Lysosomes nor Mice Move Forward without Borcs7.

Abstract:

:Lysosome function and position in the cytoplasm depends on the BORCS machinery, which tethers lysosomes to the kinesin microtubule motor. A recent paper of Snouwaert et al. in Cell Reports characterizes a mouse with a spontaneous mutation in the Borcs7 subunit, which causes axonal dystrophy and impaired motor function.

journal_name

Trends Cell Biol

journal_title

Trends in cell biology

authors

Joshi U,Houwman JA,van der Sluijs P

doi

10.1016/j.tcb.2018.08.002

subject

Has Abstract

pub_date

2018-10-01 00:00:00

pages

761-763

issue

10

eissn

0962-8924

issn

1879-3088

pii

S0962-8924(18)30140-5

journal_volume

28

pub_type

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