Abstract：
:Among the four flavonoids tested quercetin and morin proved to be significantly effective against lethal Mengo virus-induced encephalitis in mice when the drugs were adminsitered orally (p.o.). With subcutaneous (s.c.) administration all four drugs failed to prevent mortality in the infected mice. Quercetin produced maximum protective response in intraperitoneally (i.p.) or intranasally (i.nas.) infected mice when administered twice daily at doses of 20 mg/kg for a period of not less than four days. Single injections of the full daily dose of drug failed to prevent deaths in mice. Treatment must be begun at the time of, or prior to, virus inoculation. Delayed initiation of treatment was ineffective in preventing mortality.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Veckenstedt A,Béládi I,Mucsi Idoi
10.1007/BF01315089subject
Has Abstractpub_date
1978-01-01 00:00:00pages
255-60issue
3eissn
0304-8608issn
1432-8798journal_volume
57pub_type
杂志文章abstract：:Peritoneal exudate cells (PEC) of DBA/2 mice, after 7 days of in vitro preculture and consisting of virtually 100 per cent macrophages, were able to support the replication of Herpes Simplex Virus type 1 strain WAL (HSV). Using a standard medium based on Dulbecco's Modified Eagle Medium (D-MEM), no virus replication w...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01309370
更新日期：1984-01-01 00:00:00
abstract：:Purified DNA from 45 isolates of suis herpes virus 1 (SHV1) collected between 1980 and 1987 from clinical outbreaks of Aujeszky's disease on French farms was compared by restriction fragment pattern (RFP) analysis. The BamHI generated RFPs were found to be distinguishable, confirming RFP analysis as a potential epidem...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01323161
更新日期：1990-01-01 00:00:00
abstract：:Antibody and cell-mediated immune responses were measured in rabbits immunized with live, UV inactivated herpes simplex virus or with a subunit vaccine containing envelope proteins. All the types of immunization procedures induced the production of antibody as well as a specific cellular immunity. Furthermore, the sub...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01317862
更新日期：1976-01-01 00:00:00
abstract：:A bovine monoclonal antibody specific for bovine viral diarrhoea virus (BVDV) recognized all the reference strains of BVDV and over 90% of the field isolates tested. It neutralized the virus and precipitated a 56 k-58 k viral protein. ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01316756
更新日期：1991-01-01 00:00:00
abstract：:In order to differentiate recent isolates of avian infectious bronchitis virus (IBV) in Taiwan, polymerase chain reaction (PCR), restriction fragment length polymorphism (RFLP), and direct sequencing methods were used to type 25 IBV Taiwan isolates. Two conserved sequences that flank the hypervariable region I (HVR I)...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01718291
更新日期：1996-01-01 00:00:00
abstract：:An arracacha (Arracacia xanthorrhiza) plant collected in Brazil was found to be infected by a new virus. This viral isolate (named C17) systemically infected Nicotiana benthamiana and Apium graveolens. A polyclonal antibody was raised, and analysis of our arracacha germplasm collection showed a high infection rate of ...
journal_title：Archives of virology
pub_type： 杂志文章,评审
doi：10.1007/s00705-008-0289-1
更新日期：2009-01-01 00:00:00
abstract：:We investigated the transforming domain of a recently isolated feline sarcoma virus (TP1-FeSV) which encodes a fgr-related tyrosine kinase expressed as a gag-fgr fusion protein. The gag portion was removed and replication-competent expression vectors (RCAS) with inserted v-fgr sequences were established. Chicken embry...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01379113
更新日期：1994-01-01 00:00:00
abstract：:Analysis of a loquat tree with leaf curl symptoms by deep sequencing revealed a novel virus with a single-stranded RNA genome, for which the name "loquat virus A" (LoVA) was proposed. The complete genome sequence comprised 7553 nucleotides (nt) and an additional poly(A) tail at the 3' terminus. Sequence comparisons of...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-019-04444-1
更新日期：2020-01-01 00:00:00
abstract：:To provide information on the mechanism of attenuation of a Newcastle disease vaccine strain, TCND, we compared it with the parental virulent strain California 11,914 (CAL) biologically and genetically. It was found that TCND bore the fusion protein of virulent type, consisting of a pair of dibasic amino acid residues...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050361
更新日期：1998-01-01 00:00:00
abstract：:DNA polymerase (DNApol) is present in all baculoviruses and plays a crucial role in viral DNA replication. Previously we showed that the DNApol of the alphabaculovirus group II Spodoptera litura nucleopolyhedrovirus (SpltNPV) could partially substitute for the DNApol of a group I alphabaculovirus, Autographa californi...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-017-3468-0
更新日期：2017-11-01 00:00:00
abstract：:During the surveillance for avian influenza viruses (AIVs) in live poultry markets in Eastern China, in 2016, a novel reassortant H7N6 AIV was isolated from a chicken. Phylogenetic analysis showed that this strain received its genes from H9N2, H7N9 and H5N6 AIVs infecting poultry in China. This strain showed moderate ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-017-3219-2
更新日期：2017-05-01 00:00:00
abstract：:Providence Virus (PrV) is a non-envoloped, T = 4 icosahedral beta-tetravirus that undergoes autocatalytic cleavage of its coat protein precursor after capsid assembly. This is also a well characterized function of Nudaurelia capensis omega virus (NomegaV), a member of the related omegatetraviruses, whose x-ray structu...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-005-0637-3
更新日期：2006-01-01 00:00:00
abstract：:A wheat-infecting furovirus found in Tompkins County, New York, U.S.A. was identified as a strain of Soil-borne wheat mosaic virus (SBWMV) by means of sequence analyses of portions of its RNA 1 and 2. The nucleotide sequences of several of its genes differed by c. 9 to 12% from those of the corresponding genome region...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050200011
更新日期：2002-03-01 00:00:00
abstract：:RNase resistance analyses of native, heat-denatured and self-annealed L and S species of Machupo virion RNA revealed the presence of complementary sequences. Self-annealing was concentration-dependent. The data indicate, that complementary sequences were present in separate RNA strands. ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01310900
更新日期：1986-01-01 00:00:00
abstract：:The genome of a Spanish isolate of Broad bean wilt virus-1 (BBWV-1) was completely sequenced and compared with available sequences of other isolates of the genus Fabavirus (BBWV-1 and BBWV-2). This consisted of two RNAs of 5814 and 3431 nucleotides, respectively, and their organization was similar to that of other mem...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-005-0582-1
更新日期：2005-10-01 00:00:00
abstract：:117F and R are subgroup I and II cucumber mosaic virus (CMV) strains, respectively. Whereas I17F induces severe symptoms on all hosts so far tested, R induces generally mild symptoms, except on Nicotiana glutinosa, on which it causes leaf blistering and severe stunting. Pseudorecombinants and recombinants, based on RN...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050510
更新日期：1999-01-01 00:00:00
abstract：:Heparin added together with murine L cell interferon inhibited the development of antiviral activity in mouse L cells. When added after interferon treatment, heparin had no effect on antiviral activity. There was also no inhibition of interferon action in L cells treated with heparin before addition of interferon. On ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01314146
更新日期：1986-01-01 00:00:00
abstract：:Poultry production is an important sector of agriculture in Sri Lanka; however, there is a lack of information regarding circulation of infectious bronchitis virus (IBV). RNA was extracted from chicken tissues, subjected to IBV S1 RT-PCR, and sequenced. Overall, 19 out of 34 (55.88 %) samples were IBV positive and con...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-016-2831-x
更新日期：2016-06-01 00:00:00
abstract：:Ten strains of avian infectious bronchitis virus (IBV) were titrated as plaque-forming units in primary chick embryo fibroblast cells. In the absence of trypsin, plaques were only formed by Beaudette-42 and Iowa-609 strains. When trypsin was incorporated in the overlay medium of cell monolayers, all the IBV strains te...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01320246
更新日期：1981-01-01 00:00:00
abstract：:During the course of hominoid evolution, a new transcript variant of the GSDML (gasdermin-like protein) gene was formed by the integration of the antisense-oriented HERV-H (human endogenous retrovirus) LTR (long terminal repeat) element. To investigate regions that are critical for transcriptional regulation of the GS...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-008-0105-y
更新日期：2008-01-01 00:00:00
abstract：:Chilli veinal mottle virus (ChiVMV) is an important plant pathogen with a wide host range. The genetic structure of ChiVMV was investigated by analyzing the coat protein (CP) genes of 87 ChiVMV isolates from seven Asian regions. Pairwise F ST values between ChiVMV populations ranged from 0.108 to 0.681, indicating a s...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-016-2761-7
更新日期：2016-05-01 00:00:00
abstract：:Treatment of a mouse macrophage cell line Mk1 with pokeweed mitogen (PWM) either before or during but not after virus inoculation resulted in an enhancement of dengue virus (DV) infection. The infection enhancement was primarily due to an increase in the number of DV-infected cells but not to increased virus productio...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01379106
更新日期：1994-01-01 00:00:00
abstract：:Virazole (1, beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide = Ribavirin), a synthetic nucleoside analogue, has been successfully used against tomato spotted wilt virus (TSWV) in tomato and tobacco plants. In tomato, the most efficient concentration to control TSWW was 500 mg/l while in tobacco, concentrations of 10...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01315037
更新日期：1980-01-01 00:00:00
abstract：:A coxsackievirus B3 (CVB3) cDNA clone, upon transfection of HeLa cells, produces CVB3 capable of induction of cardiac inflammation in C3H/He mice by day 8 post inoculation (p.i.). Liver and serum are cleared of CVB3 by day 8 p.i., but CVB3 persists in the heart through day 14. The nucleotide sequence and the predicted...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01317202
更新日期：1992-01-01 00:00:00
abstract：:Tax oncoprotein of Human T-lymphotropic virus 1 (HTLV-1) has been proposed to dysregulate the expression of a number of cellular genes, many of which play a critical role for cell proliferation. Our initial data demonstrated that the immediate-early gene butyrate response factor 1 ( BRF1) was upregulated in HTLV-1-inf...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-003-0114-9
更新日期：2003-09-01 00:00:00
abstract：:The gene encoding the capsid protein of a genogroup I Norwalk-like virus (NLV) (Hu/NLV/Stav/95/Nor) was cloned and expressed in insect cells using a baculovirus vector. The His-tagged recombinant capsid protein (rStav) was antigenic and immunogenic, showed an apparent molecular weight of approximately 68 kD in protein...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050665
更新日期：2000-01-01 00:00:00
abstract：:Bovine viral diarrhoea virus 1 (BVDV-1) and Bovine viral diarrhoea virus 2 (BVDV-2) are two recognised bovine pestivirus species of the genus Pestivirus. Recently, a pestivirus, termed SVA/cont-08, was detected in a batch of contaminated foetal calf serum originating from South America. Comparative sequence analysis s...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-009-0419-4
更新日期：2009-01-01 00:00:00
abstract：:Reassortants between a low-pathogenic avian influenza virus strain A/Duck/Primorie/2621/2001 (H5N2) and a high-yield human influenza virus strain A/Puerto Rico/8/34 (H1N1) were generated, genotyped and analyzed with respect to their yield in embryonated chicken eggs, pathogenicity for mice, and immunogenicity. A reass...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-006-0931-8
更新日期：2007-01-01 00:00:00
abstract：:Tissues of the central nervous system (CNS) of cynomolgus monkeys were examined by electron microscopy after intraspinal inoculation of enterovirus 71 (E71). A characteristic finding was the appearance of numerous membrane-bound vesicles (Mbvs) in affected motoneurons. Similar Mbvs were also present in E71-infected cy...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01314120
更新日期：1985-01-01 00:00:00
abstract：:We have sequenced the complete genome of an isolate of Banana streak virus from banana cv. 'Mysore' and show that it is sufficiently different from a previously characterised isolate from cv. 'Obino l'Ewai' to warrant recognition as a distinct species, for which the name Banana streak Mysore virus (BSMysV) is proposed...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-004-0471-z
更新日期：2005-04-01 00:00:00
