Abstract:
:Schizosaccharomyces pombe cells take up D-gluconate, as an alternative carbon source for growth, during glucose starvation or when cultured on glycerol-containing medium. Gluconate uptake is not detectable while cells are growing logarithmically on glucose. The addition of D-glucose as well as its non-metabolizable analogues to glycerol-grown cells causes an immediate loss of gluconate transport within 1 min. The reversible down-regulation of the gluconate carrier occurs after glucose has been internalized. This regulation is triggered not only by D-glucose but also by extracellular cAMP even in the absence of the cAMP-dependent protein kinase (PKA1).
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Caspari T,Urlinger Sdoi
10.1016/0014-5793(96)01052-6subject
Has Abstractpub_date
1996-10-21 00:00:00pages
272-6issue
2-3eissn
0014-5793issn
1873-3468pii
0014-5793(96)01052-6journal_volume
395pub_type
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