Developing biomarkers in mood disorders research through the use of rapid-acting antidepressants.

abstract：:The chronicity and morbidity of established post-traumatic stress disorder (PTSD) has stimulated interest in recognizing and understanding the early development of the disorder. Acute stress disorder, a new diagnosis intended to facilitate early case detection, rests on the occurrence of dissociative reactions. It rem...

journal_title：Depression and anxiety

authors： Mellman TA,David D,Bustamante V,Fins AI,Esposito K

更新日期：2001-01-01 00:00:00

abstract：:Despite emotion regulation being altered in patients with obsessive-compulsive disorder (OCD), no studies have investigated its relation to multimodal amygdala connectivity. We compared corticolimbic functional and structural connectivity between OCD patients and healthy controls (HCs), and correlated this with the di...

journal_title：Depression and anxiety

authors： Picó-Pérez M,Ipser J,Taylor P,Alonso P,López-Solà C,Real E,Segalàs C,Roos A,Menchón JM,Stein DJ,Soriano-Mas C

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Bipolar disorder (BD) is highly familial, but studies have yet to examine preschoolers at risk for BD using standardized, developmentally appropriate clinical assessment tools. We used such methods to test whether preschoolers at familial risk for BD have more observed difficulty modulating emotions and beha...

journal_title：Depression and anxiety

authors： Tseng WL,Guyer AE,Briggs-Gowan MJ,Axelson D,Birmaher B,Egger HL,Helm J,Stowe Z,Towbin KA,Wakschlag LS,Leibenluft E,Brotman MA

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Chronotype is an individual's preferred timing of sleep and activity, and is often referred to as a later chronotype (or evening-type) or an earlier chronotype (or morning-type). Having an evening chronotype is associated with more severe depressive and anxiety symptoms. Based on these findings it is has bee...

journal_title：Depression and anxiety

authors： Druiven SJM,Hovenkamp-Hermelink JHM,Knapen SE,Kamphuis J,Haarman BCM,Penninx BWJH,Antypa N,Meesters Y,Schoevers RA,Riese H

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Although numerous studies have examined the role of latent predispositions to internalizing and externalizing disorders in the structure of comorbidity among common mental disorders, none examined latent predispositions in predicting development of comorbidity. METHODS:A novel method was used to study the r...

journal_title：Depression and anxiety

authors： Kessler RC,Cox BJ,Green JG,Ormel J,McLaughlin KA,Merikangas KR,Petukhova M,Pine DS,Russo LJ,Swendsen J,Wittchen HU,Zaslavsky AM

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Previous work on gene-environment (GxE) interplay concerning anxiety has focused on the interaction of 5-HTTLPR with childhood adversities or traumatic events whereas the impact of recent stressors is understudied, as is the integration of resilience. The current study aimed to investigate the interactive ef...

journal_title：Depression and anxiety

authors： Ollmann TM,Voss C,Venz J,Seidl E,Hoyer J,Kische H,Pieper L,Schiele MA,Domschke K,Beesdo-Baum K

更新日期：2020-10-14 00:00:00

abstract：BACKGROUND:Investigations of gene-environment interaction (GxE) in depression have implicated a polymorphism in the promoter region of the serotonin transporter gene (5-HTTLPR) as a moderator of the stress-depression relationship. However, recent evidence for 5-HTTLPR GxE in depression has been inconsistent. This study...

journal_title：Depression and anxiety

authors： Conway CC,Hammen C,Brennan PA,Lind PA,Najman JM

更新日期：2010-08-01 00:00:00

abstract：:Electroconvulsive therapy (ECT) involves the use of electrical stimulation to elicit a series of generalized tonic-clonic seizures for therapeutic purposes and is the most effective treatment known for major depression. These treatments have significant neurophysiologic effects, many of which are manifest in the elect...

journal_title：Depression and anxiety

authors： Krystal AD,West M,Prado R,Greenside H,Zoldi S,Weiner RD

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Previous studies have indicated a high prevalence of generalized anxiety disorder (GAD) in women with anorexia nervosa (AN). However, the shared genetic and environmental components of these disorders have not been explored. This study seeks to elucidate the shared genetic and environmental components betwee...

journal_title：Depression and anxiety

authors： Dellava JE,Kendler KS,Neale MC

更新日期：2011-08-01 00:00:00

abstract：:Paruresis is characterized by the fear of not being able to urinate in public bathrooms and has been classified by some to be a sub-type of social anxiety disorder (social phobia). Despite the existence of a consumer advocacy organization, the "Intentional Paruresis Association (www.paruresis.org)," there is sparse li...

journal_title：Depression and anxiety

authors： Vythilingum B,Stein DJ,Soifer S

更新日期：2002-01-01 00:00:00

abstract：:Our objective was to evaluate parental risk factors for pediatric-onset panic disorder/agoraphobia (PD/AG) in offspring at high risk for PD/AG. Comparisons were made between parents with PD who had a child with PD or AG (N = 27) and parents with PD without children with PD or AG (N = 79). Comparisons were also made be...

journal_title：Depression and anxiety

authors： Biederman J,Petty C,Faraone SV,Hirshfeld-Becker DR,Henin A,Dougherty M,Lebel TJ,Pollack M,Rosenbaum JF

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:The past decade of research has seen considerable interest in computer-based approaches designed to directly target cognitive mechanisms of anxiety, such as attention bias modification (ABM). METHODS:By pooling patient-level datasets from randomized controlled trials of ABM that utilized a dot-probe trainin...

journal_title：Depression and anxiety

authors： Price RB,Kuckertz JM,Amir N,Bar-Haim Y,Carlbring P,Wallace ML

更新日期：2017-12-01 00:00:00

abstract：:Depressive symptoms, due either major depression or clinically significant, subsyndromal depression, occur commonly in the course of Alzheimer's disease. For a variety of clinical and methodological reasons, this remains an area that begs for new investigation. At the very least, these depressive symptoms should be vi...

journal_title：Depression and anxiety

authors： Tune LE

更新日期：1998-01-01 00:00:00

abstract：:Clinical commentators widely interpret crying as a sign of depressed mood. However, there is virtually no empirical data on this topic, and the evidence that mood disorders alter crying is surprisingly weak. This study compared mood disordered patients to a nonpsychiatric reference group on the frequency, antecedents,...

journal_title：Depression and anxiety

authors： Rottenberg J,Cevaal A,Vingerhoets AJ

更新日期：2008-01-01 00:00:00

abstract：:The current study describes the validation of a new cognitive assessment measure for social phobia, entitled the Appraisal of Social Concerns (ASC). Item content is relevant to a range of social situations. The ASC can be used to tailor interventions to patients' idiosyncratic concerns. Data are presented from both cl...

journal_title：Depression and anxiety

authors： Telch MJ,Lucas RA,Smits JA,Powers MB,Heimberg R,Hart T

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Major depressive disorder (MDD) and smoking are major public health problems and epidemiologically strongly associated. However, the relationship between smoking and depression and whether this is influenced by common confounding factors remain unclear, in part due to limited longitudinal data on covariation...

journal_title：Depression and anxiety

authors： Holma IA,Holma KM,Melartin TK,Ketokivi M,Isometsä ET

更新日期：2013-06-01 00:00:00

abstract：:There is abundant evidence for abnormalities of the norepinephrine (NE) and serotonin (5HT) neurotransmitter systems in depression and anxiety disorders. The majority of evidence supports underactivation of serotonergic function and complex dysregulation of noradrenergic function, most consistent with overactivation o...

journal_title：Depression and anxiety

authors： Ressler KJ,Nemeroff CB

更新日期：2000-01-01 00:00:00

abstract：:We assessed psychophysiological responses to imagery of traumatic events, panic attacks, and loss of vigilance (i.e., being hypnotized) in participants diagnosed with panic disorder. Participants were either currently experiencing nocturnal panic or daytime panics only. It was hypothesized that nocturnal panickers wou...

journal_title：Depression and anxiety

authors： Tsao JC,Craske MG

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Exaggerated amygdala activation to threatening faces has been detected in adults and children with anxiety disorders, compared to healthy comparison (HC) subjects. However, the profile of amygdala activation in response to facial expressions in obsessive-compulsive disorder (OCD) may be a distinguishing feat...

journal_title：Depression and anxiety

authors： Britton JC,Stewart SE,Killgore WD,Rosso IM,Price LM,Gold AL,Pine DS,Wilhelm S,Jenike MA,Rauch SL

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Theory and research suggest that generalized anxiety disorder (GAD) is associated with diminished quality of life and restriction in valued action. The purpose of this study was to examine the relevance of values-consistent behavior (valued action) in understanding the impairment in quality of life in GAD. ...

journal_title：Depression and anxiety

authors： Michelson SE,Lee JK,Orsillo SM,Roemer L

更新日期：2011-05-01 00:00:00

abstract：:Functional impairment might amplify suicide risk in later life. A positive view of the future may reduce this risk. We tested the hypothesis that hopelessness and positive future orientation moderate the association between functional status and suicide ideation in a sample of 136 patients, 55 years of age or older, i...

journal_title：Depression and anxiety

authors： Hirsch JK,Duberstein PR,Conner KR,Heisel MJ,Beckman A,Franus N,Conwell Y

更新日期：2007-01-01 00:00:00

abstract：:Ninety-three patients, including 47 patients with Generalized Anxiety Disorder (GAD) and 46 patients with Major Depression (MD), were entered into recent clinical trials. Clinicians acknowledge that during the initial screening process, clear separation between depressed and anxious patients may be difficult. By using...

journal_title：Depression and anxiety

authors： Freeman AM 3rd,Kablinger AS,Rolland PD,Brannon GE

更新日期：1999-01-01 00:00:00

abstract：:The growing recognition and occurrence of traumatic exposure in the general population has given increased salience to the need to understand the concept of resilience. More than just the "flip side" of a risk factor, the notion of resilience encompasses psychological and biological characteristics, intrinsic to an in...

journal_title：Depression and anxiety

authors： Hoge EA,Austin ED,Pollack MH

更新日期：2007-01-01 00:00:00

abstract：:A National Institutes of Health (National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; National Institute on Aging) working group meeting focused on the non-motor aspects of Parkinson's disease (PD). Below is the summary of the meeting presentations and recommendations for a res...

journal_title：Depression and anxiety

authors： Edwards E,Kitt C,Oliver E,Finkelstein J,Wagster M,McDonald WM

更新日期：2002-01-01 00:00:00

abstract：:Pramipexole, a dopamine D2 receptor agonist, was tested in 174 patients with major depression, with or without melancholia and without psychotic features. Three daily dose levels (0.375 mg, 1.0 mg, and 5.0 mg) were compared to fluoxetine (Prozac) at 20 mg and placebo in a randomized, double-blind, parallel-group study...

journal_title：Depression and anxiety

authors： Corrigan MH,Denahan AQ,Wright CE,Ragual RJ,Evans DL

更新日期：2000-01-01 00:00:00

abstract：:It is well known that insomnia is more frequent in women than in men throughout all age groups. In this respect insomnia resembles other psychiatric disorders that occur more frequently in women such as anxiety and depressive disorders. Since insomnia is frequently a symptom of anxiety and depression, it remains an op...

journal_title：Depression and anxiety

authors： Voderholzer U,Al-Shajlawi A,Weske G,Feige B,Riemann D

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Treatment utilization/costs and work performance for persons with major depressive disorder (MDD) by severity of illness is not well documented. METHODS:Using National Comorbidity Survey-Replication (2001-2002) data, US workforce respondents (n=4,465) were classified by clinical severity (not clinically dep...

journal_title：Depression and anxiety

authors： Birnbaum HG,Kessler RC,Kelley D,Ben-Hamadi R,Joish VN,Greenberg PE

更新日期：2010-01-01 00:00:00

abstract：:This study replicated the factor structure of the Parental Bonding Instrument (PBI), and explored the relationships of PBI scores to demographic variables. We investigated the association between parental bonding in the parents measured by the PBI, and lifetime history of depression in their children assessed by the I...

journal_title：Depression and anxiety

authors： Uehara T,Sato T,Sakado K,Someya T

更新日期：1998-01-01 00:00:00

abstract：:This study assessed striatal dopamine 1 (D1) receptor binding in patients with major depressive disorder and anger attacks (MDD+A) and healthy volunteers. We used positron emission tomography with [(11)C]SCH 23,390 to compare 10 patients with MDD+A to 10 healthy volunteers. [(11)C]SCH 23,390 binding in bilateral stria...

journal_title：Depression and anxiety

authors： Dougherty DD,Bonab AA,Ottowitz WE,Livni E,Alpert NM,Rauch SL,Fava M,Fischman AJ

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Psychosocial factors, including religious coping, consistently have been implicated in the expression of anxiety disorders. This study sought to investigate the relationship between religious coping on anxiety symptoms among a nonclinical sample of African American and European American young adults. METHOD...

journal_title：Depression and anxiety

authors： Chapman LK,Steger MF

更新日期：2010-03-01 00:00:00