Abstract:
:Virus-like particles (VLP), morphologically similar to togavirus particles, were detected in the sera of chimpanzees and humans with chronic non-A, non-B (NANB) hepatitis. Particles resembling the virus were also found in the cytoplasm of hepatocytes obtained from NANB hepatitis infected chimpanzees. Furthermore, two chimpanzees inoculated with materials containing the VLP developed NANB hepatitis. These results strongly suggest that the VLP may be closely associated with the agent of NANB hepatitis.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Abe K,Kurata T,Shikata Tdoi
10.1007/BF01315557subject
Has Abstractpub_date
1989-01-01 00:00:00pages
351-5issue
3-4eissn
0304-8608issn
1432-8798journal_volume
104pub_type
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