Abstract:
:The aim of this study was to identify independent risk factors for thyroid cancer, establish an ultrasonographic multimodality diagnostic model for thyroid nodules, and explore the diagnostic value of the model. From November 2011 to February 2015, 307 patients with a total of 367 thyroid nodules underwent conventional ultrasound, contrast-enhanced ultrasound (CEUS), and ultrasound elastography examinations before surgery. A binary logistic regression analysis was performed to identify independent risk factors for thyroid cancer and to establish a multimodality diagnostic model for thyroid nodules. The diagnostic performance of conventional ultrasound, CEUS, ultrasound elastography, and the multimodality diagnostic model was assessed and compared. The following seven independent risk factors were included in the logistic regression models: age, irregular shape, hypoechoic pattern, marked hypoechoic pattern, irregular blood flow distribution, heterogeneous enhancement, and an elastic score of 3/4. The multimodality diagnostic model had a diagnostic accuracy of 86.9%, with a sensitivity of 93.5% and a specificity of 77.3%. The multimodality diagnostic model improved the diagnostic accuracy compared with that of conventional ultrasound, CEUS, and ultrasound elastography. Independent risk factors for thyroid cancer included age, irregular shape, hypoechoic pattern, marked hypoechoic pattern, irregular blood flow distribution, heterogeneous enhancement, and an elastic score of 3/4. The multimodality diagnostic model was demonstrated to be effective in the diagnosis of thyroid nodules.
journal_name
Ultrason Imagingjournal_title
Ultrasonic imagingauthors
Zhao RN,Zhang B,Jiang YX,Yang X,Lai XJ,Zhu SL,Zhang XYdoi
10.1177/0161734618815070subject
Has Abstractpub_date
2019-03-01 00:00:00pages
63-77issue
2eissn
0161-7346issn
1096-0910journal_volume
41pub_type
杂志文章abstract::Tracking large deformations in tissue using ultrasound can enable the reconstruction of nonlinear elastic parameters, but poses a challenge to displacement estimation algorithms. Such large deformations have to be broken up into steps, each of which contributes an estimation error to the final accumulated displacement...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/0161734613479246
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journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173460602800103
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abstract::An adaptive scan sequence is proposed for real-time ultrasound three-dimensional (3-D) imaging. Generally, the refresh rate of 3-D imaging is limited by the view window, resolution and sound speed in the human body. If the object is transformed or moved during the data set acquisition, the 3-D image will be distorted....
journal_title:Ultrasonic imaging
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doi:10.1177/016173460302500401
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abstract::Two-dimensional echocardiography (2-D echo) imaging is a more attractive clinical tool than other modalities that either involve radiation exposure or are too slow to image heart motion in real-time. Computer-aided analysis of left ventricular(LV) wall motion provides quantitative parameters for diagnosis. This study ...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173469701900204
更新日期:1997-04-01 00:00:00
abstract::In recent years, adaptive minimum-variance (MV) beamforming has been successfully applied to medical ultrasound imaging, resulting in simultaneous improvement in imaging resolution and contrast. MV has high resolution and hence can provide accurate estimates of the target locations. However, the MV amplitude estimates...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/0161734615600167
更新日期:2016-07-01 00:00:00
abstract::Coherent speckle is a source of image noise in ultrasonic B-mode imaging. The use of multiple imaging frequencies has been suggested as a technique for speckle contrast reduction. This technique involves the averaging of images whose speckle patterns have been modified by a change in the spectrum of the transmitted or...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173468600800301
更新日期:1986-07-01 00:00:00
abstract::A new online signal processing technique is described to reduce speckle noise in ultrasound images. In the imaging system, a focused piston transducer is divided into thirty-two sectors. In the receive mode, parallel signal processing arranges the sectors into eight maltese crosses. The rf signals of the perpendicular...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173468801000301
更新日期:1988-07-01 00:00:00
abstract::Conventional ultrasonic B-mode images qualitatively describe tissue structures but are unsuitable for quantitative analyses of scatterer properties. We have recently developed an ultrasonic parametric imaging technique based on the Nakagami statistical distribution that is able to quantify scatterer concentrations. Th...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173460803000202
更新日期:2008-04-01 00:00:00
abstract::Regional anesthesia is preferred over general anesthesia for many surgical procedures; however, challenges associated with poor image guidance limit its widespread acceptance as a viable alternative. In B-mode ultrasound images, the current standard for guidance, nerves can be difficult to visualize due to their simil...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173460903100303
更新日期:2009-07-01 00:00:00
abstract::Breast ultrasound (BUS) imaging has become a crucial modality, especially for providing a complementary view when other modalities (i.e., mammography) are not conclusive in the task of assessing lesions. The specificity in cancer detection using BUS imaging is low. These false-positive findings often lead to an increa...
journal_title:Ultrasonic imaging
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doi:10.1177/0161734615589287
更新日期:2016-05-01 00:00:00
abstract::Ultrasonic waveform data from a tissue-mimicking phantom containing low contrast targets was digitized, stored and processed prior to creating and displaying ultrasonic images. Speckle reduction was performed by digital filtering of the waveform data with appropriately spaced and weighted digital filters, prior to bot...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173468700900202
更新日期:1987-04-01 00:00:00
abstract::In pulsed Doppler ultrasound systems, the ultrasound radiofrequency (RF) signals received can be employed to estimate noninvasively the time-dependent blood velocity distribution within and artery. The RF signals are composed of signals originating from clutter (e.g., vessel walls) and scatterers (e.g., red blood cell...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173469701900101
更新日期:1997-01-01 00:00:00
abstract::Previously reported data on the temperature dependence of propagation speed in tissues generally span only temperature ranges up to 60 degrees C. However, with the emerging use of thermal ablative therapies, information on variation in this parameter over higher temperature ranges is needed. Measurements of the ultras...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173460202400404
更新日期:2002-10-01 00:00:00
abstract::Mean frequency estimators as used in pulsed Doppler ultrasound equipment should provide an accurate (quality) and consistent (robustness) estimate over a wide range of signal conditions. In a simplified signal model, the main parameters to consider are the noise level, mean frequency, bandwidth and power of both the D...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173469201400404
更新日期:1992-10-01 00:00:00
abstract::Phased-array images have been obtained in vivo with a steered copolymer array operating at 2.5 MHz. The array was fabricated using 28 microns copolymer film, lambda/4 resonant at 21 MHz, which was bonded to a glass ceramic backing with a thin film bond. The 32 array elements were created by laser ablation of the conti...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173469201400302
更新日期:1992-07-01 00:00:00
abstract::Acoustic radiation force (ARF) has become a common excitation mechanism in elasticity imaging. The high acoustic intensities and subsequent generation of harmonics, however, hamper the effectiveness of using conventional radiofrequency (rf) tracking to investigate the dynamics of tissues and catheter-based transducers...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
abstract::Experimental work using a quantitative C-scan technique to measure in situ enhancement of hepatic backscatter resulting from the administration of gelatin microspheres to dogs is reported. We have found that reproducible enhancement of hepatic backscatter on the order of 2 dB followed the peripheral administration of ...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173468500700402
更新日期:1985-10-01 00:00:00
abstract::For a class of scattering objects the mean separation between the scatterers is determined. Over a range of frequencies, ultrasonic back-scattered pressure signals are recorded. It is suggested to derive the mean spacing of an unknown scattering object by employing Fourier analysis and comparing the signal with signal...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173468300500405
更新日期:1983-10-01 00:00:00
abstract::It is well-documented in literature that benign breast lesions, such as fibroadenomas, are loosely bonded to their surrounding tissue and tend to slip under a small quasi-static compression, whereas malignant lesions being firmly bonded to their surrounding tissue do not slip. Recent developments in quasi-static ultra...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/0161734616686746
更新日期:2017-05-01 00:00:00
abstract::An algorithm for deconvolution of medical ultrasound images is presented. The procedure involves estimation of the basic one-dimensional ultrasound pulse, determining the ratio of the covariance of the noise to the covariance of the reflection signal, and finally deconvolution of the rf signal from the transducer. Usi...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173469301500204
更新日期:1993-04-01 00:00:00
abstract::Time reversal of ultrasonic field allows a very efficient approach to focusing pulsed ultrasonic waves through lossless inhomogeneous media. Time reversal mirrors (TRM) are made of large transducer arrays, allowing the incident acoustic field to be sampled, time reversed and re-emitted. Time reversal processing permit...
journal_title:Ultrasonic imaging
pub_type: 杂志文章,评审
doi:10.1177/016173469601800202
更新日期:1996-04-01 00:00:00
abstract::Speckle noise is known to be signal-dependent in ultrasound imaging. Hence, separating noise from signal becomes a difficult task. This paper describes a wavelet-based method for reducing speckle noise. We derive from the model of the displayed ultrasound image the optimal wavelet-domain filter in the least mean-squar...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173460002200201
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journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173460002200303
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abstract::A narrow-band ultrasonic shear-wave imaging technique for estimating phase speed was applied to fresh and thermally damaged porcine liver in vitro. Two constitutive models were applied to the measurements to represent rheological behavior of the tissue and estimate the complex shear modulus at frequencies between 50 a...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173461003200405
更新日期:2010-10-01 00:00:00
abstract::Optimal transmit phasing has been proposed to increase contrast-to-tissue ratio (CTR) by relatively phasing the tissue and leakage harmonic components to cancel each other out for tissue-background suppression in harmonic imaging. Since most clinical systems are only equipped with a bipolar square-wave pulser, effecti...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173461003200103
更新日期:2010-01-01 00:00:00
abstract::In this paper, quantitative tomographic reconstructions of biological tissue are presented. First, the experimental setup and a hybrid filtered backpropagation (FBP) technique are briefly described. Using this technique, which includes exact backpropagation of data prior to reconstruction by means of the classical FBP...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173469401600102
更新日期:1994-01-01 00:00:00
abstract::Modern ultrasound Doppler systems are facing the problem of processing increasingly shorter data sets. Spectral analysis of the strongly nonstationary Doppler signal needs to shorten the analysis window while maintaining a low variance and high resolution spectrum. Color flow imaging requires estimation of the Doppler...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173469501700101
更新日期:1995-01-01 00:00:00
abstract::The liver has been hypothesized to have a unique arrangement of microvasculature that presents as an arrangement of quasiperiodic scatterers to an interrogating ultrasound pulse. The mean scatterer spacing (MSS) of these quasiperiodic scatterers has been proposed as a useful quantitative ultrasound biomarker for chara...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/0161734613511232
更新日期:2014-04-01 00:00:00
abstract::Tissues exhibiting quasi-periodic structures can be modeled as a collection of diffuse scatterers and coherent scatterers. The mean scatterer spacing (MSS) of coherent and quasi-periodic components is directly related to tissue microstructure and has become an important quantitative ultrasound (QUS) parameter in the c...
journal_title:Ultrasonic imaging
pub_type: 杂志文章,评审
doi:10.1177/0161734617692018
更新日期:2017-09-01 00:00:00
abstract::The propagation of pressure pulses of arbitrary time form in inhomogeneous attenuating media with characteristics similar to real biological tissues is considered. A mathematical model using the quasi-optical approximation is developed to solve the wave equation. Such a model proves to be convenient for computer reali...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173469301500106
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