A model for the membrane topology of the NS3 protein as predicted from the sequence of segment 10 of epizootic haemorrhagic disease virus serotype 1.

Abstract:

:Segment 10, encoding nonstructural proteins 3 (NS3) and 3a (NS3a) of epizootic haemorrhagic disease virus serotype 1 (EHDV-1) was sequenced. Computer motif recognition programs were used for interpretation of the sequence data to predict a structure for NS3. Integral membrane protein theories were then applied to produce a general topological model for the EHDV-1 NS3 protein. Homology was observed between EHDV-1 NS3 integral membrane motifs and those similarly observed in the cognate proteins of other orbiviruses.

journal_name

Arch Virol

journal_title

Archives of virology

authors

Jensen MJ,Wilson WC

doi

10.1007/BF01309968

subject

Has Abstract

pub_date

1995-01-01 00:00:00

pages

799-805

issue

4

eissn

0304-8608

issn

1432-8798

journal_volume

140

pub_type

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