Abstract:
:Although numerous theoretical models implicate the prefrontal cortex (PFC) as a source of top-down control signals, empirical support is limited. In this review, we highlight direct evidence for this view of PFC function and discuss several lines of other supportive findings. Most evidence to-date is only suggestive due to methodological challenges in tracking the spatiotemporal dynamics of cortical networks. However, we discuss several promising approaches that could further our understanding of the role of the PFC in goal-directed behavior.
journal_name
Neuronjournal_title
Neuronauthors
Miller BT,D'Esposito Mdoi
10.1016/j.neuron.2005.11.002subject
Has Abstractpub_date
2005-11-23 00:00:00pages
535-8issue
4eissn
0896-6273issn
1097-4199pii
S0896-6273(05)00936-0journal_volume
48pub_type
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