Abstract：
:Genetic data from 21 autosomal insertion-null (INNULs) markers found in the InnoTyper® 21 Human DNA Analysis (InnoGenomics®) was evaluated in 190 unrelated individuals from Andalusia. Allele frequencies and forensic parameters were estimated for the 20 INNULs. All loci were in Hardy-Weinberg equilibrium in the study population after Bonferroni correction and showed no signs of linkage between them. The combined power of discrimination and the power of exclusion for the 20 INNULs were 1-7.42352 × 10-9 and 93.60946%, respectively. These data might be useful for the research of population genetics and for individual identification and paternity testing in forensic science.
journal_name
Int J Legal Medjournal_title
International journal of legal medicineauthors
Saiz M,Gutierrez-Carvajal A,Galvez X,Lorente JA,Alvarez JCdoi
10.1007/s00414-019-02044-xsubject
Has Abstractpub_date
2019-09-01 00:00:00pages
1397-1400issue
5eissn
0937-9827issn
1437-1596pii
10.1007/s00414-019-02044-xjournal_volume
133pub_type
杂志文章abstract：:P-glycoprotein (P-gp), encoded by the ABCB1/MDR1 gene, is a drug transporter at the blood-brain barrier. Several polymorphisms in the ABCB1 gene are known to affect the activity and/or expression of P-gp, thereby influencing the treatment response and toxicity of P-gp substrates like citalopram and venlafaxine. In thi...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-013-0849-0
更新日期：2013-05-01 00:00:00
abstract：:A 12-year-old boy with no previous serious medical history experienced abdominal discomfort and chest pains for 5 days and suddenly died. The autopsy revealed diffuse and extensive infiltration of eosinophils into the myocardium, with poorly formed granulomas and few fibrotic changes. The necrotic changes was so exten...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/BF01369797
更新日期：1996-01-01 00:00:00
abstract：:Abstract DNA typing of four tetrameric repeat loci (HUMVWA, HUMTH0I, D21SII and HPRT) was carried out in a Chinese Han population from Shanghai (East China) and one from Guangzhou (South-East China) using a quadruplex PCR amplification and detection of the fluorescent-labeled alleles on the ALF DNA sequencer. All loci...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140050187
更新日期：1998-01-01 00:00:00
abstract：:A population database was generated from 118 unrelated Caucasoid individuals living in Spain. Sequence polymorphisms of the mitochondrial DNA (mtDNA) control region, hypervariable regions I and II (HVRI and HVRII) were determined using the polymerase chain reaction (PCR) and direct sequencing. A total of 102 different...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140000158
更新日期：2000-01-01 00:00:00
abstract：:Suppose that part of the prosecution's evidence in some crime case is analysis of a blood stain, and that the traits E discovered in the stain suggest multiple donors. Then the prosecution will probably allege some specific inculpatory hypothesis H0 about the sources of the stain, and P (E [symbol: see text] H0) can b...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/BF01225523
更新日期：1996-01-01 00:00:00
abstract：:An 89-year-old woman was found dead lying in her bed. Autopsy demonstrated a pronounced thickening of all coronary arteries except for the first 2-4 cm. Death was due to a recent myocardial infarction. Microscopically, the coronary arteries showed a substantial concentric thickening of all three layers with 90% narrow...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-006-0090-1
更新日期：2006-11-01 00:00:00
abstract：:Y-chromosomal short tandem repeats (Y-STRs) are commonly used to study population histories, discover ancestral relationships, and identify males for criminal justice purposes. Y-STRs being largely in forensic use have low haplotype diversity in some populations and cannot discriminate between paternal male relatives....
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-018-01997-9
更新日期：2019-05-01 00:00:00
abstract：:In humans, the amelogenin gene is present on both the X and the Y chromosomes. However, there are size differences in this gene between these chromosomes, which have been utilised for sexing in forensic casework and prenatal diagnosis. Our study using the AmpFl STR Profiler Plus kit, showed a deletion of Y chromosome-...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-001-0262-y
更新日期：2002-04-01 00:00:00
abstract：:The present paper analyses the applicability of the clinically prevalent skeletal age determination method of Tanner and Whitehouse for forensic age estimation in living individuals. For this purpose, the hand X-rays from 48 boys and 44 girls aged 12-16 years were evaluated retrospectively. The minima and maxima, the ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-008-0237-3
更新日期：2008-07-01 00:00:00
abstract：:The case of a man's death as a consequence of an accident with a mountain bike was examined. Despite only slight external injuries, a general examination revealed the existence of a rupture of the diaphragm which was the ultimate cause of death. The discussion reconstructs the way the accident occurred and briefly ana...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140100237
更新日期：2001-12-01 00:00:00
abstract：:A medicolegal/algological collaboration lasting several years aimed at developing methods for dealing with dead bodies found in water where the circumstances are not clear, has led to an interdisciplinary procedure. To enable algological analysis, sample preservation and preparation must be free from contamination or ...
journal_title：International journal of legal medicine
pub_type： 杂志文章,评审
doi：10.1007/s004149900122
更新日期：2000-01-01 00:00:00
abstract：:In many countries, assessment of legal age, also known as age of majority, has become increasingly important over the years. In China, individuals older than 18 years of age have full capacity regarding civil conduct and can be tried as an adult for criminal charges. Therefore, from a legal point of view, it is crucia...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-018-1907-4
更新日期：2018-11-01 00:00:00
abstract：:The systemic distribution of kerosene components in blood and tissues was analysed in rats following dermal exposure. Four types of trimethylbenzenes (TMBs) and aliphatic hydrocarbons (AHCs) with carbon numbers 9-16 (C(9)-C(16)) were analysed as major kerosene components by capillary gas chromatography/mass spectromet...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-001-0282-7
更新日期：2002-08-01 00:00:00
abstract：:The accuracy of forensic age estimation based on the chronology of second (M2) and third molar (M3) development was investigated using 2,087 orthopantomograms of Korean men and women aged between 3 and 23 years. The developmental stages of M2s and M3s in these subjects were classified using the criteria of Demirjian. ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-010-0513-x
更新日期：2010-11-01 00:00:00
abstract：:Cocaine and alcohol toxicity is well known, especially when simultaneously abused. These drugs perform both acute and chronic harmfulness, with significant cardiac events such as ventricular arrhythmias, tachycardia, systemic hypertension, acute myocardial infarction, ventricular hypertrophy, and acute coronary syndro...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-014-1119-5
更新日期：2015-01-01 00:00:00
abstract：:The recovery of DNA from teeth is usually associated with the destruction of the evidential tooth using, for instance a special grinding mill. In some cases, however, a minimal invasive method of DNA retrieval with a high recovery is required particularly when historical material has to be investigated. A tooth attrib...
journal_title：International journal of legal medicine
pub_type： 传,历史文章,杂志文章
doi：10.1007/s00414-002-0336-5
更新日期：2003-04-01 00:00:00
abstract：:This paper deals with the usefulness of dental identification in the case of 28 human burn victims of a bus accident in Spain. Postmortem forensic procedures for identification were used including general external examination, routine photographs and radiographs and complementary biological methods. Dental identificat...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004149900099
更新日期：2000-01-01 00:00:00
abstract：:Despite being a common form of abuse, there is a paucity of literature describing shackling and wrist restraint injuries among survivors of torture. Forensic evaluation of alleged wrist restraint/handcuff injuries in survivors of torture presents challenges to the evaluator, especially if the injuries are remote and d...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-020-02451-5
更新日期：2021-01-07 00:00:00
abstract：:In the forensic anthropology practice, bone diseases are rarely considered for personal identification. In this paper, we present a forensic skeletonized case with tuberculous bone lesions, for which bone pathology may provide an indicator for positive personal identification. Antemortem hospital records were availabl...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-020-02348-3
更新日期：2020-09-01 00:00:00
abstract：:The in vitro experiments on the interaction of 3H-cocaine and melanin from Sepia officinalis confirmed the existence of drug binding sites on melanin granules. The results suggested that the binding of 3H-cocaine to melanin could be analyzed by assuming that the binding to the surface of pigment granules is analogous ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140050031
更新日期：1997-01-01 00:00:00
abstract：:Current analysis of forensic DNA stains relies on the probabilistic interpretation of bulk-processed samples that represent mixed profiles consisting of an unknown number of potentially partial representations of each contributor. Single-cell methods, in contrast, offer a solution to the forensic DNA mixture problem b...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-021-02503-4
更新日期：2021-01-23 00:00:00
abstract：:Androgens mediate their functions through androgen receptors (AR). The two triplet repeats in the AR gene (CAG and GGN) are highly polymorphic among various populations and have been extensively studied in diverse clinical conditions and antisocial personality disorders. Several studies have reported either higher lev...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-008-0225-7
更新日期：2008-09-01 00:00:00
abstract：:A single-tube multiplex assay of a small set of ancestry-informative markers (AIMs) for effectively estimating individual ancestry and admixture is an ideal forensic tool to trace the population origin of an unknown DNA sample. We present a newly developed 27-plex single nucleotide polymorphism (SNP) panel with highly...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-015-1183-5
更新日期：2016-01-01 00:00:00
abstract：:Military rifle bullets are assumed to tumble 180 degrees in the target and end up facing backwards, but intact. It has been claimed, however, that a German version of the 7.62 mm x 51 (7.62 mm NATO) bullet may fragment at ranges up to 100 m. A lack of strength in the jacket, causing it to break at the cannelure when h...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/BF01369906
更新日期：1995-01-01 00:00:00
abstract：:The use of tracker dogs is the main method of finding hidden bodies, and in their search the dogs use typical scent patterns. "Electronic noses" can also be used to find and compare such patterns. Highly sensitive scent detectors have been successfully applied, e.g. in the examination of foodstuffs, in environmental t...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-009-0338-7
更新日期：2010-01-01 00:00:00
abstract：:It is commonly accepted that crime scene recovery and recording are key moments of any judicial inspection in which investigators must decide on the correct strategies to put into place. Complex outdoor scenarios, presenting partially or entirely skeletonised remains, can benefit more than others by the intervention o...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-020-02456-0
更新日期：2020-12-19 00:00:00
abstract：:In this study, a total of 191 cases with STR exclusions out of 591 paternity cases were analysed using 2 STR sets, i.e. (set a) 5 STRs in 462 cases with 150 exclusions and (set b) 9 STRs in 129 cases with 41 exclusions. Set (a) was associated with four exclusions on average while set (b) showed five exclusionary loci ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140000174
更新日期：2001-01-01 00:00:00
abstract：:Inferring an unknown DNA's ancestry using a set of ancestry-informative single nucleotide polymorphisms (SNPs) in forensic science is useful to provide investigative leads. This is especially true when there is no DNA database match or specified suspect. Thus, a set of SNPs with highly robust and balanced differential...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-018-1863-z
更新日期：2019-07-01 00:00:00
abstract：:We present a duo paternity test case to assess the biological relationship between a woman and her female child. After analyzing 57 autosomal and 19 X-chromosomal short tandem repeat loci, mother-daughter exclusions were discovered at four loci, which were all located on chromosome 2. Further testing of whole-genome s...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-018-1857-x
更新日期：2019-07-01 00:00:00
abstract：:The case concerns the sudden death of a 21-year-old male during a soccer game. The autopsy revealed large, calcified saccular aneurysms at the origins of both the left anterior descending and the right coronary arteries. Histologically, the wall of the aneurysms was thin and composed of an internal fibro-calcified lay...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140050213
更新日期：1999-01-01 00:00:00
