Abstract:
:The alcoholism marker CDT was determined on 257 blood samples 1-2 days after the blood samples were taken and again after storage for 7 months at +4 degrees C. The differences between the pairs of CDT values were so large that the determination of CDT after long term storage of the blood sample has no evidential value.
journal_name
Int J Legal Medjournal_title
International journal of legal medicineauthors
Köhler H,West A,Brinkmann Bdoi
10.1007/s004140050013subject
Has Abstractpub_date
2000-01-01 00:00:00pages
121-2issue
2eissn
0937-9827issn
1437-1596journal_volume
113pub_type
杂志文章abstract::A total of 17 Y-specific STR loci were studied in 12 districts of the European part of Russia aiming to ascertain the amount of substructure required for the construction of a representative regional database. All groups exhibited high haplotype diversities but low inter-population variance as measured by an analysis ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-007-0222-2
更新日期:2008-05-01 00:00:00
abstract::We investigated 12 X-chromosomal short tandem repeat (STR) polymorphisms in 283 unrelated Malay individuals (160 males and 123 females) living in and around Kuala Lumpur using the Investigator Argus X-12 kit. Heterozygosity among the present 12 X-STRs showed a distribution of from 55.3 to 93.5 %. The diversity values ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-012-0705-7
更新日期:2012-07-01 00:00:00
abstract::Immunohistochemical investigation of the respiratory tract and lungs of 63 fire victims revealed a statistically significant enhanced expression of heat-shock protein 70 (Hsp70) in the epiglottis, the trachea, and the main and the peripheral bronchi compared with a control group. In the fire victims, a strong expressi...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-006-0105-y
更新日期:2006-11-01 00:00:00
abstract::It is difficult to carry out toxicological investigations in biological samples collected from extensively decomposed bodies and to interpret obtained results as several pitfalls should be considered: redistribution phenomena, degradation of xenobiotics during the postmortem period, contamination by putrefaction fluid...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-020-02267-3
更新日期:2020-07-01 00:00:00
abstract::Hereditary hemochromatosis (HH) is a frequent autosomal recessive disease which causes iron-overload of various organs. Of all northern European affected individuals, 90-95% show 1 of 3 known point mutations in the HFE gene. Symptoms and organs involved can vary considerably: Only a small fraction of the 200,000-400,0...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-004-0451-6
更新日期:2004-06-01 00:00:00
abstract::Gene expression analyses based on messenger RNA (mRNA) profiling require accurate data normalisation. When using endogenous reference genes, these have to be validated carefully. Therefore, we examined the transcript stability of 10 potential reference genes using quantitative real-time polymerase chain reaction: beta...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-010-0433-9
更新日期:2010-09-01 00:00:00
abstract::Recently, Verzeletti et al. (Am J Forensic Med Pathol 31:27-33, 2010) developed a new components method for the estimation of age-at-death from the sternal end of the fourth rib. This approach consists of the assignment of numerical scores for several age-related morphological characteristics, which are then inserted ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-012-0735-1
更新日期:2012-09-01 00:00:00
abstract::This paper deals with the usefulness of dental identification in the case of 28 human burn victims of a bus accident in Spain. Postmortem forensic procedures for identification were used including general external examination, routine photographs and radiographs and complementary biological methods. Dental identificat...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004149900099
更新日期:2000-01-01 00:00:00
abstract::The yaw angle in flight of high velocity bullets has been discussed for a number of years, due to its contribution to the tumbling of the bullet in the target. Since few unclassified reports of contemporary bullets are available, we investigated the yaw angles of the bullets used in the M16A2, G3, AK-47 and AK-74 rifl...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF01225601
更新日期:1994-01-01 00:00:00
abstract::To better characterize the morphologic changes in electrocution, morphologic changes in the hearts of 21 subjects, who died instantaneously of electrocution, were compared to the hearts of decedents with different types of death. Sixteen myocardial samples per heart were processed for histological examination, and sec...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-005-0011-8
更新日期:2006-03-01 00:00:00
abstract::Age estimation in living individuals around the age of 18 years remains a difficult challenge. In this study, the anterior inferior vertebral ring apophysis development of cervical vertebrae C2, C3, and C4 of 496 white and 478 black South African individuals aged between 15 and 22 years was assessed from cephalometric...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-019-02137-7
更新日期:2019-11-01 00:00:00
abstract::The assessment of age at death for identification purposes is a frequent and tough challenge for forensic pathologists and anthropologists. Too frequently, visual assessment of age is performed on well-preserved corpses, a method considered subjective and full of pitfalls, but whose level of inadequacy no one has yet ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-014-1042-9
更新日期:2015-07-01 00:00:00
abstract::A 28-year-old man was shot in the back of the head at close range by a robber who then locked him in a room assuming that he was dead. The man was discovered 2 days later. The entrance wound of the bullet was in the left occipital region and it passed into the periphery of the right temporal lobe, where it lodged. The...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004149900120
更新日期:2000-01-01 00:00:00
abstract::Despite being a common form of abuse, there is a paucity of literature describing shackling and wrist restraint injuries among survivors of torture. Forensic evaluation of alleged wrist restraint/handcuff injuries in survivors of torture presents challenges to the evaluator, especially if the injuries are remote and d...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-020-02451-5
更新日期:2021-01-07 00:00:00
abstract::Genetic data from 21 autosomal insertion-null (INNULs) markers found in the InnoTyper® 21 Human DNA Analysis (InnoGenomics®) was evaluated in 190 unrelated individuals from Andalusia. Allele frequencies and forensic parameters were estimated for the 20 INNULs. All loci were in Hardy-Weinberg equilibrium in the study p...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-019-02044-x
更新日期:2019-09-01 00:00:00
abstract::A short tandem repeat at the D1S1656 locus was sequenced in 45 selected alleles and 13 different alleles were found which were designated according to the total number of repeats. This STR is a compound hypervariable STR consisting of blocks of (TAGR) repeats with a basic sequence structure (TAGA)4(TGA)0-1(TAGA)6-16(T...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140050161
更新日期:1998-01-01 00:00:00
abstract::The accuracy of forensic age estimation based on the chronology of second (M2) and third molar (M3) development was investigated using 2,087 orthopantomograms of Korean men and women aged between 3 and 23 years. The developmental stages of M2s and M3s in these subjects were classified using the criteria of Demirjian. ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-010-0513-x
更新日期:2010-11-01 00:00:00
abstract::We hypothesized that miRNAs present in vitreous humor could be a sort of "biological black box," storing information about physiological and environmental circumstances at death. As a proof of concept, we analyzed the vitreous humor miRNA signature to explore its forensic potential applications, such as determining th...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-012-0811-6
更新日期:2013-05-01 00:00:00
abstract::Brazilian population derives from Native Amerindians, Europeans, and Africans. Southeastern Brazil is the most populous region of the country. The present study intended to characterize the maternal genetic ancestry of 290 individuals from southeastern (Brazil) population. Thus, we made the sequencing of the three hyp...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-014-1023-z
更新日期:2014-07-01 00:00:00
abstract::A 32-year-old patient died of a cerebellar haemorrhage and the blood coagulation analysis before death suggested defective synthesis of vitamin K-dependent clotting factors due to vitamin K deficiency. The post-mortem toxicological examination of different tissues revealed phenprocoumon poisoning as the cause of death...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF01369825
更新日期:1996-01-01 00:00:00
abstract::In a Japanese population study of the D1S80 locus 24 alleles ranging from allele 16 to allele43 were analysed using PCR-RFLP. As two repeat units were found to contain the restriction cleavage site (CCAGG) for EcoRII, we digested the alleles with EcoRII, separated the digested fragments on polyacrylamide gels and stai...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140050146
更新日期:1998-01-01 00:00:00
abstract:PURPOSE:The response to traumatic brain injury (TBI) is complex and induces various biological pathways in all brain regions that contribute to bad outcomes. The cerebellar hypoxia after a frontal cortex injury may potentiate the pathophysiological impacts of TBI. Therefore, a gene expression analysis was conducted to ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-014-1129-3
更新日期:2015-07-01 00:00:00
abstract::We demonstrate the applicability of ion-pair reversed-phase high-performance liquid chromatography-electrospray ionization time-of-flight mass spectrometry (ICEMS) for the simultaneous characterization of length and nucleotide polymorphisms. Two sections within the first (HVS-I) and second (HVS-II) hypervariable segme...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-006-0117-7
更新日期:2007-01-01 00:00:00
abstract::We have studied the correlation between the level of D-aspartic acid in dentin and the period of dentin formation in different types of teeth from the same individual. Except for the third molar, it is generally agreed that the formation of permanent dentin follows the pattern of growth, occurring earliest in the firs...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-003-0365-8
更新日期:2003-06-01 00:00:00
abstract::Paradoxical undressing is a phenomenon characterizing some fatal hypothermia cases. The victims, despite low environmental temperatures, paradoxically remove their clothes due to a sudden feeling of warmth. In this report, we describe a case of suspected paradoxical undressing in a non-hypothermia case. The victim, a ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-017-1597-3
更新日期:2017-09-01 00:00:00
abstract::We developed two multiplex systems for the coamplification of X-chromosomal short tandem repeats (STRs). X-Multiplex 1 consisted of DXS6807, DXS6800, DXS7424, DXS101, GATA172D05 and HPRTB and X-Multiplex 2 consisted of DXS8378, DXS9898, DXS6801, DXS6809, DXS6789, DXS7133, DXS8377 and DXS7423. In addition, we present a...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-011-0629-7
更新日期:2012-03-01 00:00:00
abstract:INTRODUCTION:Electronic control with the CEW (conducted electrical weapon) has gained widespread acceptance as the preferred force option due to its significant injury reduction. However, a CEW application does stress the human body. In the case of the CEW, the human body response is similar to the challenge of physica...
journal_title:International journal of legal medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s00414-018-1771-2
更新日期:2018-09-01 00:00:00
abstract::Backspatter is the ejection of biological material from a gunshot entrance wound against the line of fire. This phenomenon was investigated experimentally in transverse gunshots to the heads of calves (n = 9) using two types of 9 mm Parabellum ammunition from shooting distances of 0-10 cm. The resulting bloodstains we...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF01355519
更新日期:1996-01-01 00:00:00
abstract::Ancestry informative markers (AIMs) can be used to detect and adjust for population stratification and predict the ancestry of the source of an evidence sample. Autosomal single nucleotide polymorphisms (SNPs) are the best candidates for AIMs. It is essential to identify the most informative AIM SNPs across relevant p...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-015-1297-9
更新日期:2016-03-01 00:00:00
abstract::In forensic science, the unequivocal identification of the cellular origin of crime scene samples used for DNA profiling can provide crucial information for crime scene reconstruction. We have previously shown that various mRNA markers from genes with expression patterns specific for blood and saliva can be establishe...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-008-0249-z
更新日期:2009-01-01 00:00:00