn
1437-1596journal_volume
114pub_type
杂志文章abstract：:A system of nomenclature is proposed for the complex STR system ACTBP2 (SE33) in order to facilitate data exchange between laboratories. The nomenclature conforms to the ISFH recommendations as far as it is possible for such complex systems. A blind trial was carried out between up to 20 laboratories to ascertain the ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140050124
更新日期：1998-01-01 00:00:00
abstract：:To determine the cause of death in myocardial ion channel diseases (MICD)-induced sudden cardiac death (SCD) cases is a difficulty in forensic identification practices. The majority of MICD-induced SCD cases would experience lethal ventricular tachyarrhythmia (LVTA) before deaths; thus, confirming the occurrence of LV...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-017-1710-7
更新日期：2018-03-01 00:00:00
abstract：:The alcoholism marker CDT was determined on 257 blood samples 1-2 days after the blood samples were taken and again after storage for 7 months at +4 degrees C. The differences between the pairs of CDT values were so large that the determination of CDT after long term storage of the blood sample has no evidential value...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140050013
更新日期：2000-01-01 00:00:00
abstract：:It is difficult to carry out toxicological investigations in biological samples collected from extensively decomposed bodies and to interpret obtained results as several pitfalls should be considered: redistribution phenomena, degradation of xenobiotics during the postmortem period, contamination by putrefaction fluid...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-020-02267-3
更新日期：2020-07-01 00:00:00
abstract：:We measured the quantity of D-aspartic acid (degree of racemization of aspartic acid) in the enamel of different types of teeth from the same individual. We studied the correlation between the degree of racemization and the time of formation of each particular tooth, as well as the applicability of the degree of racem...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-004-0506-8
更新日期：2005-03-01 00:00:00
abstract：:The analysis of a mixed biological stain by means of highly polymorphic VNTR systems usually reveals a profile composed of multiple alleles. If the victim and one or several suspects match the profile the evidential strength of the matches has to be very carefully analysed. The appropriate methods for the statistical ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140050019
更新日期：1999-01-01 00:00:00
abstract：:When blood reaches an extracorporeal surface, a drying process is initiated. Properties of this drying process may be crucial for the correct assessment of case-specific time lapses, however, there is a lack of systematic studies concerning the drying times of blood. We present a study on drying properties of small bl...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-012-0734-2
更新日期：2012-09-01 00:00:00
abstract：:We immunohistochemically examined the intrathrombotic dynamics of autophagy during thrombogenesis using murine deep vein thrombosis (DVT) models. To perform the immunohistochemical analyses, we used anti-LC3 antibody and anti-p62 antibody for detecting the intrathrombotic autophagic functions. We estimated dynamics of...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-019-02168-0
更新日期：2020-05-01 00:00:00
abstract：:Acute aortic dissection (AAD) is a clinically "silent," but emergent and life-threatening cardiovascular disease, and hereditary factors play an important etiologic role in the development of AAD. The purposes of this study are to definitize the diagnostic yield of 59 AAD patients, investigate the molecular pathologic...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-018-1890-9
更新日期：2018-09-01 00:00:00
abstract：:We investigated control and coding region polymorphisms in mitochondrial DNA (mtDNA) in 100 unrelated individuals from a Japanese population and determined the basal phylogenetic haplogroup lineages in all samples under updated information. Many of the basal phylogenetic haplogroup lineages assigned on East Asian mtDN...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-008-0308-5
更新日期：2010-01-01 00:00:00
abstract：:Historically, radiographical identification has been done by comparing conventional antemortem and postmortem X-ray images. The advent of new technologies such as multislice computed tomography (MSCT) is making traditional antemortem examination increasingly less frequent. The authors present the results of MSCT study...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-007-0200-8
更新日期：2007-11-01 00:00:00
abstract：:The goal of the present study is to examine cross-sectional information on the growth of the humerus based on the analysis of four measurements, namely, diaphyseal length, transversal diameter of the proximal (metaphyseal) end of the shaft, epicondylar breadth and vertical diameter of the head. This analysis was perfo...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-012-0713-7
更新日期：2013-01-01 00:00:00
abstract：:To better characterize the morphologic changes in electrocution, morphologic changes in the hearts of 21 subjects, who died instantaneously of electrocution, were compared to the hearts of decedents with different types of death. Sixteen myocardial samples per heart were processed for histological examination, and sec...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-005-0011-8
更新日期：2006-03-01 00:00:00
abstract：:To investigate the genetic variation and forensic efficiency of 19 X-STR loci in the Zhuang and Mulao minorities, we calculated allele frequencies, forensic parameters, and haplotype frequencies of 405 Zhuang and 234 Mulao unrelated healthy individuals from Guangxi Zhuang Autonomous Region of China. Furthermore, we an...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-019-02004-5
更新日期：2020-03-01 00:00:00
abstract：:One of the fundamental questions in forensic medicine and anthropology is whether or not a bone or bone fragment is human. Surprisingly at times for the extreme degradation of the bone (charred, old), DNA cannot be successfully performed and one must turn to other methods. Histological analysis at times can be propose...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-018-1781-0
更新日期：2018-09-01 00:00:00
abstract：OBJECTIVE:To elucidate postmortem computed tomography (PMCT) and postmortem magnetic resonance (PMMR) imaging findings suggesting massive fat embolism. MATERIALS AND METHODS:Consecutive forensic cases with PMCT and PMMR scans of subjects prior to autopsy were assessed. For PMCT, 16- or 64-row multidetector CT scans we...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-019-02128-8
更新日期：2020-03-01 00:00:00
abstract：:Three immunohistochemically different myelomonocytic subtypes, i.e. MRP8, MRP14 and 27E10 were quantitatively evaluated in the intraalveolar, alveolar-interstitial and alveolar-intracapillary lung compartments. Lung sections from 5 major groups with defined causes of death, i.e. drowning and death during immersion (DI...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140050091
更新日期：1997-01-01 00:00:00
abstract：:The identification of species of the forensically important genus Sarcophaga is very difficult and requires strong taxonomic expertise. In this study, we sequenced the mitochondrial cytochrome c oxidase subunit I (COI) gene of 126 specimens of 56 W European Sarcophaga species and added GenBank data to our database to ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-012-0767-6
更新日期：2013-03-01 00:00:00
abstract：:The main criteria used in dental age estimation in living young individuals are mineralisation and eruption of the third molars. In order to further diversify the spectrum of characteristics after completion of third molar development, tests were undertaken to determine whether the characteristics studied by Gustafson...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-012-0701-y
更新日期：2012-07-01 00:00:00
abstract：:This paper considers the statistical evaluation of DNA mixtures in the following situations: (1) two unknown contributors are related respectively to two typed persons, (2) two of the unknown or untyped contributors are related and the third unknown contributor is related to a typed person, or (3) there are two pairs ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-004-0493-9
更新日期：2005-09-01 00:00:00
abstract：:Qualitative information on the sequence composition of the allele and locus structure of the X-STRs DXS8378, DXS9898, DXS6789, GATA31E08, and GATA172D05 was generated in this study. Sequence data were obtained from chimpanzees (Pan troglodytes) and diverse human population groups including Africans, Caucasians, Asians...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-008-0303-x
更新日期：2009-03-01 00:00:00
abstract：:Sequence variation of the hypervariable segments (HVS) I/II of mitochondrial DNA (mtDNA) and the haplogroup affiliation were determined in a sample of 271 Italian subjects. This analysis showed that 42% of the individuals could be ascribed to H, the most frequent haplogroup in European Caucasian populations. This frac...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-005-0059-5
更新日期：2006-05-01 00:00:00
abstract：:Sex estimation is a task of utmost importance in forensic anthropology and bioarcheology. Along with the pelvic bone, the skull is the most important source of sexual dimorphism. On the human skull, the upper third of the face (i.e., the frontal bone) is one of the most significant sexually dimorphic structures useful...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-019-02063-8
更新日期：2019-07-01 00:00:00
abstract：:Bullet velocity is a basic parameter in wound ballistics studies. It is usually measured electronically by means of a variety of solid or photoelectric barriers connected to equipment measuring the time elapsing between impulses, enabling the velocity to be calculated. With the advent of Doppler radar velocity measure...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/BF01247266
更新日期：1994-01-01 00:00:00
abstract：BACKGROUND:The measurement of mast cell tryptase is commonly used to support the diagnosis of anaphylaxis. In the post-mortem setting, the literature recommends sampling from peripheral blood sources (femoral blood) but does not specify the exact sampling technique. Sampling techniques vary between pathologists, and it...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-017-1738-8
更新日期：2018-05-01 00:00:00
abstract：:We developed two multiplex systems for the coamplification of X-chromosomal short tandem repeats (STRs). X-Multiplex 1 consisted of DXS6807, DXS6800, DXS7424, DXS101, GATA172D05 and HPRTB and X-Multiplex 2 consisted of DXS8378, DXS9898, DXS6801, DXS6809, DXS6789, DXS7133, DXS8377 and DXS7423. In addition, we present a...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-011-0629-7
更新日期：2012-03-01 00:00:00
abstract：:One of the most fundamental issues in forensic anthropology is the determination of sex and population affinity based on various skeletal elements. Therefore, we compared the sexual dimorphism of the upper facial skeleton from a recent Czech population (twenty-first century) with that of a population from Early Modern...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-017-1625-3
更新日期：2018-01-01 00:00:00
abstract：:Medico-legal experts are increasingly enlisted to assess the methamphetamine and amphetamine serum concentrations after a criminal offense. However, since criminal users rarely provide useful information to medico-legal experts regarding the substances abused, when the substance(s) was/were used, dose of ingestion too...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-017-1607-5
更新日期：2017-09-01 00:00:00
abstract：:Six synthetic head models wearing ballistic protective helmets were used to recreate two military combat-related shooting incidents (three per incident, designated 'Incident 1' and 'Incident 2'). Data on the events including engagement distances, weapon and ammunition types was collated by the Defence Science and Tech...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-018-1802-z
更新日期：2019-01-01 00:00:00
abstract：:The scope of this study was to evaluate the incidence and the eventual consequences of amniotic fluid aspiration (AFA) in cases of sudden infant death. Cases of sudden infant death syndrome (SIDS; n = 113: 39 females, 74 males; mean age 4.6 months) were compared to a control group of 39 cases of explained death (14 fe...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-009-0384-1
更新日期：2010-03-01 00:00:00
