Generalizability of clinical trial results for generalized anxiety disorder to community samples.

abstract：BACKGROUND:Dimensional assessments are planned to be included as supplements to categorical diagnoses in DSM-V. The aim of this study was to examine the unidimensionality, reliability, validity, and clinical sensitivity of brief self-rated scales for specific anxiety disorders in an unselected German sample of consecut...

journal_title：Depression and anxiety

authors： Beesdo-Baum K,Klotsche J,Knappe S,Craske MG,Lebeau RT,Hoyer J,Strobel A,Pieper L,Wittchen HU

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Oligodendrocyte transcription factor 2 (OLIG2) is primarily concentrated in the brain and spinal cord ventricular zone, where this protein stimulates oligodendrocytes and specific neurons, determines motor neuron and oligodendrocyte differentiation, and sustains replication in early development. Recent studi...

journal_title：Depression and anxiety

authors： Zhang X,Liu J,Guo Y,Jiang W,Yu J

更新日期：2015-10-01 00:00:00

abstract：:Reports on the severity and reversibility of cognitive disturbances in major depression in the literature diverge due to methodological biases. The present study, using a precise methodology, examined attention and executive functions in 20 relatively young, depressed patients presenting a first or second episode of u...

journal_title：Depression and anxiety

authors： Constant EL,Adam S,Gillain B,Seron X,Bruyer R,Seghers A

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Although a large body of empirical research has examined negative psychological outcomes in older veterans, relatively little is known about the prevalence and determinants of psychological resilience in this population. METHODS:A nationally representative sample of 2,025 U.S. veterans aged 60 and older (me...

journal_title：Depression and anxiety

authors： Pietrzak RH,Cook JM

更新日期：2013-05-01 00:00:00

abstract：:Sensitization of stress-responsive neurobiological systems as a possible consequence of early adverse experience has been implicated in the pathophysiology of mood and anxiety disorders. In addition to early adversities, adulthood stressors are also known to precipitate the manifestation of these disorders. The presen...

journal_title：Depression and anxiety

authors： Heim C,Newport DJ,Wagner D,Wilcox MM,Miller AH,Nemeroff CB

更新日期：2002-01-01 00:00:00

abstract：:There are well-established sex differences in the prevalence of certain mental disorders. Work in animal models has provided us with an emerging understanding of the role that epigenetic factors play in establishing sex differences in the brain during development. Similarly, work in animal models, and a more limited b...

journal_title：Depression and anxiety

authors： Uddin M,Sipahi L,Li J,Koenen KC

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Psychosocial factors, including religious coping, consistently have been implicated in the expression of anxiety disorders. This study sought to investigate the relationship between religious coping on anxiety symptoms among a nonclinical sample of African American and European American young adults. METHOD...

journal_title：Depression and anxiety

authors： Chapman LK,Steger MF

更新日期：2010-03-01 00:00:00

abstract：:The selective serotonin reuptake inhibitors (SSRIs) are recognized as effective as and better tolerated than older antidepressant therapies and have become the drugs of choice in the treatment of mild to moderate depression. However, there is a clinical impression that the SSRIs are less effective than older therapies...

journal_title：Depression and anxiety

authors： Schatzberg AF

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Social anxiety disorder (SAD) is an incapacitating disorder running in families. Previous work associated social fearfulness with a failure to habituate, but the habituation response to neutral faces has, as of yet, not been investigated in patients with SAD and their family members concurrently. Here, we ex...

journal_title：Depression and anxiety

authors： Bas-Hoogendam JM,van Steenbergen H,Blackford JU,Tissier RLM,van der Wee NJA,Westenberg PM

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:The Generalized Anxiety Disorder Severity Scale (GADSS) is an interview rating scale designed specifically for assessing symptom severity of generalized anxiety disorder (GAD), which has demonstrated positive psychometric data in a sample of adult primary care patients with GAD and panic disorder. However, t...

journal_title：Depression and anxiety

authors： Weiss BJ,Calleo J,Rhoades HM,Novy DM,Kunik ME,Lenze EJ,Stanley MA

更新日期：2009-01-01 00:00:00

abstract：:Our objective was to evaluate parental risk factors for pediatric-onset panic disorder/agoraphobia (PD/AG) in offspring at high risk for PD/AG. Comparisons were made between parents with PD who had a child with PD or AG (N = 27) and parents with PD without children with PD or AG (N = 79). Comparisons were also made be...

journal_title：Depression and anxiety

authors： Biederman J,Petty C,Faraone SV,Hirshfeld-Becker DR,Henin A,Dougherty M,Lebel TJ,Pollack M,Rosenbaum JF

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:To compare the rates of low birth weight, preterm delivery and small for gestational age (SGA), in pregnancy outcomes among women who were exposed and nonexposed to antidepressants during pregnancy. METHODS:At The Motherisk Program, we analyzed pregnancy outcomes of 1,243 women in our database who took vario...

journal_title：Depression and anxiety

authors： Einarson A,Choi J,Einarson TR,Koren G

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Little is known regarding changes in the hypothalamic-pituitary-adrenal axis (HPA axis) of adolescent girls with and without posttraumatic stress disorder (PTSD) who have recently experienced sexual abuse. Therefore, in this pilot study, we utilized non-stressed home saliva collection three times a day for t...

journal_title：Depression and anxiety

authors： Keeshin BR,Strawn JR,Out D,Granger DA,Putnam FW

更新日期：2014-02-01 00:00:00

abstract：:Sleep deprivation for one night has been investigated as a treatment for depression since the first publications describing its antidepressant properties almost 30 years ago [Pflug and Tolle, 1971: Int Pharmacopsychiatry 6:187-196]. It remains a field of active research. It is the only intervention consistently demons...

journal_title：Depression and anxiety

authors： Ringel BL,Szuba MP

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Women are at an increased risk of depression and other mental health problems following rape. Various etiological factors for depression, including predisposing genetic factors, have been identified. Telomeres are repetitive nucleoprotein structures located at chromosomal ends that protect them from prematur...

journal_title：Depression and anxiety

authors： Malan S,Hemmings S,Kidd M,Martin L,Seedat S

更新日期：2011-12-21 00:00:00

abstract：OBJECTIVE:The impact of childhood adversity persists across the life course. This study aimed to investigate the associations of childhood adversity with the course, suicidality, and treatment outcomes of depressive disorders. METHOD:A total of 919 people with depressive disorders were recruited. Childhood adversities...

journal_title：Depression and anxiety

authors： Kim SW,Kang HJ,Kim SY,Kim JM,Yoon JS,Jung SW,Lee MS,Yim HW,Jun TY

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Although losses are important consequences of disasters, few epidemiological studies of disasters have assessed complicated grief (CG) and none assessed CG associated with losses other than death of loved one. METHODS:Data come from the baseline survey of the Hurricane Katrina Community Advisory Group, a re...

journal_title：Depression and anxiety

authors： Shear MK,McLaughlin KA,Ghesquiere A,Gruber MJ,Sampson NA,Kessler RC

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Brain-derived neurotrophic factor (BDNF) may have an important role in the pathophysiology of depression. Previous studies indicate that serum BDNF levels were lower in patients with depression and increased after treatment with antidepressants. However, results of studies on serum BDNF levels in remitted pa...

journal_title：Depression and anxiety

authors： Takebayashi N,Maeshima H,Baba H,Nakano Y,Satomura E,Kita Y,Namekawa Y,Nomoto H,Suzuki T,Arai H

更新日期：2012-09-01 00:00:00

abstract：:This study seeks to determine how panic disorder patients with anxiety and depression comorbidity differ from panic disorder patients without comorbidity at the time of presentation for treatment. One-hundred seventy-one panic disorder patients presenting for their initial assessment and treatment at the Payne Whitney...

journal_title：Depression and anxiety

authors： Apfeldorf WJ,Spielman LA,Cloitre M,Heckelman L,Shear MK

更新日期：2000-01-01 00:00:00

abstract：:The objective was to present naturalistic 1-year follow-up information of 96 child and adolescent outpatients with major depressive disorder who had been randomized in an 8-week double-blind, placebo-controlled trial of fluoxetine. Subjects were children and adolescents, ages 8-18 years, who were entered in a randomiz...

journal_title：Depression and anxiety

authors： Emslie GJ,Rush AJ,Weinberg WA,Kowatch RA,Carmody T,Mayes TL

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Exposure therapy, a gold-standard treatment for anxiety disorders, is assumed to work via extinction learning, but this has never been tested. Anxious individuals demonstrate extinction learning deficits, likely related to less ventromedial prefrontal cortex (vmPFC) and more amygdala activation, but the rela...

journal_title：Depression and anxiety

authors： Ball TM,Knapp SE,Paulus MP,Stein MB

更新日期：2017-03-01 00:00:00

abstract：:Electroconvulsive therapy (ECT) involves the use of electrical stimulation to elicit a series of generalized tonic-clonic seizures for therapeutic purposes and is the most effective treatment known for major depression. These treatments have significant neurophysiologic effects, many of which are manifest in the elect...

journal_title：Depression and anxiety

authors： Krystal AD,West M,Prado R,Greenside H,Zoldi S,Weiner RD

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND/OBJECTIVE:The role of the neuropeptide oxytocin (OT) in Borderline Personality Disorder (BPD) is poorly understood. It is particularly unknown how early experiences with caregivers moderate the action of OT in BPD. Here, we examined the association of plasma OT levels in BPD patients with the experience of c...

journal_title：Depression and anxiety

authors： Ebert A,Edel MA,Gilbert P,Brüne M

更新日期：2018-01-01 00:00:00

abstract：:The goal of this study was to discriminate subtypes of pediatric obsessive-compulsive disorder (OCD) among youth with and without a comorbid tic disorder. Seventy-four youth (M(age)=9.7+/-2.3 years) with a principal diagnosis of OCD, with (n=46) or without (n=28) a comorbid tic disorder, were assessed with a semi-stru...

journal_title：Depression and anxiety

authors： Storch EA,Stigge-Kaufman D,Marien WE,Sajid M,Jacob ML,Geffken GR,Goodman WK,Murphy TK

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Transdiagnostic cognitive-behavioral treatments for anxiety disorders have been gaining increased attention and empirical study in recent years. Despite this, research on transdiagnostic anxiety treatments has, to date, relied on open trials, or comparisons to waitlist conditions, published benchmarks, or re...

journal_title：Depression and anxiety

authors： Norton PJ,Barrera TL

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Following an acute burn injury, higher distress is consistently observed among individuals exhibiting a conflict between approach coping (e.g., processing) and avoidance coping (e.g., suppression) relative to those individuals who use only one of these methods. Study objectives were to determine if contradic...

journal_title：Depression and anxiety

authors： Fauerbach JA,Lawrence JW,Fogel J,Richter L,Magyar-Russell G,McKibben JB,McCann U

更新日期：2009-01-01 00:00:00

abstract：:An impediment to progress in mood disorders research is the lack of analytically valid and qualified diagnostic and treatment biomarkers. Consistent with the National Institute of Mental Health (NIMH)'s Research Domain Criteria (RDoC) initiative, the lack of diagnostic biomarkers has precluded us from moving away from...

journal_title：Depression and anxiety

authors： Niciu MJ,Mathews DC,Nugent AC,Ionescu DF,Furey ML,Richards EM,Machado-Vieira R,Zarate CA Jr

更新日期：2014-04-01 00:00:00

abstract：:There is an urgent need for more rapidly effective pharmacotherapies for major depressive disorder and bipolar disorder (BP) that are efficacious and tolerable for depressed patients who respond poorly to conventional treatments. Multiple controlled trials have now demonstrated a rapid, nonsustained antidepressive res...

journal_title：Depression and anxiety

authors： Bobo WV,Vande Voort JL,Croarkin PE,Leung JG,Tye SJ,Frye MA

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Self-esteem is a major concern in mood disorders. Low self-esteem is a symptom of depressive disorders and is considered by some to be a predictor for relapse, whereas high self-esteem seems to buffer against depression. Recently, Competitive Memory Training (COMET) has shown to be effective for the enhancem...

journal_title：Depression and anxiety

authors： Korrelboom K,Maarsingh M,Huijbrechts I

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Patients with obsessive-compulsive disorder (OCD) experience abnormally high levels of uncertainty, and unpredictability is evaluated negatively and not well tolerated. The current study examined neural correlates of attentional processing in response to experimentally induced uncertainty in OCD. METHODS:Tw...

journal_title：Depression and anxiety

authors： Dieterich R,Endrass T,Kathmann N

更新日期：2017-11-01 00:00:00