Abstract：
:DNA typing was carried out on epithelial cells which were transferred from the hands of the suspect onto the neck of the victim. In an experimental study 16 suspect-victim combinations were investigated for estimating the typing success. Alternatively to an attack against the neck, the upper arm was used for "strangulation". PCR typing was carried out using the short tandem repeat systems (STRs) HumCD4, HumVWF31A (VWA) and Hum-FIBRA (FGA) and the success rate was > 70% for all 3 systems. In most of the cases mixed patterns containing the phenotype of the suspect and the victim were obtained. In a case where strangulation was the cause of death, epithelial cells could be removed from the neck of the victim. The DNA pattern of the suspect could be successfully amplified using four STRs, demonstrating the applicability of this approach for practical casework.
journal_name
Int J Legal Medjournal_title
International journal of legal medicineauthors
Wiegand P,Kleiber Mdoi
10.1007/s004140050063subject
Has Abstractpub_date
1997-01-01 00:00:00pages
181-3issue
4eissn
0937-9827issn
1437-1596journal_volume
110pub_type
杂志文章abstract：:P-glycoprotein (P-gp), encoded by the ABCB1/MDR1 gene, is a drug transporter at the blood-brain barrier. Several polymorphisms in the ABCB1 gene are known to affect the activity and/or expression of P-gp, thereby influencing the treatment response and toxicity of P-gp substrates like citalopram and venlafaxine. In thi...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-013-0849-0
更新日期：2013-05-01 00:00:00
abstract：:Brazilian population derives from Native Amerindians, Europeans, and Africans. Southeastern Brazil is the most populous region of the country. The present study intended to characterize the maternal genetic ancestry of 290 individuals from southeastern (Brazil) population. Thus, we made the sequencing of the three hyp...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-014-1023-z
更新日期：2014-07-01 00:00:00
abstract：:According to European regulations and the legislations of individual member states, children who seek asylum have a different set of rights than adults in a similar position. To protect these rights and ensure rule of law, migration authorities are commonly required to assess the age of asylum seekers who lack reliabl...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-017-1730-3
更新日期：2018-05-01 00:00:00
abstract：:We report about the case of a sudden unexpected death of a 25-year-old male suffering from infectious disease. An autopsy was ordered with no final premortem diagnosis. Microscopic and microbiological examination revealed a pneumococcal bronchopneumonia and hemophagocytic lesions in the bone marrow. After integrating ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-015-1305-0
更新日期：2016-05-01 00:00:00
abstract：:The measurement of the myeloperoxidase activity was used to quantify the acute granulocyte reaction. A 35% loss of blood resulted in a clear decrease of the myeloperoxidase activity at the edges of experimental incision wounds in rat skin in the first day after inflicting the wounds. After 12 h only about one-third an...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140050101
更新日期：1998-01-01 00:00:00
abstract：:Mitragyna speciosa (Rubiaceae), commonly known as kratom, is a tropical tree with a long history of traditional use in parts of Africa and Southeast Asia. In recent years, kratom has gained popularity for use as a recreational drug across the globe. Relatively new to the illicit market and used in a manner different f...
journal_title：International journal of legal medicine
pub_type： 杂志文章,评审
doi：10.1007/s00414-015-1279-y
更新日期：2016-01-01 00:00:00
abstract：:The goal of the present study is to examine cross-sectional information on the growth of the humerus based on the analysis of four measurements, namely, diaphyseal length, transversal diameter of the proximal (metaphyseal) end of the shaft, epicondylar breadth and vertical diameter of the head. This analysis was perfo...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-012-0713-7
更新日期：2013-01-01 00:00:00
abstract：:Haemorrhages at the periostal-clavicular origin of the sternocleidomastoid muscles were found in 52 out of 54 cases of death by hanging. This cervical haemorrhage is most frequently found in death by hanging, but only seldomly seen in other causes of death and can therefore be regarded as being typical for death by ha...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/BF01844825
更新日期：1995-01-01 00:00:00
abstract：:In this study, we assessed 30 insertion-deletion polymorphisms (Indels) (Investigator DIPplex® kit) in four Chinese populations (n = 952) and evaluated their usefulness in forensic genetic applications. After the Bonferroni correction at a 95 % significance level (p = 0.0017), there were no deviations from the Hardy-W...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-014-1091-0
更新日期：2015-01-01 00:00:00
abstract：:The case of a man's death as a consequence of an accident with a mountain bike was examined. Despite only slight external injuries, a general examination revealed the existence of a rupture of the diaphragm which was the ultimate cause of death. The discussion reconstructs the way the accident occurred and briefly ana...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140100237
更新日期：2001-12-01 00:00:00
abstract：:The name of an author was misspelled. The correct spelling is "Linlin Gao" instead of Linin Gao. ...
journal_title：International journal of legal medicine
pub_type： 已发布勘误
doi：10.1007/s00414-020-02342-9
更新日期：2020-11-01 00:00:00
abstract：:Abstract DNA typing of four tetrameric repeat loci (HUMVWA, HUMTH0I, D21SII and HPRT) was carried out in a Chinese Han population from Shanghai (East China) and one from Guangzhou (South-East China) using a quadruplex PCR amplification and detection of the fluorescent-labeled alleles on the ALF DNA sequencer. All loci...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140050187
更新日期：1998-01-01 00:00:00
abstract：:Establishing individuality is an imperative aspect in any investigation procedure. At times, it becomes necessary to determine the sex of the individual to establish identity, and saliva stains found at the scene of crime are of major help in such cases. In the present study, we have determined the sex of the individu...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-008-0285-8
更新日期：2009-09-01 00:00:00
abstract：:The purpose of this study is to evaluate allelic association and linkage of 18 adjacent syntenic short tandem repeat (STR) pairs form out of 30 markers located on 12 different autosomes. Linkage disequilibrium was tested by using the unknown gametic phase genotypes and phased haplotypes from 290 unrelated individuals ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-014-1032-y
更新日期：2014-09-01 00:00:00
abstract：:Plant exposures are among the most frequently reported cases to poison control centres worldwide. This is a growing condition due to recent societal trends oriented towards the consumption of wild plants as food, cosmetics, or medicine. At least three general causes of plant poisoning can be identified: plant misident...
journal_title：International journal of legal medicine
pub_type： 杂志文章,评审
doi：10.1007/s00414-016-1460-y
更新日期：2017-01-01 00:00:00
abstract：:The aim of this study was to measure catecholamines and their O-methylated metabolites in urine and vitreous humor collected in cardiac deaths and noncardiac control cases that underwent medicolegal investigations. Our first goal was to assess whether cardiac events of different types are characterized by different ca...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-015-1303-2
更新日期：2016-07-01 00:00:00
abstract：:Linking biological samples found at a crime scene with the actual crime event represents the most important aspect of forensic investigation, together with the identification of the sample donor. While DNA profiling is well established for donor identification, no reliable methods exist for timing forensic samples. He...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-010-0457-1
更新日期：2010-09-01 00:00:00
abstract：:Determining the time of injury is an important but still a challenging task in forensic anthropology. In literature, many descriptions can be found to make a distinction between perimortem and postmortem fractures. Characteristics that are more related to fractures in fresh conditions, however, are not extensively inv...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-016-1514-1
更新日期：2017-05-01 00:00:00
abstract：:We present a case of fatal intoxication by the application of a transdermal fentanyl patch upon a superficial bleeding abrasion of a 2-year-old girl. The grandmother discovered the body of the child in bed at approximately 7 a.m. External examination revealed a properly developed, nourished, and hydrated child, with s...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-015-1209-z
更新日期：2015-11-01 00:00:00
abstract：:Gabapentin (GBP) (Neurontin®, Horizant®, Gralise®) is a widely prescribed medication used primarily for the treatment of epilepsy and neuropathic pain. GBP has a favorable adverse effect profile in therapeutic dosing with the most common reported effects being dizziness, fatigue, drowsiness, weight gain, and periphera...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-015-1193-3
更新日期：2015-07-01 00:00:00
abstract：:The assistance provided by specialised healthcare personnel to victims of a sexual violence cannot focus just on the clinical intervention appropriate for the lesions suffered by the patient, but must also take legal and forensic needs into account. Anamnestic data represents a crucial step towards the finding of fore...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-017-1602-x
更新日期：2017-09-01 00:00:00
abstract：:Expert witness opinion based on the comparison of images has been accepted by UK courts as admissible evidence in relation to issues of identity. Within images of the hand are a multiplicity of anatomical features of different aetiology, incidence and distribution patterns and this includes melanocytic nevi, referred ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-013-0821-z
更新日期：2014-05-01 00:00:00
abstract：:In the immigration case cited by Jeffreys et al. (1985), the biostatistical evaluation of blood group findings in 16 systems and of HLA-A,B findings for the mother and child, using a special kinship algorithm developed by Ihm and Hummel (1975), produced a probability of maternity of the Ghanaian-born putative mother o...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/BF01371238
更新日期：1992-01-01 00:00:00
abstract：:Evaluation of the radiographic visibility of root pulp in mandibular third molars has been suggested as an alternative method for estimation of legal age threshold in living individuals when the root apices are mature. Here, we assessed the accuracy of this method for age thresholds of 18 and 21 years. A sample of 463...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-019-02036-x
更新日期：2019-09-01 00:00:00
abstract：:Anthropologists are constantly seeking to improve methods for age estimation in the human skeleton. A new method was introduced about a decade ago that assesses the morphological changes that take place in the acetabulum as an individual ages. The pelvis is usually well preserved in forensic cases, which makes this me...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-015-1299-7
更新日期：2016-05-01 00:00:00
abstract：:When blood reaches an extracorporeal surface, a drying process is initiated. Properties of this drying process may be crucial for the correct assessment of case-specific time lapses, however, there is a lack of systematic studies concerning the drying times of blood. We present a study on drying properties of small bl...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-012-0734-2
更新日期：2012-09-01 00:00:00
abstract：:Short tandem repeats (STRs) are DNA regions with a variable number of repeated units (2-6 bp) and attractive to genetic application like forensic, population genetics, and anthropological studies. The Huaxia Platinum System allows the multiplex amplification of 23 autosomal STR loci and two gender determination loci. ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-017-1679-2
更新日期：2018-07-01 00:00:00
abstract：AIM:The aim of the current study was to retrospectively collect dental panoramic radiographs from Somali children living in Finland, to use the radiographic data to develop a new age estimation model based on the model established by Willems et al. (J Forensic Sci 46(4):893-895, 2001), and to compare the age prediction...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-018-1926-1
更新日期：2018-11-01 00:00:00
abstract：:Human fingertip microflora is transferred to touched objects and may provide forensically relevant information on individual hosts, such as on geographic origins, if endogenous microbial skin species/strains would be retrievable from physical fingerprints and would carry geographically restricted DNA diversity. We tes...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-009-0352-9
更新日期：2010-09-01 00:00:00
abstract：:The genetic polymorphisms of 21 autosomal short tandem repeat (STR) loci included in the GlobalFiler™ PCR Amplification Kit were evaluated in 3032 unrelated individuals Altay Han of Xinjiang, northwest China. All of the loci reached the Hardy-Weinberg equilibrium. These loci were examined to determine allele frequenci...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-017-1641-3
更新日期：2018-01-01 00:00:00
