Excitement about inhibitory presynaptic terminals.

Abstract:

:Based on extrapolation from excitatory synapses, it is often assumed that depletion of the releasable pool of synaptic vesicles is the main factor underlying depression at inhibitory synapses. In this issue of Neuron, using subcellular patch-clamp recording from inhibitory presynaptic terminals, Kawaguchi and Sakaba (2015) show that at Purkinje cell-deep cerebellar nuclei neuron synapses, changes in presynaptic action potential waveform substantially contribute to synaptic depression.

journal_name

Neuron

journal_title

Neuron

authors

Vandael DH,Espinoza C,Jonas P

doi

10.1016/j.neuron.2015.03.006

subject

Has Abstract

pub_date

2015-03-18 00:00:00

pages

1149-51

issue

6

eissn

0896-6273

issn

1097-4199

pii

S0896-6273(15)00202-0

journal_volume

85

pub_type

评论,杂志文章

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