Abstract:
OBJECTIVE:To compare the rates of low birth weight, preterm delivery and small for gestational age (SGA), in pregnancy outcomes among women who were exposed and nonexposed to antidepressants during pregnancy. METHODS:At The Motherisk Program, we analyzed pregnancy outcomes of 1,243 women in our database who took various antidepressants during their pregnancy. Nine hundred and twenty-eight of these women and 928 nonexposed women who delivered a live born infant were matched for age, (+/-2 years), smoking and alcohol use and specific pregnancy outcomes were compared between the two groups. RESULTS:There were 82 (8.8%) preterm deliveries in the antidepressant group and 50 (5.4%) in the comparison group. OR: 1.7 (95% CI: 1.18-2.45). There were 89 (9.6%) in the antidepressant group and 76 (8.2%) in the comparison group who delivered babies evaluated as SGA; OR: 1.19 (95% CI: 0.86-1.64). The mean birth weight in the antidepressant group was 3,449+/-591 g and 3,455+/-515 g in the comparison group (P=.8). CONCLUSION:The use of antidepressants in pregnancy appears to be associated with a small, but statistically significant increased rate in the incidence of preterm births, confirming results from several other studies. It is difficult to ascertain whether this small increased rate of preterm births is confounded by depression, antidepressants, or both. However, we did not find a statistically significant difference in the incidence of SGA or lower birth weight. This information adds to limited data available in the literature regarding these outcomes following the use of antidepressants in pregnancy.
journal_name
Depress Anxietyjournal_title
Depression and anxietyauthors
Einarson A,Choi J,Einarson TR,Koren Gdoi
10.1002/da.20598subject
Has Abstractpub_date
2010-01-01 00:00:00pages
35-8issue
1eissn
1091-4269issn
1520-6394journal_volume
27pub_type
杂志文章abstract::Since the introduction of the concept of social anxiety (or phobia) to the American nosological system in DSM-III (1980), it has become increasingly apparent that the condition is also prevalent in other cultures. In Japan, for example, the condition, called taijinkyofusho (usually abbreviated as TKS in English), is w...
journal_title:Depression and anxiety
pub_type: 杂志文章,评审
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journal_title:Depression and anxiety
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journal_title:Depression and anxiety
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journal_title:Depression and anxiety
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journal_title:Depression and anxiety
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journal_title:Depression and anxiety
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journal_title:Depression and anxiety
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journal_title:Depression and anxiety
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journal_title:Depression and anxiety
pub_type: 杂志文章
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journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20381
更新日期:2008-01-01 00:00:00
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journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/(sici)1520-6394(1998)8:2<65::aid-da4>3.0.c
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journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22286
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journal_title:Depression and anxiety
pub_type: 杂志文章
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更新日期:2019-07-01 00:00:00
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journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20366
更新日期:2008-01-01 00:00:00
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journal_title:Depression and anxiety
pub_type: 杂志文章
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journal_title:Depression and anxiety
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journal_title:Depression and anxiety
pub_type: 杂志文章,评审
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journal_title:Depression and anxiety
pub_type: 杂志文章,评审
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更新日期:2009-01-01 00:00:00
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journal_title:Depression and anxiety
pub_type: 临床试验,杂志文章,多中心研究
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更新日期:2014-08-01 00:00:00
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journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/1520-6394(2000)12:1<1::AID-DA1>3.0.CO;2-W
更新日期:2000-01-01 00:00:00
abstract::Numerous studies have examined the acute antidepressant effects of prefrontal transcranial magnetic stimulation (TMS). However, there is little information on whether TMS can be used as a maintenance treatment to maintain normal mood once subjects have responded. We describe seven adults with bipolar depression who re...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20027
更新日期:2004-01-01 00:00:00
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journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22893
更新日期:2019-09-01 00:00:00
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journal_title:Depression and anxiety
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更新日期:2020-08-12 00:00:00
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journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20834
更新日期:2011-08-01 00:00:00
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journal_title:Depression and anxiety
pub_type: 杂志文章,meta分析
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pub_type: 杂志文章
doi:10.1002/da.20809
更新日期:2011-05-01 00:00:00