Abstract：
:This study reports mtDNA polymorphisms in both hypervariable segments HV1 and HV2 of the non coding D-loop region from 60 unrelated Koreans. In contrast to two previous Korean data base studies, mtDNA was extracted separately from pulp tissue and root dentin of teeth obtained from dentists. Dentin turned out to be a reliable source of mitochondrial DNA. This can be of practical importance in forensic identification case work after a long post-mortem interval since pulp decomposes rapidly. The extraction method is explained in detail. The mtDNA polymorphisms obtained from 60 teeth of unrelated Koreans were compared with the already existing Korean data base.
journal_name
Int J Legal Medjournal_title
International journal of legal medicineauthors
Pfeiffer H,Steighner R,Fisher R,Mörnstad H,Yoon CL,Holland MMdoi
10.1007/s004140050177subject
Has Abstractpub_date
1998-01-01 00:00:00pages
309-13issue
6eissn
0937-9827issn
1437-1596journal_volume
111pub_type
杂志文章abstract：:Most standard procedures for extracting DNA from forensic substrates involve manipulations that expose the sample to potential contamination and which reduce yields. Furthermore, most methods require centrifugation and/or solvent extraction steps that render them difficult to automate. We describe a simple closed-tube...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-003-0400-9
更新日期：2003-12-01 00:00:00
abstract：:Using AGCU Y24 Plus PCR Amplification Kit, 32 Y short tandem repeat (STR) loci were analyzed in 355 unrelated male participants of Meizhou city in Guangdong Province of China. By analyzing 341 different haplotypes, it was found that haplotype diversity (HD) and discrimination capacity (DC) were 0.9995 and 0.9605, resp...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-018-1845-1
更新日期：2019-03-01 00:00:00
abstract：:To examine the prevalence of hepatitis G virus (HGV) and hepatitis C virus (HCV) infections in deceased injection drug users and for comparison of the detection rates of HGV and HCV RNA in liver tissue with detection rates in postmortem serum samples, RT-PCR was performed in 50 drug abuse-related fatalities. HGV RNA w...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140050195
更新日期：1998-01-01 00:00:00
abstract：:Fatal head trauma (FHT) represents one of the most frequent causes of death diagnosed in forensic pathology. However, profound statistic autopsy data on FHT is still sparse. Therefore, the purpose of this study was to investigate the circumstances and injury patterns of FHT with particular focus on age and sex, and ad...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-019-02187-x
更新日期：2020-01-01 00:00:00
abstract：:We analysed 15 autosomal STRs in 200 unrelated individuals (102 males and 98 females) and 17 Y-STRs in 102 unrelated males living in Jharkhand, India, to establish parameters of forensic interest. The examined autosomal STRs revealed high combined power of exclusion (CPE) and combined power of discrimination (CPD) as ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-017-1610-x
更新日期：2018-01-01 00:00:00
abstract：:In humans, the amelogenin gene is present on both the X and the Y chromosomes. However, there are size differences in this gene between these chromosomes, which have been utilised for sexing in forensic casework and prenatal diagnosis. Our study using the AmpFl STR Profiler Plus kit, showed a deletion of Y chromosome-...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-001-0262-y
更新日期：2002-04-01 00:00:00
abstract：:In the present study 161 Japanese father/son haplotype transfers in 147 pedigrees were analyzed at 14 Y-STRs with two multiplex PCR-based typing systems. Five isolated single repeat mutations were identified at the DYS389I, DYS439, Y-GATA-H4, DYS389II and DYS391 loci, and a pedigree showing triple alleles at the DYS38...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-003-0422-3
更新日期：2004-06-01 00:00:00
abstract：:We have studied the correlation between the level of D-aspartic acid in dentin and the period of dentin formation in different types of teeth from the same individual. Except for the third molar, it is generally agreed that the formation of permanent dentin follows the pattern of growth, occurring earliest in the firs...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-003-0365-8
更新日期：2003-06-01 00:00:00
abstract：:The localization of ABH related antigens in human male reproductive tract was examined using monoclonal antibodies and an avidin biotin complex method. No positive reaction with blood group antibodies on spermatozoa was observed in testis and ductus epididymidis apart from erythrocytes and endothelial cells. The expre...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/BF02340827
更新日期：1992-01-01 00:00:00
abstract：:Scars of human skin can on occasions provide a very useful ancillary method of identification of an unknown deceased. If the age of any visible scars can be estimated objectively, then this might be of some assistance in the identification procedure. Melanocytes migrate into scar tissue as it ages and their number wit...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140100225
更新日期：2001-10-01 00:00:00
abstract：:Uniparental disomy (UPD) has attracted more attention recently in paternity testing, though it is an infrequent genetic event. Although short tandem repeat (STR) profiling has been widely used in paternity testing, it is not sufficient to use STR only to judge the genetic relationship, because the existence of UPD wil...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-019-02215-w
更新日期：2020-05-01 00:00:00
abstract：:The present paper analyses the applicability of the clinically prevalent skeletal age determination method of Tanner and Whitehouse for forensic age estimation in living individuals. For this purpose, the hand X-rays from 48 boys and 44 girls aged 12-16 years were evaluated retrospectively. The minima and maxima, the ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-008-0237-3
更新日期：2008-07-01 00:00:00
abstract：:The case concerns the sudden death of a 21-year-old male during a soccer game. The autopsy revealed large, calcified saccular aneurysms at the origins of both the left anterior descending and the right coronary arteries. Histologically, the wall of the aneurysms was thin and composed of an internal fibro-calcified lay...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140050213
更新日期：1999-01-01 00:00:00
abstract：:Suppose that part of the prosecution's evidence in some crime case is analysis of a blood stain, and that the traits E discovered in the stain suggest multiple donors. Then the prosecution will probably allege some specific inculpatory hypothesis H0 about the sources of the stain, and P (E [symbol: see text] H0) can b...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/BF01225523
更新日期：1996-01-01 00:00:00
abstract：:A total of 17 Y-specific STR loci were studied in 12 districts of the European part of Russia aiming to ascertain the amount of substructure required for the construction of a representative regional database. All groups exhibited high haplotype diversities but low inter-population variance as measured by an analysis ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-007-0222-2
更新日期：2008-05-01 00:00:00
abstract：:We present a single case report illustrating the diagnostic role of multi-slice computed tomography (MSCT) in the investigation of suspicious child death where mechanical asphyxia is suspected. The case illustrates how radiological findings that may not be observable on conventional plain X-ray were identified by post...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-010-0438-4
更新日期：2010-11-01 00:00:00
abstract：:We measured the quantity of D-aspartic acid (degree of racemization of aspartic acid) in the enamel of different types of teeth from the same individual. We studied the correlation between the degree of racemization and the time of formation of each particular tooth, as well as the applicability of the degree of racem...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-004-0506-8
更新日期：2005-03-01 00:00:00
abstract：:Paradoxical undressing is a phenomenon characterizing some fatal hypothermia cases. The victims, despite low environmental temperatures, paradoxically remove their clothes due to a sudden feeling of warmth. In this report, we describe a case of suspected paradoxical undressing in a non-hypothermia case. The victim, a ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-017-1597-3
更新日期：2017-09-01 00:00:00
abstract：:The purpose of this study was to explore the applicability of periodontal ligament visibility (PLV) at the 18-year threshold. This mandibular maturity marker is graded into four separate age related stages, PLV-A, PLV-B, PLV-C, and PLV-D. These are discernible on a dental panoramic tomograph (DPT). The sample comprise...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-016-1468-3
更新日期：2017-05-01 00:00:00
abstract：:Methadone plays an increasing role in drug-related deaths in Hamburg. To find out whether intravenous application of methadone plays a relevant role in methadone-related deaths, body fluids of all methadone-positive cases (n=130) and three buprenorphine-positive cases where a urine sample was available (n=58+3) were i...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-014-1017-x
更新日期：2014-09-01 00:00:00
abstract：:Allele frequencies and forensic parameters for 17 autosomal short tandem repeat (STR) loci were investigated from 1542 individuals of Va ethnic minority in Yunnan Province in the southwest of China. Also, genetic distances between Va and 13 published populations were compared, and a neighbor-joining (NJ) phylogenetic ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-017-1620-8
更新日期：2017-09-01 00:00:00
abstract：:One of the most common conditions during fetal development is anencephaly, which often involves many identification difficulties in the context of physical anthropology, as it causes severe skull challenges. In this paper, we describe the alterations found in the skulls of two perinatal individuals with anencephaly fr...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-014-1123-9
更新日期：2015-07-01 00:00:00
abstract：:The Ion AmpliSeq™ HID single nucleotide polymorphism (SNP) panel, a primer pool of 103 autosomal SNPs and 33 Y-SNPs, was evaluated using the Ion 314™ Chip on the Ion PGM™ Sequencer with four DNA samples. The study focused on the sequencing of DNA at three different initial target quantities, related interpretation iss...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-013-0879-7
更新日期：2013-11-01 00:00:00
abstract：:Contrary to the traditional dogma of being a relatively invariable and quiescent organ lacking the capability to regenerate, there is now widespread evidence that the human brain harbors multipotent neural stem cells, possibly throughout senescence. These cells can divide and give rise to neuroectodermal progeny in vi...
journal_title：International journal of legal medicine
pub_type： 杂志文章,评审
doi：10.1007/s00414-005-0037-y
更新日期：2006-07-01 00:00:00
abstract：:The genetic polymorphisms of 21 autosomal short tandem repeat (STR) loci included in the GlobalFiler™ PCR Amplification Kit were evaluated in 3032 unrelated individuals Altay Han of Xinjiang, northwest China. All of the loci reached the Hardy-Weinberg equilibrium. These loci were examined to determine allele frequenci...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-017-1641-3
更新日期：2018-01-01 00:00:00
abstract：:Inferring an unknown DNA's ancestry using a set of ancestry-informative single nucleotide polymorphisms (SNPs) in forensic science is useful to provide investigative leads. This is especially true when there is no DNA database match or specified suspect. Thus, a set of SNPs with highly robust and balanced differential...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-018-1863-z
更新日期：2019-07-01 00:00:00
abstract：:The use of DNA to determine the ancestry of an individual is becoming more and more important in the areas of forensics. Kidd et al. (Forensic Sci Int Genet 12:215-224, 2014) have been the first to identify and catalog haplotypes, termed as minihaplotypes (1-10-kilobase spans) and microhaplotypes (≤ 200 bp), with pote...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-018-1881-x
更新日期：2019-07-01 00:00:00
abstract：:The formation of skull fractures is an important topic in legal medicine. In particular, the influence of boundary conditions is controversially discussed in the literature. A study focusing solely on this aspect was missing. This study aimed to investigate the influence of boundary conditions on the energy threshold ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-019-02023-2
更新日期：2020-03-01 00:00:00
abstract：:The alcoholism marker CDT was determined on 257 blood samples 1-2 days after the blood samples were taken and again after storage for 7 months at +4 degrees C. The differences between the pairs of CDT values were so large that the determination of CDT after long term storage of the blood sample has no evidential value...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140050013
更新日期：2000-01-01 00:00:00
abstract：:The unique case of a 50-year-old known alcoholic whose corpse was exhumed 27 years after death is reported. The man apparently committed suicide by hanging, but many years later the case was questioned and homicide-linked to a long-lasting serial killer case-was suspected. Thus, the corpse was exhumed, and at the auto...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-008-0273-z
更新日期：2008-11-01 00:00:00
