Abstract:
:The aim of this study was to assess whether acoustic structure quantification (ASQ) can differentiate normal from pathological thyroid parenchyma in patients with diffuse autoimmune thyroid disease (AITD). We evaluated 83 subjects (72 [87%] women and 11 [13%] men) aged 19 to 94 years with a mean age of 53 years. We performed a prospective study (from March 2011 to November 2014) that included 43 (52%) patients with chronic autoimmune thyroiditis (CAT), 22 (26%) patients with Graves' disease (GD), and 18 (22%) healthy volunteers. The ASQ values were significantly lower in normal subjects than in subjects with CAT and GD (p < 0.001). In contrast, the differences between the GD and the CAT patients (p = 0.23) were not statistically significant. The optimal cutoff ASQ value for which the sum of sensitivity and specificity was the highest for the prediction of diffuse thyroid pathology was 103 (95% confidence interval = [0.79, 0.95]). At this cutoff value, the sensitivity was 83% and the specificity was 89%. Our findings suggest that ASQ is a useful method for the assessment of the thyroid in patients with AITD.
journal_name
Ultrason Imagingjournal_title
Ultrasonic imagingauthors
Zandieh S,Bernt R,Zwerina J,Haller J,Knoll P,Seyeddain O,Mirzaei Sdoi
10.1177/0161734615580766subject
Has Abstractpub_date
2016-03-01 00:00:00pages
137-47issue
2eissn
0161-7346issn
1096-0910pii
0161734615580766journal_volume
38pub_type
杂志文章abstract::Most methods for in vivo quantitation of ultrasound attenuation and backscatter are not available clinically because they rely upon acquiring and analyzing radio frequency (rf) echo signals. This paper describes a technique to estimate ultrasound attenuation and backscatter from B-mode image data. The video signal ana...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173469701900305
更新日期:1997-07-01 00:00:00
abstract::An algorithm for deconvolution of medical ultrasound images is presented. The procedure involves estimation of the basic one-dimensional ultrasound pulse, determining the ratio of the covariance of the noise to the covariance of the reflection signal, and finally deconvolution of the rf signal from the transducer. Usi...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173469301500204
更新日期:1993-04-01 00:00:00
abstract::Phased-array images have been obtained in vivo with a steered copolymer array operating at 2.5 MHz. The array was fabricated using 28 microns copolymer film, lambda/4 resonant at 21 MHz, which was bonded to a glass ceramic backing with a thin film bond. The 32 array elements were created by laser ablation of the conti...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173469201400302
更新日期:1992-07-01 00:00:00
abstract::Tissues exhibiting quasi-periodic structures can be modeled as a collection of diffuse scatterers and coherent scatterers. The mean scatterer spacing (MSS) of coherent and quasi-periodic components is directly related to tissue microstructure and has become an important quantitative ultrasound (QUS) parameter in the c...
journal_title:Ultrasonic imaging
pub_type: 杂志文章,评审
doi:10.1177/0161734617692018
更新日期:2017-09-01 00:00:00
abstract::In this paper, quantitative tomographic reconstructions of biological tissue are presented. First, the experimental setup and a hybrid filtered backpropagation (FBP) technique are briefly described. Using this technique, which includes exact backpropagation of data prior to reconstruction by means of the classical FBP...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173469401600102
更新日期:1994-01-01 00:00:00
abstract::Acoustic form factors have been used to model the frequency dependence of acoustic scattering in phantoms and tissues. This work demonstrates that a broad range of scatterer sizes, individually well represented by Faran theory or a Gaussian form factor, is not accurately described by a single effective scatterer from ...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/0161734614534399
更新日期:2015-01-01 00:00:00
abstract::Global and local attenuation coefficient estimations were performed in a phantom using a pulse echo method based on the rate of decay of zero crossing density. Focussed and unfocussed 3.5 MHz transducers were used. It was found that good global estimates could be made with either transducer over a 2:1 range of attenua...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173468500700202
更新日期:1985-04-01 00:00:00
abstract::Sidelobe contribution from off-axis targets degrades image quality in a coherent array imaging system. In ultrasound imaging, focusing errors resulting from sound-velocity inhomogeneities in human tissue--also known as phase aberrations reduce the coherence of the received signals and elevate the sidelobe level. This ...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173460502700205
更新日期:2005-04-01 00:00:00
abstract::In this work, we study linear array beamforming for vibro-acoustography systems. The goal of this research is to assess the feasibility of vibro-acoustography imaging systems based on linear arrays for clinical applications. The vibro-acoustography transducer is designed with two arrays driven by two continuous-wave o...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173460402600101
更新日期:2004-01-01 00:00:00
abstract::Ultrasonic coda wave analysis techniques localize defects in fields such as seismography and nondestructive testing. In medical ultrasound, these techniques might provide novel mapping of tissue properties in diseases characterized by local fibrosis. In this work, we present an approach for localizing variation in sca...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/0161734619899885
更新日期:2020-01-01 00:00:00
abstract::Two-dimensional echocardiography (2-D echo) imaging is a more attractive clinical tool than other modalities that either involve radiation exposure or are too slow to image heart motion in real-time. Computer-aided analysis of left ventricular(LV) wall motion provides quantitative parameters for diagnosis. This study ...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173469701900204
更新日期:1997-04-01 00:00:00
abstract::Anova and "dummy variables" least squares regression methods are used to investigate the dependence of ultrasound propagation velocity on the presence or absence of fat and on the rank ordered level of cirrhosis in fixed human liver. Cirrhosis is found to affect velocity in a nonlinear fashion, while fat depresses the...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173468300500306
更新日期:1983-07-01 00:00:00
abstract::Behavior and limitations of the sinc basis method have been discovered during simulation studies. An iterative row-action method (ART) is compared with a full-matrix, least-squares solution (QR decomposition) and the problem of multiple solutions is discussed. Knowledge of the spatial distribution of scattered field e...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173468901100103
更新日期:1989-01-01 00:00:00
abstract::A method has been developed for mapping density and ultrasonic speed in 1 mm thick slices of soft tissue with a resolution of about 1 mm. Tests using phantom sections have verified the accuracy and resolution of the ultrasonic speed maps. The method has been applied to breast tissues of three patients including tumors...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173469101300105
更新日期:1991-01-01 00:00:00
abstract::The propagation of pressure pulses of arbitrary time form in inhomogeneous attenuating media with characteristics similar to real biological tissues is considered. A mathematical model using the quasi-optical approximation is developed to solve the wave equation. Such a model proves to be convenient for computer reali...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173469301500106
更新日期:1993-01-01 00:00:00
abstract::In recent years, adaptive minimum-variance (MV) beamforming has been successfully applied to medical ultrasound imaging, resulting in simultaneous improvement in imaging resolution and contrast. MV has high resolution and hence can provide accurate estimates of the target locations. However, the MV amplitude estimates...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/0161734615600167
更新日期:2016-07-01 00:00:00
abstract::Acoustic radiation force impulse (ARFI) Surveillance of Subcutaneous Hemorrhage (ASSH) has been previously demonstrated to differentiate bleeding phenotype and responses to therapy in dogs and humans, but to date, the method has lacked experimental validation. This work explores experimental validation of ASSH in a po...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/0161734615617940
更新日期:2016-09-01 00:00:00
abstract::Our group has proposed the concept of subharmonic aided pressure estimation (SHAPE) utilizing microbubble-based ultrasound contrast agent signals for the noninvasive estimation of hydrostatic blood pressures. An experimental system for in vitro SHAPE was constructed based on two single-element transducers assembled co...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173461103300301
更新日期:2011-07-01 00:00:00
abstract::The aim of this study was to identify independent risk factors for thyroid cancer, establish an ultrasonographic multimodality diagnostic model for thyroid nodules, and explore the diagnostic value of the model. From November 2011 to February 2015, 307 patients with a total of 367 thyroid nodules underwent conventiona...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/0161734618815070
更新日期:2019-03-01 00:00:00
abstract::A new online signal processing technique is described to reduce speckle noise in ultrasound images. In the imaging system, a focused piston transducer is divided into thirty-two sectors. In the receive mode, parallel signal processing arranges the sectors into eight maltese crosses. The rf signals of the perpendicular...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173468801000301
更新日期:1988-07-01 00:00:00
abstract::An ultrasonic imaging and signal analysis system, combining a 3.5 MHz linear array B-scanner and an array processor, has been realized for a clinical liver tissue classification study. Based on the complete unprocessed rf data set of a real time B-image, local envelope power spectra averaged over interactively defined...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173469401600202
更新日期:1994-04-01 00:00:00
abstract::Conventional ultrasonic B-mode images qualitatively describe tissue structures but are unsuitable for quantitative analyses of scatterer properties. We have recently developed an ultrasonic parametric imaging technique based on the Nakagami statistical distribution that is able to quantify scatterer concentrations. Th...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173460803000202
更新日期:2008-04-01 00:00:00
abstract::Ultrasonic waveform data from a tissue-mimicking phantom containing low contrast targets was digitized, stored and processed prior to creating and displaying ultrasonic images. Speckle reduction was performed by digital filtering of the waveform data with appropriately spaced and weighted digital filters, prior to bot...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173468700900202
更新日期:1987-04-01 00:00:00
abstract::An autoregressive (AR) spectral estimation method was considered for the purpose of estimating scatterer size images. The variance and bias of the resulting estimates were compared with those using classical FFT periodograms for a range of input signal-to-noise ratios and echo-signal durations corresponding to various...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173469601800102
更新日期:1996-01-01 00:00:00
abstract::Regional anesthesia is preferred over general anesthesia for many surgical procedures; however, challenges associated with poor image guidance limit its widespread acceptance as a viable alternative. In B-mode ultrasound images, the current standard for guidance, nerves can be difficult to visualize due to their simil...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173460903100303
更新日期:2009-07-01 00:00:00
abstract::Generation of the second harmonic signal was studied for finite amplitude distortion based harmonic imaging. Acoustic field amplitudes along the range axis of a fixed focus transducer were measured using a PVDF needle hydrophone. Results indicated that on-axis amplitudes strongly depended on the f-number at both the f...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173469902100401
更新日期:1999-10-01 00:00:00
abstract::Muscle fatigue often occurs over a long period of exercise, and it can increase the risk of muscle injury. Evaluating the state of muscle fatigue can avoid unnecessary overtraining and injury of the muscle. Ultrasound imaging can non-invasively visualize muscle tissue in real-time. Image entropy is commonly used to ch...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/0161734620952683
更新日期:2020-11-01 00:00:00
abstract::For a class of scattering objects the mean separation between the scatterers is determined. Over a range of frequencies, ultrasonic back-scattered pressure signals are recorded. It is suggested to derive the mean spacing of an unknown scattering object by employing Fourier analysis and comparing the signal with signal...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173468300500405
更新日期:1983-10-01 00:00:00
abstract::The methods of statistical pattern recognition have been applied to the problem of in vivo ultrasonic characterization of breast disease in humans. Backscattered A-mode signals obtained from a commercial pulse imaging system were used to generate a large set of potentially useful features. Using statistical tests, a s...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173468300500107
更新日期:1983-01-01 00:00:00
abstract::The potential of using the phase derivative (PD) for echographic imaging was investigated. The PD data were calculated by four methods: zero crossing (ZCS) with squelch addition, analytic signal either with squelch addition (ASS) or with employment of a Wiener kernel (ASW), and unwrapped phase (UWP). The large peaks w...
journal_title:Ultrasonic imaging
pub_type: 杂志文章
doi:10.1177/016173468700900301
更新日期:1987-07-01 00:00:00