Neural-network-based Motion Tracking for Breast Ultrasound Strain Elastography: An Initial Assessment of Performance and Feasibility.

Abstract:

:Accurate tracking of tissue motion is critically important for several ultrasound elastography methods. In this study, we investigate the feasibility of using three published convolution neural network (CNN) models built for optical flow (hereafter referred to as CNN-based tracking) by the computer vision community for breast ultrasound strain elastography. Elastographic datasets produced by finite element and ultrasound simulations were used to retrain three published CNN models: FlowNet-CSS, PWC-Net, and LiteFlowNet. After retraining, the three improved CNN models were evaluated using computer-simulated and tissue-mimicking phantoms, and in vivo breast ultrasound data. CNN-based tracking results were compared with two published two-dimensional (2D) speckle tracking methods: coupled tracking and GLobal Ultrasound Elastography (GLUE) methods. Our preliminary data showed that, based on the Wilcoxon rank-sum tests, the improvements due to retraining were statistically significant (p < 0.05) for all three CNN models. We also found that the PWC-Net model was the best neural network model for data investigated, and its overall performance was on par with the coupled tracking method. CNR values estimated from in vivo axial and lateral strain elastograms showed that the GLUE algorithm outperformed both the retrained PWC-Net model and the coupled tracking method, though the GLUE algorithm exhibited some biases. The PWC-Net model was also able to achieve approximately 45 frames/second for 2D speckle tracking data investigated.

journal_name

Ultrason Imaging

journal_title

Ultrasonic imaging

authors

Peng B,Xian Y,Zhang Q,Jiang J

doi

10.1177/0161734620902527

subject

Has Abstract

pub_date

2020-03-01 00:00:00

pages

74-91

issue

2

eissn

0161-7346

issn

1096-0910

journal_volume

42

pub_type

杂志文章
  • Adaptive imaging using an optimal receive aperture size.

    abstract::Sidelobe contribution from off-axis targets degrades image quality in a coherent array imaging system. In ultrasound imaging, focusing errors resulting from sound-velocity inhomogeneities in human tissue--also known as phase aberrations reduce the coherence of the received signals and elevate the sidelobe level. This ...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173460502700205

    authors: Li ML,Huang SW,Ustüner K,Li PC

    更新日期:2005-04-01 00:00:00

  • Optical tracking of superficial dynamics from an acoustic radiation force-induced excitation.

    abstract::Acoustic radiation force (ARF) has become a common excitation mechanism in elasticity imaging. The high acoustic intensities and subsequent generation of harmonics, however, hamper the effectiveness of using conventional radiofrequency (rf) tracking to investigate the dynamics of tissues and catheter-based transducers...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:

    authors: Bouchard RR,Van Soest G,Trahey GE,Van Der Steen AF

    更新日期:2009-01-01 00:00:00

  • Autoregressive spectral estimation in ultrasonic scatterer size imaging.

    abstract::An autoregressive (AR) spectral estimation method was considered for the purpose of estimating scatterer size images. The variance and bias of the resulting estimates were compared with those using classical FFT periodograms for a range of input signal-to-noise ratios and echo-signal durations corresponding to various...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173469601800102

    authors: Chaturvedi P,Insana MF

    更新日期:1996-01-01 00:00:00

  • Ultrasonographic Multimodality Diagnostic Model of Thyroid Nodules.

    abstract::The aim of this study was to identify independent risk factors for thyroid cancer, establish an ultrasonographic multimodality diagnostic model for thyroid nodules, and explore the diagnostic value of the model. From November 2011 to February 2015, 307 patients with a total of 367 thyroid nodules underwent conventiona...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/0161734618815070

    authors: Zhao RN,Zhang B,Jiang YX,Yang X,Lai XJ,Zhu SL,Zhang XY

    更新日期:2019-03-01 00:00:00

  • Wavelet-based speckle noise reduction in ultrasound B-scan images.

    abstract::Speckle noise is known to be signal-dependent in ultrasound imaging. Hence, separating noise from signal becomes a difficult task. This paper describes a wavelet-based method for reducing speckle noise. We derive from the model of the displayed ultrasound image the optimal wavelet-domain filter in the least mean-squar...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173460002200201

    authors: Rakotomamonjy A,Deforge P,Marché P

    更新日期:2000-04-01 00:00:00

  • Acoustic Structure Quantification Analysis of the Thyroid in Patients with Diffuse Autoimmune Thyroid Disease.

    abstract::The aim of this study was to assess whether acoustic structure quantification (ASQ) can differentiate normal from pathological thyroid parenchyma in patients with diffuse autoimmune thyroid disease (AITD). We evaluated 83 subjects (72 [87%] women and 11 [13%] men) aged 19 to 94 years with a mean age of 53 years. We pe...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/0161734615580766

    authors: Zandieh S,Bernt R,Zwerina J,Haller J,Knoll P,Seyeddain O,Mirzaei S

    更新日期:2016-03-01 00:00:00

  • Classification of scattering objects by regular arrays of scatterers using Fourier analysis.

    abstract::For a class of scattering objects the mean separation between the scatterers is determined. Over a range of frequencies, ultrasonic back-scattered pressure signals are recorded. It is suggested to derive the mean spacing of an unknown scattering object by employing Fourier analysis and comparing the signal with signal...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173468300500405

    authors: Koch I

    更新日期:1983-10-01 00:00:00

  • Digital simulation of pulsed ultrasonic waveforms.

    abstract::When modeling or simulating an ultrasonic pulse-echo system it is necessary to know the transducer waveforms that are the input to the system. In general, accurate transducer modeling is complex and waveform calculation is computationally intensive. Because of this, investigators often assume these waveforms to be sim...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173468700900405

    authors: Barber FE,Goodsitt MM

    更新日期:1987-10-01 00:00:00

  • Ultrasonic tomography of biological tissue.

    abstract::In this paper, quantitative tomographic reconstructions of biological tissue are presented. First, the experimental setup and a hybrid filtered backpropagation (FBP) technique are briefly described. Using this technique, which includes exact backpropagation of data prior to reconstruction by means of the classical FBP...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173469401600102

    authors: Sponheim N,Gelius LJ,Johansen I,Stamnes JJ

    更新日期:1994-01-01 00:00:00

  • Ultrasound velocity in fixed human liver: empirical anova and regression modelling on histologically assessed abnormalities.

    abstract::Anova and "dummy variables" least squares regression methods are used to investigate the dependence of ultrasound propagation velocity on the presence or absence of fat and on the rank ordered level of cirrhosis in fixed human liver. Cirrhosis is found to affect velocity in a nonlinear fashion, while fat depresses the...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173468300500306

    authors: Zimmermann KP,Smith JC

    更新日期:1983-07-01 00:00:00

  • Skeletal Muscle Fatigue State Evaluation with Ultrasound Image Entropy.

    abstract::Muscle fatigue often occurs over a long period of exercise, and it can increase the risk of muscle injury. Evaluating the state of muscle fatigue can avoid unnecessary overtraining and injury of the muscle. Ultrasound imaging can non-invasively visualize muscle tissue in real-time. Image entropy is commonly used to ch...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/0161734620952683

    authors: Li P,Yang X,Yin G,Guo J

    更新日期:2020-11-01 00:00:00

  • In vivo imaging using a copolymer phased array.

    abstract::Phased-array images have been obtained in vivo with a steered copolymer array operating at 2.5 MHz. The array was fabricated using 28 microns copolymer film, lambda/4 resonant at 21 MHz, which was bonded to a glass ceramic backing with a thin film bond. The 32 array elements were created by laser ablation of the conti...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173469201400302

    authors: Goldberg RL,Smith SW,Brown LF

    更新日期:1992-07-01 00:00:00

  • Effects of transmit focusing on finite amplitude distortion based second harmonic generation.

    abstract::Generation of the second harmonic signal was studied for finite amplitude distortion based harmonic imaging. Acoustic field amplitudes along the range axis of a fixed focus transducer were measured using a PVDF needle hydrophone. Results indicated that on-axis amplitudes strongly depended on the f-number at both the f...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173469902100401

    authors: Li PC,Shen CC

    更新日期:1999-10-01 00:00:00

  • Mathematical simulation of pressure pulse propagation in biological tissues.

    abstract::The propagation of pressure pulses of arbitrary time form in inhomogeneous attenuating media with characteristics similar to real biological tissues is considered. A mathematical model using the quasi-optical approximation is developed to solve the wave equation. Such a model proves to be convenient for computer reali...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173469301500106

    authors: Adrov VN,Chernomordik VV

    更新日期:1993-01-01 00:00:00

  • Compressed Sensing for Elastography in Portable Ultrasound.

    abstract::Portable ultrasound is recently emerging as a new medical imaging modality featuring high portability, easy connectivity, and real-time on-site diagnostic ability. However, it does not yet provide ultrasound elastography function that enables the diagnosis of malignant lesions using elastic properties. This is mainly ...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/0161734617716938

    authors: Shin B,Jeon S,Ryu J,Kwon HJ

    更新日期:2017-11-01 00:00:00

  • Adaptive texture feature extraction with application to ultrasonic image analysis.

    abstract::Computer texture analysis methods use texture features that are traditionally chosen from a large set of fixed features known in literature. These fixed features are often not specifically designed to the problem at hand, and as a result they may have low discriminative power, and/or may be correlated. Increasing the ...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章,评审

    doi:10.1177/016173469802000204

    authors: Huisman HJ,Thijssen JM

    更新日期:1998-04-01 00:00:00

  • Attenuation and backscatter estimation using video signal analysis applied to B-mode images.

    abstract::Most methods for in vivo quantitation of ultrasound attenuation and backscatter are not available clinically because they rely upon acquiring and analyzing radio frequency (rf) echo signals. This paper describes a technique to estimate ultrasound attenuation and backscatter from B-mode image data. The video signal ana...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173469701900305

    authors: Knipp BS,Zagzebski JA,Wilson TA,Dong F,Madsen EL

    更新日期:1997-07-01 00:00:00

  • Computerized quantification analysis of left ventricular wall motion from echocardiograms.

    abstract::Two-dimensional echocardiography (2-D echo) imaging is a more attractive clinical tool than other modalities that either involve radiation exposure or are too slow to image heart motion in real-time. Computer-aided analysis of left ventricular(LV) wall motion provides quantitative parameters for diagnosis. This study ...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173469701900204

    authors: Chen T,Chen TP,Tsai LM

    更新日期:1997-04-01 00:00:00

  • Feasibility exploration of blood flow estimation by contrast-assisted Nakagami imaging.

    abstract::The microbubble contrast agent destruction/replenishment technique has been widely applied to ultrasound-based blood flow estimation. The rate of increase of the time-intensity curve (TIC) due to microbubbles flowing into the region of interest as measured from B-mode images closely reflects the flow velocity. In this...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173460803000301

    authors: Tsui PH,Yeh CK,Chang CC

    更新日期:2008-07-01 00:00:00

  • Assessment of Age-related Oxygenation Changes in Calf Skeletal Muscle by Photoacoustic Imaging: A Potential Tool for Peripheral Arterial Disease.

    abstract::Peripheral artery disease is often asymptomatic, and various imaging and nonimaging techniques have been used for assessment and monitoring treatments. This study is designed to demonstrate the ability of photoacoustic imaging to noninvasively determine changes in tissue oxygenation that occur in mice's hind limb skel...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/0161734619862287

    authors: Kirkham BM,Schultz SM,Ashi K,Sehgal CM

    更新日期:2019-09-01 00:00:00

  • Phase-derivative imaging. I: Methods and stabilization analysis.

    abstract::The potential of using the phase derivative (PD) for echographic imaging was investigated. The PD data were calculated by four methods: zero crossing (ZCS) with squelch addition, analytic signal either with squelch addition (ASS) or with employment of a Wiener kernel (ASW), and unwrapped phase (UWP). The large peaks w...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173468700900301

    authors: Romijn RL,Oosterveld BJ,Thijssen JM

    更新日期:1987-07-01 00:00:00

  • Effective scatterer diameter estimates for broad scatterer size distributions.

    abstract::Acoustic form factors have been used to model the frequency dependence of acoustic scattering in phantoms and tissues. This work demonstrates that a broad range of scatterer sizes, individually well represented by Faran theory or a Gaussian form factor, is not accurately described by a single effective scatterer from ...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/0161734614534399

    authors: Nordberg EP,Hall TJ

    更新日期:2015-01-01 00:00:00

  • Reduction of the clutter component in Doppler ultrasound signals based on singular value decomposition: a simulation study.

    abstract::In pulsed Doppler ultrasound systems, the ultrasound radiofrequency (RF) signals received can be employed to estimate noninvasively the time-dependent blood velocity distribution within and artery. The RF signals are composed of signals originating from clutter (e.g., vessel walls) and scatterers (e.g., red blood cell...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173469701900101

    authors: Ledoux LA,Brands PJ,Hoeks AP

    更新日期:1997-01-01 00:00:00

  • Statistical relationship between ultrasound echo envelope and envelope peak.

    abstract::This study shows that the amplitude information of ultrasound echoes is carried mainly by the envelope peaks (EPs). It is first shown that the EPs in an A-line represent the maximum number of independent amplitude data. It is then demonstrated that the entire envelope could be approximately reconstructed from the EPs....

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173468801000403

    authors: He P

    更新日期:1988-10-01 00:00:00

  • Experimental Validation of ARFI Surveillance of Subcutaneous Hemorrhage (ASSH) Using Calibrated Infusions in a Tissue-Mimicking Model and Dogs.

    abstract::Acoustic radiation force impulse (ARFI) Surveillance of Subcutaneous Hemorrhage (ASSH) has been previously demonstrated to differentiate bleeding phenotype and responses to therapy in dogs and humans, but to date, the method has lacked experimental validation. This work explores experimental validation of ASSH in a po...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/0161734615617940

    authors: Geist RE,DuBois CH,Nichols TC,Caughey MC,Merricks EP,Raymer R,Gallippi CM

    更新日期:2016-09-01 00:00:00

  • Attenuation estimation with the zero-crossing technique: phantom studies.

    abstract::Global and local attenuation coefficient estimations were performed in a phantom using a pulse echo method based on the rate of decay of zero crossing density. Focussed and unfocussed 3.5 MHz transducers were used. It was found that good global estimates could be made with either transducer over a 2:1 range of attenua...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173468500700202

    authors: Ophir J,Ghouse MA,Ferrari LA

    更新日期:1985-04-01 00:00:00

  • Adaptive scan sequence for real-time ultrasound 3-D imaging.

    abstract::An adaptive scan sequence is proposed for real-time ultrasound three-dimensional (3-D) imaging. Generally, the refresh rate of 3-D imaging is limited by the view window, resolution and sound speed in the human body. If the object is transformed or moved during the data set acquisition, the 3-D image will be distorted....

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173460302500401

    authors: Hashimoto H,Takeuchi Y

    更新日期:2003-10-01 00:00:00

  • Quantitative assessment of in vivo backscatter enhancement from gelatin microspheres.

    abstract::Experimental work using a quantitative C-scan technique to measure in situ enhancement of hepatic backscatter resulting from the administration of gelatin microspheres to dogs is reported. We have found that reproducible enhancement of hepatic backscatter on the order of 2 dB followed the peripheral administration of ...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173468500700402

    authors: Ophir J,Gobuty A,Maklad N,Tyler T,Jaeger P,McWhirt R

    更新日期:1985-10-01 00:00:00

  • Linear arrays for vibro-acoustography: a numerical simulation study.

    abstract::In this work, we study linear array beamforming for vibro-acoustography systems. The goal of this research is to assess the feasibility of vibro-acoustography imaging systems based on linear arrays for clinical applications. The vibro-acoustography transducer is designed with two arrays driven by two continuous-wave o...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173460402600101

    authors: Silva GT,Greenleaf JF,Fatemi M

    更新日期:2004-01-01 00:00:00

  • The Maltese cross processor: speckle reduction for circular transducers.

    abstract::A new online signal processing technique is described to reduce speckle noise in ultrasound images. In the imaging system, a focused piston transducer is divided into thirty-two sectors. In the receive mode, parallel signal processing arranges the sectors into eight maltese crosses. The rf signals of the perpendicular...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173468801000301

    authors: Smith SW,von Ramm OT

    更新日期:1988-07-01 00:00:00