COPII vesicles get supersized by ubiquitin.

Abstract:

:Some proteins are too big to fit into conventional COPII-coated vesicles, which raises the question of how large cargo, such as procollagen fibrils, are exported from the endoplasmic reticulum. Jin et al. (2012) in Nature now report that the creation of oversized vesicles is facilitated by the ubiquitination of the COPII component Sec31p.

journal_name

Cell

journal_title

Cell

authors

Malhotra V

doi

10.1016/j.cell.2012.03.006

subject

Has Abstract

pub_date

2012-03-30 00:00:00

pages

20-1

issue

1

eissn

0092-8674

issn

1097-4172

pii

S0092-8674(12)00335-2

journal_volume

149

pub_type

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