Abstract:
:A bovine anterior pituitary polypeptide that stimulates the replication of rat and human adipocyte precursors has been purified. Its Mr is 44 000-53 000 and its isoelectric point is 9.8-10.3. While pituitary basic fibroblast growth factor is equally mitogenic on adipocyte precursors and skin fibroblasts, the polypeptide described here is selectively more active on the precursors. We postulate that this adipocyte growth factor plays a physiological role by modulating the number of adipocyte precursors.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Lau DC,Roncari DA,Yip DK,Kindler S,Nilsen SGdoi
10.1016/0014-5793(83)80651-6subject
Has Abstractpub_date
1983-03-21 00:00:00pages
395-8issue
2eissn
0014-5793issn
1873-3468pii
0014-5793(83)80651-6journal_volume
153pub_type
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