Abstract：
:The tetrameric STRs, HUMTH01, HUMVWA31A and HUMFES/FPS, were studied in a population from the Basque Country (northern Spain) for their frequency distribution and applicability to identity and paternity testing. All systems conformed to Hardy-Weinberg equilibrium; pairwise comparisons demonstrated the allelic independence between loci, and furthermore, all systems seemed to be in agreement with expectations from the Stepwise Mutation Model (SMM) of the mutation-drift theory, which indicates the homogeneity of the population and suggests a replication slippage mechanism as a possible model for generating alleles. A comparison with other population groups appeared to indicate that frequencies are well conserved in Caucasians, but differ from other racial groups. The calculated parameters "a priori probability of exclusion" (PEX) and "index of discrimination" (ID), show the informativeness of these loci for the determination of identity and relatedness of individuals.
journal_name
Int J Legal Medjournal_title
International journal of legal medicineauthors
Alonso S,Castro A,Fernandez I,Gómez de Cedrón M,Garcia-Orad A,Meyer E,Martínez de Pancorbo Mdoi
10.1007/BF01245481subject
Has Abstractpub_date
1995-01-01 00:00:00pages
239-45issue
5eissn
0937-9827issn
1437-1596journal_volume
107pub_type
杂志文章abstract：:The use of DNA to determine the ancestry of an individual is becoming more and more important in the areas of forensics. Kidd et al. (Forensic Sci Int Genet 12:215-224, 2014) have been the first to identify and catalog haplotypes, termed as minihaplotypes (1-10-kilobase spans) and microhaplotypes (≤ 200 bp), with pote...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-018-1881-x
更新日期：2019-07-01 00:00:00
abstract：:Human fingertip microflora is transferred to touched objects and may provide forensically relevant information on individual hosts, such as on geographic origins, if endogenous microbial skin species/strains would be retrievable from physical fingerprints and would carry geographically restricted DNA diversity. We tes...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-009-0352-9
更新日期：2010-09-01 00:00:00
abstract：:The genetic polymorphisms of 15 autosomal short tandem repeat (STR) loci included in the AmpFISTR Sinofiler™ kit were evaluated in 547 healthy unrelated Han individuals from Gansu, China. All of the loci reached the Hardy-Weinberg equilibrium after the Bonferroni correction (p > 0.0033). These loci were examined to de...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-014-1132-8
更新日期：2015-07-01 00:00:00
abstract：:The allelic frequency distributions and statistical forensic parameters of 26 mini short tandem repeat (mini-STR) loci in a sample of 1575 unrelated individuals from five different Brazilian regions were obtained. All the analyzed loci showed great diversity and were highly informative. The results were compared with ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-018-1777-9
更新日期：2018-09-01 00:00:00
abstract：:Current analysis of forensic DNA stains relies on the probabilistic interpretation of bulk-processed samples that represent mixed profiles consisting of an unknown number of potentially partial representations of each contributor. Single-cell methods, in contrast, offer a solution to the forensic DNA mixture problem b...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-021-02503-4
更新日期：2021-01-23 00:00:00
abstract：:The Ion AmpliSeq™ HID single nucleotide polymorphism (SNP) panel, a primer pool of 103 autosomal SNPs and 33 Y-SNPs, was evaluated using the Ion 314™ Chip on the Ion PGM™ Sequencer with four DNA samples. The study focused on the sequencing of DNA at three different initial target quantities, related interpretation iss...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-013-0879-7
更新日期：2013-11-01 00:00:00
abstract：:This study reports mtDNA polymorphisms in both hypervariable segments HV1 and HV2 of the non coding D-loop region from 60 unrelated Koreans. In contrast to two previous Korean data base studies, mtDNA was extracted separately from pulp tissue and root dentin of teeth obtained from dentists. Dentin turned out to be a r...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140050177
更新日期：1998-01-01 00:00:00
abstract：:The brains of 70 fatal cases with AIDS were studied by means of immunohistochemistry and in-situ hybridization in a consecutive autopsy series (1985-July 1992). In addition, the neuropathological changes were correlated with the neurological and neuroimaging findings. Opportunistic infections included toxoplasmosis (1...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/BF01222119
更新日期：1993-01-01 00:00:00
abstract：:A cross-sectional study was carried out to assess chronological age estimation based on the stages of third lower molar development, following the eight stages (A-H) method of Demirjian et al. The final sample consisted of 1,054 orthopantomograms from Spanish individuals of known chronological age (range 14-21 years) ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-005-0530-3
更新日期：2005-11-01 00:00:00
abstract：:STR-based individualisation of biological deposits on bullets after perforation of tissue, can identify the person injured or killed by a particular bullet and comparison with the firearms used can identify the weapon and thus possibly the person who did the shooting. In this study, the effect of subsequent impacts on...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140000203
更新日期：2001-01-01 00:00:00
abstract：:The recovery of DNA from teeth is usually associated with the destruction of the evidential tooth using, for instance a special grinding mill. In some cases, however, a minimal invasive method of DNA retrieval with a high recovery is required particularly when historical material has to be investigated. A tooth attrib...
journal_title：International journal of legal medicine
pub_type： 传,历史文章,杂志文章
doi：10.1007/s00414-002-0336-5
更新日期：2003-04-01 00:00:00
abstract：:Kinship relation and, in particular, paternity probability estimation using a Bayesian approach require the input of a priori probabilities of different hypotheses. In practical case work, a priori probabilities or priors, for short, must often be estimated using only common sense and symmetry arguments because in mos...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-013-0827-6
更新日期：2013-11-01 00:00:00
abstract：:Multiple tooth development staging techniques were reported based on arbitrarily set borderlines between succeeding stages. Anatomic tooth features or predictions of future tooth part dimensions were described to identify the thresholds between the established stages. The need to predict mature tooth dimensions, while...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-014-1011-3
更新日期：2015-01-01 00:00:00
abstract：:Speckle interferometry is a non-destructive measurement technique using a laser. The principles of the method are described. Human hyoid bones (n = 10) were investigated. Loads were applied to individual points on the anterior surface of the body of hyoid bones. All hyoid bones showed an asymmetric displacement. The d...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/BF01225233
更新日期：1993-01-01 00:00:00
abstract：:Methadone plays an increasing role in drug-related deaths in Hamburg. To find out whether intravenous application of methadone plays a relevant role in methadone-related deaths, body fluids of all methadone-positive cases (n=130) and three buprenorphine-positive cases where a urine sample was available (n=58+3) were i...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-014-1017-x
更新日期：2014-09-01 00:00:00
abstract：:Few studies have examined the biomechanical basis for backspatter from cranial gunshot wounds. Backspatter is material which travels against the direction of fire following ejection from a gunshot entrance wound. Our paper focuses on the use of animals for reconstructing this phenomenon. Five live pigs and several sla...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-015-1219-x
更新日期：2016-07-01 00:00:00
abstract：:To increase the reliability of forensic age estimations in living adolescents and young adults where there is no legitimation for X-ray examinations, it would be desirable to establish radiation-free imaging methods. In the present study, the ossification stage of the distal femoral epiphysis was determined retrospect...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-014-0967-3
更新日期：2014-05-01 00:00:00
abstract：:The purpose of this study is to evaluate allelic association and linkage of 18 adjacent syntenic short tandem repeat (STR) pairs form out of 30 markers located on 12 different autosomes. Linkage disequilibrium was tested by using the unknown gametic phase genotypes and phased haplotypes from 290 unrelated individuals ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-014-1032-y
更新日期：2014-09-01 00:00:00
abstract：:The problems of testing patients or the deceased using classical blood group systems for identity or paternity purposes after multiple transfusions are well known. In a paternity case where the putative father received multiple transfusions it was possible to determine some classical blood group systems. The investiga...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/BF01371333
更新日期：1994-01-01 00:00:00
abstract：:A 49-year-old white male was found lying unconscious at home. He had vomited, his mouth was filled with a white foam and a pungent odour filled the room. After emergency treatment blood, urine and stomach contents were screened for drugs after acid and alkaline extraction with subsequent derivatisation and GC-MS analy...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140050080
更新日期：1997-01-01 00:00:00
abstract：:One of the fundamental questions in forensic medicine and anthropology is whether or not a bone or bone fragment is human. Surprisingly at times for the extreme degradation of the bone (charred, old), DNA cannot be successfully performed and one must turn to other methods. Histological analysis at times can be propose...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-018-1781-0
更新日期：2018-09-01 00:00:00
abstract：:Military rifle bullets are assumed to tumble 180 degrees in the target and end up facing backwards, but intact. It has been claimed, however, that a German version of the 7.62 mm x 51 (7.62 mm NATO) bullet may fragment at ranges up to 100 m. A lack of strength in the jacket, causing it to break at the cannelure when h...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/BF01369906
更新日期：1995-01-01 00:00:00
abstract：:Recently, Verzeletti et al. (Am J Forensic Med Pathol 31:27-33, 2010) developed a new components method for the estimation of age-at-death from the sternal end of the fourth rib. This approach consists of the assignment of numerical scores for several age-related morphological characteristics, which are then inserted ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-012-0735-1
更新日期：2012-09-01 00:00:00
abstract：:Crania are a reliable source for sex estimation in Euro-Americans, Europeans, and most other populations. Besides morphological assessments, the application of Fordisc® has become a useful tool within the last two decades, creating discriminant functions from morphometric data. Unfortunately, until now, white populati...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-016-1469-2
更新日期：2017-07-01 00:00:00
abstract：:To study the population data of Y-chromosome STRs (Y-STRs) of Han population resided in Hunan province, we analyzed haplotypes of 26 Y-STRs (DYS19, DYS385a/b, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS437, DYS438, DYS439, DYS448, DYS456, DYS458, DYS481, DYS533, DYS549, DYS570, DYS576, DYS635, DYS643, DYS38...
journal_title：International journal of legal medicine
pub_type： 杂志文章,评审
doi：10.1007/s00414-016-1411-7
更新日期：2017-01-01 00:00:00
abstract：:In this study the development of a 13-locus multiplex-PCR system fitting the updated demands for paternity testing in Germany is described. For this purpose an existing multiplex PCR system that allows the simultaneous amplification of eight different STR loci together with the sex-specific locus amelogenin ( genRESMP...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-003-0420-5
更新日期：2004-02-01 00:00:00
abstract：:We report about the case of a sudden unexpected death of a 25-year-old male suffering from infectious disease. An autopsy was ordered with no final premortem diagnosis. Microscopic and microbiological examination revealed a pneumococcal bronchopneumonia and hemophagocytic lesions in the bone marrow. After integrating ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-015-1305-0
更新日期：2016-05-01 00:00:00
abstract：:We present a case of fatal intoxication by the application of a transdermal fentanyl patch upon a superficial bleeding abrasion of a 2-year-old girl. The grandmother discovered the body of the child in bed at approximately 7 a.m. External examination revealed a properly developed, nourished, and hydrated child, with s...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-015-1209-z
更新日期：2015-11-01 00:00:00
abstract：:DNA-based prediction for externally visible characteristics such as eye color is already a useful tool in forensic criminal investigations. The IrisPlex system, consisting of six single nucleotide polymorphisms (SNPs) and a prediction model, was developed based on individuals from several European populations. Other r...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-013-0953-1
更新日期：2014-05-01 00:00:00
abstract：:A study of the genetic variability in the Chueta (Majorcan Jews) and the Balearic (Majorca and Minorca Islands) populations was carried out using a multiplex system containing the nine tetrameric STRs D3S1358, vWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317 and D7S820. The Chueta population has remained isolated be...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004149900101
更新日期：2000-01-01 00:00:00
