Non-A, non-B hepatitis: visualization of virus-like particles from chimpanzee and human sera.

Abstract:

:Virus-like particles (VLP), morphologically similar to togavirus particles, were detected in the sera of chimpanzees and humans with chronic non-A, non-B (NANB) hepatitis. Particles resembling the virus were also found in the cytoplasm of hepatocytes obtained from NANB hepatitis infected chimpanzees. Furthermore, two chimpanzees inoculated with materials containing the VLP developed NANB hepatitis. These results strongly suggest that the VLP may be closely associated with the agent of NANB hepatitis.

journal_name

Arch Virol

journal_title

Archives of virology

authors

Abe K,Kurata T,Shikata T

doi

10.1007/BF01315557

subject

Has Abstract

pub_date

1989-01-01 00:00:00

pages

351-5

issue

3-4

eissn

0304-8608

issn

1432-8798

journal_volume

104

pub_type

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