Forensic genetic analysis of population of Madhya Pradesh with PowerPlex Fusion 6C™ Multiplex System.

Abstract:

:Performance of PowerPlex Fusion 6C kit (PP F6C) was assessed in 374 unrelated individuals belonging to Madhya Pradesh, an Indian state. The study evaluated the forensic parameters for the loci included in PP F6C Multiplex System. The combined discrimination power (CPD) and combined exclusion power (CPE) were 1 and 0.999999995, respectively, for all 23 autosomal STR loci. SE33 showed the greatest power of discrimination (0.990) in the studied population, whereas TPOX showed the lowest (0.843). The availability of three Y-STR loci in the Multiplex System is suitable for assessing male contribution and amelogenin deletion in a single Multiplex PCR simultaneously. The study also presents the first global report on polymorphism in the Indian population on SE 33 autosomal STR loci and PP Fusion 6C Multiplex System. The results revealed that the studied STR Multiplex System is highly polymorphic and suitable for forensic purposes.

journal_name

Int J Legal Med

authors

Dixit S,Shrivastava P,Kumawat RK,Kaitholia K,Dash HR,Sharma H,Choubey G

doi

10.1007/s00414-019-02017-0

subject

Has Abstract

pub_date

2019-05-01 00:00:00

pages

803-805

issue

3

eissn

0937-9827

issn

1437-1596

pii

10.1007/s00414-019-02017-0

journal_volume

133

pub_type

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