Abstract：
:Recent developments in the regulation of testicular Leydig-cell function support the following conclusions. (1) Enzymic activities involved in steroid production in the testis are mainly localized in Leydig cells. The aromatase enzyme complex for oestrogen production appears to be localized in Leydig cells as well as in Sertoli cells. (2) LH- (or hCG-) induced alterations of Leydig cells depend on dose and duration of exposure of the cell to the hormone. Locally produced oestradiol is probably involved in the inhibition of steroidogenesis. (3) The stimulatory action of LH on Leydig cells involves different proteins in concert with the activation of the cleavage activity of mitochondrial cholesterol side-chain. However, most of the functional properties of these proteins are yet unknown. (4) Different populations of Leydig cells are present in the testis. These different cell populations can be characterized by quantitatively and qualitatively different responses to hormones.
journal_name
Mol Cell Endocrinoljournal_title
Molecular and cellular endocrinologyauthors
Rommerts FF,Brinkman AOdoi
10.1016/0303-7207(81)90026-5subject
Has Abstractpub_date
1981-01-01 00:00:00pages
15-28issue
1eissn
0303-7207issn
1872-8057journal_volume
21pub_type
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journal_title：Molecular and cellular endocrinology
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更新日期：1992-02-01 00:00:00
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更新日期：2013-04-10 00:00:00
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更新日期：2015-06-15 00:00:00
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pub_type： 杂志文章
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更新日期：1976-05-01 00:00:00
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journal_title：Molecular and cellular endocrinology
pub_type： 杂志文章
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journal_title：Molecular and cellular endocrinology
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更新日期：2013-05-22 00:00:00
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journal_title：Molecular and cellular endocrinology
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