Abstract：
:Synthesis of murine gamma interferon (MuIFN gamma) by phytohemagglutinin (PHA)-stimulated spleen cells was inhibited in a dose-dependent manner by graded concentrations of tunicamycin or 2-deoxy-glucose, both of which inhibit glycosylation. The homologous (murine) and heterologous (rat) antiviral activities of the MuIFN gamma preparations secreted in the presence of the various concentrations of either glycosylation inhibitor were reduced to similar degrees. MuIFN gamma synthesized in the presence of tunicamycin (tunicamycin-MuIFN gamma) exhibited a lower molecular weight (MW), a lack of binding to immobilized Concanavalin-A (Con A), and different charge properties when compared to MuIFN gamma produced in absence of inhibitor (control-MuIFN gamma). Potent rabbit and rat neutralizing antibodies raised against a control-MuIFN gamma subcomponent, isolated by its specific binding to a Con A affinity column, neutralized the antiviral activity of tunicamycin-MuIFN gamma to the same degree as the immunogen.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Havell EA,Spitalny GLdoi
10.1007/BF01310659subject
Has Abstractpub_date
1984-01-01 00:00:00pages
195-207issue
2-3eissn
0304-8608issn
1432-8798journal_volume
80pub_type
杂志文章abstract：:The sequence variability of Barley yellow dwarf virus-PAV (PAV) and Barley yellow dwarf virus-MAV (MAV) was studied by comparing 502 nucleotides from the coat protein-encoding region of six isolates from Latvia and four from Sweden. The diversity within MAV was low (>97% sequence identity), also when compared to isola...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-003-0242-2
更新日期：2004-04-01 00:00:00
abstract：:The nucleotide sequence of the 3' terminal region of the Australian isolate of papaya ringspot virus type W [PRSV-W (Aust)] was determined. An open reading frame (864 bp), encoding the putative coat protein gene, occurs upstream of the putative 3' untranslated region (206 bp) and poly(A) tail. A 23 amino acid sequence...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01317141
更新日期：1992-01-01 00:00:00
abstract：:Between 2005 and 2011, 23 lineages of circulating vaccine-derived polioviruses (cVDPVs) were detected in Nigeria with nonstructural region (NSR) of non-polio enterovirus C (NPEV-C) origin. However, no information exists on NPEV-C strains recombining with oral poliovirus type 2 vaccine strains (OPV2) to make type 2 cVD...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-014-2322-x
更新日期：2015-03-01 00:00:00
abstract：:Lymphocytic chorimeningitis virus (LCMV), the prototype arenavirus, and Lassa virus (LASV), causative agent of Lassa hemorrhagic fever (LHF), belong to the Old World group of the family Arenaviridae. Both viruses have extensive strain diversity and significant variations in lethality and pathogenicity for man and expe...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-004-0385-9
更新日期：2004-12-01 00:00:00
abstract：:Poliovirus induces bcl-2-independent apoptosis in the human U937 promonocytic cell line [28]. Here we describe that this cell death, induced after viral infection, correlates with the modulation of the protooncoprotein Bcl-xl. Furthermore, poliovirus infection decreases the detected Bcl-xl in a U937 clone that overexp...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-002-0881-8
更新日期：2002-12-01 00:00:00
abstract：:We investigated the cis-acting sequences of the promoter regulating the gene encoding the glycoprotein C (gC) of bovine herpesvirus 1 (BoHV-1), a gene of the gamma1 class. S1 nuclease protection assays revealed that gC transcription initiated predominantly at position C18281 of the viral genome, corresponding to 21 an...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-002-0898-z
更新日期：2003-01-01 00:00:00
abstract：:In vivo transfection by intramuscular injection with plasmids expressing the immunogenic proteins of microbial pathogens has considerable potential as a vaccination strategy against many pathogens of both man and animals. Here we report that weanling mice given a single intramuscular injection of 50 micrograms of a pl...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01718332
更新日期：1996-01-01 00:00:00
abstract：:In February 2008, five patients were infected with the H1N1 subtype of influenza A virus in one hospital ward for immunocompromised patients at a hospital in North Rhine-Westphalia, Germany. All of these patients had an established haematologic disease and tested positive either for viral RNA or antigen shortly after ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-010-0771-4
更新日期：2010-11-01 00:00:00
abstract：:A competitive-type solid phase radioimmunoassay (RIA) was developed for the detection of antibody to bovine polyomavirus. Comparison of RIA and counter-immunoelectrophoresis (CIE) results on 273 cattle sera indicated that both techniques were detecting antibody of like specificity. Human sera from 256 blood donors, 21...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01315306
更新日期：1986-01-01 00:00:00
abstract：:Genetic relationships between the genome segments of six cypovirus (CPV) isolates were analysed by RNA cross-hybridisation. These included three type 1 viruses and single isolates of types 2, 5 and 12, which collectively are identical to those previously compared by serology and electrophoresis [Mertens et al. (1989),...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050525
更新日期：1999-01-01 00:00:00
abstract：:Pigeon circovirus (PiCV) is taxonomically classified as a member of the Circovirus genus, family Circoviridae. The virus contains a single stranded DNA genome of approximately 2 kb, with minor length variations among different isolates. The occurrence of PiCV infections in pigeons (Columba livia) has been documented w...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-018-3990-8
更新日期：2018-11-01 00:00:00
abstract：:Allexiviruses are economically important garlic viruses that are involved in garlic mosaic diseases. In this study, we characterized the allexivirus cysteine-rich protein (CRP) gene located just downstream of the coat protein (CP) gene in the viral genome. We determined the nucleotide sequences of the CP and CRP genes...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-018-3749-2
更新日期：2018-06-01 00:00:00
abstract：:We have compared the RNA synthesis of alfalfa mosaic virus in complete (by RNAs 1, 2 and 3) and incomplete infections (by RNAs 1 and 2) of cowpea protoplasts. Both viral RNA polymerase activity and accumulation of viral RNA were measured. By annealing RNA in solution with 32P-labelled probes of plus and minus polarity...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050305
更新日期：1998-01-01 00:00:00
abstract：:RNA 3 of alfalfa mosaic virus (AMV) encodes the 5'-proximal movement protein (MP) gene and the 3'-proximal coat protein (CP) gene which is expressed from a subgenomic RNA. Several strategies were explored to use this RNA as a vector for expression of the green fluorescent protein (GFP) in Nicotiana tabaccum plants exp...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050170125
更新日期：2001-01-01 00:00:00
abstract：:Two herpes simplex type 1 (HSV-1) recombinant viruses carrying the hepatitis C virus (HCV) NS5A open reading frame under the control of the cytomegalovirus immediate early (IE) or a herpes simplex chimeric promoter (alpha 4 gamma 1UL19) were constructed and characterized. Expression studies showed that both HSV-NS5A r...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-002-0925-0
更新日期：2003-02-01 00:00:00
abstract：:By reverse transcription (RT)-nested polymerase chain reaction (PCR), hepatitis E virus (HEV) RNA was simultaneously detected in the livers of aborted fetuses and in fecal and serum samples from their sows, obtained from two of 14 farms tested. Sequence and phylogenetic analyses showed that these HEVs belonged to geno...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-010-0679-z
更新日期：2010-07-01 00:00:00
abstract：:Three sets of primers to detect foot-and-mouth disease virus (FMDV) using multiplex RT-PCR were designed based on several reference nucleotide sequences, and their reaction conditions were determined. By testing ten-fold serial dilutions of FMDV, the sensitivity of multiplex RT-PCR is 100 times higher than conventiona...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-007-1082-y
更新日期：2008-01-01 00:00:00
abstract：:Molecular variability was assessed for 18 isolates of cowpea mild mottle virus (CPMMV, genus Carlavirus, family Betaflexiviridae) found infecting soybean in various Brazilian states (Bahia, Goiás, Maranhão, Mato Grosso, Minas Gerais, Pará) in 2001 and 2010. A variety of symptoms was expressed in soybean cv. CD206, ran...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-013-1879-0
更新日期：2014-04-01 00:00:00
abstract：:Oncogene-containing retroviruses are generated by recombination events between viral and cellular sequences, a phenomenon called "oncogene capture". The captured cellular genes, referred to as "v-onc" genes, then acquire new oncogenic properties. We report a novel feline leukemia virus (FeLV), designated "FeLV-AKT", t...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-016-3192-1
更新日期：2017-04-01 00:00:00
abstract：:Use of Urografin and Conray for the equilibrium centrifugation of viruses is described. These pharmaceuticals, which consist of iodinated arylic compounds, reach densities of 1.6 g/cm3 and have low intrinsic viscosities. Poliovirus, Newcastle disease virus, and lymphocytic choriomeningitis virus were centrifuged to eq...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01318245
更新日期：1975-01-01 00:00:00
abstract：:A virus associated with yellow-to-purple ringspot on honeysuckle plants has been detected and tentatively named honeysuckle ringspot virus (HnRSV). The complete nucleotide sequence of HnRSV from infected honeysuckle has been determined. The genomic RNA of HnRSV is 3,956 nucleotides in length and is predicted to contai...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-011-1009-9
更新日期：2011-09-01 00:00:00
abstract：:Segment 10, encoding nonstructural proteins 3 (NS3) and 3a (NS3a) of epizootic haemorrhagic disease virus serotype 1 (EHDV-1) was sequenced. Computer motif recognition programs were used for interpretation of the sequence data to predict a structure for NS3. Integral membrane protein theories were then applied to prod...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01309968
更新日期：1995-01-01 00:00:00
abstract：:Utilizing co-transfection of DNA from glycoprotein gB- strain of HSV1 and cloned fragments of several simian alpha-herpesviruses containing the UL26, UL27 (gB glycoprotein), and UL28 gene homologs, replication-competent recombinant viruses were produced. Genetic analysis of one HSV1/SA8 recombinant (HSV1/SgB) demonstr...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050114
更新日期：1997-01-01 00:00:00
abstract：:Eight human papillomavirus (HPV) types including four cutaneous HPV types (HPV-5, HPV-8, HPV-20 and HPV-38) and four mucosal HPV types (HPV-6, HPV-11, HPV-16 and HPV-18) were selected for this miRNA study. Pre-miRNAs were predicted using a computer programme, and the conserved mature miRNAs were compared to currently ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-011-0974-3
更新日期：2011-07-01 00:00:00
abstract：:The receptor for adeno-associated virus serotype 2 (AAV2) in Purkinje cells has not been identified, but based on work carried out in non-neuronal cell lines, heparan sulfate proteoglycan is thought to act as a primary receptor, with basic fibroblast growth factor receptor-1 being reported as a co-receptor. In this st...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-008-0222-7
更新日期：2008-01-01 00:00:00
abstract：:Influenza virus A/WSN/33 forms large plaques (> 3 mm diameter) on MDCK cells whereas A/Aichi/2/68 forms only small plaques (< 1 mm diameter). Fast growing reassortants (AWM), isolated by mixed infection of MDCK cells with these two virus strains in the presence of anti-WSN antibodies, all carried the M gene from WSN. ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01313769
更新日期：1993-01-01 00:00:00
abstract：:Blot hybridization analysis of infected bovine herpesvirus 1 (BHV-1) cellular RNA isolated at various times post infection and after treatment with specific metabolic inhibitors was used to characterize transcription of the BHV-1 Cooper isolate. Synthesis of BHV-1 RNA was detected as early as 3 h post infection and re...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01316744
更新日期：1991-01-01 00:00:00
abstract：:Although surfactant-secreting type II alveolar cells have been shown to be damaged during influenzavirus pneumonia, little is known about the effects of surfactant replacement therapy. We have developed a mouse influenza model, in which viral infection can be localized to the upper respiratory tract or to both the upp...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050535
更新日期：1999-01-01 00:00:00
abstract：:Since late 2018, foot-and-mouth disease (FMD) has reemerged and rapidly swept through pig farms in North and Central Vietnam, despite widespread use of commercial FMD vaccines. To investigate the FMD virus (FMDV) strains responsible for the current epidemics, 40 FMDV samples were collected from 17 provinces during Nov...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-020-04763-8
更新日期：2020-11-01 00:00:00
abstract：:Amino acid positions recognized by monoclonal antibodies (MAbs) in the influenza A virus nucleoprotein (NP) have been reported. As these residues were scattered in the three-dimensional (3D) structure of NP, no patterns of the architecture of antibody-binding sites could be inferred. Here, we used site-specific mutage...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-013-1952-8
更新日期：2014-06-01 00:00:00
