Abstract：
:Adolescence is often described as a period of heightened reactivity to emotions paired with reduced regulatory capacities, a combination suggested to contribute to risk-taking and susceptibility to peer influence during puberty. However, no longitudinal research has definitively linked these behavioral changes to underlying neural development. Here, 38 neurotypical participants underwent two fMRI sessions across the transition from late childhood (10 years) to early adolescence (13 years). Responses to affective facial displays exhibited a combination of general and emotion-specific changes in ventral striatum (VS), ventromedial PFC, amygdala, and temporal pole. Furthermore, VS activity increases correlated with decreases in susceptibility to peer influence and risky behavior. VS and amygdala responses were also significantly more negatively coupled in early adolescence than in late childhood while processing sad and happy versus neutral faces. Together, these results suggest that VS responses to viewing emotions may play a regulatory role that is critical to adolescent interpersonal functioning.
journal_name
Neuronjournal_title
Neuronauthors
Pfeifer JH,Masten CL,Moore WE 3rd,Oswald TM,Mazziotta JC,Iacoboni M,Dapretto Mdoi
10.1016/j.neuron.2011.02.019subject
Has Abstractpub_date
2011-03-10 00:00:00pages
1029-36issue
5eissn
0896-6273issn
1097-4199pii
S0896-6273(11)00117-6journal_volume
69pub_type
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