Comparison of pramipexole, fluoxetine, and placebo in patients with major depression.

abstract：BACKGROUND:Parental mental disorders have been shown to predict offspring's mental health problems. We examined whether pathways from parental mental disorders to offspring's psychiatric work disability in early adulthood are mediated through offspring's mental disorders and social disadvantage in adolescence. METHODS...

journal_title：Depression and anxiety

authors： Halonen JI,Merikukka M,Gissler M,Kerkelä M,Virtanen M,Ristikari T,Hiilamo H,Lallukka T

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Childhood maltreatment has been associated with symptom severity, reduced quality of life, and impaired functioning in adults with social anxiety disorder (SAD). No study has investigated how childhood maltreatment impacts pharmacotherapy outcomes in this population, despite evidence for such a link in depre...

journal_title：Depression and anxiety

authors： Bruce LC,Heimberg RG,Blanco C,Schneier FR,Liebowitz MR

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Previous work has shown that inhibition of fear is impaired in posttraumatic stress disorder (PTSD) resulting from both civilian and combat trauma. The purpose of the present study was to investigate the inhibition of learned fear in traumatized individuals diagnosed with either acute stress disorder (ASD) o...

journal_title：Depression and anxiety

authors： Jovanovic T,Sakoman AJ,Kozarić-Kovačić D,Meštrović AH,Duncan EJ,Davis M,Norrholm SD

更新日期：2013-03-01 00:00:00

abstract：:A reclassification of obsessive-compulsive disorder (OCD) into a new diagnostic category spectrum of "obsessive-compulsive spectrum disorders" (OCSDs) has recently been proposed, with considerable debate, for the forthcoming Diagnostic and Statistical Manual-Fifth Edition (DSM-V). This paper provides a critical analys...

journal_title：Depression and anxiety

authors： Storch EA,Abramowitz J,Goodman WK

更新日期：2008-01-01 00:00:00

abstract：:This review examines the question of whether there should be a cluster of disorders, including the adjustment disorders (ADs), acute stress disorder (ASD), posttraumatic stress disorder (PTSD), and the dissociative disorders (DDs), in a section devoted to abnormal responses to stress and trauma in the DSM-5. Environme...

journal_title：Depression and anxiety

authors： Friedman MJ,Resick PA,Bryant RA,Strain J,Horowitz M,Spiegel D

更新日期：2011-09-01 00:00:00

abstract：:This study assessed striatal dopamine 1 (D1) receptor binding in patients with major depressive disorder and anger attacks (MDD+A) and healthy volunteers. We used positron emission tomography with [(11)C]SCH 23,390 to compare 10 patients with MDD+A to 10 healthy volunteers. [(11)C]SCH 23,390 binding in bilateral stria...

journal_title：Depression and anxiety

authors： Dougherty DD,Bonab AA,Ottowitz WE,Livni E,Alpert NM,Rauch SL,Fava M,Fischman AJ

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVES:To explore the anxiolytic effects of a 4-month randomized, placebo-controlled trial of exercise and antidepressant medication in patients with major depressive disorder (MDD), and to examine the potential modifying effects of anxiety in treating depressive symptoms. MATERIALS AND METHODS:In this secondary a...

journal_title：Depression and anxiety

authors： Blumenthal JA,Babyak MA,Craighead WE,Davidson J,Hinderliter A,Hoffman B,Doraiswamy PM,Sherwood A

更新日期：2020-08-12 00:00:00

abstract：BACKGROUND:Complicated grief (CG) is a bereavement-specific syndrome distinct from but commonly comorbid with posttraumatic stress disorder (PTSD). While bereavement is common among military personnel (Simon et al., 2018), there is little research on the impact of CG comorbidity on PTSD treatment outcomes. METHODS:To ...

journal_title：Depression and anxiety

authors： Simon NM,Hoeppner SS,Lubin RE,Robinaugh DJ,Malgaroli M,Norman SB,Acierno R,Goetter EM,Hellberg SN,Charney ME,Bui E,Baker AW,Smith E,Kim HM,Rauch SAM

更新日期：2020-01-01 00:00:00

abstract：:The goal of this study was to discriminate subtypes of pediatric obsessive-compulsive disorder (OCD) among youth with and without a comorbid tic disorder. Seventy-four youth (M(age)=9.7+/-2.3 years) with a principal diagnosis of OCD, with (n=46) or without (n=28) a comorbid tic disorder, were assessed with a semi-stru...

journal_title：Depression and anxiety

authors： Storch EA,Stigge-Kaufman D,Marien WE,Sajid M,Jacob ML,Geffken GR,Goodman WK,Murphy TK

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Women are at an increased risk of depression and other mental health problems following rape. Various etiological factors for depression, including predisposing genetic factors, have been identified. Telomeres are repetitive nucleoprotein structures located at chromosomal ends that protect them from prematur...

journal_title：Depression and anxiety

authors： Malan S,Hemmings S,Kidd M,Martin L,Seedat S

更新日期：2011-12-21 00:00:00

abstract：BACKGROUND:Prevention of PTSD requires identification of subpopulations contributing most to the population burden of PTSD. This study examines the relative contribution of subthreshold PTSD and probable PTSD on future PTSD in a representative military cohort. METHODS:We analyze data on 3,457 U.S. National Guard membe...

journal_title：Depression and anxiety

authors： Fink DS,Gradus JL,Keyes KM,Calabrese JR,Liberzon I,Tamburrino MB,Cohen GH,Sampson L,Galea S

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Socioeconomic deprivation is associated with higher prevalence of mental health problems; however, the influence of socioeconomic status (SES) on psychological therapy outcomes is as yet unclear. AIM:To review published evidence on the association between indicators of SES (income, education, employment, ne...

journal_title：Depression and anxiety

authors： Finegan M,Firth N,Wojnarowski C,Delgadillo J

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Fear overgeneralization is a central feature of anxiety disorders and can lead to excessive avoidance. As perceptual discrimination is a key component of fear overgeneralization, a perceptual discrimination training task was created aimed at improving perceptual discrimination and reducing fear overgeneraliz...

journal_title：Depression and anxiety

authors： Ginat-Frolich R,Klein Z,Aderka IM,Shechner T

更新日期：2019-09-01 00:00:00

abstract：:Social support is proposed to attenuate behavioral consequences of exposure to uncontrollable stressors. To test this possibility, we compared the effects of two post-stress housing conditions, in pairs or in groups of 10-12 animals per cage, on the behavior of rats tested in the elevated plus-maze (EPM) 24 hr after s...

journal_title：Depression and anxiety

authors： Andrade CS,Guimarães FS

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Maintenance of gains with cognitive-behavioral treatment for trichotillomania (TTM) has historically been problematic. METHODS:We conducted follow-up assessments 3 and 6 months after completion of a 3-month maintenance phase on 10 individuals with DSM-IV-TR TTM who participated in an open trial of a dialect...

journal_title：Depression and anxiety

authors： Keuthen NJ,Rothbaum BO,Falkenstein MJ,Meunier S,Timpano KR,Jenike MA,Welch SS

更新日期：2011-04-01 00:00:00

abstract：:Although the use of telemedicine in psychiatry has a long history in providing clinical care to patients, its use in clinical trials research has not yet been commonly employed. Telemedicine allows for the remote assessment of study patients, which could be done by a centralized, highly calibrated, and impartial cohor...

journal_title：Depression and anxiety

authors： Kobak KA,Williams JB,Jeglic E,Salvucci D,Sharp IR

更新日期：2008-01-01 00:00:00

abstract：:This study was designed to investigate the efficacy of the antidepressant fluvoxamine in the treatment of combat-related post-traumatic stress disorder (PTSD). Fifteen veterans with combat-related PTSD and no other psychiatric diagnosis except depression were recruited to participate in a 14-week open-label study of f...

journal_title：Depression and anxiety

authors： Escalona R,Canive JM,Calais LA,Davidson JR

更新日期：2002-01-01 00:00:00

abstract：:Treatment-resistant depression (TRD) in adolescents is prevalent and impairing. We here review the definition, prevalence, clinical significance, risk factors, and management of TRD in adolescents. Risk factors associated with TRD include characteristics of depression (severity, level of hopelessness, and suicidal ide...

journal_title：Depression and anxiety

authors： Maalouf FT,Atwi M,Brent DA

更新日期：2011-11-01 00:00:00

abstract：:Our objective was to evaluate parental risk factors for pediatric-onset panic disorder/agoraphobia (PD/AG) in offspring at high risk for PD/AG. Comparisons were made between parents with PD who had a child with PD or AG (N = 27) and parents with PD without children with PD or AG (N = 79). Comparisons were also made be...

journal_title：Depression and anxiety

authors： Biederman J,Petty C,Faraone SV,Hirshfeld-Becker DR,Henin A,Dougherty M,Lebel TJ,Pollack M,Rosenbaum JF

更新日期：2005-01-01 00:00:00

abstract：:This study sought to describe clinical and demographic characteristics differentiating patients with DSM-III-R simple phobias comorbid with one or more of five DSM-III-R index anxiety disorders as compared with those with the index diagnoses alone. From 711 subjects participating in a multicenter, longitudinal, natura...

journal_title：Depression and anxiety

authors： Goisman RM,Allsworth J,Rogers MP,Warshaw MG,Goldenberg I,Vasile RG,Rodriguez-Villa F,Mallya G,Keller MB

更新日期：1998-01-01 00:00:00

abstract：:The psychometric properties of the Social Phobia Anxiety Inventory (SPAI) were assessed in a sample of participants who either had a primary diagnosis of social phobia or were normal volunteers. Positive evidence was obtained on the SPAI's concurrent and predictive convergent validity: it was significantly correlated ...

journal_title：Depression and anxiety

authors： Rodebaugh TL,Chambless DL,Terrill DR,Floyd M,Uhde T

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Controversy surrounds the question of whether agoraphobia (AG) exists as an independent diagnostic entity apart from panic. In favor of this position, AG without panic disorder (PD) in parents was found being unrelated to offsprings' risk for AG or PD, albeit it may enhance the familial transmission of PD (N...

journal_title：Depression and anxiety

authors： Knappe S,Beesdo-Baum K,Nocon A,Wittchen HU

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Vilazodone, a selective serotonin reuptake inhibitor and 5-HT1A receptor partial agonist, is approved for treating major depressive disorder in adults. This study (NCT01629966 ClinicalTrials.gov) evaluated the efficacy and safety of vilazodone in adults with generalized anxiety disorder (GAD). METHODS:A mul...

journal_title：Depression and anxiety

authors： Gommoll C,Durgam S,Mathews M,Forero G,Nunez R,Tang X,Thase ME

更新日期：2015-06-01 00:00:00

abstract：:Anxiety disorders are among the most common psychiatric disorders, affecting one in four individuals over a lifetime. Although our understanding of the etiology of these disorders is incomplete, familial and genetic factors are established risk factors. However, identifying the specific casual genes has been difficult...

journal_title：Depression and anxiety

authors： Smoller JW,Block SR,Young MM

更新日期：2009-01-01 00:00:00

abstract：:The selective serotonin reuptake inhibitors (SSRIs) are recognized as effective as and better tolerated than older antidepressant therapies and have become the drugs of choice in the treatment of mild to moderate depression. However, there is a clinical impression that the SSRIs are less effective than older therapies...

journal_title：Depression and anxiety

authors： Schatzberg AF

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Recent research suggests that posttraumatic stress disorder (PTSD) is associated with altered amygdala and hippocampal resting-state functional connectivity (rsFC). However, less research has examined whether Prolonged Exposure (PE), a first line exposure-based treatment for PTSD, has the potential to alter ...

journal_title：Depression and anxiety

authors： Zhu X,Suarez-Jimenez B,Lazarov A,Helpman L,Papini S,Lowell A,Durosky A,Lindquist MA,Markowitz JC,Schneier F,Wager TD,Neria Y

更新日期：2018-10-01 00:00:00

abstract：:Depressed patients who rapidly metabolize antidepressants may be common, and may not respond to even high doses of antidepressants if subtherapeutic plasma levels are produced. Rapid metabolizers (RMs) are identifiable if patients are on tricyclic antidepressants (TCAs), and TCA plasma levels (commonly available) are ...

journal_title：Depression and anxiety

authors： Kraus RP,Diaz P,McEachran A

更新日期：1996-01-01 00:00:00

abstract：:This study explores the psychometric properties of the Portuguese version of Corah's Dental Anxiety Scale (DAS), an instrument designed to assess the manifestations of dental anxiety. The DAS has been translated into several languages, but no adaptation and reliability analysis of the Portuguese version of the scale h...

journal_title：Depression and anxiety

authors： Hu LW,Gorenstein C,Fuentes D

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:There is ample evidence of the efficacy of cognitive-behavioral therapy (CBT) for depression in adolescents, including Puerto Rican adolescents. However, there is still a high percentage of adolescents who do not respond to a standard "dose" of 12 sessions of CBT. This clinical case study explores the charac...

journal_title：Depression and anxiety

authors： Jiménez Chafey MI,Bernal G,Rosselló J

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Although losses are important consequences of disasters, few epidemiological studies of disasters have assessed complicated grief (CG) and none assessed CG associated with losses other than death of loved one. METHODS:Data come from the baseline survey of the Hurricane Katrina Community Advisory Group, a re...

journal_title：Depression and anxiety

authors： Shear MK,McLaughlin KA,Ghesquiere A,Gruber MJ,Sampson NA,Kessler RC

更新日期：2011-08-01 00:00:00