Analysis of genetic variation of porcine circovirus type 2 within pig populations in central China.

Abstract:

:In order to investigate the genetic diversity of porcine circovirus type 2 (PCV2), 284 clinical tissue samples were collected from different pig farms in central China from 2015 to 2017. A total of 162 tissue samples (162/284, 57.04%) were positive for PCV2 by PCR, and subsequently, the complete genome of 36 of these PCV2 samples was cloned and sequenced. The sequencing results showed that 37 complete PCV2 sequences were obtained from 36 PCV2-positive clinical samples. These PCV2 strains were relatively conserved and extremely homologous to the representative classical PCV2 strains. Of these, 20 PCV2 strains belonged to genotype PCV2d, 14 belonged to PCV2b, and three others belonged to PCV2a. Coinfection with PCV2b and PCV2d was identified in one sample (DF-2). These results show that PCV2d may be gradually replacing PCV2b as the predominant PCV2 genotype in central China, and that other genotypes also exist in individual regions. The results of this study will aid in our understanding of the molecular epidemiology of PCV2.

journal_name

Arch Virol

journal_title

Archives of virology

authors

Xu PL,Zhao Y,Zheng HH,Tian RB,Han HY,Chen HY,Zheng LL

doi

10.1007/s00705-019-04205-0

subject

Has Abstract

pub_date

2019-05-01 00:00:00

pages

1445-1451

issue

5

eissn

0304-8608

issn

1432-8798

pii

10.1007/s00705-019-04205-0

journal_volume

164

pub_type

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