Abstract：
:We present the case of a 3.5-year-old boy with sudden anal blood loss at school. Sexual abuse was suspected, and, apart from anal fissures seen on sigmoidoscopy, no other clinical signs of any sort of disorder were present. As no medical explanation for the blood loss could be given, penetrating anal trauma was suggested. During follow-up consultations, there were complaints of occasional blood loss. Platelet aggregation tests and electron microscopy finally helped diagnose a delta-storage pool disease which is a rare haemostatic disorder involving the dense granules of the platelets. Although exclusion of well-known blood diseases through routine laboratory testing is a common practice in children with sudden blood loss, this case illustrates the value of more specialised investigation both from a diagnostic and forensic point of view.
journal_name
Int J Legal Medjournal_title
International journal of legal medicineauthors
De Munnynck K,Van Geet C,De Vos R,Van de Voorde Wdoi
10.1007/s00414-005-0053-ysubject
Has Abstractpub_date
2007-01-01 00:00:00pages
44-7issue
1eissn
0937-9827issn
1437-1596journal_volume
121pub_type
杂志文章,评审abstract：:We have studied the correlation between the level of D-aspartic acid in dentin and the period of dentin formation in different types of teeth from the same individual. Except for the third molar, it is generally agreed that the formation of permanent dentin follows the pattern of growth, occurring earliest in the firs...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-003-0365-8
更新日期：2003-06-01 00:00:00
abstract：:One of the most fundamental issues in forensic anthropology is the determination of sex and population affinity based on various skeletal elements. Therefore, we compared the sexual dimorphism of the upper facial skeleton from a recent Czech population (twenty-first century) with that of a population from Early Modern...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-017-1625-3
更新日期：2018-01-01 00:00:00
abstract：:Population genetic studies were carried out on randomly selected and unrelated healthy individuals from Sicily (n = 140-150 individuals) using the short tandem repeat (STR) systems HumTH01, HumvWA31, HumFESFPS and HumF13A01. After vertical electrophoresis on polyacrylamide denaturing gels 6 alleles could be identified...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140050171
更新日期：1998-01-01 00:00:00
abstract：:To examine the prevalence of hepatitis G virus (HGV) and hepatitis C virus (HCV) infections in deceased injection drug users and for comparison of the detection rates of HGV and HCV RNA in liver tissue with detection rates in postmortem serum samples, RT-PCR was performed in 50 drug abuse-related fatalities. HGV RNA w...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140050195
更新日期：1998-01-01 00:00:00
abstract：:A 41-year-old healthy Caucasian male showed an unidentifiable direct AB0 group and a B group by an indirect method revealing the presence of natural antibodies anti-A1 and anti-A2. Mixed fields with anti-B and anti-A+B antisera led to the conclusion that blood group B and 0 cell populations were present in a 1:1 ratio...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-009-0332-0
更新日期：2009-09-01 00:00:00
abstract：:The Ion AmpliSeq™ HID single nucleotide polymorphism (SNP) panel, a primer pool of 103 autosomal SNPs and 33 Y-SNPs, was evaluated using the Ion 314™ Chip on the Ion PGM™ Sequencer with four DNA samples. The study focused on the sequencing of DNA at three different initial target quantities, related interpretation iss...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-013-0879-7
更新日期：2013-11-01 00:00:00
abstract：:A study was performed on the detection, separation and quantification of isomers from the new designer drugs named fluoroamphetamines (FAs) in forensic cases in eastern Denmark. The drugs were detected in whole blood extracts by ultraperformance liquid chromatography with time of flight mass spectrometer (UPLC-TOF-MS)...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-012-0671-0
更新日期：2012-07-01 00:00:00
abstract：:Immunohistochemical investigation of the respiratory tract and lungs of 63 fire victims revealed a statistically significant enhanced expression of heat-shock protein 70 (Hsp70) in the epiglottis, the trachea, and the main and the peripheral bronchi compared with a control group. In the fire victims, a strong expressi...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-006-0105-y
更新日期：2006-11-01 00:00:00
abstract：:Contrary to the traditional dogma of being a relatively invariable and quiescent organ lacking the capability to regenerate, there is now widespread evidence that the human brain harbors multipotent neural stem cells, possibly throughout senescence. These cells can divide and give rise to neuroectodermal progeny in vi...
journal_title：International journal of legal medicine
pub_type： 杂志文章,评审
doi：10.1007/s00414-005-0037-y
更新日期：2006-07-01 00:00:00
abstract：:The development rate of immature Calliphora vicina reared on decomposed liver was significantly slower, by as much as 30 h (55.4 % of total development time) for mid-sized larvae, and 71 h (35.0 %) and 58 h (14.6 %) if using times to the onset of pupariation and eclosion, respectively, than those of immatures that dev...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-012-0697-3
更新日期：2013-01-01 00:00:00
abstract：:The identification of species of the forensically important genus Sarcophaga is very difficult and requires strong taxonomic expertise. In this study, we sequenced the mitochondrial cytochrome c oxidase subunit I (COI) gene of 126 specimens of 56 W European Sarcophaga species and added GenBank data to our database to ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-012-0767-6
更新日期：2013-03-01 00:00:00
abstract：PURPOSE:We investigated the incidence and distribution of post-mortem gas detected with multidetector computed tomography (MDCT) to identify factors that could distinguish artifactual gas from cardiac air embolism. MATERIAL AND METHODS:MDCT data of 119 cadavers were retrospectively examined. Gas was semiquantitatively...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-010-0542-5
更新日期：2012-01-01 00:00:00
abstract：:In Japan and elsewhere, ABO genotyping is frequently used in forensic practice for identification of a decomposed body. However, the phenotype deduced from the genotyping data is occasionally inconsistent with the real phenotype. In this paper, we report a simple ABO genotyping method in which five single nucleotide p...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-006-0148-0
更新日期：2008-01-01 00:00:00
abstract：:The population origin of an individual is often requested to be determined from specimens left at a crime scene for identifying a suspect and individual identity. The melanocortin 1 receptor gene (MC1R) and P gene are associated with human pigmentation. Although several studies have reported that these genes are highl...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-008-0289-4
更新日期：2009-05-01 00:00:00
abstract：:The utility of postmortem microbiology has continuously been a topic of controversy. The present study describes a case of fatal sepsis in a patient with systemic lupus erythematosus. Postmortem culture and genotyping analyses allowed us to identify Klebsiella pneumoniae as the cause of sepsis, revealing the inadequat...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-015-1160-z
更新日期：2015-09-01 00:00:00
abstract：:The diagnosis of drowning is one of the most difficult in forensic medicine. Forensic diatomology has been proposed to be useful in solving the diagnosis of drowning and considered to be a reliable indicator of the site of drowning. The Yangtze River and Jialing River are the main rivers in the Chongqing area (China),...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-020-02297-x
更新日期：2020-07-01 00:00:00
abstract：:In a Japanese population study of the D1S80 locus 24 alleles ranging from allele 16 to allele43 were analysed using PCR-RFLP. As two repeat units were found to contain the restriction cleavage site (CCAGG) for EcoRII, we digested the alleles with EcoRII, separated the digested fragments on polyacrylamide gels and stai...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140050146
更新日期：1998-01-01 00:00:00
abstract：:Myocardial pathology and cardiac functional abnormalities known to occur in association with chronic alcohol abuse have been attributed to a direct toxic effect of ethanol on the intra-myocardial vasculature: alcohol-induced occlusion of small arteries with consequent secondary ischaemia leads to individual myocyte lo...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/BF01225513
更新日期：1996-01-01 00:00:00
abstract：:Shotguns are usually used to fire multiple pellets, but they are capable of firing single projectiles. Shotgun slug injuries are rare, severe, and fully comparable to those inflicted by high-velocity projectiles. A case of gunshot suicide of a 59-year-old man with a shotgun loaded with shotgun slugs is presented. The ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-009-0325-z
更新日期：2010-01-01 00:00:00
abstract：:The likelihood ratio is the fundamental quantity that summarizes the evidence in forensic cases. Therefore, it is important to understand the theoretical properties of this statistic. This paper is the last in a series of three, and the first to study linked markers. We show that for all non-inbred pairwise kinship co...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-016-1416-2
更新日期：2016-11-01 00:00:00
abstract：:Sequence variation of the hypervariable segments (HVS) I/II of mitochondrial DNA (mtDNA) and the haplogroup affiliation were determined in a sample of 271 Italian subjects. This analysis showed that 42% of the individuals could be ascribed to H, the most frequent haplogroup in European Caucasian populations. This frac...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-005-0059-5
更新日期：2006-05-01 00:00:00
abstract：:A population study in a sample of 211 unrelated individuals from 2 cities in North and Central Italy was carried out to investigate the short tandem repeat (STR) system HUMVWA31. Separation of PCR- amplified DNA fragments was performed by high-resolution horizontal denaturing polyacrylamide gel electrophoresis (PAGE) ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/BF01428399
更新日期：1995-01-01 00:00:00
abstract：:To investigate the genetic variation and forensic efficiency of 19 X-STR loci in the Zhuang and Mulao minorities, we calculated allele frequencies, forensic parameters, and haplotype frequencies of 405 Zhuang and 234 Mulao unrelated healthy individuals from Guangxi Zhuang Autonomous Region of China. Furthermore, we an...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-019-02004-5
更新日期：2020-03-01 00:00:00
abstract：:A case report of a 25-year-old man who committed suicide by intravenous injection himself of an aqueous home-made castor bean extract is presented. The patient was hospitalized and treated symptomatically and was released at its own request fourth day after intoxication. The next day, the patient's condition deteriora...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-020-02340-x
更新日期：2020-11-01 00:00:00
abstract：:Current analysis of forensic DNA stains relies on the probabilistic interpretation of bulk-processed samples that represent mixed profiles consisting of an unknown number of potentially partial representations of each contributor. Single-cell methods, in contrast, offer a solution to the forensic DNA mixture problem b...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-021-02503-4
更新日期：2021-01-23 00:00:00
abstract：:Little is known about what bereaved parents feel about the autopsy performed on their child. A multi-centre case control study of sudden infant death syndrome (SIDS) victims was carried out in Germany between 1998 and 2001, in which all infants had been autopsied. We performed a follow-up study 4-7 years after the par...
journal_title：International journal of legal medicine
pub_type： 杂志文章,多中心研究
doi：10.1007/s00414-006-0100-3
更新日期：2006-11-01 00:00:00
abstract：:The accuracy of most age determination methods in adults is unsatisfactory and therefore more precise methods are required. Teeth provide several useful points about an individuals age. With advancing age secondary dentine is deposited along the wall of the dental pulp chamber leading to a reduction in the size of the...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-004-0492-x
更新日期：2005-01-01 00:00:00
abstract：:Mixture DNA profiles commonly appear in forensic genetics, and a large number of statistical methods and software are available for such cases. However, most of the literature concerns mixtures where the contributors are assumed unrelated and the genetic markers are unlinked. In this paper, we consider mixtures of lin...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-015-1288-x
更新日期：2016-05-01 00:00:00
abstract：:Immunohistochemistry is a well-established technique used in many research laboratories as well as in clinical diagnostics. The method allows to visualize the expression of proteins in biological tissues, as well as to evaluate this expression semi-quantitatively. For diagnosis, an optimal staining, based on a straigh...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-017-1575-9
更新日期：2017-11-01 00:00:00
abstract：:Lactate dehydrogenase isoenzyme patterns indicative of vaginal injury were identified in extracts of a bloodstain on a pair of knickers belonging to a 4-year-old girl. No evidence of semen or saliva was detected in the stain. The result corroborated the clinical findings and provided strong evidence of child sexual ab...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/BF01625173
更新日期：1992-01-01 00:00:00
