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A TREK to Translate Genetics to Mechanisms of Migraine.

Abstract：

:In this issue of Neuron, Royal et al. (2018) find that a mutant form of the TRESK ion channel linked to migraine undergoes alternative translation to produce an inhibitory protein that blocks TREK channels, leading to neuronal hyperexcitability and migraine in rodents.

journal_name

Neuron

journal_title

Neuron

authors

Hill RZ,Bautista DM

doi

10.1016/j.neuron.2018.12.034

subject

Has Abstract

pub_date

2019-01-16 00:00:00

pages

193-195

issue

2

eissn

0896-6273

issn

1097-4199

pii

S0896-6273(18)31154-1

journal_volume

101

pub_type

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